1. Anatomic and procedural associations of transcatheter heart valve displacement following Evolut R implantation
- Author
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Marco Ancona, Azeem Latib, Ozan M. Demir, Vittorio Romano, Fabrizio Monaco, Satoru Mitomo, Antonio Colombo, Damiano Regazzoli, Nicola Buzzatti, Daisuke Hachinohe, Paolo Del Sole, Francesco Giannini, Pier Pasquale Leone, Alessandra Laricchia, Antonio Mangieri, Eustachio Agricola, Matteo Montorfano, Hachinohe, Daisuke, Latib, Azeem, Laricchia, Alessandra, Demir, Ozan M., Agricola, Eustachio, Romano, Vittorio, Del Sole, Paolo Alberto, Leone, Pier Pasquale, Ancona, Marco B., Mangieri, Antonio, Regazzoli, Damiano, Giannini, Francesco, Mitomo, Satoru, Monaco, Fabrizio, Buzzatti, Nicola, Montorfano, Matteo, and Colombo, Antonio
- Subjects
Male ,displacement ,Radiology, Nuclear Medicine and Imaging ,medicine.medical_specialty ,Time Factors ,Transcatheter aortic ,TAVR ,030204 cardiovascular system & hematology ,Prosthesis Design ,Severity of Illness Index ,Transcatheter Aortic Valve Replacement ,TAVI ,03 medical and health sciences ,Postoperative Complications ,0302 clinical medicine ,Risk Factors ,Upward displacement ,Internal medicine ,medicine.artery ,Linear regression ,Ascending aorta ,medicine ,Humans ,Radiology, Nuclear Medicine and imaging ,Displacement (orthopedic surgery) ,030212 general & internal medicine ,Heart valve ,transcatheter aortic valve implantation ,Aged ,Retrospective Studies ,Aged, 80 and over ,Bioprosthesis ,business.industry ,Aortic Valve Stenosis ,General Medicine ,aortic stenosi ,Confidence interval ,Treatment Outcome ,medicine.anatomical_structure ,Aortic Valve ,Heart Valve Prosthesis ,Cardiology ,Female ,self-expanding ,Multiple linear regression analysis ,Cardiology and Cardiovascular Medicine ,business - Abstract
Objectives This study aimed to predict the displacement of self-expanding transcatheter heart valves (THV) during final deployment. Background Accurate device positioning during transcatheter aortic valve implantation (TAVI) is crucial for optimal results. Methods At our institution, 103 patients who underwent transfemoral TAVI with Evolut R were retrospectively identified. Multiple linear regression models were created, and a predictor equation was built to quantify the factors that may affect THV behavior. Results Multiple linear regression analysis for THV displacement on the left coronary cusp (LCC) identified the angle between the THV and the ascending aorta (ATA), predilation, and less operator experience as independent predictors of upward displacement, whereas estimated glomerular filtration rate (eGFR) was inversely related with THV behavior (95% confidence interval: 0.219 to 0.340, 0.447 to 2.092, 0.165 to 1.757, and -0.053 to -0.011, respectively). Predictors of THV displacement on the noncoronary cusp side could not be identified using this model. Conclusions The ATA at the point of recapture, predilation, and less operator experience were independent predictors of upward displacement of THV on the LCC side. eGFR was an independent predictor of THV downward displacement on the LCC side. Of them, the ATA was the strongest predictor. Physicians may need to adjust this angle adequately before deployment to achieve the appropriate position.
- Published
- 2018