1. Assessment of anticoagulation treatments in non-valvular atrial fibrillation patients diagnosed in a basic health area
- Author
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Beatriz M. Aguilera Alcaraz, Julio Antonio Carbayo Herencia, José Alemán, José Abellán Huerta, Fernando Hernández Menárguez, and Consuelo Ariza Copado
- Subjects
Adult ,Male ,medicine.medical_specialty ,Vitamin K ,Cross-sectional study ,Non valvular atrial fibrillation ,Hemorrhage ,Medication Adherence ,Internal medicine ,Atrial Fibrillation ,Prevalence ,medicine ,Humans ,In patient ,International Normalized Ratio ,Medical prescription ,Aged ,General Environmental Science ,Aged, 80 and over ,business.industry ,General Engineering ,Anticoagulants ,Cardiac arrhythmia ,Atrial fibrillation ,Middle Aged ,medicine.disease ,Thrombosis ,Cross-Sectional Studies ,General Earth and Planetary Sciences ,Female ,Observational study ,business - Abstract
Atrial fibrillation (AF) is the most common cardiac arrhythmia. To assess the need for anticoagulation is essential for its management. Our objective was to investigate whether the indication of anticoagulation was adequate in patients diagnosed with non-valvular AF, given the CHA2-DS2-VASc scale, measuring the International Normalizad Ratio range (INR) in patients treated with anti-vitamin K drugs.This is an observational and cross sectional study. 232 patients with atrial fibrillation were included. We analyzed demographic, the CHA2-DS2-VASc and HAS-BLED variables, the treatment and INR values for 6 consequentive months. The confrontation of variables was performed using chi-square and Mantel-Haenzel test.The prevalence of AF was 1.05%. The 88.4% had CHA2-DS2-VASc ≥ 2. The 71.1% were taking anticoagulants, of which 58.2% were under antivitamin k. The 46.7% of patients taking antivitamin K, presented inadequate range of INR. There was a greater prescription of antivitamin k in patients with persistent or permanent AF compared to the paroxysmal form (62.8 vs. 37.2% p.001). The use of drugs that increase bleeding was associated with a worse control of INR after adjustment for the main variables of clinical relevance (odds ratio 2.17 [1.02-4.59], p=.043).The level of anticoagulation with antivitamin K was inadequate in our sample, despite a proper follow up and adherence to treatment. Patients with paroxysmal AF received less antivitamin K than those with persistent/permanent AF.
- Published
- 2018
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