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BACKGROUND Sarcopenia and cachexia are two predictors of adverse clinical outcomes, but they are partly overlapping. We aimed to compare the characteristics and prognostic value of cachexia and sarcopenia in patients after gastrectomy. METHODS From 2014 to 2019, a total of 1215 gastric cancer patients were enrolled. Cachexia and sarcopenia were diagnosed according to the most recent consensus definitions. Baseline characteristics and clinical outcomes were compared between the two groups. Risk factors of survival were evaluated by Cox regression analysis. RESULTS Of all patients, 26.5% were diagnosed with cachexia and 19.8% were diagnosed with sarcopenia. Sarcopenia was more prevalent in elderly patients, while cachexia was prone to occur in patients with TMN stage III. Survival curves showed that sarcopenia had adverse effects in patients with TMN stage I and II-III, while cachexia was only associated with poor survival at stages II-III. For the entire cohort, both cachexia and sarcopenia were adverse factors for prognosis. However, for stage I patients, sarcopenia was an independent predictor for overall survival (OS) (HR = 4.939, P < 0.001) and disease-free survival (DFS) (HR = 4.256, P < 0.001), but not cachexia; for stage II-III patients, cachexia was an independent predictor for OS (HR = 1.538, P < 0.001) and DFS (HR = 1.473, P = 0.001), but not sarcopenia. CONCLUSIONS Sarcopenia and cachexia have different clinical characteristics and prognostic values. For patients with early stage gastric cancer, detection for sarcopenia was more meaningful than cachexia. However, the prognostic significance of cachexia exceeded sarcopenia in advanced cancer.

Summary Background The present study aims to investigate the prognostic value of Global Leadership Initiative in Malnutrition (GLIM)-defined malnutrition in overweight patients who underwent gastrectomy for gastric cancer, and to explore whether the addition of muscle quality, strength and gait speed could improve the predictive power for postoperative outcomes. Methods Overweight patients (body mass index (BMI) ≥23 kg/m2) who underwent radical gastrectomy for gastric cancer were included in this study. Malnutrition was diagnosed using the two-step approach following the GLIM criteria. Skeletal muscle mass and quality was assessed using computed tomography (CT) determined skeletal muscle index (SMI) and skeletal muscle density (SMD), respectively. Hand-grip strength and 6-m gait speed were measured before surgery. Results A total of 587 overweight patients were included, in which 262 patients were identified as having obesity (BMI ≥25 kg/m2). The prevalence of malnutrition was 11.9% and 10.7% for overweight and obese patients, respectively. GLIM-defined malnutrition alone was not predictive for postoperative complications in overweight patients. The addition of low gait speed or muscle quality to GLIM-defined malnutrition led to a significant predictive value for postoperative complications. Low gait speed plus GLIM-defined malnutrition remained significant in the multivariate analysis. GLIM-defined malnutrition was predictive for overall survival (OS) and disease-free survival (DFS). Addition of low gait speed to GLIM-defined malnutrition increased the hazard ratio (HR) for the prediction of OS and DFS (univariate analysis: 2.880 vs. 2.238 for OS, 2.410 vs. 1.937 for DFS; multivariate analysis: 2.836 vs. 1.841 for OS, 2.433 vs. 1.634 for DFS). Addition of low hand-grip strength to GLIM-defined malnutrition led to a higher HR for the prediction of OS (2.144 vs. 1.841) in the multivariate analysis. Conclusion Muscle quality, strength and gait speed added prognostic value to GLIM-defined malnutrition for the prediction of postoperative complications and/or survival in overweight patients who underwent radical gastrectomy for gastric cancer, especially gait speed, which could be incorporated into nutritional assessment protocols.

Truncated Painleve expansion method is used to solve the fifth order potential Bogoyavlenskii-Schiff equation. New exact solutions with lower-dimensional arbitrary functions are obtained. By using the symbolic computation software Maple, some typical examples with specific parameters are exhibited, which have various physical features.

