Search

A patent has been issued for systems designed to monitor and apply electrical currents in an organ perfusion system by Transmedics Inc. The invention aims to improve organ preservation techniques by extending the time an organ can be maintained ex-vivo in a healthy state, allowing for better evaluation and potential repair of defects. The system includes electrodes placed on the explanted heart to measure electrical activity and deliver defibrillation energy, addressing issues associated with conventional electrode systems. This innovation could enhance transplant outcomes, enlarge donor and recipient pools, and provide benefits beyond organ transplantation. [Extracted from the article]

Medhub Ltd. has been issued a patent for automated analysis of image data to determine fractional flow reserve. The patent aims to provide a fully automated solution for vessel analysis based on image data, eliminating the need for user input regarding the location of the vessel or pathology. The system can detect and track pathologies in vessels from different angles, allowing for improved automated solutions and facilitating user interaction with the system. The patent was filed on September 7, 2020, and published online on January 28, 2025, with inventors Bruch-El, Or, Goldman, David, and Kassel, Alexandre. [Extracted from the article]

Researchers have submitted a patent application titled "Grasping For Tissue Repair" to the USPTO, focusing on methods, devices, and systems for endovascular, percutaneous, or minimally invasive surgical treatment of bodily tissues, particularly heart valves. The patent application by inventor Michael F. Wei, assigned to Abbott Cardiovascular Systems Inc., aims to address mitral valve regurgitation through innovative techniques that avoid the need for open heart surgery. The application describes a fixation device designed for intravascular delivery to treat mitral valve defects in human patients, emphasizing the importance of tissue approximation and engagement for effective repair. [Extracted from the article]

A patent application titled "Ultrasound Imaging And Backscatter System And Method" by inventors Masters and Stoppenhagen, assigned to SoundCath Inc., aims to address limitations in existing imaging technologies for cardiovascular diseases. The application describes an ultrasound imaging system with a Piezoelectric Micromachined Ultrasonic Transducer (pMUT) array for improved myocardial structure assessment. The system includes a catheter, electronic flex cable, and imaging device for noninvasive diagnosis and risk assessment. The invention also discusses advancements in ablation catheters and a cryoablation method for efficient ablation. [Extracted from the article]

The patent issued by Twelve Inc. focuses on hydraulic systems for delivering prosthetic heart valve devices, specifically addressing conditions affecting mitral valves such as regurgitation, prolapse, and stenosis. The technology aims to provide less invasive approaches for mitral valve replacement, which is more challenging due to the unique anatomical obstacles of the mitral valve compared to the aortic valve. The system described in the patent involves an elongated catheter body with a delivery capsule that can be hydraulically driven to deploy the prosthetic heart valve device into the heart of a patient. [Extracted from the article]

A patent has been issued for an RF ablation catheter designed for septal reduction therapy with a cooling effect by Tau Medical Inc. The catheter is intended for treating conditions such as hypertrophic cardiomyopathy and ventricular tachycardia by applying RF energy to the interventricular septum. The design includes features to prevent tissue carbonization and facilitate RF transmission, widening the range of cauterization. [Extracted from the article]

A patent application titled "Rvot Wire Capturing (Rwc) System In Mitral Valve Cerclage Annuloplasty" by inventor June-Hong Kim from Busan, South Korea, and assigned to Tau Medical Inc., describes a minimally invasive, percutaneous method for treating mitral regurgitation. The method involves guiding a cerclage wire through the heart's safe zone to repair the mitral valve without open-heart surgery, reducing risks and complications associated with traditional treatments. The patent application outlines specific devices and techniques to ensure proper positioning of the cerclage wire and prevent damage to critical cardiac structures during the procedure. [Extracted from the article]

A patent has been issued for a mitral valve annuloplasty device with a twisted anchor, designed to reshape tissue adjacent to vessels in the heart to treat mitral valve regurgitation. The device, developed by Cardiac Dimensions Pty. Ltd., aims to provide a minimally invasive alternative to traditional surgical procedures for patients with mitral valve issues. By deploying anchors and a support structure in the coronary sinus, the device can reshape mitral valve tissue to reduce regurgitation, offering a potentially less invasive treatment option for patients. [Extracted from the article]

A patent has been issued for rotational atherectomy devices and methods by Cardio Flow Inc., focusing on treating atherosclerotic blockages in blood vessels. The invention involves using abrasive elements to abrade and breakdown stenotic lesions in arteries, improving blood flow. The patent details methods for rotational atherectomy in pedal arteries below the ankle and coronary branch arteries of the heart, offering options for efficiently treating a variety of arterial sites during a single procedure. [Extracted from the article]

