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The upper part of a pier wharf on the sea is usually made up of the horizontal panels with both longitudinal and transverse beams above the still water level. To estimate the wave force on the structures, many scholars have conducted theoretical and experimental researches, and proposed a lot of empirical equations concerning the wave force and corresponding pressure distribution. Nevertheless, due to the complex factors and changeable girder systems, the generation mechanism of wave uplifting forces has not been fully understood so far, and the discreteness and limitations of experimental data lead to vastly difference between various empirical formulas, which causes that the calculated wave forces using different formulas differ by ten times. Therefore, it is necessary to determine wave the uplifting force and horizontal force on girder structures by conducting physical model experiments. In the present study, the physical model experiments with a scale of 1:40 are used to measure the wave forces on the wharf platform, abutment and pile foundations under different combinations of water level and waves at Petrochemical Wharf, Haicang Harbor, Xiamen. The experiment results have already been adopted in practice by some design institutes.

To build a scientific and efficient Distribution Management System (DMS), it is necessary to achieve sharing of data and avoid information silos. The IEC61968-based information exchange platform, which adopts IEC61968 Information Exchange Model (IEM) and interface specification, is an effective means to resolve the above problem, realizing seamless data exchange and sharing of data between various subsystems. It is shown by applications that, the adapters for multi-system interfaces are simple and practical, ensuring efficient communication for data exchange, and meeting requirements for data exchange and sharing of data between various subsystems. This platform effectively solves the problem of information silos, laying a solid foundation for development of smart grid information technology.

Aim of the study Hepatocellular carcinoma suppressor 1 (HCCS1) has been identified as a tumor suppressor gene in the high-frequency loss of heterozygosity (LOH) region on chromosome 17p13.3 in hepatocellular carcinoma (HCC). There was also a high frequency of LOH on chromosome 17p13.3 in non-small cell lung cancer (NSCLC). Therefore, the aim of this study was to explore the expression of HCCS1 in NSCLC as well as its clinical significance. Material and methods Real-time PCR and immunohistochemistry were performed to detect the expression level of HCCS1 mRNA and protein in NSCLC and noncancerous tissues, respectively. Further, we explored the relationship between HCCS1 expression and various clinical features in NSCLC. Results The mRNA and protein expression of HCCS1 were both significantly lower in NSCLC samples than those in noncancerous tissues. That is, the mRNA level of HCCS1 was 0.0044 ±0.0036 and 0.0067 ±0.0054 in NSCLC samples and noncancerous tissues, respectively. The protein level of HCCS1 was 4.67 ±1.15 and 6.13 ±1.24 in NSCLC samples and noncancerous tissues, respectively. Importantly, this difference in expression was significantly correlated with tumor lymph node metastasis (TNM) in NSCLC (p < 0.05), but not with gender and age of the patients, pathological types, TNM stages, or grades of cancers (p > 0.05). Conclusion Our results suggest that HCCS1 may be involved in NSCLC carcinogenesis.

In this paper, a Agile Model of General report system by using MDA technology is studied according to the characterstics of general report system. A architecture of agile general report system based on MDA is constructed, and report basic model by using MDA is designed for general report system. Based on MDA methodology, the basic elements and styles of report are designed into configurable model, and a PIM was built with UML for the agile general report system. The agile general report system based on MDA improves efficiency and the capability and scalbility of the whole system. The system can be applied to different system with good performance through an applied test.