Few studies have comprehensively analyzed the correlations among body composition parameters, muscle strength, and physical performance, as well as the influence of these factors on the postoperative complications and survival after radical gastrectomy for gastric cancer.A prospective study was conducted including patients who underwent radical gastrectomy for gastric cancer from August 2014 to June 2019. Skeletal muscle index (SMI), skeletal muscle density (SMD), visceral fat area (VFA), subcutaneous fat area (SFA) was obtained by measurement of preoperative computed tomography (CT) images. Grip strength and 6-m gait speed were measured to assess muscle strength and physical performance before surgery.There was a positive correlation between SMI and SMD, as well as between SFA and VFA. SMD negatively correlated with SFA and VFA. SMI had a positive correlation with VFA, but showed minimal correlation with SFA and visceral to subcutaneous fat ratio (VSR). Grip strength and gait speed were both positively correlated with SMI and SMD, but showed minimal correlation with SFA, VFA and VSR. SMI and grip strength independently predicted postoperative complications, rather than SMD or gait speed. Whereas SMD and gait speed had independent predictive value for overall survival (OS) and/or disease-free survival (DFS), rather than SMI or grip strength. VSR independently predicted postoperative complications, rather than VFA or SFA alone. Low SFA was an independent risk factor for OS and DFS. High VFA was associated with worse survival in overweight patients (body mass index, BMI ≥25), but was associated with better survival in non-overweight patients (BMI25). High SFA did not significantly influence survival in overweight patients, but was associated with better survival in non-overweight patients.There is an extensive and complex correlation among body composition parameters, grip strength, and gait speed in patients with operable gastric cancer. A comprehensive analysis of these parameters has significant predictive value for postoperative complications and survival.

Aim: Breast cancer is one of the leading causes of cancer-associated death. This work aimed to explore the expression, function, and mechanism of circ_0000526 on the progression of breast cancer. Materials and Methods: The expressions of circ_0000526, miR-492, and suppressor of cytokine signaling 2 (SOCS2) in breast cancer samples were measured using quantitative real-time polymerase chain reaction. The correlation between pathological indexes of patients and the expression of circ_0000526 was also analyzed. Human breast cancer cell lines MCF-7 and MDA-MB-231 were applied to investigate the associated mechanism. Cell counting kit-8 assays were used to assess the effect of circ_0000526 on proliferation, and together with the wound healing assay, transwell assay was conducted to detect the effects of circ_0000526 on migration and invasion. Furthermore, luciferase reporter assay was used to verify the targeting relationship between miR-492 and circ_0000526. In addition, Western blot was performed to detect the regulatory effects of circ_0000526 on SOCS2. Results: Circ_0000526 expression in breast cancer samples was downregulated, which was correlated with unfavorable pathological indexes. It significantly inhibited the proliferation and metastasis of breast cancer cells, and facilitated apoptosis. The overexpression of circ_0000526 remarkably inhibited the expression of miR-492 by sponging it, and in turn promoted the expression of SOCS2. Conclusions: Circ_0000526 served as a tumor suppressor, which could function as the sponge of miR-492, an oncogenic microRNA, in breast cancer, and enhance the expression of tumor suppressor SOCS2 indirectly.

Based on the demonstration projects from the database of CPPPC, using social network analysis and econometric methods, this paper examines the between enterprises in the networks, and analy...

Objectives We investigated whether measurement of muscle quantity/quality has additional predictive value for postoperative complications and long-term survival after gastrectomy for gastric cancer in patients with probable sarcopenia, as defined by the new European Working Group on Sarcopenia in Older People 2 consensus. Methods We conducted a prospective study of patients who underwent a radical gastrectomy for gastric cancer between August 2014 and June 2019. Muscle strength was measured using a handgrip dynamometer. Computed tomography images at the third lumbar vertebra level were used to assess muscle quantity and quality by the measuring cross-sectional muscle area and mean muscle attenuation, respectively. Probable sarcopenia was defined by low muscle strength. Sarcopenia was diagnosed by additional low muscle quantity or quality. Clinical outcomes were obtained by prospective data collection and follow up. Results Probable sarcopenia was identified in 419 patients, including 285 patients with sarcopenia. Patients with sarcopenia had a higher incidence of postoperative complications, higher costs, longer length of postoperative hospital stay, and worse overall survival (OS) and disease-free survival (DFS) compared with patients with low muscle strength only. The multivariate logistic analysis showed that sarcopenia and hypoproteinemia were independent risk factors for postoperative complications in patients with probable sarcopenia. Moreover, multivariate Cox analyses showed that sarcopenia remained an independent risk factor for OS and DFS in patients with probable sarcopenia. Conclusions The measurement of muscle quantity/quality has additional predictive value for postoperative complications, OS, and DFS after gastrectomy for gastric cancer in patients with probable sarcopenia.

