1. Reliability of single breath hold three-dimensional cine kat-ARC for the assessment of biventricular dimensions and function
- Author
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Silvia Pica, Marco Guglielmo, Andrea Baggiano, Paola Gripari, Andrea Annoni, Edoardo Conte, Saima Mushtaq, Mauro Pepi, Giuseppe Muscogiuri, Maria Elisabetta Mancini, Marco Gatti, Serena Dell'Aversana, Andrea Igoren Guaricci, Gianluca Pontone, Alberto Formenti, Mark G. Rabbat, Daniele Andreini, Muscogiuri, G, Gatti, M, Dell'Aversana, S, Pica, S, Andreini, D, Guaricci, A, Guglielmo, M, Baggiano, A, Mushtaq, S, Conte, E, Gripari, P, Annoni, A, Formenti, A, Mancini, M, Rabbat, M, Pepi, M, and Pontone, G
- Subjects
Male ,Intraclass correlation ,Imaging ,030218 nuclear medicine & medical imaging ,Breath Holding ,Computer-Assisted ,0302 clinical medicine ,Ventricular Dysfunction ,Medicine ,education.field_of_study ,Ejection fraction ,medicine.diagnostic_test ,General Medicine ,Middle Aged ,Cine ,030220 oncology & carcinogenesis ,cardiovascular system ,Female ,Cine sequence ,circulatory and respiratory physiology ,Adult ,Correlation coefficient ,Heart Ventricles ,Population ,Magnetic Resonance Imaging, Cine ,Cardiac imaging techniques ,Cine sequences ,Magnetic resonance imaging ,Three dimensional ,Ventricular function ,Aged ,Humans ,Image Interpretation, Computer-Assisted ,Imaging, Three-Dimensional ,Reproducibility of Results ,Subgroup analysis ,03 medical and health sciences ,Linear regression ,Radiology, Nuclear Medicine and imaging ,cardiovascular diseases ,education ,Image Interpretation ,Cardiac imaging technique ,Reproducibility ,business.industry ,Three-Dimensional ,business ,Nuclear medicine - Abstract
Purpose: To assess the accuracy and reproducibility of 3D-cine k-adaptative-t-autocalibrating reconstruction for cartesian sampling (3D cine kat-ARC) for quantification of biventricular volumes, ejection fraction and LV mass in clinical practice. Method: 74 patients underwent cardiac magnetic resonance for clinical indications. In the whole population 3D cine kat-ARC and 2D cine bSSFP images were acquired on short axis view. Subsequently, the population was divided in three subgroups (dilated, hypetrophic, other phenotypes). Two experienced observers performed analysis of volumes, biventricular function and left ventricular mass in the overall population and subgroups using an off-line workstation. Statistical analysis was performed using Student's t-test, linear regression and Bland-Altman plot, correlation coefficient η2 and the intraclass correlation coefficient (ICC). A cut-off value of p < 0.05 was considered statistically significant. Results: Biventricular volumes, function and left ventricular mass evaluated with 3D cine kat-ARC sequences did not show any significant difference compared to 2D bSSFP sequences in the overall population (p > 0.05). Bland-Altman analysis showed limited bias and narrow limits of the agreement for all measurements in overall population. Subgroup analysis showed a statistically significant difference (p = 0.04) for left ventricular ejection fraction (LVEF) in patients with a dilated phenotype; showing a minimum overestimation tendency for 3D cine kat ARC (2D cine bSSFP LVEF = 46.44 ± 15.83% vs 3D cine kat-ARC LVEF = 48.36 ± 16.50 %). Conclusions: 3D cine kat-ARC 3D sequences allow an accurate evaluation of biventricular volumes and function in a single breath hold.
- Published
- 2020