32 results on '"Masashi Kusakabe"'
Search Results
2. Assessment of surgical outcomes of off-clamp open partial nephrectomy without renorrhaphy for ≥T1b renal tumours
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Shuji Kameyama, Hiroki Inatsu, Masashi Kusakabe, Tadashi Yoshimatsu, Teppei Morikawa, Yoshiki Ambe, Taro Teshima, Yoshiyuki Shiga, Yasushi Inoue, Norihide Shirakawa, Shunsuke Imai, Ryo Amakawa, and Masaki Nakamura
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0301 basic medicine ,Surgical results ,medicine.medical_specialty ,Renal function ,Kidney ,Nephrectomy ,Resection ,03 medical and health sciences ,0302 clinical medicine ,Robotic Surgical Procedures ,Blood loss ,Surgical oncology ,Humans ,Medicine ,Open partial nephrectomy ,Retrospective Studies ,business.industry ,Hematology ,General Medicine ,Perioperative ,Kidney Neoplasms ,Surgery ,Treatment Outcome ,030104 developmental biology ,Clamp ,Oncology ,030220 oncology & carcinogenesis ,business ,Glomerular Filtration Rate - Abstract
To assess the surgical outcomes of off-clamp open partial nephrectomy without renorrhaphy. In the era of robot-assisted surgeries, open partial nephrectomy remains a surgical option for ≥ T1b renal tumours. Although the necessity of renal pedicle clamping and renorrhaphy in open partial nephrectomy for larger tumours remains to be discussed, reports on this issue are rare. Twenty-seven open partial nephrectomies for ≥ T1b renal tumours were performed without renal pedicle clamping or renorrhaphy. A soft coagulation system was used to control bleeding from the resection bed. Surgical results, complications, and predictors of perioperative estimated glomerular filtration rate (eGFR) preservation at 1 month and 3 months after surgery were analysed. The median estimated volume of blood loss was 420 mL. The rates of perioperative eGFR preservation were 88.9 and 87.3% at 1 and 3 months after surgery, respectively. Tumour size was an independent predictor of perioperative eGFR preservation at 1 month after surgery, whereas age and exophytic/endophytic properties of the tumour were independent predictors of perioperative eGFR preservation at 3 months after surgery. Open partial nephrectomy without renal pedicle clamping or renorrhaphy could be safely performed for ≥ T1b renal tumours, even when tumours were entirely endophytic and located close to the renal pedicle. Mild perioperative eGFR reduction was observed. Although surgical indications should be carefully considered in these cases, off-clamp open partial nephrectomy without renorrhaphy is a feasible procedure for patients with ≥ T1b renal tumours.
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- 2021
3. Pleural nodule with osteal protrusion anterior to the rib tubercle: a case report
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Masashi Kusakabe, Jun Matsumoto, Hajime Horiuchi, Noriko Hiyama, and Junichi Kazaoka
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Parietal Pleura ,Tubercle ,R895-920 ,Fibrous tissue ,Osteal protrusion ,030218 nuclear medicine & medical imaging ,Lesion ,03 medical and health sciences ,Medical physics. Medical radiology. Nuclear medicine ,0302 clinical medicine ,medicine ,Radiology, Nuclear Medicine and imaging ,Lung cancer ,Right sixth rib ,business.industry ,Nodule (medicine) ,Anatomy ,respiratory system ,medicine.disease ,Pleural nodule ,respiratory tract diseases ,Chest ,medicine.symptom ,business ,030217 neurology & neurosurgery ,Rib tubercle - Abstract
Pleural soft tissue density nodules with osteal protrusions are often detected at their characteristic site, the anterior portion of the rib tubercle. Herein, we report a pathologically proven case of this lesion. A 65-year-old man underwent surgery for primary lung cancer in the right middle lobe. Preoperative computed tomography showed a 10-mm pleural soft tissue density nodule with osteal protrusion anterior to the tubercle of the right sixth rib, and this lesion was concomitantly resected. Intraoperative findings showed that this pleural lesion originated from the parietal pleura and was pathologically diagnosed as a benign fibrous tissue. We can avoid unnecessary invasive examinations such as biopsies by recognizing these benign fibrous lesions.
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- 2021
4. MRI, CT and FDG-PET/CT findings of Wolffian tumor: four-case series
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Kaori Kuriyama, Yuichiro Kanie, Kozue Morioka, Hisataka Ito, Akihito Mitsumori, Takashi Koyama, Masashi Kusakabe, Sakiko Kageyama, and Moto Nakaya
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Adenoma ,PET/CT ,medicine.medical_treatment ,Ovary ,Malignancy ,Asymptomatic ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,0302 clinical medicine ,Fluorodeoxyglucose F18 ,Positron Emission Tomography Computed Tomography ,Medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Special Report ,Wolffian tumor ,PET-CT ,business.industry ,medicine.disease ,Magnetic Resonance Imaging ,Radiation therapy ,medicine.anatomical_structure ,Acute abdomen ,030220 oncology & carcinogenesis ,Female adnexal tumor of probable Wolffian origin ,Adnexal Diseases ,Positron-Emission Tomography ,Female ,Tomography ,medicine.symptom ,Radiopharmaceuticals ,business ,Nuclear medicine ,MRI ,CT - Abstract
Abstarct Purpose The purpose of this study is to describe the characteristic MRI, CT, and 18F-fluorodeoxyglucose-positron emission tomography/computed tomography (FDG-PET/CT) findings of Wolffian tumor. Methods We reviewed preoperative images in four surgical cases of Wolffian tumor. MRI was available for review in all cases with additional diffusion-weighted images (DWI) in three, and contrast-enhanced images in two. CT was available in three. FDG-PET/CT was obtained in two. Results Two patients were asymptomatic, while the other two presented with acute abdomen. On MRI, all tumors were well-defined masses of increased signals on T2WI. Three tumors were solid, whereas the other was solid and cystic. The normal ipsilateral ovary was identified in two patients of reproductive ages, but not in two postmenopausal patients. Tumors in two patients presented with acute abdomen were complicated by hemorrhage. All three tumors evaluated on DWI showed high intensities. Contrast-enhanced images of MRI and CT showed homogeneous enhancement as the same degree as the myometrium. On CT, one tumor contained punctate calcifications. FDG-PET/CT showed moderate FDG accumulation. Conclusion Wolffian tumors may be typically solid extraovarian tumors occasionally associated with cysts and calcifications. Although they are benign, they mimic malignancy due to high intensities on DWI and increased FDG accumulation.