The wide use of polymers to enhance oil recovery can make pumping and rejecting oilfield produced water difficult because of the high viscosity of the treated water. To deal with this problem, this study proposed an electrocoagulation method that is time saving, highly efficient, and easy to apply. A Box–Behnken design coupled with the response surface methodology (RSM) was used to construct a model of the electrocoagulation process that considers three key variables: current density, inter-electrode gap, and operation time. The optimized operational conditions were obtained using second-order polynomial models; they were a current density of 45.6 mA/cm2, an inter-electrode of 3.2 cm, and an operation time of 22.8 min. The results under these conditions were a viscosity reduction of 90.9% and a chemical oxygen demand (COD) reduction of 74.9%. These data strongly correlated with the predicted values of the RSM models. Based on the single and interactive effect analysis, it showed that viscosity and...

In this paper, the mechanism of radio frequency (RF) causing fire and explosion directly and indirectly was recommended, studies of RF risks in flammable and explosive environments were summarized, some problems in RF risk researches recently were discussed, study prospects of RF risks in flammable and explosive environments were analyzed. The fact that the mechanisms and conditions of RF igniting combustible gases should be researched by more deeply theories and technological means, and that RF security standards should be laid down and a complete and precise RF security assessment system should be established in flammable and explosive environments was put forward.

This paper analyzes the influence of ChangJiu High-speed Railway on power quality. Compared with the traditional AC-DC electric locomotive, AC-DC-AC electric locomotive has been widely used in High-speed Railway which harmonic content decreased significantly, power factor also improved. Based on the RTDS simulation, voltage sags have not been caused when electric locomotive is starting.

Against the State Grid Corporation of integrated demonstration project pilot project Gong qing smart grid demonstration project 1.5MWp rooftop PV projects access, combined with the actual situation, combined with the ETAP software features of advanced power quality analysis , first proposed using ETAP software for power quality analysis and evaluation of two kinds of access solutions , to establish the model flow calculation example, three different nodes of the short circuit calculation and harmonic calculations for the power sector access system designed to provide a reference.

With the rapid grow of the volume of data and internet application, as an efficient and promising infrastructure, data center has been widely deployed .data center provide a variety of perform for network services, applications such as video stream, cloud compute and so on. All this services and applications call for volume, compute, bandwidth, and latency. Existing data centers lacks enough flexible so they provide poor support in QOS, deployability, manageability, and defense when facing attacks. Virtualized data centers are a good solution to these problems. Compared to existing data centers, virtualized data centers do better in resource utilization, scalability, and flexibility.

Next generation Internet network mobility management is an urgent and challenging research area. With the development of wireless technology, mobile network research gets more and more attention. NEMO protocol is presented based on mobile IPv6, it not only ensures the continuity of communication when subnet move, but also makes the mobility transparently for the subnet. NEMO technology application can more adapt to the development requirements of the next generation mobile communication network. This paper first introduced the NEMO technology and the existing NEMO routing optimization scheme. Then analyzed and compared the performance of each schemes in the data path and package message overhead.

For the technical requirements of a domestic enterprise to develop a new generation of self-loading container truck products, this paper creatively puts forward a set of suitable reduction standards for special structure. Based on ANSYS and Visual Studio 2008 platform, the parametric modeling and automatic analysis of side loader container structure are achieved independently. Several operating conditions, such as stacking, self-loading and unloading etc. can be analyzed rapidly and automatically. The research achievement can be not only used for the conceptual design stage of forward design process, but also applied in the modification of the original structure, thus effectively shortening the product design cycle, reducing design cost, providing useful guidance for independent research of domestic enterprise.

