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Simulation training is an inevitable choice for joint operations training. Simulation training platform is considered as the core of military deduction. It combines simulation systems and solid equipment to build the training environment, which provides the necessary conditions for the multi-level multi-area joint training. In this paper, the existing simulation training architecture technologies are reviewed. Considering the characteristics of joint training and functional requirements, an overall structural design of a simulation platform is given, and several challenges technical are discussed.

In this paper, the influence of radiation asymmetry on radiant heat transfer in the room of plane radiant air-conditioning system is analyzed. The radiation heat transfer model used in the Fanger thermal comfort equation is introduced. Using Airpak simulation analysis, it is concluded that external Windows and external walls should be taken as separate enclosure structures to calculate the PMV value. A new radiation heat transfer model was established, and the radiation heat transfer was solved under the new radiation heat transfer model. As the radiation heat transfer in the PMV equation, the thermal comfort equation was modified.

The impedance of a capacitively coupled contactless conductivity detector (C 4 D) cell was experimentally examined for different cell parameters by alternative current impedance (ACImp). The effect of the gap between the electrodes and the length of the electrodes on the impedance behavior of the C 4 D cell has been studied. As a result, the impedance of C 4 D cell is largely defined by the length of the gap between the electrodes and the length of the electrodes. The impedance increases with increasing gap between the electrodes and the length of the electrodes. It could be found that tightly coupling of the electrodes to the outer wall of the capillary is needed. The axial contactless conductometric detector can be effectively described by the simplest possible equivalent circuitry consisting of a capacitor, resistor, a second resister and a Warburg impedance. These results are helpful to understand the impedance characteristics of C 4 D cell and improve its detective performance.

An implicit finite-element code is employed to study the internal grinding process of carbon steel Q235 cirque, and its temperature field and thermal deformation are obtained. The method of thermal load calculation is proposed, a 2D finite element model is developed, and analysis steps are introduced. The diameter of the cirque is 150 mm and that of the inner hole is 56.24 mm. By adopting the clamps of surface locating and three-jaw chuck, it is found that, during the grinding process, the workpiece is in an elastic–plastic state, far from thermal-softening state. The thermal deformation of the ground cirque is basically symmetrical in a diamond shape, but the deformations of the inner circle and the outer circle are not uniform, and the inner circle thermal deformation may be negative or positive. Such different thermal displacements will produce shape error and dimension error in the inner hole. Through comparison of the two clamping modes, it is found that the precision of the surface locating is better than the three-jaw chuck. The symmetrical property of the thermal deformation of the cirque and the comparison of two clamping modes indicate that the computation is valid.

A semi-analytical method was proposed to solve the mechanics problem of stamping a sheet on elastic die. The sheet was divided into four parts according to its deformation and contact with the punch and elastic die. Analytical solutions were derived individually for each part by using elastic large deflection and plastic large deformation. Solutions were found out with MATLAB by developing a numerical algorithm. Interface forces were obtained by iteration under the compatibility conditions between the neighboring parts of the sheet. Computation shows the method is efficient.

Xi-Xi Lai, Ren-Ai Xu, Yu-Ping Li, Han Yang Department of Respiratory Medicine, The First Affiliated Hospital of Wenzhou Medical University, Wenzhou, Zhejiang, People’s Republic of China Background: Bevacizumab, a monoclonal antibody against vascular endothelial growth factor ligand, has shown survival benefits in the treatment of many types of malignant tumors, including non-small-cell lung cancer (NSCLC). We conducted this systematic review and meta-analysis to investigate the risk of the most clinically relevant adverse events related to bevacizumab in advanced NSCLC.Methods: Databases from PubMed, Web of Science, and Cochrane Library up to August 2015, were searched to identify relevant studies. We included prospective randomized controlled Phase II/III clinical trials that compared therapy with or without bevacizumab for advanced NSCLC. Summary relative risk (RR) and 95% confidence intervals were calculated using random effects or fixed effects according to the heterogeneity among included trials.Results: A total of 3,745 patients from nine clinical trials were included in the meta-analysis. Summary RRs showed a statistically significant bevacizumab-associated increased risk in three of the adverse outcomes studied: proteinuria (RR =7.55), hypertension (RR =5.34), and hemorrhagic events (RR =2.61). No statistically significant differences were found for gastrointestinal perforation (P=0.60), arterial and venous thromboembolic events (P=0.35 and P=0.92, respectively), or fatal events (P=0.29).Conclusion: The addition of bevacizumab to therapy in advanced NSCLC did significantly increase the risk of proteinuria, hypertension, and hemorrhagic events but not arterial/venous thromboembolic events, gastrointestinal perforation, or fatal adverse events. Keywords: toxicities, angiogenesis inhibitors, non-small-cell lung carcinoma, meta-analysis, safety