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Diabetic cardiomyopathy, characterized by left ventricular (LV) dysfunction and LV hypertrophy independent of myocardial ischaemia and hypertension, could contribute to the increased life-time risk of congestive heart failure seen in patients with diabetes. We assessed prospectively the prevalence, effectiveness of screening methods [brain natriuretic peptide (BNP) and C-reactive protein in combination with clinical parameters], and outcome of pre-clinical diabetic cardiomyopathy.We studied 100 adults (mean age 57.4 +/- 10.2 years, 44% females) with diabetes and no previous evidence of structural heart disease. By echocardiography, diabetic cardiomyopathy was present in 48% of patients. Screening with combinations of clinical parameters (gender, systolic blood pressure, and body mass index), but not BNP, resulted in high negative predictive values for diabetic cardiomyopathy. During a mean follow-up of 48.5 +/- 9.0 months, in the groups with and without diabetic cardiomyopathy, 12.5 vs. 3.9% (P0.2) patients died or experienced cardiovascular events and 37.5 vs. 9.6% (P0.002) had a deterioration in NYHA functional class. Overall event-free survival was 54 vs. 87% (P = 0.001) in the groups with and without diabetic cardiomyopathy, respectively. Brain natriuretic peptide was an independent predictor of events [odds ratio 3.5 (1.1-10.9), P = 0.02].Pre-clinical diabetic cardiomyopathy is common. Screening with combinations of simple clinical parameters, but not BNP, can be useful to identify those patients needing further evaluation. Patients with pre-clinical diabetic cardiomyopathy are at increased risk for functional deterioration and possibly cardiovascular events during follow-up. Brain natriuretic peptide was shown to be an independent predictor of future events.

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Introducción: La Escuela de Enfermería de la Universidad de São Paulo (EEUSP) se creó en 1942 y durante 17 años ofreció para sus estudiantes el sistema de internado. Este estudio tuvo como objetivos identificar el perfil socio-demográfico de alumnas orientales que estuvieran en esa Escuela, como internas, en el período 1953-1970, y analizar las hallazgos basados en la literatura sobre la historia de la enfermería. Material y método: Los datos fueron recogidos después del informe favorable del Comité de Investigación de la EEUSP, a través de un instrumento de recolección de datos, previamente preparado, para identificar el perfil socio-económico de los sujetos de investigación. Los datos fueron recogidos a través de los documentos de ingreso de las alumnas EEUSP, junto la Sección de Estudiantes de Grado de la misma institución. Resultados: Los resultados nos han permitido contextualizar los acontecimientos y aspectos sociales relevantes de la cultura oriental, revelando la articulación de estos aspectos con la elección profesional y la historia de estas mujeres. Discusiones: El proyecto pedagógico, la preparación teórica y práctica, los campos de prácticas y las facilidades ofrecidas por el sistema de internado posibilitan decir que la escuela atrajo el interés de muchas candidatas para el programa de enfermería en el momento. Este estudio ayudó a rescatar la historia de la EEUSP, desde la mirada de los documentos que retratan un poco la historia de estos antiguos alumnos, destacando el esfuerzo de esta institución para la formación de enfermeros para trabajar en diferentes escenarios de la práctica profesional. Introduction: The Nursing School of University de São Paulo SP (EEUSP) was established in 1942 and for 17 years it offered the internship for their students. This study aimed to identify the socio-demographic profile of eastern students formed who experienced the boarding system in the EEUSP, in that period of 1953 to 1970, and analyze the findings based on the literature on the history of nursing. Material and method: the data was collected after obtaining the successful evaluation of the Ethics in Research of the EEUSP, being used an instrument to collect data, previously developed, to identify the socio-economic status of subjects of investigation. Thus, data were obtained through the documents of entry of the former students at the Service of the Graduate of EEUSP. Results: The findings have enabled us to contextualize events and relevant social aspects of eastern culture, revealing the interface of these aspects with the professional choice and the story of these women. Discussions: The pedagogical project, the theoretical and practical preparation, the fields of training and the facilities of this system of the boarding school system possible to say that the school attracted the interest of many candidates for the nursing program at the time. This study helped to rescue the history of EEUSP, from the look of the documents that portrayed a little history of these former students, highlighting the effort of this institution for training nurses to work in different scenarios of professional practice. Introdução: A Escola de Enfermagem da Universidade de São Paulo (EEUSP) foi criada em 1942 e durante 17 anos ofereceu o internato para suas alunas. Este estudo teve como objetivos identificar o perfil sócio-demográfico de alunas que vivenciaram o internato na EEUSP, no período de 1953-1970, e analisar os achados com base na literatura sobre a história da enfermagem. Material e método: a coleta de dados ocorreu após a obtenção do parecer favorável do Comitê de Ética em Pesquisa da EEUSP, sendo utilizado um instrumento de coleta, previamente elaborado, para identificar o perfil sócio-econômico dos sujeitos da investigação. Assim, as informações foram obtidas por intermédio das fichas de ingresso das ex-alunas junto ao Serviço de Graduação da referida Escola. Resultados: Os achados possibilitaram-nos contextualizar fatos e aspectos sociais relevantes da cultura oriental, desvelando a interface desses aspectos com a escolha profissional e a história dessas mulheres. Discussões: O projeto pedagógico, a preparação teórico-prática, os campos de estágio e as facilidades do sistema de internato possibilitam afirmar que a Escola atraía o interesse de muitas candidatas ao curso de enfermagem na época. Este estudo contribuiu para resgatar a história da EEUSP, a partir do olhar sobre os documentos que retrataram um pouco a história dessas ex-alunas, destacandose o esforço dessa instituição para a formação de enfermeiras para atuarem em diferentes cenários las da prática profissional.