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- 2021
5. Granulomatous prostatitis with high suspicion of prostatic adenocarcinoma on radiological imaging
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Hiroki Inatsu, Yoshiyuki Shiga, Masashi Kusakabe, Sakiko Miura, Norihide Shirakawa, Tadashi Yoshimatsu, Teppei Morikawa, Yasushi Inoue, Masaki Nakamura, Yoshiki Ambe, and Ryo Amakawa
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medicine.medical_specialty ,granulomatous prostatitis ,Urology ,multiparametric MRI ,Case Report ,Case Reports ,Malignancy ,Prostate ,medicine ,Granulomatous prostatitis ,Effective diffusion coefficient ,Multiparametric Magnetic Resonance Imaging ,medicine.diagnostic_test ,business.industry ,Magnetic resonance imaging ,medicine.disease ,equipment and supplies ,Diseases of the genitourinary system. Urology ,medicine.anatomical_structure ,PET ,Positron emission tomography ,apparent diffusion coefficient ,Radiology ,RC870-923 ,Differential diagnosis ,business ,urinary tract infection ,human activities ,MRI - Abstract
Introduction Granulomatous prostatitis is a benign inflammatory condition of the prostate that may mimic prostatic adenocarcinoma on magnetic resonance imaging findings. Even in the era of multiparametric magnetic resonance imaging, the differential diagnosis of granulomatous prostatitis from malignancy remains difficult. Case presentation A 69‐year‐old man with abnormal magnetic resonance imaging and positron emission tomography/magnetic resonance imaging findings, and a prostate‐specific antigen value of 2.48 ng/mL underwent prostate needle biopsy. He had a history of urinary tract infection 3 months prior to presentation. Multiparametric magnetic resonance imaging showed low‐intensity signals on T2‐weighted images, slightly high‐intensity signals on diffusion‐weighted images, and low values on apparent diffusion coefficients. The prostate imaging‐reporting and data system version 2 score was 3. Histological examination revealed granulomatous prostatitis. Conclusion For patients with preceding urinary tract infections, granulomatous prostatitis should be considered as a differential diagnosis, even when magnetic resonance imaging and positron emission tomography suggest prostatic adenocarcinoma.
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- 2021
6. Progressively increasing density of the solid center of a ground‐glass nodule in a solitary pulmonary capillary hemangioma: A case report
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Noriko Hiyama, Jun Matsumoto, Hirokazu Yamaguchi, Hirotsugu Hashimoto, Masashi Kusakabe, Teppei Morikawa, Mizuho Murakami, and Hajime Horiuchi
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0301 basic medicine ,Pathology ,medicine.medical_specialty ,Lung ,medicine.diagnostic_test ,business.industry ,Capillary hemangioma ,Chest ct ,Computed tomography ,Nodule (medicine) ,General Medicine ,Surgical specimen ,medicine.disease ,Asymptomatic ,Pathology and Forensic Medicine ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,medicine ,Radiology ,medicine.symptom ,Lung cancer ,business - Abstract
Solitary pulmonary capillary hemangiomas (SPCHs) are recently recognized, rare benign lesions that form solitary nodules owing to capillary proliferation. These lesions are usually detected incidentally as small ground-glass nodules (GGNs) on computed tomography (CT), and progressively enlarge over time. The radiological distinction from peripheral lung cancers is particularly challenging. However, to date, there have been no reports on progressive changes in the central density of SPCH on CT. An asymptomatic 49-year-old man was referred to our hospital for an abnormal shadow that was detected on chest CT during medical check-up. He was subsequently followed-up with chest CT. The nodule increased in size, and the central area became progressively denser. He underwent surgery 5 years and 10 months after the first visit owing to suspicion of lung cancer. Despite the collapse of the surgical specimen by artifacts, histopathological examination revealed a diagnosis of SPCH; collagenous fibers were found in the walls of the intralesional capillaries. The patient is presently alive without any recurrence, 6 months after the operation. In this case, the SPCH demonstrated a GGN with progressively increasing density of the central solid area on the CT. This remarkable feature made the preoperative distinction from lung cancer particularly difficult.
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- 2020
7. Reliability and validity of D‑dimer monitoring for pulmonary thromboembolism in patients with unresectable, advanced or recurrent colorectal cancer treated with bevacizumab
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Dan Kanehira, Masashi Kusakabe, Junichi Shimizu, Sachio Shimizu, Jinshi Irikuchi, Masao Yamasaki, Ryosuke Oki, Toshiaki Kato, Akihiro Hirai, and Keita Uchino
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Cancer Research ,medicine.medical_specialty ,Chemotherapy ,Bevacizumab ,Colorectal cancer ,business.industry ,Incidence (epidemiology) ,medicine.medical_treatment ,Cancer ,Combination chemotherapy ,Articles ,medicine.disease ,Asymptomatic ,Oncology ,D-dimer ,medicine ,Radiology ,medicine.symptom ,business ,medicine.drug - Abstract
Pulmonary thromboembolism (PTE) is one of the leading causes of death among cancer outpatients. The aim of the present study was to investigate the reliability and validity of D-dimer monitoring for PTE in patients with unresectable, advanced or recurrent colorectal cancer treated with bevacizumab. A total of 25 patients with advanced colorectal cancer who received bevacizumab combination chemotherapy as primary treatment were retrospectively reviewed. The selection criteria included that D-dimer tests were performed repetitively, and that chest and abdominal contrast-enhanced CT scans were completed. The D-dimer levels and the presence or absence of PTE on CT images were retrospectively examined. Four cases (16%) were detected as having asymptomatic PTE. The D-dimer values at the onset of PTE were 14.2, 4.6, 1.1 and 0.9 µg/ml. The negative predictive value was 90.5% when 3.0 µg/ml was set as the D-dimer level cutoff value. The incidence of PTE, including asymptomatic PTE, in the present study was higher compared with that reported in previous studies on various types of cancer, of various stages and treated with different chemotherapy regimens. In patients with bevacizumab-treated unresectable, advanced or recurrent colorectal cancer, the D-dimer test was found to be less useful for exclusion diagnosis; however, along with chest CT, it may be useful in the detection and diagnosis of PTE. However, the determination of the optimal reference values and appropriate measurement timing of D-dimer testing requires further study.
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- 2021
8. Aortogenic Embolic Stroke Diagnosed by a Pathological Examination of Endovascularly Removed Thrombus: An Autopsy Report
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Genki Usui, Yoshiya Sugiura, Seiji Okubo, Teppei Morikawa, Yuji Nishi, Hirotsugu Hashimoto, Masashi Kusakabe, and Hajime Horiuchi
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Aortic arch ,Male ,medicine.medical_specialty ,Aortic Diseases ,Lumen (anatomy) ,Autopsy ,Case Report ,030204 cardiovascular system & hematology ,embolism ,Lesion ,03 medical and health sciences ,0302 clinical medicine ,Fatal Outcome ,medicine.artery ,Atrial Fibrillation ,Internal Medicine ,medicine ,Humans ,cardiovascular diseases ,Thrombus ,Embolism, Cholesterol ,Aged, 80 and over ,Cerebral infarction ,business.industry ,Endovascular Procedures ,Atrial fibrillation ,General Medicine ,aortogenic embolic stroke ,medicine.disease ,complex aortic atheroma ,cerebral infarction ,Magnetic Resonance Imaging ,Plaque, Atherosclerotic ,Cerebral Angiography ,Embolism ,Intracranial Embolism ,cardiovascular system ,030211 gastroenterology & hepatology ,pathology ,Radiology ,medicine.symptom ,atherosclerosis ,business - Abstract
Complex aortic atheroma is a high-risk factor for recurrent embolic stroke. An accurate identification of stroke etiology is clinically important; however, it can be challenging. A 91-year-old man with atrial fibrillation was diagnosed with cardioembolic stroke and treated with mechanical thrombectomy. The removed thrombus microscopically contained foamy cells, suggesting an atheroembolism. An autopsy revealed an atherosclerotic lesion with ulceration, located in the aortic arch. At the lesion, the plaque had microscopically ruptured into the lumen. We therefore concluded that the aortic atherosclerotic lesion was the embolic source. Removed thrombi should be pathologically examined even if a cardioembolic stroke is clinically suspected.
