Author: "ZHANG, Xiao" / Topic: business - Searchworks@Jio Institute Digital Library Search Results

747 results on '"ZHANG, Xiao"'

1. Experimental observation of the vascular self-healing hollow fibers containing rejuvenator states in bitumen

Author: Su, Jun-Feng, Zhang, Xiao-Long, Guo, Yan-Dong, Wang, Xian-Feng, Li, Feng-Ling, Fang, Yuan, Ding, Zhu, and Han, Ning-Xu
Subjects: Bituminous materials -- Research -- Properties, Fibers -- Research, Fluorine compounds, Tomography, Microscopy, Electron microscopy, CAT scans, Polyvinylidene fluoride, Business, Construction and materials industries
Abstract: ABSTRACT Hollow fiber containing rejuvenator is a promising smart material for vascular self-healing bituminous materials of pavement. The objective of this work was to experimentally observe the states of self-healing [...]
Published: 2019
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2. China's ETS pilots: Program design, industry risk, and long-term investment

Author: Zhang Xiao-Ling, Qi Shaozhou, Yan Ya-Xue, and Kai Li
Subjects: Finance, H1-99, Atmospheric Science, Global and Planetary Change, China, business.industry, Allowance (money), Differential (mechanical device), Certification, Benchmarking, Management, Monitoring, Policy and Law, Investment (macroeconomics), Profit (economics), Social sciences (General), Long-term investment, Meteorology. Climatology, Emissions trading, Program Design Language, Program design, QC851-999, business, Industry risk, ETS
Abstract: The emissions trading scheme (ETS) is considered an effective policy tool for achieving emission reductions. At present, China’s ETS pilots have completed several compliance periods and provided rich experience for a national ETS. Taking advantage of the variations in the regional ETS pilots across regions and sectors and over time, this study used a difference-in-difference-in-differences (DDD) model to examine the effects of ETS pilots and differential program design on industry risk and the impacts of risk on future investment horizon. First, we found that the ETS pilots significantly increase profit variability (total risk) in China’s industry; that is, ETS induces greater uncertainty in the covered sectors. In terms of industry heterogeneity, non-electricity sectors (specifically ferrous metal) engage in higher levels of risk taking. Second, the influence of such program features as the allowance allocation (total amounts and approaches), China Certification Emission Reduction (CCER) trading volumes, and penalties are heterogeneous. Finally, during the period around the treatment, industry risk can significantly encourage longer rather than shorter investment. In particular, the punishment mechanism and benchmarking allocation play a positive role in regulating the risk‒investment relationship.
Published: 2022

3. Investigating the electrothermal self-healing bituminous composite material using microcapsules containing rejuvenator with graphene/organic hybrid structure shells

Author: Zhang, Xiao-Long, Guo, Yan-Dong, Su, Jun-Feng, Han, Shan, Wang, Ying-Yuan, and Tan, Yi-Qiu
Subjects: Bituminous materials -- Investigations -- Electric properties -- Research -- Properties, Graphene -- Investigations -- Electric properties -- Research, Electrical conductivity -- Investigations -- Electric properties -- Analysis, Graphite -- Investigations -- Electric properties -- Research, Business, Construction and materials industries
Abstract: Illustration of electrothermal self-healing bituminous material using microcapsules containing rejuvenator with graphene/organic hybrid structure shells, (a-c) mechanism of self-healing bituminous material using microcapsules containing rejuvenator without graphene, (d-f) mechanism of [...]
Published: 2018
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4. Novel vascular self-nourishing and self-healing hollow fibers containing oily rejuvenator for bitumen

Author: Zhang, Xiao-Long, Su, Jun-Feng, Guo, Yan-Dong, Wang, Xin-Yu, Fang, Yuan, Ding, Zhu, and Han, Ning-Xu
Subjects: Bituminous materials -- Mechanical properties -- Analysis, Fibers -- Mechanical properties -- Analysis, Polyvinylidene fluoride -- Analysis, Business, Construction and materials industries
Abstract: ABSTRACT The aim of this work was to prepare and characterize a novel vascular self-nourishing and self-healing hollow fiber containing oily rejuvenator for aged bitumen. The hollow fibers containing oily [...]
Published: 2018
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5. Effect of calcium aluminate cement on water resistance and high-temperature resistance of magnesium-potassium phosphate cement

Author: Zhang, Xiao, Li, Guoxin, Niu, Mengdie, and Song, Zhanping
Subjects: Drag (Fluid dynamics) -- Chemical properties -- Analysis, Potassium phosphates -- Chemical properties -- Analysis, Cements (Building materials) -- Chemical properties -- Mechanical properties -- Analysis, Business, Construction and materials industries
Abstract: ABSTRACT The effects of calcium aluminate cement (CAC) on strength, water resistance and high-temperature resistance of magnesium-potassium phosphate cement (MKPC) was investigated. The CAC substituted with 20, 30 and 40 [...]
Published: 2018
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6. Deformation Mechanism and Control Ttechnology of Surrounding Rock of the Roadway in a Steep Coal seam

Author: Tu Hongsheng, Huang Chang-wen, Guo Chen-ye, Liu Songyong, Zhang Xiao-bo, and You Zu-feng
Subjects: Hydrogeology, Computer simulation, business.industry, Coal mining, Soil Science, Geology, Deformation (meteorology), Geotechnical Engineering and Engineering Geology, Displacement (vector), Mining engineering, Architecture, Coal, Point (geometry), business, Roof
Abstract: This study combined theoretical analysis, numerical simulation via FLAC3D software, innovative design, and field measurements for establishing the mechanical model of the stressed coal rock and deriving the deformation and failure characteristics of the roadway in a steep coal seam. The No. 49# steep-seam working face of the Xintie Coal Mine, China, was used as a case study with asymmetrical force characteristics of the mining roadway. The roof and the right side of the roadway under study were identified as the main deformation and failure zones in the roadway of the steep working face. Next, a rigid/flexible support method that fully enclosed two sides and the roof was designed and substantiated. It comprised three pre-stressed resin anchor cables combined with anchor rods, iron net, and steel bands for the roadway roof support; besides, three anchor rods were combined with iron net and steel bands for supporting the right side of the roadway. A novel self-mobile forepoling hydraulic support group with side and roof support functions was developed. A grouting reinforcement was applied to the crushed coal rock in the geologic anomaly zone to enhance the overall performance. Finally, the measured displacements of the roof and the floor were found to exceed those of the roadway sides. The whole advancing process of the steep-seam working face was conditionally split into three segments, namely, Segment I with no mining effect (at a distance over 50 m from the working face), Segment II with a mining effect (at 20 ~ 50 m from the working face), and Segment III with a strong mining effect (20 m in front of the working face). The displacement at the deepest point on the roof was the maximal, followed by that in the range of 0 ~ 1.5 m, which made it possible to reduce the number of anchors on the left side of the roadway required by the conventional symmetric support mode. The performed field measurements proved that the proposed asymmetric support mode ensured the mining safety requirements of the working face under normal mining operations, being more cost-effective and efficient than the conventional symmetric one.
Published: 2021
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7. In-situ experimental investigation of the influence of structure characteristics on subway-induced building vibrations

Author: Zhang Xiao-lei, Dong Guowei, Feng Shi-jin, Li Jianping, and Li Fuhao
Subjects: business.industry, Mechanical Engineering, Vibration control, Structure (category theory), Building and Construction, Structural engineering, Masonry, Geotechnical Engineering and Engineering Geology, Strength of materials, Vibration, Building Location, Frequency domain, Environmental science, Time domain, business, Civil and Structural Engineering
Abstract: Many types of buildings have been widely constructed in the vicinity of subway lines in China. Normal life and business activities are hampered by excessive subway-induced vibrations. This study aims to determine the influence of structure characteristics on structure-borne vibrations, generally based on experimental results. Vibration measurements were performed in four typical sites in Wuxi, China, involving over-track buildings, along-track buildings, frame structure buildings and a masonry building. Special structure designs like structure transfer floor were also included. Then, the captured data was analyzed in the time domain and the frequency domain. Furthermore, the influence of building location, structure type and structure layout was investigated. Finally, vibrations were evaluated with ISO and Chinese criteria and structure optimization for vibration attenuation was proposed. It is found that over-track buildings are more severely affected than along-track buildings. Higher frequency contents (20–60 Hz) in over-track buildings and lower frequency contents (0–10 Hz) in along-track buildings should be seriously considered in vibration control. Weaker structure member joints and lower material strength would be beneficial to over-track buildings while the inverse situation would be beneficial to along-track buildings. The application of structure transfer floor — generally stiffer structure members and structure discontinuity-is also beneficial.
Published: 2021
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8. The Extended Bag of Words Model for Visual Recognition and Categorization

Author: Miaomiao Liu, Zhang Xiao, Li Xinde, and Jin Xiaobin
Subjects: Visual recognition, Categorization, Bag-of-words model in computer vision, Bag-of-words model, business.industry, Computer science, Artificial intelligence, business, computer.software_genre, computer, Natural language processing
Abstract: With the development of science and technology, more and more images need to be recognized and categorized. Although the classical Bag of Words (BoW) model has played a great role in the past, there are still many limitations about it, i.e. low precision and accuracy, high complexity of computation, etc. In this paper, it is improved and extended from four ways. Firstly, the features filtered from the background are sampled to reduce the influence of background noise. Secondly, the spatial relationship among all features is integrated with the classical BoW vector to improve the accuracy of recognition and categorization. Thirdly, vocabulary tree is constructed by applying hierarchical K mean value, in order to obtain more reasonable vocabulary list and greatly reduce the clustering time. Fourthly, a weighted visual word histogram is considered, in order to stand out the essential difference among images. At last, some experiments are conducted to show the advantage of the proposed method.
Published: 2021
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9. Multiple influences of internal curing and supplementary cementitious materials on the shrinkage and microstructure development of reefs aggregate concrete

Author: Chenga, Shukai, Shuia, Zhonghe, Yu, Rui, Sun, Tao, and Zhang, Xiao
Subjects: Concrete curing -- Analysis, Permeability -- Analysis, Compressive strength -- Analysis, Cements (Building materials) -- Mechanical properties -- Analysis, Business, Construction and materials industries
Abstract: ABSTRACT This paper presents the multiple influences of internal curing (IC) and supplementary cementitious materials (SCM) on the shrinkage and microstructure development of reefs aggregate concrete (RAC). Different RAC are [...]
Published: 2017
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10. Experimental study on use of lightweight foam concrete as subgrade bed filler of ballastless track

Author: Huang, Jun-jie, Su, Qian, Zhao, Wen-hui, Li, Ting, and Zhang, Xiao-xi
Subjects: Building materials industry -- Management -- Reports, Company business management, Business, Construction and materials industries
Abstract: ABSTRACT Controlling settlement of ballastless track subgrade in special soil areas is an ongoing scientific problem in the construction and operation of high-speed railways-primarily because of the consolidation settlement of [...]
Published: 2017
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11. Experimental observation of the self-healing microcapsules containing rejuvenator states in asphalt binder

Author: Su, Jun-Feng, Han, Shan, Wang, Ying-Yuan, Schlangen, Erik, Han, Ning-Xu, Liu, Bing, Zhang, Xiao-Long, Yang, Peng, and Li, Wei
Subjects: Asphalt -- Research -- Mechanical properties, Binders (Materials) -- Research, Business, Construction and materials industries
Abstract: ABSTRACT Microcapsules containing rejuvenator are particles used to increase the self-healing capability of asphalt. To date, no reports focus on studying their behaviors in asphalt binders between the aggregates. The [...]
Published: 2017
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12. Effect and Mechanism of TL1A Expression on Epithelial-Mesenchymal Transition during Chronic Colitis-Related Intestinal Fibrosis

Author: David Q. Shih, Stephan R. Targan, Yang Mingyue, Han Fei, Jia Wenxiu, Zhang Xiao-lan, Luo Yuxin, Li Chenyang, Song Jia, Zhang Hong, and Wu Mengyao
Subjects: Adult, Male, Tumor Necrosis Factor Ligand Superfamily Member 15, 0301 basic medicine, Epithelial-Mesenchymal Transition, Article Subject, Bone Morphogenetic Protein 7, Immunology, Mice, Transgenic, Inflammation, Inflammatory bowel disease, Pathogenesis, Mice, 03 medical and health sciences, 0302 clinical medicine, Immune system, Fibrosis, Pathology, Animals, Humans, RB1-214, Medicine, Epithelial–mesenchymal transition, business.industry, Reproducibility of Results, Cell Biology, Middle Aged, Cadherins, Colitis, medicine.disease, Ulcerative colitis, Intestines, Mice, Inbred C57BL, 030104 developmental biology, Immune System, Chronic Disease, Cancer research, Female, 030211 gastroenterology & hepatology, Tumor necrosis factor alpha, medicine.symptom, business, HT29 Cells, Research Article
Abstract: Background and Aims. Recent evidences reveal that epithelial to mesenchymal transition (EMT) exacerbates the process of intestinal fibrosis. Tumor necrosis factor-like ligand 1A (TL1A) is a member of the tumor necrosis family (TNF), which can take part in the development of colonic inflammation and fibrosis by regulating immune response or inflammatory factors. The purpose of this study was to elucidate the possible contribution of TL1A in onset and progression of intestinal inflammation and fibrosis through EMT. Methods. Colonic specimens were obtained from patients with inflammatory bowel disease (IBD) and control individuals. The expression levels of TL1A and EMT-related markers in intestinal tissues were evaluated. Furthermore, the human colorectal adenocarcinoma cell line, HT-29, was stimulated with TL1A, anti-TL1A antibody, or BMP-7 to assess EMT process. In addition, transgenic mice expressing high levels of TL1A in lymphoid cells were used to further investigate the mechanism of TL1A in intestinal fibrosis. Results. High levels of TL1A expression were detected in the intestinal specimens of patients with ulcerative colitis and Crohn’s disease and were negatively associated with the expression of an epithelial marker (E-cadherin), while it was positively associated with the expression of interstitial markers (FSP1 and α-SMA). Transgenic mice with high expression of TL1A were more sensitive to dextran sodium sulfate and exhibited severe intestinal inflammation and fibrosis. Additionally, the TGF-β1/Smad3 pathway may be involved in TL1A-induced EMT, and the expression of IL-13 and EMT-related transcriptional molecules (e.g., ZEB1 and Snail1) was increased in the intestinal specimens of the transgenic mice. Furthermore, TL1A-induced EMT can be influenced by anti-TL1A antibody or BMP-7 in vitro. Conclusions. TL1A participates in the formation and process of EMT in intestinal fibrosis. This new knowledge enables us to better understand the pathogenesis of intestinal fibrosis and identify new therapeutic targets for its treatment.
Published: 2021
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13. Accuracy Assessment of a Novel Radiographic Method to Evaluate Guided Bone Regeneration Outcomes Using a 3D-Printed Model