A patent application titled "Vessel Scoring Device" by inventors Hemerick and WasDyke, assigned to Boston Scientific Scimed Inc., focuses on medical devices for treating occluded or narrowed blood vessels. The device includes an inflatable balloon with a blade for cutting or scoring stenosis to reduce re-stenosis post-treatment. The patent application details various designs and methods for manufacturing medical device structures to enhance angioplasty treatments. This innovation aims to improve cardiovascular surgical procedures and healthcare technology. [Extracted from the article]

A patent was issued for an electrode application instrument designed by Marcus Braun and assigned to Tuebingen Scientific Medical GmbH. The instrument aims to simplify and ensure the safe application of electrodes to the heart muscle, addressing challenges in accuracy and safety during implantation procedures. The design features a unique effector with two branches that can be moved towards each other in a forceps-like manner, providing grooves to securely hold the electrode in place. The instrument is part of the minimally invasive type of surgical tools, enhancing precision and safety in cardiac procedures. [Extracted from the article]

A patent was issued to Abbott Cardiovascular Systems Inc. for tissue fixation devices and methods, specifically focusing on repairing heart valves, such as the mitral valve, through minimally invasive procedures. The patent describes methods and devices for gripping tissue in a tissue repair and fixation procedure, emphasizing the need for elasticity and durability in tissue fixation devices. The patent aims to provide alternative and additional methods for tissue fixation that maintain flexibility and mobility while reducing the risk of premature device failure. [Extracted from the article]

Walk Vascular LLC, based in Irvine, California, has been granted patent number 12171444 for systems and methods aimed at removing blood and thrombotic material. The patent, filed in August 2022 and published online in December 2024, focuses on medical devices and methods for aspiration and thrombectomy. The invention addresses limitations of existing devices by offering a system that includes an aspiration catheter, a supply lumen, an aspiration lumen, and a combined hydraulic and electrical control for aspirating thrombus. The patent aims to improve the efficiency and effectiveness of thrombus removal procedures in the field of cardiovascular health. [Extracted from the article]

A patent application titled "Stabilizer For A Medical Delivery System" was published online by inventors from various locations in California and assigned to Evalve Inc. The application focuses on medical devices for endovascular, percutaneous, or minimally invasive surgical treatment of bodily tissues, particularly heart valves. The invention aims to simplify and control the movement of delivery systems during heart valve repair procedures, providing stabilizers to support external components of the system. The patent application outlines a stabilizer for a medical delivery system and a system including the stabilizer, emphasizing the need for improved devices and systems for tissue repair beyond heart valves. [Extracted from the article]

Researchers NAKADA, Masakazu, NAMIMA, Satoshi, and YAMANAKA, Nobuyoshi have submitted a patent application for a heart model that aims to improve surgical and treatment training for medical professionals. The heart model includes a deformable simulated ventricle and a twist generation portion that regulates deformation to generate a twist during expansion and contraction. This innovation by Asahi Intecc Co. Ltd. could enhance medical education and practice in the field of cardiology. [Extracted from the article]

A patent has been issued to Myocardial Solutions Inc. for a method that allows for rapid, quantitative evaluations of heart function using strain measurements from MRI. This method aims to provide objective assessments of heart muscle functionality, indicating weakness and whether it is reversible. By reducing the time patients spend inside the MRI magnet bore to under five minutes, the method offers a comprehensive assessment of heart muscle functionality with high accuracy. The patent focuses on improving medical imaging technologies, particularly MRI, to enhance the diagnosis of conditions like heart disease. [Extracted from the article]

A patent was issued for a method developed by inventor Gil Hacohen from Cardiovalve Ltd. The method involves using a collapsible prosthetic valve for implantation in a patient's native atrioventricular valve, such as the mitral or tricuspid valve, to address regurgitation caused by ischemic heart disease. The patent details a method for implanting the prosthetic valve using a single elongate element and catheter, providing a minimally-invasive treatment option for heart valve dysfunction. The patent aims to improve cardiac output and prevent further damage to the heart due to volume and pressure overload. [Extracted from the article]

A patent has been issued for systems and methods for the removal of blood and thrombotic material by Walk Vascular LLC. The invention focuses on aspiration and thrombectomy devices to address limitations in existing devices for removing thrombotic material. The patent details various embodiments and methods for aspirating thrombus, providing a detailed description of the technology and its potential applications in the medical field. [Extracted from the article]

