1. Extubation Readiness in Preterm Infants: Evaluating the Role of Monitoring Intermittent Hypoxemia
- Author
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Elie G. Abu Jawdeh, M. Douglas Cunningham, Aayush Gabrani, Thomas M. Raffay, Philip M. Westgate, and Amrita Pant
- Subjects
Mechanical ventilation ,extubation ,Respiratory distress ,business.industry ,medicine.medical_treatment ,lcsh:RJ1-570 ,Gestational age ,lcsh:Pediatrics ,Article ,intubation ,Hypoxemia ,Anesthesia ,respiratory distress ,Pediatrics, Perinatology and Child Health ,Cohort ,medicine ,Intubation ,medicine.symptom ,intermittent hypoxemia ,business ,Prospective cohort study ,preterm ,Oxygen saturation (medicine) - Abstract
Preterm infants with respiratory distress may require mechanical ventilation which is associated with increased pulmonary morbidities. Prompt and successful extubation to noninvasive support is a pressing goal. In this communication, we show original data that increased recurring intermittent hypoxemia (IH, oxygen saturation <, 80%) may be associated with extubation failure at 72 h in a cohort of neonates <, 30 weeks gestational age. Current-generation bedside high-resolution pulse oximeters provide saturation profiles that may be of use in identifying extubation readiness and failure. A larger prospective study that utilizes intermittent hypoxemia as an adjunct predictor for extubation readiness is warranted.
- Published
- 2021
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