Author: Zhang Xiao (张枭), Shi Junyu (史俊宇), Lai Hongchang (赖红昌), Li Yuan (李元), and Zhang Xiaomeng (张晓梦)
Subjects: 3d printed, Reproducibility, Cone beam computed tomography, Multidisciplinary, business.industry, Radiography, Segmentation, business, Bone regeneration, Volumetric measurement, Mathematics, Biomedical engineering, Interpolation
Abstract: The aim of this study was to evaluate the accuracy and reproducibility of a morphological contour interpolation (MCI) based segmentation method for the volumetric measurement of bone grafts around implants. Three 3D-printed models (one with a cylinder and two with a geometrically-complex form) were fabricated to simulate implant placement with a simultaneous guided bone regeneration (GBR) procedure. All models were scanned using a cone beam computed tomography (CBCT) instrument with the same parameters. The true volumes of the bone grafts in the models were assessed using computer-aided calculation (controls). For the test measurements, both manual and MCI-based methods were used. A comparison between the measured and true volumes was performed to evaluate the accuracy. The coefficients of variation of repeated measurements were calculated to evaluate the reproducibility. In addition, the execution time was recorded and a comparison between the two methods was performed. The high accuracy of the MCI-based method was found with differences between the measured value and actual volume, which never exceeded 7.3%. Excellent reproducibility was shown, with coefficients of variation never exceeding 1.1%. A shorter execution time was observed for the MCI-based method than for the manual method. Within the confines of this study, the MCI-based method may be suitable for volumetric measurements of grafted bone around implants.
Published: 2021
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14. HRCT imaging features of systemic sclerosis-associated interstitial lung disease

Author: Zhang Guangfeng, Lin Haobo, Zhou Zexuan, Xu Ting, and Zhang Xiao
Subjects: Pathology, medicine.medical_specialty, business.industry, Interstitial lung disease, Medicine, respiratory system, business, medicine.disease, respiratory tract diseases
Abstract: Background: The aim of the study was to evaluate radiographic features of systemic sclerosis-associated interstitial lung disease. Patients and methods: 116 patients with systemic sclerosis-associated interstitial lung disease (SSc-ILD) from 2010 to 2019 comprised our retrospective study. All patients were subject to high resolution computed tomography (HRCT). ILD patterns were classified into 7 patterns as IIPs and analyzed with pathology. We chose two staging method and two semi-quantitative score methods to evaluate the HRCT performance and analyzed with pulmonary function tests. Results: Ground-glass opacities were the most common presentation on HRCT, followed by interlobular septal thickening, reticular opacities, intralobular interstitial thickening; honeycombing, traction bronchiectasis and nodules can also be observed. The most common pattern of SSc-ILD was nonspecific interstitial pneumonia (NSIP), secondly was UIP. There was no difference in ILD pattern between HRCT and pathology, and revealed a high congruence. The four HRCT evaluating methods presented in this study all had significant relationships with PETs. Conclusion: The most common pattern of SSc-ILD was nonspecific interstitial pneumonia (NSIP). The ILD patterns of HRCT coincide very well with histology, and will replace pathology as the gold standard for diagnosis and evaluation of SSc-ILD.
Published: 2021
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15. Observation on therapeutic efficacy of thunder-fire moxibustion for hypomenorrhea after induced abortion

Author: Gu Hai-yan, Lu Ying, and Zhang Xiao-lei
Subjects: medicine.medical_specialty, biology, business.industry, medicine.medical_treatment, Traditional Chinese medicine, Moxibustion, Abortion, Gastroenterology, Sex hormone-binding globulin, Complementary and alternative medicine, Internal medicine, Hypomenorrhea, medicine, Acupuncture, biology.protein, Clinical efficacy, medicine.symptom, business, Hormone
Abstract: To observe the clinical efficacy of thunder-fire moxibustion for hypomenorrhea after induced abortion. A total of 74 patients with hypomenorrhea after induced abortion were randomized into two groups, with 37 cases in each group. The control group was treated with conventional hormone sequential therapy, and the observation group was treated with thunder-fire moxibustion. The course of treatment was 3 menstrual cycles. The traditional Chinese medicine (TCM) symptom scores, menstrual volume, endometrial thickness and the sex hormone levels were observed before and after treatment. The clinical efficacy was compared after treatment. The total effective rate in the observation group and the control group was 91.4% and 73.5%, respectively, and the difference between the two groups was statistically significant (P
Published: 2021
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16. High Performance, Eco-Friendly SPM Cleaning Technology Using Integrated Bench-Single Wafer Cleaning System

Author: Bruce W. Lee, Fang Li, Sally Ann Henry, She Na Jia, Fu Ping Chen, Tao Zhang, Hong Li, Chung Wei Wang, David H. Wang, Yi Yang, Wen Jun Wang, Jun Huang, Hai Bo Lei, Zhang Xiao-Yan, Jane Wang, Yunho Kim, Jason Lee, and Zhang Yu Yu
Subjects: Hardware_MEMORYSTRUCTURES, Materials science, business.industry, General Materials Science, Wafer, Condensed Matter Physics, Process engineering, business, Environmentally friendly, Atomic and Molecular Physics, and Optics
Abstract: Batch SPM systems do not meet the current clean specification/requirements below 28nm. Single wafer SPM systems use a high volume of chemistry which runs to drain, while meeting the cleaning specifications below 28nm. The work in this paper describe the use of a batch SPM system and a single wafer clean in an integrated system, Ultra-C Tahoe which results in meeting the technical specification and using less that 80% of the SPM chemistry used in single wafer systems. The data collected shows this new system meet the specifications, whilst saving more than 80%of SPM chemistry.
Published: 2021
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17. Gauss Projection Band Changing Complex Transformation App in Android System

Author: Li Chunyun, Chen Yonghong, Zeng Echun, Liu Dahai, Zeng Qinggui, and Zhang Xiao
Subjects: Computer science, business.industry, Applied Mathematics, Gauss, Computer vision, Artificial intelligence, Android (operating system), Projection (set theory), business
Published: 2021
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18. Decentralized Economic Dispatching of Multi-Micro Grid Considering Wind Power and Photovoltaic Output Uncertainty

Author: Zhang Xiao-hui, Zhong Jiaqing, and Gao Wenbo
Subjects: Mathematical optimization, Wind power, General Computer Science, business.industry, Computer science, decentralized economic scheduling, Photovoltaic system, General Engineering, Scheduling (production processes), Robust optimization, Decoupling (cosmology), Grid, Partition (database), TK1-9971, Alternating direction method of multipliers (ADMM), multi-micro grid, Measurement uncertainty, General Materials Science, wind power generation, Electrical engineering. Electronics. Nuclear engineering, business
Abstract: In this paper, the decentralized economic scheduling problem of multi-micro grid is studied on the basis of considering the uncertainty of wind power and photovoltaic output. Firstly, in order to meet the independent and autonomous requirements of decentralized scheduling, the decoupling method of public connection points, which is more suitable for the multi-micro grid structure, is adopted to partition the multi-micro grid regions. Then, considering the uncertainty of wind-wind output, a decentralized economic dispatching model of multi-micro grid with robust optimization participation is proposed to minimize the economic cost. Finally, the improved Alternating direction method of multipliers is used to solve the decentralized economic scheduling problem of multi-micro grid. The feasibility and superiority of the improved algorithm are verified by simulation test and comparative analysis. The decentralized autonomy of multi-micro grid scheduling can be realized, and the random uncertainty of landscape can be effectively dealt with.
Published: 2021

19. Stray light noise removal method of star maps based on intensity prior

Author: Yang Xia, Lin Bin, Zhang Xiao-hu, Zhang Xin, and Wang Kunpeng
Subjects: Physics, Optics, business.industry, Stray light, Star (graph theory), business, Noise removal, Atomic and Molecular Physics, and Optics, Intensity (heat transfer)
Published: 2021
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20. Do temporary increases in information asymmetry affect the cost of equity?

Author: Levi, Shai and Zhang, Xiao-Jun
Subjects: Liquidity (Finance) -- Economic aspects, Business, general, Business
Abstract: Prior literature finds that long-lasting changes in firms' disclosure policies and information environment affect the cost of equity. Information asymmetry, however, also changes during the fiscal quarter. Firms disclose information periodically, and in between disclosure dates, traders can obtain private information, and adverse-selection risk increases. Such temporary increases in information asymmetry are usually considered to be diversifiable or too small to impact expected stock returns. In addition, investors may postpone trades or sell other assets in their portfolio on high information asymmetry days. We, however, find that returns increase significantly on days during the fiscal quarter when adverse-selection risk is high and liquidity low. Consistent with theory, we show that temporary asymmetry affects returns when investors demand liquidity and market makers bear risk for carrying capacity and providing it. Keywords: information asymmetry; liquidity; earnings announcements; cost of equity History: Received April 6, 2012; accepted November 12, 2013, by Mary Barth, accounting. Published online in Articles in Advance June 4, 2014., 1. Introduction Some theories suggest that information asymmetry can affect expected stock returns. (1) Information asymmetry is often considered a long-term firm characteristic, and prior literature tests the effect of [...]
Published: 2015
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21. Microeconomic reform and income distribution: the case of Australian ports and rail freight

Author: Verikios, George and Zhang, Xiao-Guang
Subjects: Economic reform -- Evaluation, Income distribution -- Laws, regulations and rules -- Forecasts and trends, Coastal shipping -- Laws, regulations and rules -- Economic aspects, Rail freight -- Laws, regulations and rules, Microeconomics -- Laws, regulations and rules -- Analysis, Government regulation, Market trend/market analysis, Business, Economics
Abstract: I. INTRODUCTION Ports and railways in Australia have a history that dates from the 19th century when intra-colonial railway lines were first established: from this time till the development of [...]
Published: 2015
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22. ADRB3 expression in tumor cells is a poor prognostic factor and promotes proliferation in non-small cell lung carcinoma

Author: Xiangting Tian, Meng Zheng, Ding-Zhang Xiao, Zhi Xie, Shu-Guang Lin, Xinghua Hou, Haidan Liang, and Zhiling Zhou
Subjects: Male, Monoclonal antibody, Cancer Research, Lung Neoplasms, Macrophage, Immunology, Cell, Inflammation, Mice, 03 medical and health sciences, Antineoplastic Agents, Immunological, 0302 clinical medicine, Carcinoma, Non-Small-Cell Lung, Macrophages, Alveolar, Carcinoma, Animals, Humans, Immunology and Allergy, Medicine, Lung cancer, PI3K/AKT/mTOR pathway, Cell Proliferation, 030304 developmental biology, 0303 health sciences, business.industry, Antibodies, Monoclonal, Prognosis, medicine.disease, respiratory tract diseases, medicine.anatomical_structure, Oncology, Tumor progression, Receptors, Adrenergic, beta-3, ADRB3, 030220 oncology & carcinogenesis, Cancer cell, mTOR, Cancer research, Female, Original Article, medicine.symptom, business
Abstract: The cross-talk between cancer cells and monocyte-derived alveolar macrophages (Mo-AMs) promotes non-small cell lung carcinoma (NSCLC) progression. In this study, we report that both cancer cells and Mo-AMs robustly express beta 3-adrenergic receptor (ADRB3) in NSCLC. ADRB3 supports lung cancer cells proliferation and promotes chronic inflammation. Genetic and pharmacologic inhibition of ADRB3 reverses tumor growth and inflammation in mouse. Furthermore, we demonstrate that M5D1, a novel anti-ADRB3 monoclonal antibody, inhibits human lung cancer cells proliferation and inflammation via affecting the intracellular mTOR pathway and activating p53. In NSCLC patients, we confirmed that upregulation of ADRB3 expression correlates with tumor progression and poor prognosis. Altogether, these results shed light on the role of ADRB3 in NSCLC and suggest that M5D1 could become powerful antitumor weapons. Electronic supplementary material The online version of this article (10.1007/s00262-020-02627-3) contains supplementary material, which is available to authorized users.
Published: 2020
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23. Production of inter-connective porous dental implants by computer-aided design and metal three-dimensional printing