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- 2019
9. Cerebral Embolism Caused by Thrombus in the Pulmonary Vein Stump after Left Lower Lobectomy: A Case Report and Literature Review
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Genki Usui, Masahiro Yanagiya, Hajime Horiuchi, Jun Matsumoto, Tamaki Miura, Seiji Okubo, Yohei Takayama, Hirotsugu Hashimoto, Masashi Kusakabe, and Takehiro Katano
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Male ,medicine.medical_specialty ,Lung Neoplasms ,Time Factors ,Case Report ,endovascular thrombectomy ,Adenocarcinoma ,030204 cardiovascular system & hematology ,Pulmonary vein ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Cerebral embolism ,Internal Medicine ,Humans ,Medicine ,cardiovascular diseases ,Thrombus ,Lung cancer ,Stroke ,Aged ,Venous Thrombosis ,Thoracic Surgery, Video-Assisted ,business.industry ,General Medicine ,medicine.disease ,stroke ,Surgery ,lung cancer ,Intracranial Embolism ,Pulmonary Veins ,cardiovascular system ,030211 gastroenterology & hepatology ,Pulmonary Embolism ,business ,Complication - Abstract
Cerebral embolism after left upper lobectomy caused by a thrombus in the pulmonary vein stump (PVS) is a serious complication. However, it is unclear if cerebral embolism can develop after other types of lobectomy. We present a case of a 68-year-old man with cerebral embolism after left lower lobectomy with a longer PVS than normal. There were no clinically suspected sources for the thrombus except for the PVS. This thrombus seemed to have formed in the PVS. The endovascularly removed thrombus contained scattered nuclear debris around neutrophils, suggesting a physiological response caused by tissue injury.
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- 2019
10. Colon Metastasis From Microscopic Serous Carcinoma of the Fallopian Tube Fimbria Mimicking a Primary Colon Cancer
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Teppei Morikawa, Nobuyuki Matsuhashi, Genki Usui, Yasushi Harihara, Hajime Horiuchi, Hirotsugu Hashimoto, Kentaro Nakajima, Hajime Tsunoda, Masashi Kusakabe, and Yoshio Masuda
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Pathology ,medicine.medical_specialty ,Colon ,Serous carcinoma ,Colorectal cancer ,Biopsy ,Fallopian tube carcinoma ,030204 cardiovascular system & hematology ,Pathology and Forensic Medicine ,Metastasis ,Diagnosis, Differential ,03 medical and health sciences ,0302 clinical medicine ,Carcinoma ,Fallopian Tube Neoplasms ,Humans ,Medicine ,Fallopian Tubes ,Aged ,medicine.diagnostic_test ,business.industry ,Colonoscopy ,medicine.disease ,Primary tumor ,digestive system diseases ,Cystadenocarcinoma, Serous ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Colonic Neoplasms ,Female ,Surgery ,Anatomy ,Tomography, X-Ray Computed ,business ,Fallopian tube - Abstract
Metastatic diseases rarely develop in the colorectum, and diagnosing colorectal metastasis by biopsy without history of a malignant tumor or clinical information of a primary tumor is challenging. A 65-year-old woman with a 6-month history of constipation and diarrhea was admitted to our hospital and diagnosed with rectosigmoid colonic micropapillary carcinoma. Low anterior resection was performed after neoadjuvant chemotherapy. Because the lipoleiomyoma in the uterus obstructed the operator’s vision, total hysterectomy and bilateral salpingo-oophorectomy were performed. Examination of the colon and adnexa, together with immunohistochemical studies, revealed that the colonic tumor was actually serous carcinoma that had metastasized from the left fimbria of the fallopian tube. Retrospective immunohistochemical examination of the colon biopsy specimen suggested carcinoma with a Müllerian immunophenotype. When a colon biopsy reveals carcinoma with an invasive micropapillary pattern without a component of conventional tubular adenocarcinoma, immunohistochemical examination should be performed to rule out the possibility of metastasis.
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- 2019
11. Appearances of Fukushima Daiichi Nuclear Power Plant-Derived 137Cs in Coastal Waters around Japan: Results from Marine Monitoring off Nuclear Power Plants and Facilities, 1983–2016
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Takahito Ikenoue, Hyoe Takata, Naohiko Inatomi, and Masashi Kusakabe
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Fukushima Nuclear Accident ,business.industry ,General Chemistry ,010501 environmental sciences ,Nuclear power ,010403 inorganic & nuclear chemistry ,01 natural sciences ,0104 chemical sciences ,law.invention ,Fukushima daiichi ,Oceanography ,law ,Nuclear power plant ,Environmental Chemistry ,Environmental science ,Radiation monitoring ,Seawater ,Water quality ,West coast ,business ,0105 earth and related environmental sciences - Abstract
Monitoring of 137Cs in seawater in coastal areas around Japan between 1983 and 2016 yielded new insights into the sources and transport of Fukushima Daiichi Nuclear Power Plant (FDNPP)-derived 137Cs, particularly along the west coast of Japan. Before the FDNPP accident (1983–2010), the activity concentrations of 137Cs, mainly from fallout, were decreasing exponentially. Effective 137Cs half-lives in surface seawater ranged from 15.6 to 18.4 yr. After the FDNPP accident (March 2011) 137Cs activity concentrations in seawater off Fukushima and neighboring prefectures immediately increased. Since May/June 2011, 137Cs activity concentrations there have been declining, and they are now approaching preaccident levels. Along the west coast of Japan remote from FDNPP (i.e., the Japan Sea), however, radiocesium activity concentrations started increasing by 2013, with earlier (May/June 2011) increases at some sites due to airborne transport and fallout. The inventory of 137Cs in the Japan Sea (in the main body of th...
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- 2018
12. CT detection of fat retention in the bladder after partial nephrectomy
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Masashi Kusakabe, Taro Ottomo, Junichi Kazaoka, and Masaaki Akahane
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Male ,medicine.medical_specialty ,Scoring system ,Chyluria ,Urology ,medicine.medical_treatment ,Urinary Bladder ,030232 urology & nephrology ,Nephrectomy ,Asymptomatic ,030218 nuclear medicine & medical imaging ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Internal medicine ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Lipiduria ,In patient ,Retrospective Studies ,Radiological and Ultrasound Technology ,business.industry ,Gastroenterology ,Middle Aged ,Renal tumor ,Hepatology ,medicine.disease ,Lipids ,Kidney Neoplasms ,Endocrinology ,Female ,medicine.symptom ,Tomography, X-Ray Computed ,business - Abstract
This study aimed to investigate the frequency of fat retention in the bladder using postoperative computed tomography (CT) and the associated imaging or clinical findings in patients who underwent renal tumor surgery. We retrospectively reviewed postoperative CT images from 123 patients who underwent surgery for renal tumors (92 patients after partial nephrectomy and 31 after total nephrectomy). Furthermore, we evaluated preoperative tumor characteristics per an established standardized nephrometry scoring system (the R.E.N.A.L Nephrometry Score) for patients with partial nephrectomy. We also investigated whether collecting system repair occurred during surgery. Fat retention in the bladder was found in 5 patients (5.4%) after partial nephrectomy, but was not observed in any patients after total nephrectomy. No fat retention was seen immediately after partial nephrectomy (4–8 days), but occurred 2–15 months after the surgery. Subsequently, intravesical fat retention disappeared in 3 patients (8, 24, and 16 months later), and it persisted from 19–22 months after surgery in the remaining 2 patients. Collecting system repair occurred in 25 patients (27%) with partial nephrectomy. There was no statistically significant association between fat retention in the bladder and intraoperative collecting system repair (p = 0.12). The association with intravesical fat retention was not significant for either tumor size, distance to the collecting system, or the R.E.N.A.L. Nephrometry Score. Fat retention in the bladder after partial nephrectomy can be observed using CT, although it is relatively rare. It is clinically asymptomatic and disappears spontaneously in most cases.