Genetesis has launched the CardioFlux Membership program, offering a new way to monitor heart health through regular heart scans at CardioFlux Imaging Institutes. The program aims to revolutionize preventive cardiac care and eliminate heart disease by providing personalized and effective preventive approaches. Genetesis' flagship device, CardioFlux MCG, measures cardiac function noninvasively and has received FDA clearance, with ongoing clinical trials to explore its utility in diagnostic and preventive cardiac applications. [Extracted from the article]

Researchers have submitted a patent application titled "Compounds And Methods For Reducing Pln Expression" to the USPTO, focusing on targeting phospholamban (PLN) to manage cardiac dysfunction in heart failure and associated conditions. The patent application by inventors from Ionis Pharmaceuticals Inc. aims to reduce PLN RNA levels and phospholamban expression in subjects with cardiomyopathy, arrhythmia, or heart failure using modified oligonucleotides and compounds. The application highlights the importance of intracellular calcium regulation in cardiac muscle function and offers potential therapeutic strategies for improving contractile function and managing symptoms of heart-related disorders. [Extracted from the article]

The patent issued for systems and methods for the removal of blood and thrombotic material by Walk Vascular LLC in Irvine, California, focuses on the development of aspiration and thrombectomy devices. These devices aim to address limitations in existing technologies by providing more efficient and effective methods for removing thrombotic material from blood vessels. The patent outlines various embodiments of the invention, including systems for aspirating thrombus and delivering drugs intravascularly, with a focus on improving performance and reducing risks associated with current devices. [Extracted from the article]

A patent application titled "Cutting Blade With Shortened Terminal Blade Segments" by inventor Gordon John Kocur has been published online by Boston Scientific Scimed Inc. The invention aims to address issues related to coronary artery disease and blocked blood vessels by using blade-equipped angioplasty balloons to reduce re-stenosis and trauma during treatment. The patent application describes various designs and methods for manufacturing medical devices with blade members that can flex to treat lesions within blood vessels. This innovation could potentially enhance angioplasty treatments and improve patient outcomes in cardiovascular surgical procedures. [Extracted from the article]

A patent application titled "Variable Stiffness Delivery System for Edge-To-Edge Transcatheter Valve Repair and Methods of Making and Using Same" was published online by the USPTO on November 21, 2024. The inventors, Abunassar and Van Hoven, developed an interventional tool that can transition between different stiffness states to aid in mitral valve regurgitation treatment. This technology aims to improve heart function and reduce the need for open-heart surgery, potentially benefiting patients at risk of heart failure. The patent application was filed by Evalve Inc. and focuses on innovative methods for transcatheter delivery of implants to correct heart valve issues. [Extracted from the article]

A patent has been issued for tissue grasping devices and related methods by Evalve Inc., focusing on minimally invasive surgical treatment of bodily tissues, particularly heart valves. Mitral valve regurgitation, a condition affecting heart function, is highlighted as a key area of concern. The patent describes innovative tissue gripping devices and systems designed to address the challenges associated with tissue fixation treatments, offering alternative methods for improved elasticity and durability. The patent outlines various embodiments and methods for tissue gripping, fixation systems, and manufacturing processes, aiming to enhance the effectiveness and safety of treatments for heart valve disorders. [Extracted from the article]

A patent was issued to Abbott Cardiovascular Systems Inc. for a device designed to treat mitral valve defects in human patients. The device aims to repair heart valves through minimally invasive procedures, specifically targeting mitral valve regurgitation. By using a fixation implant, the device can hold adjacent segments of valve leaflets together, potentially reducing mitral valve regurgitation and avoiding the need for open-heart surgery. This innovation represents a significant advancement in cardiovascular healthcare technology. [Extracted from the article]

The patent issued for a tether attachment for a collapsible and expandable prosthetic heart valve aims to stabilize the valve within a patient's native annulus, particularly focusing on the mitral valve. The invention by Tendyne Holdings Inc. involves a low-profile prosthetic heart valve design that securely anchors within the native mitral valve annulus without obstructing blood flow to the Left Ventricular Outflow Tract (LVOT). By utilizing a tether connector and apical pad, the prosthetic heart valve can be implanted and secured effectively, addressing challenges related to paravalvular leakage and blood flow obstruction. [Extracted from the article]