The function generator is the classic analog adder circuit, either independently or as an intermediate for its links embedded in complex circuits, have a very wide range of applications. Function generator can be used as the signal source to produce for research, teaching, experimental signals for different purposes such as how to make it more accurate and stable signal generation, has been widespread concern and research; Similarly, construction work adder circuit commonly used as a module, accurate input-output relationship is also very worth exploring. Therefore, this paper, on both a profound theoretical analysis, based on the modeling and simulation through the more figurative exposition of both operating characteristics, application to increase its theoretical basis.

For the simulation of wind turbine, the wind speed is extremely important parameters and indicators to measure the output power of the unit is the wind load. Therefore, in the airflow dynamics and simulation of wind loads before establishing an accurate wind speed model is crucial. At present, the application for wind turbines COMSOL fan, fan blades and wind load simulation field, the extremely important wind speed model is not perfect, most of the research is confined to a single constant wind speed, wind speed virtually ignored the magnitude and direction of change, on changes over time and space at the same time is one of the few studies of wind, so find a way to accurately describe the range of wind speeds, and can be combined well with COMSOL method can greatly improve the aerodynamic performance of wind turbines the overall level of .

In recent years,the ad hoc network has been paid extensive attention due to its characteristics of non-center and self-organization.Firstly this paper introduces three typical routing protocols AODV,DSDV,DSR,and the principles of them; then,adopts the NS2 simulation platform to simulate the performance of end-to-end delay,routing overhead and packet delivery ratio by changing the number of nodes and the paused time of nodes.Finally,by comparing the simulating results, the comparison conclusion is provided.

Electric power industry is related to people's livelihood, economic development, an important foundation for national construction industry. With the deepening of our country comprehensive construction, the demand has increased rapidly, at the same time also have higher requirements for quality of power supply. From the previous electricity use can be gradually increased to cannot accept a power outage, to the power grid voltage waveform, harmonic, frequency and so on each index has a clear requirement, countries have introduced related national standard specification. This aspect shows a gradually increase in the standardization of industrialization in China, on the other hand also puts forward higher demands on distribution power supply departments. One of the goals of the grid is to reduce the failure rate, improve the reliability of power supply. And power grid failure and is the highest percentage of short circuit fault, and the single-phase earth fault and occupy the vast majority of proportion, it is necessary to in-depth analysis of the formation mechanism of single-phase earth fault and damage, so as to find the related protection and remedial measures.

Since the wireless mesh network topology dynamics and the radio channels instable, the design of wireless mesh network routing protocol become one of the key factors to determine the performance. This paper mainly studied the existing several kinds of typical three-layer mesh network routing protocol (DSDV and AODV), aimed at the defects of three-layer routing limited to the network topology changes, the paper proposed a network model based on two-layer routing. Forwarding the packet, establishing and maintaining the communication links are accomplished on the Mac layer. Simulation tests showed that two-layer routing has a big improvement on the efficiency of packet forwarding, and it effectively reduced the routing overhead and end-to-end delay simultaneously.

Inverter technology as the key part of using new energy technology, can be very effective to new energy sources such as solar, battery and fuel cell energy conversion of ac electrical energy transform into ac power, and can be connected to the grid. Therefore, the inverter technology has an extremely important statue in modern society.

A new method to store the harmonic energy is proposed, by offering harmonic energy to DC load directly by combining the diode’s one-way electric conduction theory with the first-harmonic resonance theory. Using the PSCAD/EMTDC software to simulate the project in single phase and three phases. And it turn out that the theory is feasible.

Principles of traditional Boost PFC circuit are introduced. Based on average current control, a large signal model is obtained and turned into small signal model carrying constant load. And current regulator and voltage regulator are designed accordingly. Directing at strong non-linear characteristics of the circuit, this paper adopts double average method to analyze its low frequency stability. This converter can achieve high power factor in wide range of input and load power and simulation result shows that power factor is above 0.99.

DC voltage, input voltage and current need testing for control circuit of general PFC circuit that makes circuit complex and high cost. And using of sensors decreases the reliability of circuit. Hence, simulation analysis of single phase APFC without DC voltage sensor is present in this paper.

Model creating and simulation of switching power circuit in this paper was accomplished with PSpice A/D module in CAPTURE CIS. Components in library or created could be used for circuit model. After setting the parameters, simulation could be processed and the result is shown in PROBE. For simulation analysis, this paper creates models for every part of the circuit firstly and then the whole.