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- 2017
13. Thrombus Reformation in the Pulmonary Vein Stump Confirmed 16 Months After Cerebral Embolism on the Day After Left Upper Lobectomy for Lung Cancer
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Masashi Kusakabe, Takehiro Katano, Jun Matsumoto, Genki Usui, Hirotsugu Hashimoto, Seiji Okubo, and Hajime Horiuchi
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Male ,medicine.medical_specialty ,Lung Neoplasms ,Time Factors ,Computed Tomography Angiography ,030204 cardiovascular system & hematology ,Pulmonary vein ,03 medical and health sciences ,0302 clinical medicine ,Recurrence ,Humans ,Medicine ,Thrombus ,Pneumonectomy ,Vein ,Lung cancer ,Aged ,Venous Thrombosis ,Lung cancer surgery ,Aspirin ,business.industry ,Rehabilitation ,Anticoagulants ,Phlebography ,Heparin ,medicine.disease ,Surgery ,Diffusion Magnetic Resonance Imaging ,medicine.anatomical_structure ,Intracranial Embolism ,Pulmonary Veins ,030220 oncology & carcinogenesis ,cardiovascular system ,Neurology (clinical) ,Cardiology and Cardiovascular Medicine ,business ,Complication ,Magnetic Resonance Angiography ,medicine.drug - Abstract
Cerebral embolism is a very serious complication after lung cancer surgery. In such cases, cerebral embolism is caused by a thrombus formed in the pulmonary vein stump. Most such cases have been reported to occur within 10 days after left upper lobectomy. The patients were treated with anticoagulation therapy to prevent the recurrence of cerebral embolism, and recurrence or thrombus reformation has not been reported to the best of our knowledge. We present a 68-year-old man with a cerebral embolism detected on the day after left upper pulmonary lobectomy for lung cancer. The patient was treated with unfractionated heparin and his neurological symptoms improved. Heparin treatment was subsequently changed to aspirin for the prevention of recurrence; however, thrombus formation in the vein stump was asymptomatically confirmed 16 months after the surgery by contrast-enhanced computed tomography. This is the first case to our knowledge of thrombus reformation in the pulmonary vein stump after a cerebral embolism associated with lung cancer surgery. In our case, anticoagulation therapy was not continued to prevent recurrence, and antiplatelet therapy was performed instead, which might be associated with the thrombus reformation.
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- 2018
14. Uterine adenomatoid tumor containing epithelioid oxyphilic cells showing prominent down-expression of HBME1 and increased Ki-67 labeling index
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Hajime Tsunoda, Masashi Kusakabe, Hironori Ninomiya, Hajime Horiuchi, Hirotsugu Hashimoto, Tamaki Miura, and Yuko Sasajima
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0301 basic medicine ,Pathology ,medicine.medical_specialty ,biology ,business.industry ,Adenomatoid tumor ,Labeling index ,General Medicine ,medicine.disease ,Pathology and Forensic Medicine ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,030220 oncology & carcinogenesis ,Ki-67 ,medicine ,biology.protein ,business - Published
- 2018
15. Arteritis and Plexiform Lesion in Intralobar Pulmonary Sequestration: The First Case With Such Two Distinct Complex Lesions Associated With Local Pulmonary Hypertension
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Hirokazu Yamaguchi, Teppei Morikawa, Noriko Hiyama, Masashi Kusakabe, Hajime Horiuchi, Jun Matsumoto, Hirotsugu Hashimoto, and Genki Usui
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Adult ,Male ,Pathology ,medicine.medical_specialty ,Intimal hyperplasia ,genetic structures ,Hypertension, Pulmonary ,030204 cardiovascular system & hematology ,Pathology and Forensic Medicine ,Pulmonary sequestration ,03 medical and health sciences ,0302 clinical medicine ,Medicine ,Humans ,Arteritis ,Bronchopulmonary Sequestration ,business.industry ,medicine.disease ,Pulmonary hypertension ,030220 oncology & carcinogenesis ,Surgery ,sense organs ,Anatomy ,business ,Plexiform lesion - Abstract
In intralobar pulmonary sequestrations, vascular changes similar to those in pulmonary hypertension (PH) are generally observed, such as intimal proliferation and plexiform lesions. However, to our knowledge, a sequestrated lung manifesting vascular changes with both arteritis and a plexiform lesion has never been reported. A 25-year-old man was diagnosed with intralobar pulmonary sequestration. Pathologically, both arteritis and a plexiform lesion were observed in the sequestrated lung. Systemic vasculitis syndrome was clinically excluded, and the pathological findings appeared to be associated with local PH. Arteritis is an extremely rare finding; only one case of arteritis associated with local PH has been reported in intralobar sequestration. In this case, the artery near the plexiform lesion had milder inflammation and fibrosis, suggesting that the arteritis formed prior to the plexiform lesion. This is the first case of arteritis and a plexiform lesion co-occurring in intralobar pulmonary sequestration associated with local PH. This case may shed light on the formation of plexiform lesions and their association with arteritis.
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- 2019
16. Intrahepatic Carcinosarcoma With Cholangiocarcinoma Elements and Prominent Bile Duct Spread
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Yuji Fujita, Yoshiya Sugiura, Hirotsugu Hashimoto, Shouichi Satou, Yasushi Harihara, Genki Usui, Masashi Kusakabe, Go Shirota, Teppei Morikawa, and Hajime Horiuchi
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Leiomyosarcoma ,Male ,Pathology ,medicine.medical_specialty ,medicine.medical_treatment ,Biopsy ,Intrahepatic bile ducts ,digestive system ,Pathology and Forensic Medicine ,Cholangiocarcinoma ,03 medical and health sciences ,0302 clinical medicine ,Carcinosarcoma ,Liver Function Tests ,medicine ,Hepatectomy ,Humans ,Aged ,Ultrasonography ,Cholangiopancreatography, Endoscopic Retrograde ,Endoscopic retrograde cholangiopancreatography ,medicine.diagnostic_test ,Bile duct ,business.industry ,Portal Vein ,gamma-Glutamyltransferase ,medicine.disease ,Embolization, Therapeutic ,Magnetic Resonance Imaging ,medicine.anatomical_structure ,Bile Ducts, Intrahepatic ,Bile Duct Neoplasms ,030220 oncology & carcinogenesis ,Asymptomatic Diseases ,030211 gastroenterology & hepatology ,Surgery ,Sarcoma ,Anatomy ,business - Abstract
Carcinosarcomas with elements of cholangiocarcinoma and sarcoma are rare and have a poor prognosis. The spreading pattern and radiological findings of these lesions remain unclear. A 74-year-old man presented with a high γ-glutamyl transferase level. Magnetic resonance imaging revealed dilation of the right intrahepatic and common bile ducts, consistent with an intraductal papillary neoplasm of the bile duct (IPNB), and diffusion-weighted imaging (DWI) indicated an area of high signal intensity in the intrahepatic bile duct. Bile duct biopsy yielded a small amount of atypical spindle cells, and the patient underwent a right hepatectomy. Microscopically, the tumor contained cholangiocarcinoma and sarcomatous components, including osteosarcoma and leiomyosarcoma, leading to a diagnosis of intrahepatic carcinosarcoma. The tumor spread primarily through the intrahepatic bile duct. An accurate radiological diagnosis of carcinosarcoma was challenging, given the apparent similarities with IPNB. The findings from DWI and pathology of a bile duct biopsy may assist with preoperative diagnosis.