A patent application by Abbott Cardiovascular Systems Inc. for a "System For Fixation of Leaflets Of A Heart Valve" has been made available online. The invention aims to provide improved methods, devices, and systems for repairing mitral and other cardiac valves, focusing on minimally invasive approaches. The patent application details a system for fixing tissue, including implantable fixation devices and delivery devices, to treat conditions such as mitral valve regurgitation. The system allows for independent movement of the fixation elements and is adaptable for various therapeutic procedures in different anatomical regions. [Extracted from the article]

A patent was issued for methods and devices for tissue grasping and assessment by Evalve Inc. The invention focuses on repairing valves of the heart, particularly the mitral valve, to treat regurgitation and improve heart function. The patent describes devices, systems, and methods for stabilizing, grasping, assessing, and fixating tissues, specifically valve leaflets, in a minimally invasive manner to avoid the need for open heart surgery. The goal is to provide more effective and efficient treatments for cardiac valve regurgitation. [Extracted from the article]

The patent application titled "Independent Proximal Element Actuation Methods" by inventors Abunassar, Chad et al. focuses on innovative methods, devices, and systems for minimally invasive surgical treatment of bodily tissues, particularly heart valves. The application aims to improve the repair of mitral and other cardiac valves without the need for open chest access, providing features for easier delivery, repositioning, and optional removal of fixation devices. The system includes an implantable fixation device, a delivery device with a catheter, and a handle with proximal element line handles and an interlock mechanism for simultaneous actuation. The application emphasizes the importance of enhanced attachment mechanisms and evaluation methods for optimal placement of fixation devices. [Extracted from the article]

Boston Scientific Scimed Inc. has been issued a patent for a mapping assembly for a cryogenic balloon catheter system. The patent aims to improve the treatment of cardiac arrhythmias, particularly atrial fibrillation, by using cryoablation procedures. The invention involves a catheter with a cryoballoon that can transition between deflated and inflated states, along with electrode arrays for mapping and ablation. This innovation is expected to enhance patient outcomes and facilitate real-time monitoring of cardiac tissue during procedures. [Extracted from the article]

A patent was issued for a catheter pump with a cannula and selectively positionable impeller blade by TC1 LLC. The invention aims to provide mechanical circulatory support to patients after a heart attack or cardiac event. The catheter pump can transition between a separated configuration and an operational configuration, allowing for easier insertion and reduced sheathing force. The patent details the design and functionality of the catheter pump, emphasizing the importance of reducing risks and improving patient outcomes in cardiac care. [Extracted from the article]

Asahi Intecc Co. Ltd. has been issued a patent for a heart model that includes a ventricle formation portion and a twist generation portion to simulate the expansion and contraction of the ventricle. The twist generation portion regulates the deformation of the ventricle formation portion to generate a twist during expansion. This patent aims to provide a simpler configuration for generating a twist in the heart model during surgical and treatment training. [Extracted from the article]

Evalve Inc. has been issued a patent for tissue cutting systems, devices, and methods related to the endovascular, percutaneous, or minimally invasive surgical treatment of bodily tissues, particularly for valve repair. The patent focuses on methods to detach previously sutured devices that hold leaflets of the mitral valve together, aiming to provide alternative and minimally invasive approaches to treat mitral valve regurgitation. The technology described in the patent could also be adapted for cutting tissue in other areas of the human anatomy through similar endovascular procedures. [Extracted from the article]

A patent has been issued for a catheter pump with a separable flared cannula and impeller. The patent, filed by inventors from Minnesota, describes a percutaneous heart pump that can be transitioned between a separated configuration and an operational configuration. The catheter pump includes an expandable cannula and an impeller system, with the impeller body movable relative to the cannula along a longitudinal axis. The invention aims to reduce the sheathing force of the pump and improve its delivery profile while maintaining a large operational profile. The patent was assigned to TC1 LLC. [Extracted from the article]

A patent has been issued to Edwards Lifesciences Corporation for native valve repair devices and procedures. The patent describes a valve repair system for repairing damaged heart valves, specifically the mitral valve. The system includes paddles, gripping members, and spacer elements that attach to the native valve of a patient. The invention aims to provide a less invasive alternative to open heart surgery for treating mitral valve regurgitation. The patent includes various configurations and methods for attaching the repair device to the native valve. [Extracted from the article]

