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Objective To evaluate the feasibility, acceptability, and efficacy of an after-school team sports program for reducing weight gain in low-income overweight children. Design Six-month, 2-arm, parallel-group, pilot randomized controlled trial. Setting Low-income, racial/ethnic minority community. Participants Twenty-one children in grades 4 and 5 with a body mass index at or above the 85th percentile. Interventions The treatment intervention consisted of an after-school soccer program. The “active placebo” control intervention consisted of an after-school health education program. Main Outcome Measures Implementation, acceptability, body mass index, physical activity measured using accelerometers, reported television and other screen time, self-esteem, depressive symptoms, and weight concerns. Results All 21 children completed the study. Compared with children receiving health education, children in the soccer group had significant decreases in body mass index z scores at 3 and 6 months and significant increases in total daily, moderate, and vigorous physical activity at 3 months. Conclusion An after-school team soccer program for overweight children can be a feasible, acceptable, and efficacious intervention for weight control. Trial Registration clinicaltrials.gov Identifier:NCT00186173