1. Seroprevalence of hepatitis B and hepatitis C among blood donors in Sierra Leone: A multi-year retrospective study
- Author
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Francesco Di Gennaro, Giampietro Pellizzer, Francesca Tognon, Molly F. Franke, Sahr Gevao, Annelies W. Mesman, Marta Lado, Giovanni Putoto, Katrina Hann, Stephen Sevalie, Emily Bearse, Yusupha Dibba, Claudia Marotta, Mohamed Sheku, Fenella Beynon, Joseph Gassimu, and John Martin Sesay
- Subjects
0301 basic medicine ,Microbiology (medical) ,Adult ,Male ,medicine.medical_specialty ,Hepatitis B virus ,Epidemiology ,Hepatitis C virus ,030106 microbiology ,Population ,Seroprevalence ,Hepacivirus ,medicine.disease_cause ,Blood donors ,Sierra Leone ,Viral hepatitis ,Female ,Hepatitis B ,Hepatitis C ,Humans ,Prevalence ,Retrospective Studies ,Seroepidemiologic Studies ,Transfusion Reaction ,Vaccination ,Young Adult ,Blood Donors ,Sierra leone ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,0302 clinical medicine ,Internal medicine ,medicine ,lcsh:RC109-216 ,030212 general & internal medicine ,education ,Hepatitis ,education.field_of_study ,business.industry ,General Medicine ,medicine.disease ,Infectious Diseases ,business - Abstract
Objectives: In Sierra Leone, very little data are available on hepatitis B virus (HBV) and hepatitis C virus (HCV) prevalence. Blood donor screening permits estimation of the prevalence of transfusion transmissible infections in a general open population. We analyzed blood donor data in Sierra Leone to estimate national viral hepatitis prevalence and identify risk factors for hepatitis infection among the donor population. Methods: We conducted a retrospective data analysis in five government hospitals. We collected HBV and HCV screening results, donor demographics, and donation type (family replacement or voluntary donor; first-time or repeat). Univariate and multivariate analyses were performed to determine associations between infections and socio-demographic factors. Results: The number of donors screened was 29,713. The overall prevalence was: 10.8% (3200) for HBV and 1.2% (357) for HCV. HBV infection was most strongly associated with male sex (p
- Published
- 2020