In recent years, as the SVC device have also been used for DC ice melting system, the installment is still on the rise, it is necessary to study the loss situation. This paper firstly analyzed the theory of the loss of its each part of the device, and then finished a simulation based on the PSCAD software. We hope the research can give some value guidance on SVC assembled for the power grid.

This paper studies and analyzes the BER performance of the OFDM system, and completes the system simulation on this basis, measures and calculates the BER through the SNR, the Doppler effect and the Short Guard Interval. During the simulation, we use BPSK, QPSK and 16PSK modulation techniques, and choose the Gaussian white noise channel. Using SNR, Doppler effect and Short Guard Interval effects to OFDM signal can improve the system performance.

This paper emphasizes the wireless relaying performance analysis in interference environment. We will analyze the main performance metrics such as outage and error probability of the communication system in interference environment, and will make some simulation to demonstrate the result of theory analysis. In relay transmission system, either two relaying or multiple relaying, its basic principles are based on the two relaying system. In this paper, the wireless relay system performance in the interference environment will be analyzed and simulated on the basis of previous studies.

The processing of target image using image processing technology, can realize the non-contact online detecting circuit board, thus greatly improve the detection efficiency, reducing the defective rate. This paper provides the detection system based on the methods of pre-processing the standard circuit board image and the circuit board image to be detected, two value segmentation, morphological image processing, image registration and poor shadow detection processing, among them ,image registration is the key. In order to improve the processing speed to achieve real-time processing, image registration using rapid processing algorithm. Analysis of the experimental results, the method can detect the defects on the circuit board to be detected accurately, and can achieve the automatic real-time detection purposes.

Through the analyzing of the color, motion, parallax and the degree of clarity in scene-all the elements presented on the 2D video, People can produce 3D video smoothly. The paper introduces a kind of pick-up algorithm of depth map, the method of combining the abstraction of motion in depth based on the block matching and the abstraction of background in depth on the basis of background subtraction. The extracted map can be applied to the video conversion technology of "2D to 3D".

In the modern digital communication system, inter-symbol interference (ISI) caused by the imperfectness of the channel is a major factor that degrades the performance of communication. In order to decrease the influence of ISI and improve communication quality, people usually use equalization technology. Generally, channel response is changing over time, so the adaptive equalizer is necessary. This paper firstly introduced the theoretical foundation and realization method of the adaptive equalization system. Then discuss the LMS algorithm. Finally, the SIMULINK tool is used to build a communication system. The set of simulation results by observing the eye diagrams of the signals before and after equalization have validated the equalization effect.

This paper proposes a three-phase inspection policy model based on a three-stage failure process for a single unit system. Different from existing works which usually assume unique inspection interval, the three-phase inspection policy allows the inspection policy to change according to the identified state of the unit. The possible renewal scenarios are considered based on which the cost model is proposed. Numerical example is presented, and the results clearly reveal the advantage of the three-phase inspection policy over the unique interval inspection.

Internal Model Control (IMC) is widely used in Network Control System (NCS) with its strong robustness and simple parameter adjustment. But the accurate dynamic inversion of the IMC model is not easy to find out. To solve this problem, an improved Internal Model Controller is designed with a PID controller and feedback loop, then the Particle Swarm Optimization (PSO) is used to optimize all the parameters of the improved controller. At last, simulation results show that the improved Internal Model Controller can maintain the system stability and the performance of the step response is extremely great in terms of rapidity and anti-interference ability, compared with the classic internal model controller, which enables NCS to achieve a better control effect.

With the development of automobile industry, more and more people need automotive information. Meanwhile, there’s a great deal of network information which makes people gather information hard. To make people acquire the automotive information more efficiently, an Automotive News Push System is desperately needed. A distributed focused crawler is proposed for the system to assure that the information is accurate and timely. In this paper, distributed system framework and webpage classification are analyzed. Experimental results show that the frameworkare effective, the accuracy and efficiency of crawling are both improved.

Anti-climber is one of the most important passive safety devices for railway vehicles. Based on the non-linear finite element method, properties of the anti-climber with different vertical offsets are simulated by the software LS-DYNA. The force-displacement curve is mainly analyzed, and the energy absorbed by the anti-climber is also calculated in order to assess the properties. At last, an improvement method with a cross structure inside the anti-climber is designed for the offset problem and is proved effective by the simulation.