A patent application by Atsens Co. Ltd. has been made available online for a bio-signal measuring device and method. The inventors highlight the importance of maintaining proper blood flow in the body and the risks associated with poor heart conditions. The patent application describes a portable electronic device that can receive and store bio-signal data from a measuring device, as well as transmit the data to an external device. The device aims to provide a noninvasive and cost-effective method for measuring electrocardiograms and diagnosing heart abnormalities. [Extracted from the article]

The US Patent and Trademark Office has published a patent application titled "Independent Gripper" by Abbott Cardiovascular Systems Inc. The application describes methods, devices, and systems for minimally invasive surgical treatment of bodily tissues, specifically tissue approximation or valve repair. The invention aims to provide improved methods for repairing cardiac valves without the need for open chest access or cardiopulmonary bypass. The patent application describes a fixation system with an implantable device and a delivery device, allowing for independent actuation of gripping elements to capture tissue. This system can be used in various anatomical regions and therapeutic procedures. [Extracted from the article]

A patent has been issued for a prosthetic heart valve developed by Cardiovalve Ltd. The valve is designed to address regurgitation caused by ischemic heart disease, which leads to the displacement of papillary muscles and dilation of the valve annulus. The implantable device consists of a tubular portion, an upstream support portion, and flanges. It can be delivered percutaneously and secured at the native valve by sandwiching tissue between the upstream support portion and the flanges. The patent provides detailed descriptions of the apparatus and its components. [Extracted from the article]

A patent has been issued for a biological chord repair system and methods by On-X Life Technologies Inc. The patent describes an adjustable artificial replacement chordae device/system for mitral valve repair surgery. The device allows for variable chordal lengths encountered during surgery and provides a more consistent and simple deployment of replacement chordae. The system includes needles, sutures, and a pledget, and the length of the artificial chordae can be adjusted by severing appropriate structures within the device. This patent offers a potential solution to the challenges faced by surgeons in attaching replacement chordae during mitral valve repair surgery. [Extracted from the article]

Terumo Kabushiki Kaisha, a medical device company based in Tokyo, Japan, has been issued a patent for a guide wire. The guide wire is designed to be inserted into a living body and includes an elongated shaft portion, a puncture portion, and a cover portion. The cover portion is elastically deformable and covers the puncture portion to prevent erroneous puncture and ensure safety. The guide wire has potential applications in cardiology and the treatment of arrhythmia. [Extracted from the article]

A patent has been issued to Innolife Co. Ltd. for the use of trientine, a copper chelating agent, to deliver copper to ischemic tissue. The patent describes how chronic myocardial ischemic conditions can lead to decreased capillary density and depressed angiogenesis, and how the loss of cardiac copper can block the activation of HIF-1a, a transcription factor involved in tissue repair and regeneration. The patent outlines methods for increasing intracellular copper levels, delivering copper into cells, inducing tissue repair, and promoting stem cell migration to ischemic tissue. The patent also includes specific claims for treating cardiac hypertrophy using a composition of trientine and a copper ion. [Extracted from the article]

Imbria Pharmaceuticals Inc. has been issued a patent for methods of treating heart failure with hibernating myocardium using modified forms of trimetazidine. Hibernating myocardium is a condition in which heart muscle tissue displays chronic contractile dysfunction, often caused by coronary artery disease. The current treatment for hibernating myocardium is revascularization, but this method has limitations and may not be suitable for all patients. The invention provides pharmacological therapies using modified forms of trimetazidine to improve cardiac efficiency and restore contractility in patients with hibernating myocardium. These methods can be used as an alternative or in combination with revascularization. [Extracted from the article]

A patent has been issued for a prosthetic heart valve developed by Cardiovalve Ltd. The valve is designed to address regurgitation caused by ischemic heart disease, which leads to the displacement and dilation of the papillary muscles and valve annulus. The implantable device features a valve body with a lumen, an upstream support portion, and legs for securing it to the native heart valve. The valve body is composed of struts arranged in a cellular structure, with double-strutted sides and rounded corners. The patent includes various claims related to the design and configuration of the prosthetic valve. [Extracted from the article]

Evalve Inc., a medical device company based in Santa Clara, California, has filed a patent application for a clip delivery catheter with a helical multi-lumen extrusion. The invention aims to improve the actuation of grippers used in mitral valve repair procedures. Mitral valve regurgitation, which can lead to heart failure, is often treated with open-heart surgery, but this new technique offers a less invasive alternative. The patent application provides detailed descriptions of the interventional tool and its method of actuating a medical device. [Extracted from the article]