Author: Zhang Zhiguang, Sun Yangpeng, Zhang Xiao, Jianyu Chen, and Feilong Deng
Subjects: Male, Computer science, Finite Element Analysis, 0206 medical engineering, Biomedical Engineering, Dentistry, 02 engineering and technology, Porous implant, Bone and Bones, Biomaterials, Dental Prosthesis, stomatognathic system, Osseointegration, Animals, Computer Simulation, Dental alveolus, Dental Implants, Custom made implant, business.industry, Lasers, X-Ray Microtomography, 021001 nanoscience & nanotechnology, 020601 biomedical engineering, stomatognathic diseases, Dental Prosthesis Design, Metals, Three dimensional printing, Printing, Three-Dimensional, Computer-Aided Design, Rabbits, 0210 nano-technology, business, Porosity
Abstract: Even though dental implants are considered reliable for replacing missing teeth, their use in medically compromised alveolar bone or under excessive occlusal force remains problematic. Here, we dev...
Published: 2020
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24. Flat-field calibration method for large diameter survey mirror aperture splicing

Author: Zhang Tian-yi, Zhang Xiao-hui, and LU Shi-tong
Subjects: Physics, Optics, Aperture, business.industry, RNA splicing, Field calibration, Large diameter, business, Atomic and Molecular Physics, and Optics
Published: 2020
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25. Three-dimensional deformation measurement based on digital speckle pattern interferometry

Author: Zhao Qihan, Zhang Xiao, Yan Peizheng, Chen Weijie, Bao Fengqing, and Wang Yong-hong
Subjects: Interferometry, Speckle pattern, Three dimensional deformation, business.industry, Computer science, System of measurement, Acoustics, Measure (physics), Deformation (meteorology), Aerospace, business, Atomic and Molecular Physics, and Optics, Reliability (statistics)
Abstract: Three-dimensional deformation can be converted into stress-strain distribution, which is the key parameter in material performance test and structure reliability analysis. Among many three-dimensional deformation measurement techniques, digital speckle pattern interferometry can measure the three-dimensional deformation information with high precision. And it plays a very important role in the industries of aerospace, automotive, advanced equipment manufacturing, civil engineering, biomedicine and so on. Based on the basic principle of speckle pattern interferometry, several kinds of three-dimensional deformation speckle pattern interferometry were introduced in detail and their advantages as well as disadvantages were analyzed and compared; at the same time, the research progress and latest application of three-dimensional deformation speckle pattern interferometry at home and abroad were introduced; at last, the development trend of three-dimensional deformation speckle pattern interferometry in dynamic synchronous measurement, measurement system simplification and application range broadening was prospected.
Published: 2020
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26. Characteristics of concrete cracks and their influence on chloride penetration

Author: Wang, Hai-Long, Dai, Jian-Guo, Sun, Xiao-Yan, and Zhang, Xiao-Long
Subjects: Reinforced concrete -- Analysis -- Mechanical properties, Business, Construction and materials industries
Abstract: ABSTRACT Concrete cracking usually is an unavoidable phenomenon in reinforced concrete (RC) structures and has a significant effect on chloride diffusion and thus the deterioration of the structures. However, actual [...]
Published: 2016
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27. Multilayer Domain Adaptation-Based Convolutional Auto Encoder for Fault Diagnosis under Different Speeds

Author: Han Baokun, Zhang Xiao, Wang Jinrui, Zhang Zongzhen, Ji Shanshan, and Jia Meixia
Subjects: Domain adaptation, business.industry, Computer science, business, Fault (power engineering), Autoencoder, Computer hardware
Published: 2021
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28. The efficacy and safety of small incision open reduction and intramedullary nail fixation surgery in the treatment of simple tibial shaft fracture

Author: chen shi, xu chun cheng, yang jian cheng, yu jia nan, hong chuan, he shan hai, and zhang xiao lei
Subjects: Intramedullary rod, Fixation (surgical), medicine.medical_specialty, Small incision, law, business.industry, medicine.medical_treatment, medicine, Fracture (geology), business, Reduction (orthopedic surgery), law.invention, Surgery
Abstract: Objective: To explore the clinical efficacy and safety of small incision open reduction and intramedullary nail internal fixation surgery in the treatment of simple tibial shaft fracture compared to the closed reduction surgery. Methods: A total of fifty patients with simple tibial shaft fractures admitted to our hospital were randomly and equally assigned into the observation group and the control group. Patients in the observation group received small incision open reduction surgery with intramedullary nail while patients in the control group received the closed reduction surgery. The clinical efficacy, prognosis as well as safety profile were compared between the two groups. Results: Our data indicated that the average bleeding volume of patients in the observation group was increased while the operation time was decreased compared to the control group. No significant difference of postoperative complications, fracture healing time, and Johner-Wruhs scores was identified between the two groups. Conclusion: The small incision open reduction surgery can significantly shorten the operation time while achieved a similar clinical efficacy compared to the closed reduction surgery in simple tibial shaft fracture.
Published: 2021
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29. Preparation of carbon fiber reinforced cement-based composites using self-made carbon fiber mat

Author: Sun, Ming-qing, Li, Jun, Wang, Ying-jun, and Zhang, Xiao-yu
Subjects: Composite construction -- Analysis -- Properties, Cement -- Analysis -- Properties, Business, Construction and materials industries
Abstract: ABSTRACT The carbon fiber mat was first manufactured in the laboratory by means of the following procedure: dispersing chopped carbon fibers in the dispersant solution with the concentration of 0.4%, [...]
Published: 2015
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30. Electricity–gas‐integrated energy planning based on reward and penalty ladder‐type carbon trading cost

Author: Zhong Jiaqing, Zhang Xiao-hui, Gao Wenbo, and Liu Xiaoyan
Subjects: Economic efficiency, Mathematical optimization, Total cost, business.industry, Computer science, 020209 energy, Business system planning, Energy Engineering and Power Technology, 02 engineering and technology, Energy planning, Investment (macroeconomics), Energy conservation, 020401 chemical engineering, Control and Systems Engineering, 0202 electrical engineering, electronic engineering, information engineering, Electricity, 0204 chemical engineering, Electrical and Electronic Engineering, Activity-based costing, business
Abstract: Given the background of energy Internet and low-carbon electricity, the integrated energy system has become an important carrier of energy conservation and emission reduction. This study establishes an electric–gas-integrated energy system planning model that considers carbon trading. First, carbon trading is introduced into the planning model. A reward and punishment ladder-type carbon trading cost model is proposed, and its restriction on carbon emission is analysed. On this basis, a planning model is established, to minimise the total costs including the investment cost, operation cost, and carbon trading cost. Finally, the discrete bacterial colony chemotaxis algorithm is applied to solve this model. The simulation results of the three planning models are compared and analysed by simulation examples, which verify the effectiveness of the proposed model in balancing the low carbon and economic efficiency of the system. The impact of carbon trading price on system planning and operation is analysed.
Published: 2019
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31. Double-image encryption based on interference and logistic map under the framework of double random phase encoding

Author: Tian Ailing, Sui Liansheng, Du Cong, Zhang Xiao, and Asundi Anand
Subjects: Computer science, business.industry, Mechanical Engineering, 02 engineering and technology, 021001 nanoscience & nanotechnology, Interference (wave propagation), Encryption, 01 natural sciences, Random sequence, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials, 010309 optics, Encoding (memory), Computer Science::Multimedia, 0103 physical sciences, Ciphertext, Cryptosystem, Chosen-plaintext attack, Electrical and Electronic Engineering, Logistic map, 0210 nano-technology, business, Algorithm, Computer Science::Cryptography and Security
Abstract: A novel double-image encryption approach has been proposed based on optical interference and logistic map. Initially, original images are rearranged into two scrambled components with the use of the random sequence engendered based on the logistic map with the given conditions such as initial value and bifurcate parameter. One component is used as the input image of the framework of double random phase encoding and encrypted into the ciphertext. Another is decomposed into two phase masks, which are placed into the input plane and transform plane of double random phase encoding, respectively. To strength the nonlinearity of the cryptosystem, these phase masks considered as the main secret keys are further encoded by the aid of two random sequences. Because these keys are produced in the encryption process and directly related to original images, the proposed scheme has high resistance against the potential attacks such as chosen plaintext attack. Meanwhile, the parameters such as wavelength, axial distance, and conditions of the logistic map are considered as additional keys, which can enhance the security level further. Most importantly, the annoying silhouette problem existed in the interference-based encryption methods can be avoided effectively. A set of numerical simulations are presented to demonstrate the validity and feasibility of the proposed technique.
Published: 2019
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32. Imaging Features of the Whole Uterus Volume CT Perfusion and Influence Factors of Blood Supply: A Primary Study in Patients with Cervical Squamous Carcinoma

Author: Wang Fei Fei, Zhang Xiao Miao, Dong Yue, Pang Hui Ting, Yu Tao, Dong Rui Tong, and Luo Ya Hong
Subjects: Adult, Male, Intraclass correlation, Perfusion Imaging, Uterine Cervical Neoplasms, Perfusion scanning, Blood volume, Spearman's rank correlation coefficient, 030218 nuclear medicine & medical imaging, 03 medical and health sciences, 0302 clinical medicine, Multidetector Computed Tomography, Biopsy, medicine, Humans, Radiology, Nuclear Medicine and imaging, Aged, medicine.diagnostic_test, business.industry, Reproducibility of Results, Magnetic resonance imaging, Cone-Beam Computed Tomography, Middle Aged, Magnetic Resonance Imaging, Squamous carcinoma, 030220 oncology & carcinogenesis, Carcinoma, Squamous Cell, Female, business, Nuclear medicine, Perfusion
Abstract: Rationale and Objectives To explore the imaging features of whole uterus volume CT perfusion (vCTP) and the influence factors of blood supply in cervical squamous carcinoma (CSC). Materials and Methods vCTP was performed on a 640-slice computed tomography system in 43 patients with CSC diagnosed by biopsy, and 24 cases of them underwent magnetic resonance imaging. The size of the tumor was measured on vCTP and magnetic resonance (MR) images. Perfusion parameters, including arterial blood flow (AF), blood volume, and permeability surface (PS), were measured by two radiologists, using interclass correlation coefficient to evaluate the interobserver reliability. The difference of tumor size and perfusion data was analyzed by paired t test and rank sum test. The correlation of perfusion parameters with some factors was analyzed by Pearson or Spearman correlation analysis. Results Tumor sizes were not significantly different between vCTP and MR images. The interclass correlation coefficient of each parameter was 0.818–0.945. The AF value of CSC was significantly higher than normal uterine body, and the blood volume and PS values of CSC were not statistically different compared with those of normal uterine body. There was no significant difference in AF value of CSC among different FIGO stages and pathological grades. The AF and PS values of CSC were negatively correlated with the age of the patients. Conclusion The vCTP could accurately shows the size of the CSC with use of MR as the reference standard, and its perfusion parameters have good measurement stability; the CSC was hypervascular, but this trend was less pronounced in older women.
Published: 2019
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33. Silhouette-free interference-based multiple-image encryption using cascaded fractional Fourier transforms

Author: Anand Asundi, Huang Chongtian, Sui Liansheng, Tian Ailing, and Zhang Xiao
Subjects: Computer science, business.industry, Mechanical Engineering, 02 engineering and technology, Function (mathematics), 021001 nanoscience & nanotechnology, Interference (wave propagation), Encryption, 01 natural sciences, Atomic and Molecular Physics, and Optics, Fractional Fourier transform, Electronic, Optical and Magnetic Materials, Silhouette, 010309 optics, symbols.namesake, Fourier transform, 0103 physical sciences, Ciphertext, symbols, Cryptosystem, Electrical and Electronic Engineering, 0210 nano-technology, business, Algorithm, Computer Science::Cryptography and Security
Abstract: An optical approach of silhouette-free multiple-image encryption based on interference is proposed, with two layers to enhance the level of security. In the first layer, a group of plain images are encoded into an amplitude distribution, called interim, using the cascaded fractional Fourier transforms. In the second layer, the interim is encrypted into two noisy ciphertext images. The two layers are compactly combined into a single whole to assure that the inherent silhouette problem is removed through the involvement of a random phase-only mask as the built-in function of cryptosystem. In addition to the phase mask keys generated in the process of encryption, the security is enhanced further by considering the fractional order as an additional key. Numerical simulations are given to demonstrate the feasibility and validity of this approach.
Published: 2019
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34. Effect of the Spool Cone Angle on the Erosion of a Novel Inner Blowout Preventer

