1. A wearable heart rate measurement device for children with autism spectrum disorder
- Author
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Zaccaria Del Prete, Filippo Manti, Livio D'Alvia, Andrea Maugeri, Erika Pittella, Francesca Fioriello, Carla Sogos, Emanuele Piuzzi, and Emanuele Rizzuto
- Subjects
Male ,medicine.medical_specialty ,Autism Spectrum Disorder ,lcsh:Medicine ,Audiology ,Article ,Autism Diagnostic Observation Schedule ,03 medical and health sciences ,Wearable Electronic Devices ,0302 clinical medicine ,Heart Rate ,Statistical significance ,Heart rate ,Medicine ,Psychology ,Humans ,0501 psychology and cognitive sciences ,Language disorder ,lcsh:Science ,Child ,Multidisciplinary ,business.industry ,05 social sciences ,lcsh:R ,medicine.disease ,ASD ,stress recognition ,joint attention ,heart rate ,measurement device ,wearable sensors ,Anticipation ,Autonomic nervous system ,Heart rate measurement ,Autism spectrum disorder ,lcsh:Q ,Female ,business ,030217 neurology & neurosurgery ,050104 developmental & child psychology ,Neuroscience - Abstract
Autism spectrum disorder (ASD) is a neurodevelopmental condition characterized by early impairment in social and communication domains and autonomic nervous system unbalance. This study evaluated heart rate (HR) as a possible indicator of stress response in children with ASD as compared to children with language disorder (LD). Twenty-four patients [mean age = 42.62 months; SD = 8.14 months,12 with ASD (10 M/2F) and 12 with LD (8 M/4F)] underwent clinical [Leiter International Performance Scale-Revised, Autism Diagnostic Observation Schedule, second edition (ADOS-2)] and physiological evaluation (HR monitoring) during five interactive activities, while wearing an HR measurement device. IQ (ASD:IQ = 103.33 ± 12.85 vs. LD:IQ = 111.00 ± 8.88, p = 0.103) and fluid reasoning on the Leiter-R Scale were within the normal range in all subjects. Increased HR during the third activity (ADOS-2 bubble play) significantly correlated with autistic symptoms (r = 0.415; p = 0.044), while correlations between ADOS-2 total score and HR during the first activity (ADOS-2 free play; r = 0.368; p = 0.077), second activity (Leiter-R figure ground subscale; r = 0.373, p = 0.073), and fifth activity (ADOS-2 anticipation of a routine with objects; r = 0.368; p = 0.076) did not quite reach statistical significance. Applying a linear regression model, we found that the ADOS-2 total score significantly influenced HR variations (p = 0.023). HR monitoring may provide a better understanding of the stress-provoking situations for children with ASD. Furthermore, it could help clinicians detect the impact of the stressful condition on the autistic core and adress treatment strategy.
- Published
- 2020