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- 2019
17. Fishbone migration to bile ducts after pancreaticoduodenectomy: a case series
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Mizuho Murakami, Haruyasu Yamada, Ichiro Shirouzu, Mariko Terasaki, Hiroki Sasaki, Masashi Kusakabe, Junichi Kazaoka, and Masaaki Akahane
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Male ,medicine.medical_specialty ,Urology ,medicine.medical_treatment ,Asymptomatic ,Bone and Bones ,030218 nuclear medicine & medical imaging ,Pancreaticoduodenectomy ,03 medical and health sciences ,0302 clinical medicine ,Foreign-Body Migration ,Ct examination ,Internal medicine ,medicine ,Animals ,Humans ,Radiology, Nuclear Medicine and imaging ,Fish bone ,Aged ,Radiological and Ultrasound Technology ,Bile duct ,business.industry ,Gastroenterology ,Fishes ,Gallstones ,Hepatology ,Middle Aged ,medicine.disease ,Surgery ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Female ,Bile Ducts ,Hepatolithiasis ,medicine.symptom ,business ,Tomography, X-Ray Computed ,Follow-Up Studies - Abstract
We reviewed six cases suspected of having fish bones in the bile ducts on follow-up CT following pancreaticoduodenectomy. The period from surgery to CT examination in which fishbone migration was first suspected ranged from 282 to 1157 days with a median of 517 days. The fish bone in the bile duct disappeared in five out of six cases on subsequent CT. One case was complicated by hepatolithiasis, and the other five cases showed no biliary complications. In two cases, wandering of fish bones in the jejunal limb was observed on CT images before their migration into the bile ducts. Asymptomatic migration of fish bones to the bile ducts following pancreaticoduodenectomy is not rare, but serious complications can occasionally occur. Indications of intervention may be controversial in asymptomatic cases, but once fish bones are observed in the biliary tree or the jejunal limb, dietary instructions advising not to swallow fish bones may be a good option to prevent complications.
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- 2019
18. Enterocolic lymphocytic phlebitis with marked myointimal hyperplasia and perivenous concentric fibrosis
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Takashi Yao, Moto Nakaya, Masashi Kusakabe, Teppei Morikawa, Yasushi Harihara, Hirotsugu Hashimoto, Rihito Nagata, Hajime Horiuchi, and Genki Usui
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0301 basic medicine ,CD4-Positive T-Lymphocytes ,Male ,Abdominal pain ,Pathology ,medicine.medical_specialty ,Computed Tomography Angiography ,Biopsy ,Lumen (anatomy) ,030204 cardiovascular system & hematology ,Mesenteric Vein ,Pathology and Forensic Medicine ,Diagnosis, Differential ,03 medical and health sciences ,0302 clinical medicine ,Mesenteric Veins ,Fibrosis ,Predictive Value of Tests ,medicine ,Humans ,Enteropathy ,Arteritis ,Hyperplasia ,business.industry ,General Medicine ,Phlebography ,Middle Aged ,medicine.disease ,Immunohistochemistry ,Intestinal Diseases ,030104 developmental biology ,Treatment Outcome ,medicine.symptom ,Differential diagnosis ,Cardiology and Cardiovascular Medicine ,business ,Phlebitis ,Tunica Intima ,Rare disease - Abstract
Enterocolic lymphocytic phlebitis (ELP) is a rare enteropathy characterized by lymphocytic phlebitis of the mesenteric veins without arteritis. Idiopathic myointimal hyperplasia of mesenteric veins (IMHMV) is a rare disease similar to ELP, characterized by myointimal hyperplasia that constricts the lumen of veins, causing mucosal injury. A 62-year-old man with chief complaint of abdominal pain was treated by partial resection of the ileum after 3 months of conservative therapy. The pathologic diagnosis was ELP with prominent myointimal hyperplasia. Histologically, the lesion consisted of lymphocytic infiltration into the vein accompanied by prominent myointimal hyperplasia and perivenous concentric fibrosis, which are characteristics shared by ELP and IMHMV. The observations in this case suggest that some of ELP and IMHMV may belong to the same disease spectrum. Furthermore, perivascular concentric fibrosis was a remarkable observation that may contribute to differential diagnosis between ELP and “true” IMHMV.
- Published
- 2018
19. Solitary Pulmonary Capillary Hemangioma of Adult Cases
- Author
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Yoshio Suzuki, Kazuhiro Usui, Atsushi Kurata, Masahiko Kuroda, Hajime Horiuchi, Haruhiko Kondo, Masashi Kusakabe, Yuichi Terado, Masaaki Akahane, Masachika Fujiwara, Keisei Tachibana, Tamaki Nashiro, Hiroshi Kamma, Hirotsugu Hashimoto, Jun Matsumoto, and Kei Hara
- Subjects
Adult ,Male ,CD31 ,Pathology ,medicine.medical_specialty ,Lung Neoplasms ,Lumen (anatomy) ,Autopsy ,030204 cardiovascular system & hematology ,Pathology and Forensic Medicine ,Hemangioma ,03 medical and health sciences ,0302 clinical medicine ,Biomarkers, Tumor ,medicine ,Frozen Sections ,Humans ,Hemangioma, Capillary ,Pneumonectomy ,Retrospective Studies ,Solitary pulmonary nodule ,Frozen section procedure ,business.industry ,Capillary hemangioma ,Middle Aged ,medicine.disease ,Treatment Outcome ,Positron-Emission Tomography ,030220 oncology & carcinogenesis ,Female ,Surgery ,Anatomy ,Tomography, X-Ray Computed ,business ,Follow-Up Studies ,Rare disease - Abstract
Solitary pulmonary capillary hemangioma (SPCH) is a rare disease, first described about autopsy cases in 2000 and about surgically resected cases in 2006. To date, only 9 surgically resected cases have been published in English. Here, we report 7 original cases with surgery (median age, 54 y; 4 females, 2 never-smokers). All patients were asymptomatic, and all nodules were detected by computed tomography (CT). The median (range) size of nodule was 11 (8 to 16) mm. Six of 7 cases showed the part-solid nodule appearance and 1 showed pure ground-glass nodule appearance in CT findings. The growth speed was very slow. No abnormal uptake of fluorine-18 fluorodeoxyglucose was observed in systemic positron-emission CT in all 3 cases we examined. No patients died from SPCH. Histologically, SPCH manifested as a solitary lesion composed of densely proliferating and dilated capillaries without cytologic atypia within the alveolar septa. In addition, capillaries of SPCH spread into the vascular lumen and involved the walls of bronchioles with protrusion into the lumen. Immunohistochemically, capillaries of SPCH uniformly expressed endothelial markers, such as CD31, CD34, and Factor VIII; and α-smooth muscle actin positive cells were also observed. To be accurately diagnosed, especially in intraoperative frozen sections, SPCH should be conceived as an entity that presents as a solitary nodule in CT. We propose that SPCH is an unrecognized benign capillary proliferative disease.