Author: Chen Long and Zhang Xiao-dong
Subjects: Finite volume method, Computer simulation, business.industry, Mechanical Engineering, Mechanics, Computational fluid dynamics, Core (optical fiber), Mechanics of Materials, Turbulence kinetic energy, General Materials Science, Ligand cone angle, Safety, Risk, Reliability and Quality, business, Blowout preventer, SIMPLE algorithm, Geology
Abstract: This paper presents a novel structure with reliable sealing property for the inner blowout preventer (BOP) device aiming at improving its safety and reliability during drilling process. Namely, the study of effects of flow rate and seat cone angle on the erosion wear rate of inner BOP is performed based on the numerical simulation analyses of inner flow field of inner BOP by means of computational fluid dynamics method with various models including RNG k–e model, discrete phase model and Tabakoff–Grant erosion model. The finite volume method is used for the discrete calculation, and the SIMPLE algorithm is applied for solving the continuity, momentum, energy and turbulent kinetic energy equations. The results reveal that some positions of the valve core are prone to erosion wear, and the optimal angle of the taper angle of the upper and lower valve seats for the inner BOP is 25°. Finally, the static stress analyses and leak tests validate the reliability of the inner BOP. These analyses provide the basis for structural design of the inner BOP.
Published: 2019
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35. Clinical analysis of high-intensity focussed ultrasound ablation for abdominal wall endometriosis: a 4-year experience at a specialty gynecological institution

Author: Wang Jin-Juan, Cheng Jiu-mei, Ye Hong, Duan Hua, Guo Ying-Shu, Zhang Xiao-Ying, and Zang Chun-Yi
Subjects: Adult, Cancer Research, medicine.medical_specialty, Time Factors, lcsh:Medical technology, genetic structures, Physiology, medicine.medical_treatment, Specialty, Endometriosis, high-intensity focussed ultrasound, abdominal wall endometriosis, ablation, 030218 nuclear medicine & medical imaging, Abdominal wall, 03 medical and health sciences, Young Adult, 0302 clinical medicine, Physiology (medical), Medicine, Humans, mri, Clinical pathology, business.industry, ultrasound, High intensity, Ultrasound, medicine.disease, Ablation, medicine.anatomical_structure, lcsh:R855-855.5, 030220 oncology & carcinogenesis, High-Intensity Focused Ultrasound Ablation, Female, Radiology, business
Abstract: Objective: To evaluate the long-term clinical effect of high-intensity focussed ultrasound (HIFU) as a non-invasive modality for ablation of abdominal wall endometriosis (AWE) foci. Methods: All women who were diagnosed with cutaneous endometriosis and underwent HIFU ablation and 4-year follow-up were included. Patient symptoms, imaging performed, HIFU ablation, recurrence, lesion location, size and number were collected and analyzed. Results: A total of 51 women with 57 painful abdominal wall masses with a median volume of 4.00 cm3 and a mean age of 30.5±2.12 years were treated with HIFU. The main symptoms were a palpable painful abdominal mass (93%), protrusion of the skin (28.1%, 16) or lack of protrusion of the skin (71.9%, 41). Ultrasound was initially performed in 100% (51) of women, whereas 6% (3) required MRI examinations to distinguish the features and range of the masses. Ablation was performed with a median 300 s of sonication time, 40 min treatment time, 150 W of power and 41800 J of total energy to treat lesions that were a median volume of 3.83 cm3. No severe complications occurred, except in one patient with a first-degree skin burn, during the 48-month follow-up period. The pooled recurrence of cutaneous endometriosis occurred in 3.9% (2) of women. Conclusion: The diagnosis of AWE should be confirmed with imaging of the lesion number, location, size and features before HIFU ablation. HIFU should be the first choice for the treatment of AWE as it is a non-invasive method, with high efficiency and safety and rapid postoperative recovery.
Published: 2019

36. Formation of interface defects of ZnO/ZnS core-shell nanowires and its optical properties investigations

Author: 赵海霞 Zhao Hai-xia, 王登魁 Wang Dengkui, 方铉 Fang Xuan, 王颜彬 Wang Yan-bin, 李永峰 Li Yong-feng, 王晓华 Wang Xiaohua, 楚学影 Chu Xue-ying, 魏志鹏 Wei Zhi-peng, 房丹 Fang Dan, and 张晓东 Zhang Xiao-dong
Subjects: Core shell, Materials science, Interface (Java), business.industry, Nanowire, Optoelectronics, business, Atomic and Molecular Physics, and Optics
Published: 2019
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37. Fabrication and Near-infrared Spectral Modulation of Au/Bi Ions Co-doped Silica Thin Films

Author: 张会红 Zhang Hui-hong, 汪鹏君 Wang Peng-jun, 陈若望 Chen Ruo-wang, 张晓伟 Zhang Xiao-wei, 张跃军 Zhang Yue-jun, and 束俊鹏 Shu Jun-peng
Subjects: Radiation, Fabrication, Materials science, business.industry, Modulation, Near-infrared spectroscopy, Optoelectronics, Thin film, Condensed Matter Physics, business, Co doped, Electronic, Optical and Magnetic Materials, Ion
Published: 2019
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38. Tensor representation based target detection for hyperspectral imagery

Author: 郑茜 Zheng Xi, 潘志斌 Pan Zhi-bin, 张小荣 Zhang Xiao-rong, and 胡炳樑 Hu Bing-liang
Subjects: Computer science, business.industry, Tensor representation, Hyperspectral imaging, Pattern recognition, Artificial intelligence, business, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published: 2019
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39. Aspheric optimization design of fisheye lens optical system

Author: Lyu Lijun and Zhang Xiao
Subjects: Fisheye lens, Optics, Computer science, business.industry, business, Atomic and Molecular Physics, and Optics
Published: 2019
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40. Optically tunable random lasing from azo-dye-doped polymer dispersed liquid crystal in capillary tubes

Author: 王东硕 Wang Dong-shuo, 张晓东 Zhang Xiao-dong, 戴海涛 Dai Hai-tao, 罗丹 Luo Dan, 陈茂洲 Chen Mao-zhou, and 刘昌龙 Liu Chang-long
Subjects: Materials science, Random laser, Dye laser, business.industry, Capillary action, Physics::Optics, Laser, Electronic, Optical and Magnetic Materials, law.invention, Core (optical fiber), Full width at half maximum, law, Liquid crystal, Signal Processing, Optoelectronics, business, Instrumentation, Lasing threshold
Abstract: This study demonstrated the optically tunable random lasing from azo-dye-doped polymer dispersed liquid crystal (PDLC) in capillary tubes, in order to expand new applications for this device. The azo-dye-doped PDLC was prepared in glass capillaries with different core diameters, and the random lasing thresholds of these samples were measured respectively. The spectra of random lasers were measured with increasing the intensity of ultraviolet radiation. The experimental results show that the random laser threshold measurements of different core diameter capillary samples (100 μm, 300 μm, 500 μm) are 11.8 μJ/pulse, 8.6 μJ/pulse and 13.2 μJ/pulse. The experimental results also show that as the intensity of ultraviolet radiation increases (from 0 mW/cm2 to 150 mW/cm2), the random laser intensity decreases gradually, and the FWHM of the spectrum becomes wider. And the random lasing showed similar properties under the UV beam with different polarized directions during the optical tuning process. Our work verifies the possibility to fabricate miniature laser devices in cylindrical confinement structures, and extends the application scope of PDLC.
Published: 2019
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41. Optimized design of high-mode main support structure for airborne spectrometer

Author: 刘伟 Liu Wei, 颜昌翔 Yan Chang-xiang, 李颐 Li Yi, 张晓辉 Zhang Xiao-hui, and 顾志远 Gu Zhi-yuan
Subjects: Optics, Materials science, Spectrometer, business.industry, High mode, business, Atomic and Molecular Physics, and Optics, Electronic, Optical and Magnetic Materials
Published: 2019
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42. Monte-Carlo Ray-tracing Simulations of Perovskite Quantum Dots-based Luminescent Solar Concentrators

Author: 解凯贺 Xie Kai-he, 张晓伟 Zhang Xiao-wei, 汪鹏君 Wang Peng-jun, 张会红 Zhang Hui-hong, 束俊鹏 Shu Jun-peng, and 陈若望 Chen Ruo-wang
Subjects: Radiation, Materials science, business.industry, Quantum dot, Optoelectronics, Condensed Matter Physics, Luminescence, business, Distributed ray tracing, Electronic, Optical and Magnetic Materials, Perovskite (structure)
Published: 2019
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43. A Vision-based Pedestrian Comity Pre-Warning System

Author: Ming Yang, Yeqiang Qian, Junyao Lin, Quan Luo, Zhang Xiao, and Chunxiang Wang
Subjects: Comity, Focus (computing), Warning system, business.industry, Computer science, Deep learning, Pedestrian detection, ComputerApplications_COMPUTERSINOTHERSYSTEMS, Pedestrian, Collision, Computer security, computer.software_genre, Pruning (decision trees), Artificial intelligence, business, computer
Abstract: Despite the rapid development of assisted driving systems in recent years, vehicle-pedestrian accidents still account for a large proportion of serious traffic accidents. And most existing pedestrian protection methods in the ADAS system only focus on pedestrian detection and immediate collision warning, they fail to fully combine the lane detection to pedestrians for early warning. So the most existing pedestrian protection methods do not know when the warning should be produced, even maybe produce an unnecessary warning to distract the driver's attention. So we combine traditional detection algorithm with deep learning to develop a pedestrian comity pre-warning system based on vision algorithm and embedded system. The system includes a series of innovations such as dynamic ROI and similarity-based pruning. Finally, the experiment shows that the system has good performance and low consumption of computing resources.
Published: 2021
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44. Dynamic Influence Analysis of Virtual Inertia on Reconnection of Microgrid

Author: Zhang Xiao, Hao Yi, Fang Zhuo, Xiayu Liu, Zhenxiong Wang, and Haocheng Wang
Subjects: business.industry, Computer science, Mode (statistics), Process (computing), Inrush current, Computer Science::Hardware Architecture, Computer Science::Systems and Control, Control theory, Distributed generation, Harmonics, Physics::Space Physics, Transient (oscillation), Microgrid, business, Voltage
Abstract: The microgrid is useful in integrating renewable energy sources and distributed generation. Due to the inrush current, voltage harmonics and stability issue, microgrid cannot directly switch from the islanded mode to the grid-connected mode. Moreover, virtual inertia has proven to effectively improve the dynamic performance of the microgrid, which also influence the characteristics of mode switch. However, the influence of virtual inertia on microgrid reconnection has not been sufficiently studied. In this paper, the transient process in microgrid reconnection is modeled to analyze the inrush current. Based on the model, the influence of the virtual inertia on reconnection is analyzed, including the magnitude and response speed of the inrush current, and the stability of the reconnection of microgrid. Therefore, the proposed method for optimization of virtual inertia can improve the reconnection performance of microgrid, which eliminates the inrush current, and hence smooth the reconnection process. Finally, the simulation result verifies the effectiveness of the proposed method.
Published: 2021
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45. Rresearch on Operating mechanism and business mode for virtual power plant considering demand response

Author: Hu Dian-Gang, Zhang Xiao-Bin, Liang Tian, and Shen Weicheng
Subjects: Demand response, Virtual power plant, Market mechanism, Scheduling (production processes), Profitability index, Profit model, Business, Bidding, Business model, Industrial organization
Abstract: Constructing a virtual power plant plays an important role in improving the efficiency of new energy and the safety and stability of power grid.With the advancement of my country's power market construction, the commercial development of virtual power plants has ushered in greater opportunities.VPP is essentially an innovative business model generated by the aggregation of demand-side resources.The core significance of VPP is more reflected in the bidding of the power market, the expansion of the market operation scope and the business model.By centering on the business mechanism and market operation model of interaction between VPP and demand response,This paper introduces the participation mode and organizational framework for demand response participation in VPP operation.Researching VPP participates in the auxiliary service mode by scheduling flexible resources, and analyzed the operation and management model of virtual power plant and the profit model of VPP participation in demand response,exploring the promotion of clean energy consumption through VPP, finding out the market profit model that improves the demand-side response, and put forward policy support suggestions and market mechanism suggestions to promote VPP application and enhance its profitability.
Published: 2021
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46. Research on the Prediction of Green Plum Acidity Based on Improved XGBoost

Author: Wang Honghong, Yang Liu, Shen Luxiang, Fei Yeqi, Zilong Zhuang, Ying Liu, and Zhang Xiao
Subjects: green plum, Mean squared error, lcsh:Chemical technology, 01 natural sciences, Biochemistry, supervised learning, Article, Kernel principal component analysis, Analytical Chemistry, 0404 agricultural biotechnology, lcsh:TP1-1185, Electrical and Electronic Engineering, Instrumentation, Mathematics, Principal Component Analysis, business.industry, pH, 010401 analytical chemistry, Supervised learning, Discriminant Analysis, Pattern recognition, Prunus domestica, 04 agricultural and veterinary sciences, prediction, Linear discriminant analysis, 040401 food science, Atomic and Molecular Physics, and Optics, 0104 chemical sciences, hyperspectral, Kernel (statistics), Principal component analysis, Unsupervised learning, Gradient boosting, Artificial intelligence, business, Algorithms
Abstract: The acidity of green plum has an important influence on the fruit’s deep processing. Traditional physical and chemical analysis methods for green plum acidity detection are destructive, time-consuming, and unable to achieve online detection. In response, a rapid and non-destructive detection method based on hyperspectral imaging technology was studied in this paper. Research on prediction performance comparisons between supervised learning methods and unsupervised learning methods is currently popular. To further improve the accuracy of component prediction, a new hyperspectral imaging system was developed, and the kernel principle component analysis—linear discriminant analysis—extreme gradient boosting algorithm (KPCA-LDA-XGB) model was proposed to predict the acidity of green plum. The KPCA-LDA-XGB model is a supervised learning model combined with the extreme gradient boosting algorithm (XGBoost), kernel principal component analysis (KPCA), and linear discriminant analysis (LDA). The experimental results proved that the KPCA-LDA-XGB model offers good acidity predictions for green plum, with a correlation coefficient (R) of 0.829 and a root mean squared error (RMSE) of 0.107 for the prediction set. Compared with the basic XGBoost model, the KPCA-LDA-XGB model showed a 79.4% increase in R and a 31.2% decrease in RMSE. The use of linear, radial basis function (RBF), and polynomial (Poly) kernel functions were also compared and analyzed in this paper to further optimize the KPCA-LDA-XGB model.
Published: 2021
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47. Design of PBL Teaching Method Based on OBE Mode

