1. Change in treatment modality and trends in survival among stage I non-small cell lung cancer patients: a population-based study
- Author
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Christian Finley, Hsien Yeang Seow, Noori Akhtar-Danesh, Gileh-Gol Akhtar-Danesh, and Saad Shakeel
- Subjects
Pulmonary and Respiratory Medicine ,Oncology ,medicine.medical_specialty ,education.field_of_study ,Stage I Non-Small Cell Lung Cancer ,business.industry ,medicine.medical_treatment ,Population ,non-small cell lung cancer (NSCLC) ,medicine.disease ,Population based study ,Radiation therapy ,03 medical and health sciences ,0302 clinical medicine ,Treatment modality ,030220 oncology & carcinogenesis ,Internal medicine ,medicine ,Original Article ,030212 general & internal medicine ,education ,business ,Survival rate ,Survival analysis - Abstract
BACKGROUND: A number of treatment modalities are available to patients with early non-small cell lung cancer (NSCLC) but there is inconsistency regarding their effects on survival. The associated survival of each treatment modality is crucial for patients in making informed treatment decisions. We aimed to examine the change in treatment modality and trends in survival for patients with stage I NSCLC and assess the association between treatment modality and survival. METHODS: All patients diagnosed with stage I NSCLC in the Canadian province of Ontario between 2007 and 2015 were included in this population-based study. We used a flexible parametric model to estimate the trends in survival rate. RESULTS: Overall, 11,910 patients were identified of which 7,478 patients (62.8%) received surgical resection and 2,652 (22.3%) radiation only. The proportion of patients who received radiation only increased from 13.2% in 2007 to 28.0% in 2015 (P-for-trend
- Published
- 2020