- Published
- 2016
20. The Contribution of Sources to the Sustained Elevated Inventory of 137Cs in Offshore Waters East of Japan after the Fukushima Dai-ichi Nuclear Power Station Accident
- Author
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Masashi Kusakabe, Hyoe Takata, Naohiko Inatomi, Kazuyuki Hasegawa, and Takahito Ikenoue
- Subjects
Hydrology ,Water Pollutants, Radioactive ,010504 meteorology & atmospheric sciences ,Meteorology ,business.industry ,General Chemistry ,010501 environmental sciences ,Nuclear power ,01 natural sciences ,Japan ,Cesium Radioisotopes ,Radiation Monitoring ,Fukushima Nuclear Accident ,Environmental Chemistry ,Environmental science ,Submarine pipeline ,Water volume ,business ,0105 earth and related environmental sciences - Abstract
We have evaluated the contribution of sources of (137)Cs to the inventory of radiocesium in waters (surface area: 6160 km(2), water volume: 753 km(3)) off Fukushima Prefecture and neighboring prefectures from May 2011 to February 2015. A time-series of the inventory of (137)Cs in the offshore waters revealed a clearly decreasing trend from May 2011 (283.4 TBq) to February 2015 (1.89 TBq). The (137)Cs inventory about four years after the accident was approximately twice the background inventory of 1.1 TBq. The magnitudes of the (137)Cs influxes from sources into offshore waters for periods of 182-183 days were estimated from the first period (1 October 2011 to 31 March 2012: 15.3 TBq) to the last period (1 October 2014 to 31 March 2015: 0.41 TBq). We assumed that three sources contributed (137)Cs: continuous direct discharge from the Fukushima Dai-ichi Nuclear Power Station (FNPS) even after the massive discharge in late March 2011, desorption/dissolution from sediments, and fluvial input. Quantification of these sources indicated that the direct discharge from the FNPS is the principal source of (137)Cs to maintain the relatively high inventory in the offshore area.
- Published
- 2016
21. Necrotizing arteritis occurring in an intralobar pulmonary sequestration of a patient without systemic vasculitis syndrome
- Author
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Hirotsugu Hashimoto, Yoshio Suzuki, Atsushi Kurata, Hajime Horiuchi, Jun Matsumoto, Masaaki Nagano, Masahiko Kuroda, Masashi Kusakabe, Tamaki Nashiro, and Kei Hara
- Subjects
Adult ,Pathology ,medicine.medical_specialty ,030204 cardiovascular system & hematology ,Pathology and Forensic Medicine ,Pulmonary sequestration ,03 medical and health sciences ,0302 clinical medicine ,Necrotizing Vasculitis ,medicine ,Humans ,Bronchopulmonary Sequestration ,Lung ,Polyarteritis nodosa ,business.industry ,Systemic Vasculitis ,General Medicine ,medicine.disease ,Pulmonary hypertension ,Polyarteritis Nodosa ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Female ,Intralobar sequestration ,Cardiology and Cardiovascular Medicine ,Vasculitis ,business ,Systemic vasculitis - Abstract
Necrotizing arteritis is a complex lesion of pulmonary hypertension, as are plexiform lesions, and is classically recognized as grade 6 in the Heath and Edwards grading scheme for hypertensive pulmonary vascular disease. The vascular changes observed in intralobar pulmonary sequestration have been reported to be similar to those observed in pulmonary hypertension, such as plexiform lesions. However, necrotizing arteritis occurring in an intralobar sequestration of a patient without systemic vasculitis syndrome has never been reported to our knowledge. Here, we report a case of a 38-year-old woman with pulmonary sequestration detected on a medical checkup. She was treated with surgery, and subsequent pathological analyses revealed necrotizing vasculitis in her sequestrated lung. We suspected systemic vasculitis syndromes, such as Takayasu arteritis, polyarteritis nodosa, and antineutrophil cytoplasmic antibody-associated vasculitis. However, physical and blood examination did not show any other abnormalities, and hence, she did not have systemic vasculitis syndrome. Immunohistochemical analyses of the resected specimen showed that inflammatory cells of the arteries were mainly composed of T lymphocytes. T-lymphocytic inflammation with little neutrophil and histiocyte infiltration may be a pathological feature of necrotizing arteritis observed in pulmonary sequestration. This is the first case to our knowledge of necrotizing arteritis in an intralobar pulmonary sequestration of a patient without systemic vasculitis syndrome.
- Published
- 2016
22. Atherosclerosis of aberrant arteries from the left gastric artery into the right intralobar pulmonary sequestration complicated by mycobacterial epithelioid cell granuloma
- Author
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Masahiro Yanagiya, Hirotsugu Hashimoto, Sayaka Ohara, Jun Matsumoto, Atsushi Kurata, Yoshio Suzuki, Hajime Horiuchi, and Masashi Kusakabe
- Subjects
Male ,Pathology ,medicine.medical_specialty ,Left gastric artery ,030204 cardiovascular system & hematology ,Pulmonary Artery ,Pathology and Forensic Medicine ,Pulmonary sequestration ,03 medical and health sciences ,0302 clinical medicine ,medicine.artery ,medicine ,Humans ,Bronchopulmonary Sequestration ,Aged ,Mycobacterium avium-intracellulare Infection ,Lung ,Granuloma ,business.industry ,Epithelioid Cells ,General Medicine ,medicine.disease ,Atherosclerosis ,Pulmonary hypertension ,Diaphragm (structural system) ,Pneumonia ,medicine.anatomical_structure ,030220 oncology & carcinogenesis ,Pulmonary artery ,Cardiology and Cardiovascular Medicine ,business ,Epithelioid cell - Abstract
Vascular changes observed in intralobar pulmonary sequestration (PS) have been reported to be similar to those observed in pulmonary hypertension (PH). However, atherosclerosis in the pulmonary artery, which is one of the characteristic arterial changes of PH, has scarcely been reported in PS. Here, we report this unique manifestation in a 66-year-old man, in whom an intralobar PS fed by an aberrant artery branching from the left gastric artery had been identified 10 years earlier, and who was diagnosed with pneumonia after having symptoms of fever and cough. He was treated by lobectomy of the lower lobe of his right lung. Subsequently, a culture test of the fluid from the sequestrated lung was performed, which identified Mycobacterium avium. Subsequent pathological examination of the sequestrated lung demonstrated multiple epithelioid cell granulomas. Furthermore, atherosclerosis of the aberrant artery was also found, which may be associated with his advanced age. This is an extremely rare case of right intralobar PS supplied by aberrant artery with atherosclerosis originating from left gastric artery passing over the diaphragm.