Author: Zhang Xiao, Ji Ce, Cao Chunhong, and Geng Rong
Subjects: Enthusiasm, 020205 medical informatics, business.industry, Teaching method, media_common.quotation_subject, 05 social sciences, Professional development, 050301 education, Information technology, 02 engineering and technology, Creativity, Traditional education, ComputingMilieux_COMPUTERSANDEDUCATION, 0202 electrical engineering, electronic engineering, information engineering, Mathematics education, Task analysis, business, Set (psychology), Psychology, 0503 education, media_common
Abstract: In view of the deficiency of the traditional education mode of passive acceptance of students in college classrooms, this paper introduces OBE teaching concept and PBL teaching method. On the basis of understanding the current and future professional development needs, the teaching design is conducive to the cultivation of students' ability. Through the determination of training goals, the teaching goals is set and the PBL discussion based on practical engineering problems is introduced. The new teaching method can not only cover the teaching knowledge points, but also mobilize the enthusiasm and creativity of students, which is conducive to the cultivation of students' cooperative ability and innovation ability, and achieve better teaching results.
Published: 2021
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48. Simulation and Analyses of a Novel Air-conditioning Solution for Improving Energy Saving in a Data Room

Author: Cai Liang, Li Tong, and zhang xiao
Subjects: lcsh:GE1-350, business.industry, Airflow, 0211 other engineering and technologies, Refrigeration, ComputerApplications_COMPUTERSINOTHERSYSTEMS, 02 engineering and technology, Energy consumption, 010501 environmental sciences, Modular design, 01 natural sciences, Automotive engineering, Software, Drag, Air conditioning, Environmental science, 021108 energy, business, Energy (signal processing), lcsh:Environmental sciences, 0105 earth and related environmental sciences
Abstract: In view of the feature of long airflow path, high wind resistance, and large area of refrigeration equipment in traditional data room, a new type of under-floor modular air conditioner and its corresponding new air conditioning solution for data room is proposed in this paper. The mathematical and physical model of the new solution for data room is established through a computational fluid simulation software and compared with two mainstream air conditioning solutions. Meanwhile, the impact of these three different air conditioning solutions on the temperature field, airflow field and energy consumption are analysed. The results show that the new type air conditioning solution for data room not only can be used to improve the distribution of temperature and airflow in the data room, but also can greatly reduce the energy consumption of the system.
Published: 2021

