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Introduction: Healthcare staffs are first-line fighters who handle COVID-19 patients.They face a high risk of infection every day, and are subject to long and distressingwork hours in order to meet health needs. Aim of work: To evaluate the psychologicalimpact of COVID-19 pandemic on health care workers (HCWs). Materials andMethods: All categories of health care workers in Egypt were invited to participatein the study through sharing the link to online professional groups between 21st Juneto 9th July 2020. The survey included a self-administered- Arabic questionnaireincluding information related to socio- demographic characteristics, medical historyincluding diseases and medications, work characteristics and COVID -19 experienceof the studied participants. The survey also included validated Depression, Anxiety,and Stress Scales (DASS-21) and 7 items work-related burnout Copenhagen BurnoutInventory (CBI). Results: The total number of health care workers who shared in thestudy was 764. There were psychological disorders of varying degrees in the formof depression (41.5%), anxiety (67%), and stress (27.7 %). Working as nurses, age

Objective: Little is known about potential adverse health effects of in utero exposure to organophosphate (OP) pesticides. The aim of this study was to assess the effect of organophosphate pesticide exposure during pregnancy and adverse perinatal outcome. Subject and Methods: This prospective study was conducted during the period from March 2013 to March 2105 and included two groups of pregnant women, 40 exposed women and 100 unexposed women as a control group. Both groups were matched for age, socioeconomic class educational level and body mass index. Serum acetyl cholinesterase (AChE) was measured in all participants at 20-22 weeks’ gestation. All women were followed up till delivery. Perinatal outcome was assessed in terms of gestational age at delivery, birth weight, head circumference and body length of the newborn. Results: Exposed participants exhibited significantly shortened gestational age, low birth weight and smaller head circumference than controls. There was a positive correlation between reduced level of AChE and gestational age and birth weight. Conclusions: Our results confirmed the association between organophosphate pesticide exposure during pregnancy and adverse perinatal outcome in terms of reduced gestational age, low birth weight and small head circumference.