1. Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety assessments
- Author
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Peter Tanuseputro, Mina Tadrous, Maria E. Sundaram, Andrew Calzavara, Susan E. Bronskill, Sarah Wilson, Siyi He, Sharifa Nasreen, Hannah Chung, Kumanan Wilson, Sarah A Buchan, and Jeffrey C. Kwong
- Subjects
Vaccine safety ,Baseline rates ,COVID-19 Vaccines ,Coronavirus disease 2019 (COVID-19) ,Short Communication ,COVID-19 vaccine safety ,Context (language use) ,01 natural sciences ,Long-term care ,03 medical and health sciences ,0302 clinical medicine ,NH, nursing home ,Pandemic ,Humans ,Medicine ,030212 general & internal medicine ,Mortality ,0101 mathematics ,Pandemics ,COVID-19, coronavirus disease 2019 ,Ontario ,General Veterinary ,General Immunology and Microbiology ,SARS-CoV-2 ,business.industry ,010102 general mathematics ,Public Health, Environmental and Occupational Health ,COVID-19 ,Emergency department ,Nursing Homes ,3. Good health ,Hospitalization ,Vaccination ,Infectious Diseases ,Molecular Medicine ,ED, emergency department ,Emergency Service, Hospital ,business ,Nursing homes ,Demography - Abstract
Background Nursing home (NH) residents are prioritized for COVID-19 vaccination. We report monthly mortality, hospitalizations, and emergency department (ED) visit incidence rates (IRs) during 2010–2020 to provide context for COVID-19 vaccine safety assessments. Methods We observed outcomes among all NH residents in Ontario using administrative databases. IRs were calculated by month, sex, and age group. Comparisons between months were assessed using one-sample t-tests; comparisons by age and sex were assessed using chi-squared tests. Results From 2010 to 2019, there were 83,453 (SD: 652.4) NH residents per month, with an average of 2.3 (SD: 0.28) deaths, 3.1 (SD: 0.16) hospitalizations, and 3.6 (SD: 0.17) ED visits per 100 residents per month. From March to December 2020, mortality IRs were increased, but hospitalization and ED visit IRs were reduced (p Conclusion We identified consistent monthly mortality, hospitalization, and ED visit IRs during 2010–2019. Marked differences in these rates were observed during 2020, coinciding with the COVID-19 pandemic.
- Published
- 2021