49. Guidelines for the use and interpretation of assays for monitoring autophagy (4th edition) 1

Author: Klionsky, Daniel, Abdel-Aziz, Amal Kamal, Abdelfatah, Sara, Abdellatif, Mahmoud, Abdoli, Asghar, Abel, Steffen, Abeliovich, Hagai, Abildgaard, Marie, Abudu, Yakubu Princely, Acevedo-Arozena, Abraham, Adamopoulos, Iannis, Adeli, Khosrow, Adolph, Timon, Adornetto, Annagrazia, Aflaki, Elma, Agam, Galila, Agarwal, Anupam, Aggarwal, Bharat, Agnello, Maria, Agostinis, Patrizia, Agrewala, Javed, Agrotis, Alexander, Aguilar, Patricia, Ahmad, S Tariq, Ahmed, Zubair, Ahumada-Castro, Ulises, Aits, Sonja, Aizawa, Shu, Akkoc, Yunus, Akoumianaki, Tonia, Akpinar, Hafize Aysin, Al-Abd, Ahmed, Al-Akra, Lina, Al-Gharaibeh, Abeer, Alaoui-Jamali, Moulay, Alberti, Simon, Alcocer-Gómez, Elísabet, Alessandri, Cristiano, Ali, Muhammad, Alim Al-Bari, M Abdul, Aliwaini, Saeb, Alizadeh, Javad, Almacellas, Eugènia, Almasan, Alexandru, Alonso, Alicia, Alonso, Guillermo, Altan-Bonnet, Nihal, Altieri, Dario, Álvarez, Élida, Alves, Sara, Alves Da Costa, Cristine, Alzaharna, Mazen, Amadio, Marialaura, Amantini, Consuelo, Amaral, Cristina, Ambrosio, Susanna, Amer, Amal, Ammanathan, Veena, An, Zhenyi, Andersen, Stig, Andrabi, Shaida, Andrade-Silva, Magaiver, Andres, Allen, Angelini, Sabrina, Ann, David, Anozie, Uche, Ansari, Mohammad, Antas, Pedro, Antebi, Adam, Antón, Zuriñe, Anwar, Tahira, Apetoh, Lionel, Apostolova, Nadezda, Araki, Toshiyuki, Araki, Yasuhiro, Arasaki, Kohei, Araújo, Wagner, Araya, Jun, Arden, Catherine, Arévalo, Maria-Angeles, Arguelles, Sandro, Arias, Esperanza, Arikkath, Jyothi, Arimoto, Hirokazu, Ariosa, Aileen, Armstrong-James, Darius, Arnauné-Pelloquin, Laetitia, Aroca, Angeles, Arroyo, Daniela, Arsov, Ivica, Artero, Rubén, Asaro, Dalia Maria Lucia, Aschner, Michael, Ashrafizadeh, Milad, Ashur-Fabian, Osnat, Atanasov, Atanas, Au, Alicia, Auberger, Patrick, Auner, Holger, Aurelian, Laure, Autelli, Riccardo, Avagliano, Laura, Ávalos, Yenniffer, Aveic, Sanja, Aveleira, Célia Alexandra, Avin-Wittenberg, Tamar, Aydin, Yucel, Ayton, Scott, Ayyadevara, Srinivas, Azzopardi, Maria, Baba, Misuzu, Backer, Jonathan, Backues, Steven, Bae, Dong-Hun, Bae, Ok-Nam, Bae, Soo Han, Baehrecke, Eric, Baek, Ahruem, Baek, Seung-Hoon, Baek, Sung Hee, Bagetta, Giacinto, Bagniewska-Zadworna, Agnieszka, Bai, Hua, Bai, Jie, Bai, Xiyuan, Bai, Yidong, Bairagi, Nandadulal, Baksi, Shounak, Balbi, Teresa, Baldari, Cosima, Balduini, Walter, Ballabio, Andrea, Ballester, Maria, Balazadeh, Salma, Balzan, Rena, Bandopadhyay, Rina, Banerjee, Sreeparna, Banerjee, Sulagna, Bánréti, Ágnes, Bao, Yan, Baptista, Mauricio, Baracca, Alessandra, Barbati, Cristiana, Bargiela, Ariadna, Barilà, Daniela, Barlow, Peter, Barmada, Sami, Barreiro, Esther, Barreto, George, Bartek, Jiri, Bartel, Bonnie, Bartolome, Alberto, Barve, Gaurav, Basagoudanavar, Suresh, Bassham, Diane, Bast, Robert, Basu, Alakananda, Batoko, Henri, Batten, Isabella, Baulieu, Etienne, Baumgarner, Bradley, Bayry, Jagadeesh, Beale, Rupert, Beau, Isabelle, Beaumatin, Florian, Bechara, Luiz, Beck, George, Beers, Michael, Begun, Jakob, Behrends, Christian, Behrens, Georg, Bei, Roberto, Bejarano, Eloy, Bel, Shai, Behl, Christian, Belaid, Amine, Belgareh-Touzé, Naïma, Bellarosa, Cristina, Belleudi, Francesca, Belló Pérez, Melissa, Bello-Morales, Raquel, Beltran, Jackeline Soares de Oliveira, Beltran, Sebastián, Benbrook, Doris Mangiaracina, Bendorius, Mykolas, Benitez, Bruno, Benito-Cuesta, Irene, Bensalem, Julien, Berchtold, Martin, Berezowska, Sabina, Bergamaschi, Daniele, Bergami, Matteo, Bergmann, Andreas, Berliocchi, Laura, Berlioz-Torrent, Clarisse, Bernard, Amélie, Berthoux, Lionel, Besirli, Cagri, Besteiro, Sebastien, Betin, Virginie, Beyaert, Rudi, Bezbradica, Jelena, Bhaskar, Kiran, Bhatia-Kissova, Ingrid, Bhattacharya, Resham, Bhattacharya, Sujoy, Bhattacharyya, Shalmoli, Bhuiyan, Md Shenuarin, Bhutia, Sujit Kumar, Bi, Lanrong, Bi, Xiaolin, Biden, Trevor, Bijian, Krikor, Billes, Viktor, Binart, Nadine, Bincoletto, Claudia, Birgisdottir, Asa, Bjorkoy, Geir, Blanco, Gonzalo, Blas-Garcia, Ana, Blasiak, Janusz, Blomgran, Robert, Blomgren, Klas, Blum, Janice, Boada-Romero, Emilio, Boban, Mirta, Boesze-Battaglia, Kathleen, Boeuf, Philippe, Boland, Barry, Bomont, Pascale, Bonaldo, Paolo, Bonam, Srinivasa Reddy, Bonfili, Laura, Bonifacino, Juan, Boone, Brian, Bootman, Martin, Bordi, Matteo, Borner, Christoph, Bornhauser, Beat, Borthakur, Gautam, Bosch, Jürgen, Bose, Santanu, botana, luis, Botas, Juan, Boulanger, Chantal, Boulton, Michael, Bourdenx, Mathieu, Bourgeois, Benjamin, Bourke, Nollaig, Bousquet, Guilhem, Boya, Patricia, Bozhkov, Peter, Bozi, Luiz, Bozkurt, Tolga, Brackney, Doug, Brandts, Christian, Braun, Ralf, Braus, Gerhard, Bravo-Sagua, Roberto, Bravo-San Pedro, José, Brest, Patrick, Bringer, Marie-Agnès, Briones-Herrera, Alfredo, Broaddus, V Courtney, Brodersen, Peter, Brodsky, Jeffrey, Brody, Steven, Bronson, Paola, Bronstein, Jeff, Brown, Carolyn, Brown, Rhoderick, Brum, Patricia, Brumell, John, Brunetti-Pierri, Nicola, Bruno, Daniele, Bryson-Richardson, Robert, 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Sylvie, Giustiniani, Julien, Gluschko, Alexander, Goder, Veit, Goginashvili, Alexander, Golab, Jakub, Goldstone, David, Golebiewska, Anna, Gomes, Luciana, Gomez, Rodrigo, Gómez-Sánchez, Rubén, Gomez-Puerto, Maria Catalina, Gomez-Sintes, Raquel, Gong, Qingqiu, Goni, Felix, González-Gallego, Javier, Gonzalez-Hernandez, Tomas, Gonzalez-Polo, Rosa, Gonzalez-Reyes, Jose, González-Rodríguez, Patricia, Goping, Ing Swie, Gorbatyuk, Marina, Gorbunov, Nikolai, Görgülü, Kıvanç, Gorojod, Roxana, Gorski, Sharon, Goruppi, Sandro, Gotor, Cecilia, Gottlieb, Roberta, Gozes, Illana, Gozuacik, Devrim, Graef, Martin, Gräler, Markus, Granatiero, Veronica, Grasso, Daniel, Gray, Joshua, Green, Douglas, Greenhough, Alexander, Gregory, Stephen, Griffin, Edward, Grinstaff, Mark, Gros, Frederic, Grose, Charles, Gross, Angelina, Gruber, Florian, Grumati, Paolo, Grune, Tilman, Gu, Xueyan, Guan, Jun-Lin, Guardia, Carlos, Guda, Kishore, Guerra, Flora, Guerri, Consuelo, Guha, Prasun, Guillén, Carlos, Gujar, Shashi, 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Chengyu, Liang, Qiangrong, Liang, Weicheng, Liang, Yongheng, Liang, YongTian, Liao, Guanghong, Liao, Lujian, Liao, Mingzhi, Liao, Yung-Feng, Librizzi, Mariangela, Lie, Pearl, Lilly, Mary, Lim, Hyunjung, Lima, Thania, Limana, Federica, Lin, Chao, Lin, Chih-Wen, Lin, Dar-Shong, Lin, Fu-Cheng, Lin, Jiandie, Lin, Kurt, Lin, Kwang-Huei, Lin, Liang-Tzung, LIN, Pei-Hui, Lin, Qiong, Lin, Shaofeng, Lin, Su-Ju, Lin, Wenyu, Lin, Xueying, Lin, Yao-Xin, Lin, Yee-Shin, Linden, Rafael, Lindner, Paula, Ling, Shuo-Chien, Lingor, Paul, Linnemann, Amelia, Liou, Yih-Cherng, Lipinski, Marta, Lipovšek, Saška, Lira, Vitor, Lisiak, Natalia, Liton, Paloma, Liu, Chao, Liu, Ching-Hsuan, Liu, Chun-Feng, Liu, Cui Hua, Liu, Fang, Liu, Hao, Liu, Hsiao-Sheng, Liu, Hua-feng, Liu, Huifang, Liu, Jia, Liu, Jing, Liu, Julia, Liu, Leyuan, Liu, Longhua, Liu, Meilian, Liu, Qin, Liu, Wei, Liu, Wende, Liu, Xiao-Hong, Liu, Xiaodong, Liu, Xingguo, Liu, Xu, Liu, Xuedong, Liu, Yanfen, Liu, Yang, Liu, Yueyang, Liu, Yule, 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Jiangang, Shen, Ming, Shen, Weili, Shen, Zheni, Sheng, Rui, Sheng, Zhi, Sheng, Zu-Hang, Shi, Jianjian, Shi, Xiaobing, Shi, Ying-Hong, Shiba-Fukushima, Kahori, Shieh, Jeng-Jer, Shimada, Yohta, Shimizu, Shigeomi, Shimozawa, Makoto, Shintani, Takahiro, Shoemaker, Christopher, Shojaei, Shahla, Shoji, Ikuo, Shravage, Bhupendra, Shridhar, Viji, Shu, Chih-Wen, Shu, Hong-Bing, Shui, Ke, Shukla, Arvind, Shutt, Timothy, Sica, Valentina, Siddiqui, Aleem, Sierra, Amanda, Sierra-Torre, Virginia, Signorelli, Santiago, Sil, Payel, Silva, Bruno, Silva, Johnatas, Silva-Pavez, Eduardo, Silvente-Poirot, Sandrine, Simmonds, Rachel, Simon, Anna Katharina, Simon, Hans-Uwe, Simons, Matias, Singh, Anurag, Singh, Lalit, Singh, Rajat, Singh, Shivendra, Singh, Shrawan, Singh, Sudha, Singh, Sunaina, Singh, Surinder Pal, Sinha, Debasish, Sinha, Rohit Anthony, Sinha, Sangita, Sirko, Agnieszka, Sirohi, Kapil, Sivridis, Efthimios, Skendros, Panagiotis, Skirycz, Aleksandra, Slaninová, Iva, Smaili, Soraya, Smertenko, Andrei, Smith, Matthew, Soenen, Stefaan, Sohn, Eun Jung, Sok, Sophia, Solaini, Giancarlo, Soldati, Thierry, Soleimanpour, Scott, Soler, Rosa, Solovchenko, Alexei, Somarelli, Jason, Sonawane, Avinash, Song, Fuyong, Song, Hyun Kyu, Song, Ju-Xian, Song, Kunhua, Song, Zhiyin, Soria, Leandro, Sorice, Maurizio, Soukas, Alexander, Soukup, Sandra-Fausia, Sousa, Diana, Sousa, Nadia, Spagnuolo, Paul, Spector, Stephen, Srinivas Bharath, M., St Clair, Daret, Stagni, Venturina, Staiano, Leopoldo, Stalnecker, Clint, Stankov, Metodi, Stathopulos, Peter, Stefan, Katja, Stefan, Sven Marcel, Stefanis, Leonidas, Steffan, Joan, Steinkasserer, Alexander, Stenmark, Harald, Sterneckert, Jared, Stevens, Craig, Stoka, Veronika, Storch, Stephan, Stork, Björn, Strappazzon, Flavie, Strohecker, Anne Marie, Stupack, Dwayne, Su, Huanxing, Su, Ling-Yan, Su, Longxiang, Suarez-Fontes, Ana, Subauste, Carlos, Subbian, Selvakumar, Subirada, Paula, Sudhandiran, Ganapasam, Sue, Carolyn, Sui, Xinbing, Summers, Corey, Sun, Guangchao, Sun, Jun, SUN, Kang, Sun, Meng-xiang, Sun, Qiming, Sun, Yi, Sun, Zhongjie, Sunahara, Karen, Sundberg, Eva, Susztak, Katalin, Sutovsky, Peter, Suzuki, Hidekazu, Sweeney, Gary, Symons, J David, Sze, Stephen Cho Wing, Szewczyk, Nathaniel, Tabęcka-Łonczynska, Anna, Tabolacci, Claudio, Tacke, Frank, Taegtmeyer, Heinrich, Tafani, Marco, Tagaya, Mitsuo, Tai, Haoran, Tait, Stephen, Takahashi, Yoshinori, Takats, Szabolcs, Talwar, Priti, Tam, Chit, Tam, Shing Yau, Tampellini, Davide, Tamura, Atsushi, Tan, Chong Teik, Tan, Eng-King, Tan, Ya-Qin, Tanaka, Masaki, Tanaka, Motomasa, Tang, Daolin, Tang, Jingfeng, Tang, Tie-Shan, Tanida, Isei, Tao, Zhipeng, Taouis, Mohammed, Tatenhorst, Lars, Tavernarakis, Nektarios, Taylor, Allen, Taylor, Gregory, Taylor, Joan, Tchetina, Elena, Tee, Andrew, Tegeder, Irmgard, Teis, David, Teixeira, Natercia, Teixeira-Clerc, Fatima, Tekirdag, Kumsal, Tencomnao, Tewin, Tenreiro, Sandra, Tepikin, Alexei, Testillano, Pilar, Tettamanti, Gianluca, Tharaux, Pierre-Louis, Thedieck, Kathrin, Thekkinghat, Arvind, Thellung, Stefano, Thinwa, Josephine, Thirumalaikumar, V.P., Thomas, Sufi Mary, Thomes, Paul, Thorburn, Andrew, Thukral, Lipi, Thum, Thomas, Thumm, Michael, Tian, Ling, Tichy, Ales, Till, Andreas, Timmerman, Vincent, Titorenko, Vladimir, Todi, Sokol, Todorova, Krassimira, Toivonen, Janne, Tomaipitinca, Luana, Tomar, Dhanendra, Tomas-Zapico, Cristina, Tomić, Sergej, Tong, Benjamin Chun-Kit, Tong, Chao, Tong, Xin, Tooze, Sharon, Torgersen, Maria, Torii, Satoru, Torres-López, Liliana, Torriglia, Alicia, Towers, Christina, Towns, Roberto, Toyokuni, Shinya, Trajkovic, Vladimir, Tramontano, Donatella, Tran, Quynh-Giao, Travassos, Leonardo, Trelford, Charles, Tremel, Shirley, Trougakos, Ioannis, Tsao, Betty, Tschan, Mario, Tse, Hung-Fat, Tse, Tak Fu, Tsugawa, Hitoshi, Tsvetkov, Andrey, Tumbarello, David, Tumtas, Yasin, Tuñón, María, Turcotte, Sandra, Turk, Boris, Turk, Vito, Turner, Bradley, Tuxworth, Richard, Tyler, Jessica, Tyutereva, Elena, Uchiyama, Yasuo, Ugun-Klusek, Aslihan, Uhlig, Holm, Ułamek-Kozioł, Marzena, Ulasov, Ilya, Umekawa, Midori, Ungermann, Christian, Unno, Rei, Urbe, Sylvie, Uribe-Carretero, Elisabet, Üstün, Suayib, Uversky, Vladimir, Vaccari, Thomas, Vaccaro, Maria, Vahsen, Björn, Vakifahmetoglu-Norberg, Helin, Valdor, Rut, Valente, Maria, Valko, Ayelén, Vallee, Richard, Valverde, Angela, Van Den Berghe, Greet, van der Veen, Stijn, Van Kaer, Luc, van Loosdregt, Jorg, van Wijk, Sjoerd, Vandenberghe, Wim, Vanhorebeek, Ilse, Vannier-Santos, Marcos, Vannini, Nicola, Vanrell, M Cristina, Vantaggiato, Chiara, Varano, Gabriele, Varela-Nieto, Isabel, Varga, Máté, Vasconcelos, M Helena, Vats, Somya, Vavvas, Demetrios, Vega-Naredo, Ignacio, Vega-Rubin-de-Celis, Silvia, Velasco, Guillermo, Velázquez, Ariadna, Vellai, Tibor, Vellenga, Edo, Velotti, Francesca, Verdier, Mireille, Verginis, Panayotis, Vergne, Isabelle, Verkade, Paul, Verma, Manish, Verstreken, Patrik, Vervliet, Tim, Vervoorts, Jörg, Vessoni, Alexandre, Victor, Victor, Vidal, Michel, Vidoni, Chiara, Vieira, Otilia, Vierstra, Richard, Viganó, Sonia, Vihinen, Helena, Vijayan, Vinoy, Vila, Miquel, Vilar, Marçal, Villalba, José, Villalobo, Antonio, Villarejo-Zori, Beatriz, Villarroya, Francesc, Villarroya, Joan, Vincent, Olivier, Vindis, Cecile, Viret, Christophe, Viscomi, Maria Teresa, Visnjic, Dora, Vitale, Ilio, Vocadlo, David, Voitsekhovskaja, Olga, Volonté, Cinzia, Volta, Mattia, Vomero, Marta, Von Haefen, Clarissa, Vooijs, Marc, Voos, Wolfgang, Vucicevic, Ljubica, Wade-Martins, Richard, Waguri, Satoshi, Waite, Kenrick, Wakatsuki, Shuji, Walker, David, Walker, Mark, Walker, Simon, Walter, Jochen, Wandosell, Francisco, Wang, Bo, Wang, Chao-Yung, Wang, Chen, Wang, Chenran, Wang, Chenwei, Wang, Cun-Yu, Wang, Dong, Wang, Fangyang, Wang, Feng, Wang, Fengming, Wang, Guansong, Wang, Han, Wang, Hao, Wang, Hexiang, Wang, Hong-Gang, Wang, Jianrong, Wang, Jigang, Wang, Jiou, Wang, Jundong, Wang, Kui, Wang, Lianrong, Wang, Liming, Wang, Maggie Haitian, Wang, Meiqing, Wang, Nanbu, Wang, PengWei, Wang, PeiPei, Wang, Ping, Wang, Qing Jun, Wang, Qing, Wang, Qing Kenneth, Wang, Qiong, Wang, Wen-Tao, Wang, Wuyang, Wang, Xinnan, Wang, Xuejun, Wang, Yan, Wang, Yanchang, Wang, Yanzhuang, Wang, Yen-Yun, Wang, Yihua, Wang, Yipeng, Wang, Yu, wang, yuqi, Wang, Zhe, Wang, Zhenyu, Wang, Zhouguang, Warnes, Gary, Warnsmann, Verena, Watada, Hirotaka, Watanabe, Eizo, Watchon, Maxinne, Wawrzyńska, Anna, Weaver, Timothy, Wegrzyn, Grzegorz, Wehman, Ann, Wei, Huafeng, Wei, Lei, Wei, Taotao, Wei, Yongjie, Weiergräber, Oliver, Weihl, Conrad, Weindl, Günther, Weiskirchen, Ralf, Wells, Alan, Wen, Runxia, Wen, Xin, Werner, Antonia, Weykopf, Beatrice, Wheatley, Sally, Whitton, J Lindsay, Whitworth, Alexander, Wiktorska, Katarzyna, Wildenberg, Manon, Wileman, Tom, Wilkinson, Simon, Willbold, Dieter, Williams, Brett, Williams, Robin, Williams, Roger, Williamson, Peter, Wilson, Richard, Winner, Beate, Winsor, Nathaniel, Witkin, Steven, Wodrich, Harald, Woehlbier, Ute, Wollert, Thomas, Wong, Esther, Wong, Jack Ho, Wong, Richard, Wong, Vincent Kam Wai, Wong, W Wei-Lynn, Wu, An-Guo, Wu, Chengbiao, Wu, Jian, Wu, Junfang, Wu, Kenneth, Wu, Min, Wu, Shan-Ying, Wu, Shengzhou, Wu, Shu-Yan, Wu, Shufang, Wu, William, Wu, Xiaohong, Wu, Xiaoqing, Wu, Yao-Wen, Wu, Yihua, Xavier, Ramnik, Xia, Hongguang, Xia, Lixin, Xia, Zhengyuan, Xiang, Ge, Xiang, Jin, Xiang, Mingliang, Xiang, Wei, Xiao, Bin, Xiao, Guozhi, Xiao, Hengyi, Xiao, Hong-tao, Xiao, Jian, Xiao, Lan, Xiao, Shi, Xiao, Yin, Xie, Baoming, Xie, Chuan-Ming, Xie, Min, Xie, Yuxiang, Xie, Zhiping, Xie, Zhonglin, Xilouri, Maria, Xu, Congfeng, Xu, En, Xu, Haoxing, Xu, Jing, Xu, Jinrong, Xu, Liang, Xu, Wen Wen, Xu, Xiulong, Xue, Yu, Yakhine-Diop, Sokhna, Yamaguchi, Masamitsu, Yamaguchi, Osamu, Yamamoto, Ai, Yamashina, Shunhei, Yan, Shengmin, Yan, Shian-Jang, Yan, Zhen, Yanagi, Yasuo, Yang, Chuanbin, Yang, Dun-Sheng, Yang, Huan, Yang, Huang-Tian, Yang, Hui, Yang, Jin-Ming, Yang, Jing, Yang, Jingyu, Yang, Ling, Yang, Liu, Yang, Ming, Yang, Pei-Ming, Yang, Qian, Yang, Seungwon, Yang, Shu, Yang, Shun-Fa, Yang, Wannian, Yang, Wei Yuan, Yang, Xiaoyong, Yang, Xuesong, Yang, Yi, Yang, Ying, Yao, Honghong, Yao, Shenggen, Yao, Xiaoqiang, Yao, Yong-Gang, Yao, Yong-Ming, Yasui, Takahiro, Yazdankhah, Meysam, Yen, Paul, Yi, Cong, Yin, Xiao-Ming, Yin, Yanhai, Yin, Zhangyuan, Yin, Ziyi, Ying, Meidan, Ying, Zheng, Yip, Calvin, Yiu, Stephanie Pei Tung, Yoo, Young, Yoshida, Kiyotsugu, Yoshii, Saori, Yoshimori, Tamotsu, Yousefi, Bahman, Yu, Boxuan, Yu, Haiyang, Yu, Jun, Yu, Li, Yu, Ming-Lung, Yu, Seong-Woon, Yu, Victor, Yu, W Haung, Yu, Zhengping, Yu, Zhou, Yuan, Junying, Yuan, Ling-Qing, Yuan, Shilin, Yuan, Shyng-Shiou, Yuan, Yanggang, Yuan, Zengqiang, Yue, Jianbo, Yue, Zhenyu, Yun, Jeanho, Yung, Raymond, Zacks, David, Zaffagnini, Gabriele, Zambelli, Vanessa, Zanella, Isabella, Zang, Qun, Zanivan, Sara, Zappavigna, Silvia, Zaragoza, Pilar, Zarbalis, Konstantinos, Zarebkohan, Amir, Zarrouk, Amira, Zeitlin, Scott, Zeng, Jialiu, Zeng, Ju-deng, Žerovnik, Eva, Zhan, Lixuan, Zhang, Bin, Zhang, Donna, Zhang, Hanlin, Zhang, Hong, Zhang, Honghe, Zhang, Huafeng, Zhang, Huaye, Zhang, Hui, Zhang, Hui-Ling, Zhang, Jianbin, Zhang, Jianhua, Zhang, Jing-Pu, Zhang, Kalin, Zhang, Leshuai, Zhang, Lin, Zhang, Lisheng, Zhang, Lu, Zhang, Luoying, Zhang, Menghuan, Zhang, Peng, Zhang, Sheng, Zhang, Wei, Zhang, Xiangnan, Zhang, Xiao-Wei, Zhang, Xiaolei, Zhang, Xiaoyan, Zhang, Xin, Zhang, Xinxin, Zhang, Xu Dong, Zhang, Yang, Zhang, Yanjin, Zhang, Yi, Zhang, Ying-Dong, Zhang, Yingmei, Zhang, Yuan-Yuan, Zhang, Yuchen, Zhang, Zhe, Zhang, Zhengguang, Zhang, Zhibing, Zhang, Zhihai, Zhang, Zhiyong, Zhang, Zili, Zhao, Haobin, Zhao, Lei, Zhao, Shuang, Zhao, Tongbiao, Zhao, Xiao-Fan, Zhao, Ying, Zhao, Yongchao, Zhao, Yongliang, Zhao, Yuting, Zheng, Guoping, Zheng, Kai, Zheng, Ling, Zheng, Shizhong, Zheng, Xi-Long, Zheng, Yi, Zheng, Zu-Guo, Zhivotovsky, Boris, Zhong, Qing, Zhou, Ao, Zhou, Ben, Zhou, Cefan, ZHOU, Gang, Zhou, Hao, Zhou, Hong, Zhou, Hongbo, Zhou, Jie, Zhou, Jing, Zhou, Jiyong, Zhou, Kailiang, Zhou, Rongjia, Zhou, Xu-jie, Zhou, Yanshuang, Zhou, Yinghong, Zhou, Yubin, Zhou, Zheng-Yu, Zhou, Zhou, Zhu, Binglin, Zhu, Changlian, Zhu, Guo-Qing, Zhu, Haining, Zhu, Hongxin, Zhu, Hua, Zhu, Wei-Guo, Zhu, Yanping, Zhu, Yushan, Zhuang, Haixia, Zhuang, Xiaohong, Zientara-Rytter, Katarzyna, Zimmermann, Christine, Ziviani, Elena, Zoladek, Teresa, Zong, Wei-Xing, Zorov, Dmitry, Zorzano, Antonio, Zou, Weiping, Zou, Zhen, Zou, Zhengzhi, Zuryn, Steven, Zwerschke, Werner, Brand-Saberi, Beate, Dong, X Charlie, Kenchappa, Chandra Shekar, Li, Zuguo, Lin, Yong, Oshima, Shigeru, Rong, Yueguang, Sluimer, Judith, Stallings, Christina, Tong, Chun-Kit, Ahmad, S. Tariq, Alim Al-Bari, M. Abdul, Bechara, Luiz R.G., Behrens, Georg M.N., Bhuiyan, Md. Shenuarin, Broaddus, V. Courtney, Buchan, J. Ross, Burón, M. Isabel, Carter, A. Brent, Chan, Matthew T.V., Choi, Augustine M.K., D’Adamo, Stefania, D’Amelio, Marcello, D’Arcangelo, Daniela, D’Lugos, Andrew, D’Orazi, Gabriella, De Meyer, Guido R.Y., Delpino, M. Victoria, Distler, Jörg H.W., Dixon, Ian M.C., Dobson, Renwick C.J., 2nd Dorn, Gerald, Eissa, N. Tony, Engelsen, Agnete S.T., Fairlie, W. Douglas, Ferreira, Julio C.B., H.B., Ranjitha, Hanson, Phyllis I., Hejtmancik, J. Fielding, Ho, Idy H.T., Hobbs, G. Aaron, Hoet, Peter H.M., Huang, Michael L.H., Iyer, Anand Krishnan V., Johnson, Gail V.W., Joosten, Leo A.B., Karim, Md. Razaul, Kaufmann, Stefan H.E., Ko, Ben C.B., Leck, Lionel Y.W., Lima, Thania R.R., Livingston, J. Andrew, Martin, Alexandre P.J., Montes, L. Ruth, Murphy, J. Patrick, Ng, Charlene C.W., Nicolao, M. Celeste, O’Donovan, Tracey, O’Leary, Seónadh, O’Rourke, Eyleen, O’Sullivan, Mary, O’Sullivan, Timothy, Omary, M. Bishr, Pereira, Gustavo J.S., Ratnayaka, J. Arjuna, Riazuddin, S. Amer, Rouschop, Kasper M.A., Sanderson, J. Thomas, Scaglione, K. Matthew, Schapira, Anthony H.V., Scovassi, A. Ivana, St. Clair, Daret, Sunahara, Karen K.S., Symons, J. David, Triola, Gemma, van Wijk, Sjoerd