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Background Gastric mucosal lesion (GML) is the initiating pathological process in many refractory gastric diseases. And moxibustion is an increasingly popular alternative therapy that prevents and treats diseases. However, there are few published reports about developing pathology of GML and therapeutic mechanism of moxibustion treatment on GML. In this study, we investigated pathology of GML and therapeutic mechanism of moxibustion treatment on GML. Methods The male Sprague-Dawley (SD) rats were induced by intragastric administration of 75% ethanol after fasting for 24 h and treated by moxibustion at Zusanli (ST36) and Liangmen (ST21) for 1 day, 4 days or 7 days. Then we applied 1H NMR-based metabolomics to dynamic analysis of metabolic profiles in biological samples (stomach, cerebral cortex and medulla). And the conventional histopathological examinations as well as metabolic pathways assays were also performed. Results Moxibustion intervention showed a beneficial effect on GML by modulating comprehensive metabolic alterations caused by GML, including energy metabolism, membrane metabolism, cellular active and neurotransmitters function. Conclusions Moxibustion can effectively treat gastric mucosal damage and effectively regulate the concentration of some related differential metabolites to maintain the stability of the metabolic pathway.

In Traditional Chinese Medicine (TCM), moxibustion had been used for thousands of years. Many clinical case reports and scientific studies had proved that moxibustion had a good effect in treating acute gastric ulcer (AGU). Some studies had shown that the relative content and species of bacteria in the intestinal would be changed when gastric mucosal injury happened. However, there was little research on the effect of intestinal microbiome with AGU rats that were treating by moxibustion. This study is aimed at analyzing the effect of fecal microbiome in rats with AGU by the 16S rDNA sequencing technology. Male SD rats were established by orally feeding once with 70% ethanol at 4 ml/kg except the control group, then treated by moxibustion in the stomach meridian group (“Liangmen,” “Zusanli”) and the gallbladder meridian group (“Riyue,” “Yanglingquan”) for 5 days. The 16S rDNA sequencing technology analysis of feces combined with histopathological methods and molecular biological detection methods was used to evaluate the therapeutic mechanism of moxibustion on AGU. AGU brought cause changes in the number and species of intestinal bacteria. Moxibustion on stomach meridian group could reduce the area of gastric mucosal injury and regulate the relative content of GAS and EGF. Moreover, moxibustion on the stomach meridian group could increase the relative content and species of beneficial bacteria in the intestine of rats with AGU. The relative abundance of intestinal probiotics was significantly upregulated in Alphaproteobacteria, Actinomycetales, and Bacillales. In addition, moxibustion might promote the repair of gastric mucosal injury by increasing the number and species of beneficial bacteria in the intestine.

Gastric ulcer (GU), a common digestive disease, has a high incidence and seriously endangers health of human. According to the previous studies, it has been proved that electroacupuncture at acupoints of stomach meridian had a good effect on GU. However, there are few published studies on metabolic response in gastric ulcer (GU) rats with electroacupuncture treatment. Herein, we observed the metabolic profiles in biological samples (stomach, liver, and kidney) of GU rats with electroacupuncture treatment by 1H NMR metabolomics combined with pathological examination. The male SD rats were induced by intragastric administration of 70% ethanol after fasting for 24 hours and treated by electroacupuncture at Zusanli (ST36) and Liangmen (ST21) for 1 day, 4 days, or 7 days, respectively. And the conventional histopathological examinations as well as metabolic pathways assays were also performed. We found that GU rats were basically cured after electroacupuncture treatment for 4 days and had a complete recovery after electroacupuncture treatment for 7 days by being modulated comprehensive metabolic changes, involved in the function of neurotransmitters, energy metabolism, cells metabolism, antioxidation, tissue repairing, and other metabolic pathways. These findings may be helpful to facilitate the mechanism elucidating of electroacupuncture treatment on GU.

In this paper it constructs a phase shift to control zero-voltage-switching of high frequency inverter spot welding power supply topology structure. Through testing the former vice edge current, the system realizes the closed loop control. In this paper, it shows the working condition of main circuit modal. The experimental results proved the advantages of the topological structure.

It is the China production pattern that beef cattle bred north and then were transported down south for growing up. With the lack of transport vehicles for beef cattle, they have to suffer much from rugged environments during the long-distance transportation. Jarring and scaring vehicles, shortages of drinking and other such unfavorable factors make cattle in vehicles develop the symptom of physiological stress, so-called transport stress syndrome of beef cattle (TSSBC), and even die, causing huge economic losses to animal husbandry enterprises. This paper raises a goose-neck double-deck enclosed semi-trailer with the length of 13m special for beef cattle based on investigates on animal transportation technologies domestic and abroad. Fans and blinds were set in both sides of the wagon box to air the room, while power-driven scaling tarpaulin on the top functions to protect beef cattle inside from sunshine and rain. And more, innovative design of the vertical lifting and falling hydraulic tailboard make it easy to achieve independently loading and unloading of beef cattle free from more help.

The technology of soft-switching can improve stability ,reliability and efficiency of the inverting spot welding power supply .In this paper ,a new kind of topology of zero-voltage switching spot welding power supply is proposed ,which is auxiliary circuit in paralleling with the lagging lag ,so it can afford auxiliary current of soft switch .With the relationship between circuit state of every working mode of main circuit and main circuit parameters in new topology ,the ability of searching optimal overall situation of ACA is used to optimize circuit parameters ,and it turns out to confirm the advantage of this topology .

Social innovation is an emerging perspective of radical innovation transiting our society towards sustainability. Design, dealing with innovation issues, is supposed to play an important role in promoting it. Two workshops in Italy and China are organized as a pilot exploration with inter-cultural perspectives in service design for grassroots social innovations. Results show that service design can be a viable approach to intervene social innovations. Service design experiences are concluded in terms of local context, problem definition, targeting group and new business mode.

This paper presents the design and implementation of a photovoltaic inverter equipment monitoring system based on bluetooth technology on Android platform, including the inverter detector and the Android smart-phone. The inverter detector used STM32F103ZET6 as the main control chip. The real-time data received from inverter equipment were stored in AT45DB161 Flash chip and transmitted to the smart-phone via the bluetooth wireless link. Then, the smart-phone processed the received information and displayed it in graph view. Industrial applications show that the monitoring system has the advantages of high stability and performance, and the communication range reaches to about 100 meters in outdoor space.