The data transmission scheme between a transmission control protocol/internet protocol (TCP/IP) network port and a serial port based on an ARM embedded system is introduced in the paper. The data transmission between a personal computer (PC) and remote equipment through an Internet is realized. The structure of a hardware platform is simply introduced, the cutting and transplant of operating system, the communication program design of the network port and the serial port and the cross compiling between the two ports are introduced in detail. The AT91SAM9261 chip of ATMEL Corporation is employed as the embedded board of a kernel processor. The Redhat9 Linux operating system is employed as a software development platform, an ARM-Linux operating system is employed as a program operation platform and the kernel version is Linux-2.6.2. The C program is used and an ARM-Linux-GNU tool chain is used for the cross compiling. The experimental result proves that the real-time, parallel full duplex data transmission between the network port and the serial port is realized by the scheme provided in the paper.

In this paper, a simulation method based on joining non-linear finite element and multi-body dynamics is developed to solve the energy configuration of crashworthy metro train. The relationships of non-linear springs which describe characters of forces-deformation for energy absorption during crash event are obtained by using non-linear Finite Element Analysis (FEA) techniques. Then they are used in simulation for collision of two metro train sets with multi-body dynamics. Compare to the different energy absorption configuration, the results of impact force, deformation, velocity and acceleration are analyzed to assess the passive safety of whole train set. The results indicate that the joining simulation strategy is feasible and effective. It can be used to improve the metro train crashworthiness design by optimizing the energy absorption configuration.

In order to maximize knowledge sharing and reuse in networked manufacturing process and improve the rapidity and reliability of decision-making, a knowledge-integration model and its implementation methods are proposed in this paper. First, the requirement for knowledge integration in networked manufacturing is analyzed. On this basis, a knowledge-integration model is built, and then three key technologies are studied, namely knowledge representation and organization based on ontology, knowledge correlation analysis based on complex network and knowledge supply based on decision-making context. This model provides an effective way to realize the optimum distribution of knowledge in networked manufacturing process and to improve the efficiency of decision-making process.

Ellipse expression is difficult to be found directly. And the detail form which is important for electrical field analysis has not been described. The arrangement mode of lines affect electrical field significantly. Hence, simulation of triangular and horizon arrangement are proceeded in this paper. The terms include rotation track, rotation direction and initial phase angle.

Recently, SVC and STATCOM have gotten a very quick development because they can be triggered dynamically and have feedback module so that they can inspects the vacancy of the Var and compensate it quickly and dynamically. In this paper, the stabilization of voltage in substation based on SVC in TCR and FC mode has been discussed.

Wind speed of the time-varying bring many security hidden danger to the operation of the wind turbine, especially under the condition of the wind speed is too low or the wind speed is too large, wind turbine control device can make the wind machine stopped running, at this time on the stability of power grid and significant influence on the distribution of electric power system. Therefore, based on the simulation platform of PSCAD/EMTDC software was carried out on the wind turbine when suddenly stop running of power system modeling and simulation, research on power system transient changes at this moment.

Chromatic dispersion and nonlinearity effect are the two important factors affecting the optical pulse which propagates in the optical fiber. The former makes the pulse broaden, the latter mainly broaden pulse spectrum. Therefore, the linear and nonlinear dispersive propagation and control of optical pulses in the fiber has always been an important research topic of concern. In this paper, Starting from the nonlinear Schrodinger equation of the optical pulse and neglecting the chromatic dispersion, under the situation of chirp and chirp-free Gaussian pulse, we analytical analyzed, calculated and simulated the frequency chirp, pulse broadening factor and waveform of the Gaussian optical pulses in dispersion fiber. And numerical studied the waveform evolution of chirp-free super-Gaussian optical pulse with distance, analyzed the influence of optical pulse propagation by dispersion in different shapes and different initial chirp.