J.L., Vanrell, M. Cristina, Vasconcelos, M. Helena, Whitton, J. Lindsay, Williams, Robin S.B., Wong, W. Wei-Lynn, Wu, William K.K., Yakhine-Diop, Sokhna M.S., Yu, W. Haung, Zhang, Kalin Y.B., Dong, X. Charlie, Ain Shams University [ASU], Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University [JGU], Medical University Graz, Centre de Recherche des Cordeliers [CRC (UMR_S_1138 / U1138)], Institut Pasteur d'Iran, Leibniz Institute of Plant Biochemistry [IPB], The University of Texas M.D. Anderson Cancer Center [Houston], Institut de pharmacologie moléculaire et cellulaire [IPMC], Lipides - Nutrition - Cancer [Dijon - U1231] [LNC], Centre méditerranéen de médecine moléculaire [C3M], Institut de Biologie Valrose [IBV], Petites Molécules de neuroprotection, neurorégénération et remyélinisation, Signalisation Hormonale, Physiopathologie Endocrinienne et Métabolique, Institut Cochin [IC UM3 (UMR 8104 / U1016)], Institut NeuroMyoGène [INMG], Paris-Centre de Recherche Cardiovasculaire [PARCC (UMR_S 970/ U970)], Marqueurs cardiovasculaires en situation de stress [MASCOT (UMR_S_942 / U942)], Institut de Recherche sur le Cancer et le Vieillissement [IRCAN], Centre de Recherche en Cancérologie de Marseille [CRCM], Centre for Integrative Biology - CBI [Inserm U964 - CNRS UMR7104 - IGBMC], Oncogenesis, Stress, Signaling [OSS], Institut Necker Enfants-Malades [INEM - UM 111 (UMR 8253 / U1151)], Institut de Biologie Intégrative de la Cellule [I2BC], Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte [M2iSH], Centre de Recherches en Cancérologie de Toulouse [CRCT], Physiopathologie et traitement des maladies du foie, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 [CIIL], Institut de Génétique et de Biologie Moléculaire et Cellulaire [IGBMC], Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] [BIO-PEROXIL], Centre de recherche sur l'Inflammation [CRI (UMR_S_1149 / ERL_8252 / U1149)], Unité de génétique et biologie des cancers [U830], Laboratoire d'Optique et Biosciences [LOB], Institut des Maladies Métaboliques et Casdiovasculaires [UPS/Inserm U1297 - I2MC], Différenciation et communication neuronale et neuroendocrine [DC2N], Institut de Recherche en Cancérologie de Montpellier [IRCM - U1194 Inserm - UM], Centre d'Immunologie de Marseille - Luminy [CIML], Physiopathologie et imagerie des troubles neurologiques [PhIND], Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée [LBFA], Imagine - Institut des maladies génétiques (IHU) [Imagine - U1163], Institut Mondor de Recherche Biomédicale [IMRB], Franco-czech Laboratory for clinical research on obesity, University of Michigan [Ann Arbor], University of Michigan System, Institut de pharmacologie moléculaire et cellulaire (IPMC), Centre National de la Recherche Scientifique (CNRS)-Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Université Côte d'Azur (UCA), Lipides - Nutrition - Cancer [Dijon - U1231] (LNC), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement, Centre méditerranéen de médecine moléculaire (C3M), Université Nice Sophia Antipolis (... - 2019) (UNS), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), Institut de Biologie Valrose (IBV), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA)-Centre National de la Recherche Scientifique (CNRS), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Sud - Paris 11 (UP11), Centre de Recherche des Cordeliers (CRC (UMR_S_1138 / U1138)), École pratique des hautes études (EPHE), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université de Paris (UP), Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM)-AP-HP Hôpital Bicêtre (Le Kremlin-Bicêtre), Nutrition, Métabolisme, Aquaculture (NuMéA), Université de Pau et des Pays de l'Adour (UPPA)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Institut Cochin (IC UM3 (UMR 8104 / U1016)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP), Institut NeuroMyoGène (INMG), Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM), Paris-Centre de Recherche Cardiovasculaire (PARCC - UMR-S U970), Hôpital Européen Georges Pompidou [APHP] (HEGP), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Institut de Recherche sur le Cancer et le Vieillissement (IRCAN), COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015 - 2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Centre des Sciences du Goût et de l'Alimentation [Dijon] (CSGA), Université de Bourgogne (UB)-AgroSup Dijon - Institut National Supérieur des Sciences Agronomiques, de l'Alimentation et de l'Environnement-Centre National de la Recherche Scientifique (CNRS)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de Recherche en Cancérologie de Marseille (CRCM), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Aix Marseille Université (AMU), Centre for Integrative Biology - CBI (Inserm U964 - CNRS UMR7104 - IGBMC), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institute of genetics and molecular and cellular biology-Centre National de la Recherche Scientifique (CNRS), Chemistry, Oncogenesis, Stress and Signaling (COSS), Université de Rennes 1 (UR1), Université de Rennes (UNIV-RENNES)-Université de Rennes (UNIV-RENNES)-CRLCC Eugène Marquis (CRLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut Necker Enfants-Malades (INEM - UM 111 (UMR 8253 / U1151)), Unité de Nutrition Humaine (UNH), Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut de Biologie Intégrative de la Cellule (I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Microbes, Intestin, Inflammation et Susceptibilité de l'Hôte (M2iSH), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre de Recherche en Nutrition Humaine d'Auvergne (CRNH d'Auvergne)-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE)-Université Clermont Auvergne (UCA), Institut des Maladies Neurodégénératives [Bordeaux] (IMN), Université de Bordeaux (UB)-Centre National de la Recherche Scientifique (CNRS), Centre International de Recherche en Infectiologie - UMR (CIRI), École normale supérieure - Lyon (ENS Lyon)-Université Claude Bernard Lyon 1 (UCBL), Université de Lyon-Université de Lyon-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre de Recherches en Cancérologie de Toulouse (CRCT), Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Laboratoire de Physiologie et Génomique des Poissons (LPGP), Structure Fédérative de Recherche en Biologie et Santé de Rennes ( Biosit : Biologie - Santé - Innovation Technologique )-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Hôpital Paul Brousse-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Saclay, Centre d’Infection et d’Immunité de Lille - INSERM U 1019 - UMR 9017 - UMR 8204 (CIIL), Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Lille-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Centre National de la Recherche Scientifique (CNRS), Institut de Génétique et de Biologie Moléculaire et Cellulaire (IGBMC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA), Laboratoire Bio-PeroxIL. Biochimie du peroxysome, inflammation et métabolisme lipidique [Dijon] (BIO-PEROXIL), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Bourgogne Franche-Comté [COMUE] (UBFC), Centre de recherche sur l'Inflammation (CRI (UMR_S_1149 / ERL_8252 / U1149)), Institut Jean-Pierre Bourgin (IJPB), AgroParisTech-Université Paris-Saclay-Institut National de Recherche pour l’Agriculture, l’Alimentation et l’Environnement (INRAE), Unité de génétique et biologie des cancers (U830), Institut Curie [Paris]-Institut National de la Santé et de la Recherche Médicale (INSERM), Laboratoire d'Optique et Biosciences (LOB), École polytechnique (X)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Institut des Maladies Métaboliques et Cardiovasculaires (I2MC), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-Institut National de la Santé et de la Recherche Médicale (INSERM), Différenciation et communication neuronale et neuroendocrine (DC2N), Université de Rouen Normandie (UNIROUEN), Normandie Université (NU)-Normandie Université (NU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Institut de Recherche en Cancérologie de Montpellier (IRCM - U1194 Inserm - UM), CRLCC Val d'Aurelle - Paul Lamarque-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Montpellier (UM), Centre d'Immunologie de Marseille - Luminy (CIML), Aix Marseille Université (AMU)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie et imagerie des troubles neurologiques (PhIND), Université de Caen Normandie (UNICAEN), Laboratory of Fundamental and Applied Bioenergetics = Laboratoire de bioénergétique fondamentale et appliquée (LBFA), Université Grenoble Alpes (UGA)-Institut National de la Santé et de la Recherche Médicale (INSERM), Epithelial biology and disease - Liliane Bettencourt Chair of Developmental Biology (Equipe Inserm U1163), Imagine - Institut des maladies génétiques (IHU) (Imagine - U1163), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université de Paris (UP), Biomécanique cellulaire et respiratoire (BCR), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12)-Centre National de la Recherche Scientifique (CNRS), Charles University [Prague]-Institut National de la Santé et de la Recherche Médicale (INSERM), This work was supported by the National Institute of General Medical Sciences [GM131919]., Université Paris-Sud - Paris 11 (UP11)-Institut National de la Santé et de la Recherche Médicale (INSERM), Marqueurs cardiovasculaires en situation de stress (MASCOT (UMR_S_942 / U942)), Institut National de la Santé et de la Recherche Médicale (INSERM)-Groupe Hospitalier Saint Louis - Lariboisière - Fernand Widal [Paris], Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université de Paris (UP)-Université Sorbonne Paris Nord, Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Physiopathologie des Adaptations Nutritionnelles (PhAN), Université de Nantes (UN)-Institut National de la Recherche Agronomique (INRA), Département Plateforme (PF I2BC), Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS)-Commissariat à l'énergie atomique et aux énergies alternatives (CEA)-Université Paris-Saclay-Centre National de la Recherche Scientifique (CNRS), Institut Gustave Roussy (IGR), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO), Chinese Academy of Medical Sciences [Suzhou, Chine] (CAMS), Karolinska Institutet [Stockholm], Karolinska University Hospital [Stockholm], Department of Women's and Children's Health [Stockholm, Sweden], Centre National de la Recherche Scientifique (CNRS)-Centre Hospitalier Régional Universitaire [Lille] (CHRU Lille)-Université de Lille-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Pasteur de Lille, Réseau International des Instituts Pasteur (RIIP)-Réseau International des Instituts Pasteur (RIIP), Université de Strasbourg (UNISTRA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Centre National de la Recherche Scientifique (CNRS)-Institut National de la Santé et de la Recherche Médicale (INSERM)-École polytechnique (X), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Toulouse III - Paul Sabatier (UT3), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées, FHU OncoAge - Pathologies liées à l’âge [CHU Nice] (OncoAge), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA)-Institut de Pharmacologie Moléculaire et Cellulaire [UNIV Côte d'Azur] (UPMC), Institut Universitaire du Cancer de Toulouse - Oncopole (IUCT Oncopole - UMR 1037), Université Fédérale Toulouse Midi-Pyrénées-Université Fédérale Toulouse Midi-Pyrénées-CHU Toulouse [Toulouse]-Institut National de la Santé et de la Recherche Médicale (INSERM), Life Sciences Institute [Ann Arbor, MI, USA], University of Michigan System-University of Michigan System, European Institute of Oncology IRCCS [Milan, Italy] (EIO), Ain Shams University (ASU), Johannes Gutenberg - Universität Mainz = Johannes Gutenberg University (JGU), Université Paris sciences et lettres (PSL)-Université Paris sciences et lettres (PSL)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Sorbonne Université (SU)-Université Paris Cité (UPCité), Réseau International des Instituts Pasteur (RIIP), Leibniz Institute of Plant Biochemistry (IPB), Hebrew University of Jerusalem, Université Nice Sophia Antipolis (1965 - 2019) (UNS), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Université de Bourgogne (UB)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Institut Agro Dijon, Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro)-Institut national d'enseignement supérieur pour l'agriculture, l'alimentation et l'environnement (Institut Agro), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Côte d'Azur (UCA), COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-COMUE Université Côte d'Azur (2015-2019) (COMUE UCA)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Côte d'Azur (UCA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité), Paris-Centre de Recherche Cardiovasculaire (PARCC (UMR_S 970/ U970)), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Hôpitaux Universitaires Paris Ouest - Hôpitaux Universitaires Île de France Ouest (HUPO)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Assistance publique - Hôpitaux de Paris (AP-HP) (AP-HP)-Centre National de la Recherche Scientifique (CNRS)-Université Paris Cité (UPCité)-Université Sorbonne Paris Nord, Aix Marseille Université (AMU)-Institut Paoli-Calmettes, Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Fédération nationale des Centres de lutte contre le Cancer (FNCLCC)-Institut National de la Santé et de la Recherche Médicale (INSERM)-Centre National de la Recherche Scientifique (CNRS), Oncogenesis, Stress, Signaling (OSS), Institut des Maladies Métaboliques et Casdiovasculaires (UPS/Inserm U1297 - I2MC), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Grenoble Alpes (UGA), Institut National de la Santé et de la Recherche Médicale (INSERM)-Université Paris Cité (UPCité), Institut Mondor de Recherche Biomédicale (IMRB), Institut National de la Santé et de la Recherche Médicale (INSERM)-IFR10-Université Paris-Est Créteil Val-de-Marne - Paris 12 (UPEC UP12), Charles University [Prague] (CU)-Institut National de la Santé et de la Recherche Médicale (INSERM), Klionsky, D. 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C., Brodersen, P., Brodsky, J. L., Brody, S. L., Bronson, P. G., Bronstein, J. M., Brown, C. N., Brown, R. E., Brum, P. C., Brumell, J. H., Brunetti-Pierri, N., Bruno, D., Bryson-Richardson, R. J., Bucci, C., Buchrieser, C., Bueno, M., Buitrago-Molina, L. E., Buraschi, S., Buch, S., Buchan, J. R., Buckingham, E. M., Budak, H., Budini, M., Bultynck, G., Burada, F., Burgoyne, J. R., Buron, M. I., Bustos, V., Buttner, S., Butturini, E., Byrd, A., Cabas, I., Cabrera-Benitez, S., Cadwell, K., Cai, J., Cai, L., Cai, Q., Cairo, M., Calbet, J. A., Caldwell, G. A., Caldwell, K. A., Call, J. A., Calvani, R., Calvo, A. C., Calvo-Rubio Barrera, M., Camara, N. O. S., Camonis, J. H., Camougrand, N., Campanella, M., Campbell, E. M., Campbell-Valois, F. -X., Campello, S., Campesi, I., Campos, J. C., Camuzard, O., Cancino, J., Candido de Almeida, D., Canesi, L., Caniggia, I., Canonico, B., Canti, C., Cao, B., Caraglia, M., Carames, B., Carchman, E. 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E., Chung, H., Chung, K. P., Chung, S., Chung, S. -H., Chung, Y. -L., Cianfanelli, V., Ciechomska, I. A., Cifuentes, M., Cinque, L., Cirak, S., Cirone, M., Clague, M. J., Clarke, R., Clementi, E., Coccia, E. M., Codogno, P., Cohen, E., Cohen, M. M., Colasanti, T., Colasuonno, F., Colbert, R. A., Colell, A., Colic, M., Coll, N. S., Collins, M. O., Colombo, M. I., Colon-Ramos, D. A., Combaret, L., Comincini, S., Cominetti, M. R., Consiglio, A., Conte, A., Conti, F., Contu, V. R., Cookson, M. R., Coombs, K. M., Coppens, I., Corasaniti, M. T., Corkery, D. P., Cordes, N., Cortese, K., Costa, M. D. C., Costantino, S., Costelli, P., Coto-Montes, A., Crack, P. J., Crespo, J. L., Criollo, A., Crippa, V., Cristofani, R., Csizmadia, T., Cuadrado, A., Cui, B., Cui, J., Cui, Y., Culetto, E., Cumino, A. C., Cybulsky, A. V., Czaja, M. J., Czuczwar, S. J., D'Adamo, S., D'Amelio, M., D'Arcangelo, D., D'Lugos, A. C., D'Orazi, G., da Silva, J. A., Dafsari, H. S., Dagda, R. 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Subjects: 0301 basic medicine, Programmed cell death, Settore BIO/06, Autophagosome, Autolysosome, [SDV]Life Sciences [q-bio], lnfectious Diseases and Global Health Radboud Institute for Molecular Life Sciences [Radboudumc 4], Autophagy-Related Proteins, Review, Computational biology, [SDV.BC]Life Sciences [q-bio]/Cellular Biology, Biology, Settore MED/04, 03 medical and health sciences, stress, Chaperone-mediated autophagy, ddc:570, Autophagy, LC3, Animals, Humans, cancer, Settore BIO/10, flux, lysosome, macroautophagy, neurodegeneration, phagophore, vacuole, Set (psychology), Molecular Biology, 030102 biochemistry & molecular biology, business.industry, Interpretation (philosophy), Autophagosomes, Cell Biology, Multicellular organism, 030104 developmental biology, Knowledge base, Biological Assay, Lysosomes, business, Biomarkers, [SDV.MHEP]Life Sciences [q-bio]/Human health and pathology
Abstract: Contains fulltext : 232759.pdf (Publisher’s version ) (Closed access) In 2008, we published the first set of guidelines for standardizing research in autophagy. Since then, this topic has received increasing attention, and many scientists have entered the field. Our knowledge base and relevant new technologies have also been expanding. Thus, it is important to formulate on a regular basis updated guidelines for monitoring autophagy in different organisms. Despite numerous reviews, there continues to be confusion regarding acceptable methods to evaluate autophagy, especially in multicellular eukaryotes. Here, we present a set of guidelines for investigators to select and interpret methods to examine autophagy and related processes, and for reviewers to provide realistic and reasonable critiques of reports that are focused on these processes. These guidelines are not meant to be a dogmatic set of rules, because the appropriateness of any assay largely depends on the question being asked and the system being used. Moreover, no individual assay is perfect for every situation, calling for the use of multiple techniques to properly monitor autophagy in each experimental setting. Finally, several core components of the autophagy machinery have been implicated in distinct autophagic processes (canonical and noncanonical autophagy), implying that genetic approaches to block autophagy should rely on targeting two or more autophagy-related genes that ideally participate in distinct steps of the pathway. Along similar lines, because multiple proteins involved in autophagy also regulate other cellular pathways including apoptosis, not all of them can be used as a specific marker for bona fide autophagic responses. Here, we critically discuss current methods of assessing autophagy and the information they can, or cannot, provide. Our ultimate goal is to encourage intellectual and technical innovation in the field.
Published: 2021
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50. Calculation and Analysis of Aircraft Pollutant Emission Based on Time Wake Separation Mode under Coastal Airport and Headwind Conditions

