1. Effect of non-surgical periodontal treatment on three salivary adipokines in diabetic patients with periodontitis
- Author
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Narges Ziaei, Mari Ataee, Shima Golmohammadi, Mehran Mesgari Abbasi, and Farnoosh Ardalani
- Subjects
medicine.medical_specialty ,Periodontal treatment ,Saliva ,type 2 diabetes mellitus ,Adipokine ,Gastroenterology ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,visfatin ,progranulin ,Medicine ,Chemerin ,General Dentistry ,adipokines ,periodontitis ,030304 developmental biology ,Periodontitis ,0303 health sciences ,biology ,business.industry ,human chemerin protein ,Type 2 Diabetes Mellitus ,030206 dentistry ,medicine.disease ,Chronic periodontitis ,Clinical trial ,lcsh:RK1-715 ,non-surgical periodontal debridement ,lcsh:Dentistry ,biology.protein ,Original Article ,business - Abstract
Background. This study investigated the effect of non-surgical periodontal treatment on clinical indices and salivary levels of visfatin, chemerin, and progranulin in diabetic patients with periodontitis. Methods. This interventional clinical trial was performed on 20 patients with type II diabetes mellitus (T2DM) with moderate to severe chronic periodontitis (periodontitis stages II or III according to the new classification of periodontal diseases). Clinical indices, including gingival index (GI), probing pocket depth (PPD), clinical attachment level (CAL) and plaque index (PI), were recorded and visfatin, chemerin, and progranulin adipokines levels were also measured in unstimulated saliva by ELISA technique at baseline and twelve weeks after non-surgical periodontal treatment. Results. GI dropped from 1.92±0.27 to 0.71±0.14 after the intervention (P
- Published
- 2020