1. Voiding and Storage Domain-Specific Symptom Score Outcomes After Prostate Artery Embolization for Lower Urinary Tract Symptoms and Urinary Retention
- Author
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T. Powell, Shivank Bhatia, Toby C. Chai, Bing Liu, Raj Ayyagari, and Lawrence H. Staib
- Subjects
medicine.medical_specialty ,business.industry ,Urinary retention ,Urology ,030232 urology & nephrology ,urologic and male genital diseases ,Single Center ,medicine.disease ,Prostatic artery embolization ,03 medical and health sciences ,0302 clinical medicine ,medicine.anatomical_structure ,Quality of life ,Prostate ,Lower urinary tract symptoms ,030220 oncology & carcinogenesis ,Artery embolization ,Medicine ,International Prostate Symptom Score ,medicine.symptom ,business - Abstract
Objective To characterize voiding and storage symptom domain-specific outcomes after prostate artery embolization (PAE) to treat lower urinary tract symptoms (LUTS) or urinary retention caused by benign prostatic hyperplasia (BPH). Methods Two hundred forty patients (age = 74.5 ± 8.6 years) underwent PAE between May 2013 and March 2020 at a single center for LUTS (n = 161) or urinary retention (n = 79). Total International Prostate Symptom Score (IPSS-t), voiding domain score (IPSS-v), storage domain score (IPSS-s), and Quality of Life score (QoL) were obtained pre-PAE for LUTS patients (IPSS-t = 21.7 ± 6.2, IPSS-v = 11.9 ± 4.3, IPSS-s = 9.6 ± 3.1, QoL = 4.5 ± 1.2), and post-PAE through 36 months (mean = 22.9 ± 15.2 months) for LUTS and retention patients. Mean relative changes in IPSS-t, IPSS-v, IPSS-s, and QoL were calculated for LUTS patients. Mean voiding or storage component scores were calculated for retention patients. Results For evaluable LUTS patients (n = 147), IPSS-t showed sustained substantial improvement through 36 months (6.3 ± 4.2-8.6 ± 7.6), as did QoL (1.1 ± 1.1-1.8 ± 1.5). One month after PAE, improvements in IPSS-v (69% ± 29%) were greater than in IPSS-s (46% ± 33%; P Conclusions PAE effectively treated BPH-related LUTS and retention. IPSS-v improved more than IPSS-s in LUTS patients, and remained lower in LUTS and retention patients through 36 months.
- Published
- 2021
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