The OFDM system modulates signal by using a plurality of spectrum aliasing orthogonal sub-carriers, so it is extremely sensitive to carrier frequency offset, and any tiny frequency offset may destroy the orthogonality of the sub-carriers, thereby seriously affecting the performance of the system. So carrier frequency offset is the primary problem for the OFDM technology, and in recent years it has also become a focus for researchers. Accurate frequency synchronization is the precondition for the OFDM system to work properly. The main purpose of this paper is to seek a more reliable and viable carrier frequency offset estimation algorithm on the results of previous studies.

PID control is one of the earliest control strategy and till has the most widely use in the industrial process at the present. The PID parameter tuning and optimizing decide what the control performance of the control system can achieve. PID parameter tuning is the core content in control system design. In this paper, aiming at the complexity of PID parameter tuning process, the critical ratio method was optimized and propose a simple and effective method of tuning PID parameters. By simulation, this method turn out to be simple and effective, good real-time performance.

The main purpose of this paper is to solve the yawing problem of a single point mooring catamaran which designed for some special offshore operations. Dynamic characteristics of mooring system had been analyzed with the effect of wind, wave and current in early research. The results show that the yawing motion would be occurred for that system and can not be avoided without external control methods. These results are supported by sea tests of the real catamaran. Then, an azimuth thruster, set aft the ship, is used for a simple dynamic positioning (DP) system of the catamaran. The system is not a complete DP system because only one freedom can be controlled for the horizontal plane motions of the catamaran. The yawing angle is selected as control variable to meet the design requirement. The thrust is perpendicular to the longitudinal axis of the ship and can provide a maximizing yaw motion for DP system. Proportional-derivative control law is applied and the feedback variables can be obtained by global positioning system in further practices. The control effectiveness is validated by numerical results and comparisons with the non-controlled situations.

The purpose of this paper is to solve the positioning problem of a double body working ship. Dynamic characteristics of mooring system are analyzed with the effect of wind, wave and current. According to the dynamic equations of the system in the horizontal plane, longitudinal force coefficient, lateral force coefficient and yawing moment coefficient are obtained by towing test. The wind lord, wave load, current load and chain force can be calculated by empirical formulas. The motions of a mooring system are simulated in MATLAB. The results show that yawing motion would be occurred for the mooring system with single anchor at one point. The motions of the system have similar forms under the same amplitude of external loads. The results are agreed well with the observation data from documents about this relation. It is also can be point out that single point mooring system has poor stability and can not control the motion accurately. Thus dynamic positioning/mooring system should be developed for anchored working ships. This research in this paper provides the theoretical support and the analysis foundation for the further studies.

In the industry, effectively improve the speed of production management and troubleshooting information quickly and efficiently share representatives do have better productivity, and thus may bring more cash flow. Except for the Storage and Cloud Computing concept of Cloud Platform, this paper provided new point about sharing issue. A good share resources available way to multinationals, can successfully improve production efficiency and reduce equipment downtime.

Introduction Deep venous thrombosis (DVT) is one of the common peripheral vascular diseases. The recruitment and migration of bone marrow-derived endothelial progenitor cells (EPCs) to the sites of venous thrombus are necessary in the process of thrombus organization and recanalization. Our objective was to investigate the functional role of miR-150 in rat EPCs and its potential application in deep venous thrombosis. Materials and Methods Rat EPCs were cultured and transfected with miR-150 mimics and inhibitor. Wound healing assay, transwell migration assay and matrigel tube formation assay were performed to elucidate the effect of miR-150 of rat EPCs. Lentiviral construct expressing miR-150 was transfected into EPCs and the EPCs were injected to rat models of DVT. The rats were sacrificed on the day of 7 and 14 after the transplantation and the histological study was performed. Luciferase reporter assay and Western blot were performed to evaluate rat miR-150 regulates the expression of c-Myb. Results MiR-150 significantly promoted the migration and tube formation ability of EPCs in vitro and enhanced EPCs’ homing, organization and resolution ability in vivo. Overexpression of miR-150 significantly reduced the protein level of c-Myb and repressed the activity of a luciferase reporter containing both of the two predicted miR-150 binding sites in c-Myb 3’-UTR, indicating that c-Myb may be a miR-150 target gene. Conclusion MiR-150 enhanced the migration, tube formation, homing, thrombus recanalization and resolution ability of rat EPCs. Restoring miR-150 in EPCs revealed potential application in DVT therapy.