Author: Zhang Heng-Heng, Zhang Xiao-Lei, Wu Tian-Yi, and Pan Weijun
Subjects: Pollutant, Economics and Econometrics, TA1001-1280, Article Subject, Aviation, business.industry, Strategy and Management, Mechanical Engineering, Separation (aeronautics), Mode (statistics), Civil aviation, Environmental pollution, Automotive engineering, Computer Science Applications, Transportation engineering, Ground speed, Automotive Engineering, Fuel efficiency, Environmental science, business, Transportation and communications, HE1-9990
Abstract: During the final approach, the headwind leads to a reduction of landing rate, which affects the achieved capacity and the predictability of operation, time, fuel efficiency, and environmental pollution. Under headwind conditions, ground speed decrease results in increased flight time. Time-based separation (TBS) changes the separation rule of the final approach, which changes the distance separation between two aircrafts into a time separation. This paper introduces the time-based separation (TBS) based on the distance-based separation (DBS). According to the aircraft landing schedule of each airport, the ICAO (International Civil Aviation Organization) aircraft engine emission database, Boeing Fuel Flow Method 2 (BFFM2), and meteorological data of Pu-dong airport, this study uses the modified P3-T3 aviation pollutant emission model to calculate, respectively, the fuel consumption and pollutant emissions based on distance separation mode and time separation mode. According to the calculation results, TBS operation mode can save 32.52%, 19.12%, and 30.41% fuel, reduce 28.93%, 17.9%, and 29.29% CO, 31.02%, 19.36%, and 33.78% HC, 30.85%, 16.42%, and 28.67% NOx, respectively, compared with the DBS operation mode at three stages of the day. It ends that TBS has an obvious optimization effect on fuel consumption and pollutant emission compared with DBS from data.
Published: 2021
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