- Published
- 2016
23. A case of solitary pulmonary capillary hemangioma indicating true gross appearance
- Author
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Yoshio Suzuki, Hirotsugu Hashimoto, Hajime Horiuchi, Masashi Kusakabe, Masahiro Yanagiya, Jun Matsumoto, and Genki Usui
- Subjects
0301 basic medicine ,Pathology ,medicine.medical_specialty ,business.industry ,Capillary hemangioma ,General Medicine ,medicine.disease ,Pathology and Forensic Medicine ,Hemangioma ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,Text mining ,030220 oncology & carcinogenesis ,medicine ,business - Published
- 2017
24. Latest Fundamental Technology for Radiological Sciences
- Author
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Masashi Kusakabe and Yoshiyuki Shirakawa
- Subjects
Engineering ,medicine.medical_specialty ,Nuclear Energy and Engineering ,business.industry ,Radiological weapon ,medicine ,Medical physics ,business - Published
- 2011
25. An estrogen receptor-positive locally aggressive smooth muscle neoplasm of the transverse colon
- Author
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Yoshiya Sugiura, Yasushi Harihara, Kazuteru Watanabe, Hirotsugu Hashimoto, Masashi Kusakabe, Eiji Sakai, Teppei Morikawa, Genki Usui, and Hajime Horiuchi
- Subjects
0301 basic medicine ,Gastrointestinal tract ,medicine.medical_specialty ,Abdominal pain ,Smooth Muscle Neoplasm ,medicine.diagnostic_test ,business.industry ,Transverse colon ,Colonoscopy ,General Medicine ,Lesion ,03 medical and health sciences ,030104 developmental biology ,0302 clinical medicine ,030220 oncology & carcinogenesis ,medicine ,Adjuvant therapy ,Transverse Colectomy ,Radiology ,medicine.symptom ,business - Abstract
Rationale: Extrauterine leiomyomas (LMs) in women are often positive for the estrogen receptor (ER); however, almost all extrauterine leiomyosarcomas (LMSs) are negative for ER. Invasive smooth muscle neoplasms (SMNs) of the gastrointestinal tract walls are very rare and those ER statuses have not been well studied. Patient concerns: A 48-year-old woman presented to our hospital with a 10 years history of recurrent severe abdominal pain and diarrhea lasting about an hour, with frequency of about twice per year. She was clinically diagnosed with a submucosal tumor (SMT) of the transverse colon and underwent a partial transverse colectomy. Diagnosis: A colonoscopy revealed a 30-mm SMT in the transverse colon. A contrast abdominal computed tomography detected a 21-mm mass with significant late phase enhancement in the transverse colon and the lesion was clinically diagnosed as an SMT. Post-operative pathology confirmed a diagnosis of ER-positive locally aggressive SMN. Interventions: The patient underwent laparoscopic partial transverse colectomy. Outcomes: The patient received no adjuvant therapy postoperatively. The patient has remained disease-free without recurrence 13 months after the surgery. Lessons: This is the first case of an ER-positive invasive SMN in the gastrointestinal tract. It highlights the difficulty in classifying some gastrointestinal SMNs as either LMs or LMSs and the importance of ER status in SMNs.
- Published
- 2018
26. Endoscopic bronchial occlusion for postoperative persistent bronchopleural fistula with computed tomography fluoroscopy guidance and virtual bronchoscopic navigation
- Author
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Yoko Matsumoto, Ryutaro Furukawa, Jun Matsumoto, Masashi Kusakabe, Masahiro Yanagiya, Kazuhiro Usui, Masaaki Nagano, and Sayaka Ohara
- Subjects
Male ,medicine.medical_specialty ,Lung Neoplasms ,medicine.medical_treatment ,Bronchopleural fistula ,Adenocarcinoma ,030204 cardiovascular system & hematology ,bronchial occlusion ,03 medical and health sciences ,Pneumonectomy ,Postoperative Complications ,0302 clinical medicine ,Bronchoscopy ,Occlusion ,medicine ,Humans ,Fluoroscopy ,Clinical Case Report ,Empyema ,bronchopleural fistula ,medicine.diagnostic_test ,business.industry ,virtual bronchoscopic navigation ,Pneumonia ,General Medicine ,Middle Aged ,Pleural Diseases ,medicine.disease ,Bronchial Fistula ,computed tomography fluoroscopy ,030228 respiratory system ,Cardiothoracic surgery ,Radiology ,Tomography, X-Ray Computed ,business ,Research Article - Abstract
Rationale: The development of postoperative bronchopleural fistula (BPF) remains a challenge in thoracic surgery. We herein report a case of BPF successfully treated with endoscopic bronchial occlusion under computed tomography (CT) fluoroscopy and virtual bronchoscopic navigation (VBN). Patient concerns: A 63-year-old man underwent right upper lobectomy with concomitant S6a subsegmentectomy for lung adenocarcinoma. On postoperative day 24, he complained of shaking chills with high fever. Diagnoses: BPF with subsequent pneumonia and empyema. Interventions: Despite aggressive surgical interventions for the BPF, air leakage persisted postoperatively. On days 26 and 34 after the final operation, endobronchial occlusions were performed under CT fluoroscopy and VBN. Outcomes: The air leaks greatly decreased and the patient was discharged. Lessons: CT fluoroscopy and VBN can be useful techniques for endobronchial occlusion in the treatment of BPF.
- Published
- 2018
27. Outcomes of thoracoscopic management of secondary pneumothorax in patients with COPD and interstitial pulmonary fibrosis
- Author
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Tomohiro Murakawa, Takeshi Fukami, Jun Nakajima, Shinichi Takamoto, Masashi Kusakabe, and Yukihiro Yoshida
- Subjects
Male ,medicine.medical_specialty ,Pulmonary Fibrosis ,Blood Loss, Surgical ,Pulmonary Disease, Chronic Obstructive ,Pleural disease ,Postoperative Complications ,Pulmonary fibrosis ,medicine ,Thoracoscopy ,Humans ,Aged ,Retrospective Studies ,COPD ,Lung ,Rupture, Spontaneous ,medicine.diagnostic_test ,business.industry ,Respiratory disease ,Pneumothorax ,Middle Aged ,respiratory system ,medicine.disease ,humanities ,respiratory tract diseases ,Surgery ,body regions ,Treatment Outcome ,surgical procedures, operative ,medicine.anatomical_structure ,Female ,Lung Diseases, Interstitial ,business ,Abdominal surgery - Abstract
We retrospectively analyzed the outcomes of surgical treatment for patients with secondary spontaneous pneumothorax.Among consecutive patients with secondary pneumothorax who had undergone surgical treatment from 1993 to 2007, those with chronic obstructive pulmonary diseases (COPD) and those with diffuse pulmonary fibrotic diseases (PFD) were collected and divided into two groups (COPD group and PFD group). Postoperative morbidity and mortality were analyzed between the two groups.We enrolled 72 patients (73 surgeries) as the COPD group and 14 patients (14 surgeries) as the PFD group. All of the surgical treatments were initiated through thoracoscopy. Mean age of the patients at surgery was significantly older in the COPD group compared with the PFD group. The surgeries in the COPD group were significantly longer than those in the PFD group. The bleeding volume during surgery in the COPD group was higher than that in the PFD group. Thoracoscopy was more frequently replaced with open thoracotomy in the PFD group (21.4%) than in the COPD group (2.7%; p = 0.0019). In the PFD group, two patients died from postoperative exacerbation of the pulmonary fibrosis and one died from the sepsis caused by the empyema. One patient in the COPD group died of pneumonia. The postoperative mortality rate was significantly higher in the PFD group (21.4%) than in the COPD group (1.4%; p = 0.001).Favorable results were obtained in patients in the COPD group. However, the postoperative mortality rate in the PFD group was significantly higher than those in the COPD group. This increase in the mortality rate in the PFD group was mainly caused by postoperative exacerbation of pulmonary fibrotic diseases.
- Published
- 2009
28. Video-assisted thoracic surgery lobectomy preserves more latissimus dorsi muscle than conventional surgery
- Author
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Yukihiro Yoshida, Hiroshi Ohtsu, Masashi Kusakabe, Tomohiro Murakawa, Shinichi Takamoto, Jun Nakajima, Takahiro Karasaki, and Takeshi Fukami
- Subjects
Male ,Pulmonary and Respiratory Medicine ,medicine.medical_specialty ,Lung Neoplasms ,Time Factors ,medicine.medical_treatment ,Preoperative care ,Scapula ,Carcinoma, Non-Small-Cell Lung ,Laparotomy ,medicine ,Humans ,Thoracotomy ,Stage (cooking) ,Muscle, Skeletal ,Pneumonectomy ,Thoracic Wall ,Lung cancer ,Aged ,Retrospective Studies ,Thoracic Surgery, Video-Assisted ,business.industry ,Latissimus dorsi muscle ,nutritional and metabolic diseases ,Middle Aged ,medicine.disease ,Surgery ,Muscular Atrophy ,Treatment Outcome ,Cardiothoracic surgery ,Lymph Node Excision ,Female ,Radiology ,Tomography, X-Ray Computed ,Cardiology and Cardiovascular Medicine ,business - Abstract
Video-assisted thoracic surgery (VATS) lobectomy for early lung cancer has become technically feasible. We sought to determine if VATS preserved chest wall muscle postoperatively better than thoracotomy. Consecutive patients who underwent lobectomy between 2004 and 2006 for clinical Stage IA non-small cell lung cancer through VATS (VATS group) or posterolateral thoracotomy (PLT group) at our institution were eligible for the study. The cross-sectional areas of bilateral latissimus dorsi muscle (LDM) at the lower end of the scapula were obtained by computed tomography preoperatively and one year after surgery. These were quantified with image analysis by two researchers in a blinded manner. Fourteen patients in the VATS group (mean age, 68 years; 8 men, 6 women) and 24 patients in the PLT group (mean age, 62 years; 14 men, 10 women) were assessed. Postoperative/preoperative ratios of the LDM cross-section areas on the surgical side were 89+/-20% (Mean+/-S.D.) in the VATS group and 57+/-16% in the PLT group (P
- Published
- 2008
29. A study on Dynamics of Ocean Observation Platform with Wave Power Devise
- Author
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Masashi Kusakabe, Tetsuro Ikebuchi, Masahiko Nakamura, Wataru Koterayama, and Naoyuki Takatsu
- Subjects
Engineering ,Ocean observations ,business.industry ,Mooring system ,Electric power ,business ,Air chamber ,Mooring ,Wave power ,Marine engineering - Abstract
Model experiments and numerical simulations on motions and mooring tensions of an ocean observation platform were made for the design of the mooring system and platform. The platform is under development for the study of green house effects and is planned to be moored in very rough sea area of 5000m depth. The performance of wave power device, which is installed in the platform to supply the electric power for instruments used in the chemical, biological and physical measurements, is also discussed based on pressure variations generated in the air chamber of the platform model.In general, results of numerical simulations showed good agreement with those of experiments, though a few points needing improvement were discussed.
- Published
- 2000
30. Percutaneous transluminal renal angioplasty with stenting for stenotic venous bypass grafts: report of two cases
- Author
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Tetsuro Miyata, Masaaki Akahane, Hiroki Sasaki, Jiro Sato, Masashi Kusakabe, and Kuni Ohtomo
- Subjects
medicine.medical_specialty ,Multidisciplinary ,Percutaneous ,Case Study ,Bypass grafting ,business.industry ,medicine.medical_treatment ,Angioplasty ,Renal artery stenosis ,medicine.disease ,Surgery ,surgical procedures, operative ,Renal angioplasty ,Renal artery ,medicine.artery ,High pressure ,medicine ,Stents ,Venous grafts ,Venous bypass ,Radiology ,business - Abstract
Cases of percutaneous transluminal renal angioplasty for renal artery stenosis are increasing. However, percutaneous transluminal renal angioplasty with stenting for stenotic venous bypass grafts has never been reported. Herein, the authors describe two cases of percutaneous transluminal renal angioplasty with stenting for a stenotic venous bypass graft. The patients in both cases had undergone bypass grafting using autologous saphenous veins, which were anastomosed directly to their abdominal aortas. We successfully conducted percutaneous transluminal renal angioplasty with stenting. One of the keys for technical success is an appropriate selection of guiding catheter compatible with postoperative nonanatomical vasculature, and the other is relatively high pressure dilation for venous stenosis.
- Published
- 2013
31. Invasive lymphangioma of the lung manifesting as a large pulmonary mass with hemoptysis: report of a case
- Author
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Akiteru Goto, Tomohiro Murakawa, Takeshi Fukami, Jun Nakajima, Shinichi Takamoto, and Masashi Kusakabe
- Subjects
Pathology ,medicine.medical_specialty ,Hemoptysis ,Lung Neoplasms ,government.form_of_government ,Antibodies, Monoclonal, Murine-Derived ,Fibrosis ,Parenchyma ,Lymphangioma ,Biomarkers, Tumor ,Medicine ,Humans ,Child ,Lymphangiomatosis ,Lung ,business.industry ,Antibodies, Monoclonal ,General Medicine ,respiratory system ,medicine.disease ,Immunohistochemistry ,Lymphatic Endothelium ,Lymphatic system ,medicine.anatomical_structure ,government ,Surgery ,Female ,business ,Pulmonary Mass ,Tomography, X-Ray Computed - Abstract
Solitary lymphangioma of the lung is rare. We report a case of invasive lymphangioma of the lung, diagnosed in a 9-year-old girl who presented with intractable hemoptysis and a large pulmonary mass, 10 cm in diameter. We performed left lower lobectomy and lingular segmentectomy to remove the mass completely and the patient has been well for 3 years since. Pathologically, the mass was partly polycystic and partly solid. Irregular and dilated vascular and lymphatic vessels, as well as fibrosis of the interstitium, were spreading into the adjacent lung parenchyma, demonstrating their invasive nature. A new monoclonal antibody, D2-40, which reacts with lymphatic endothelium, proved useful for establishing the pathological diagnosis. We suggest that these pathological findings might be consistent with the intermediate type of localized lymphangioma of the lung and diffuse lymphangiomatosis.
- Published
- 2006
32. A case of 11mm-sized flat elevated type colon carcinoma invading muscularis propria
- Author
-
Takamichi Yamane, Shinji Hirai, Masashi Kusakabe, Soichi Hotta, Kazumitsu Ueda, Toshiro Kamoshida, Yuji Oka, Tatsuro Shimokama, Minoru Okumura, Munekatsu Sato, and Yasunori Otashiro
- Subjects
Oncology ,Pathology ,medicine.medical_specialty ,Colon carcinoma ,business.industry ,Mechanical Engineering ,Internal medicine ,Energy Engineering and Power Technology ,Medicine ,Management Science and Operations Research ,business - Published
- 2003
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