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PURPOSE This study examined the prevalence of major depression and generalized anxiety disorder (GAD) in pregnant women with and without a diagnosis of oligohydramnios. DESIGN AND METHODS The study sample included 53 pregnant women with a diagnosis of oligohydramnios and 80 healthy pregnant women subjects. Major depression and GAD were diagnosed with the Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition (SCID-I). FINDINGS Pregnant women with oligohydramnios had higher scores of depressive and anxiety symptom, and a higher prevalence rate of major depression (24.5% vs. 6.2%) and GAD (30.2% vs. 3.2%). PRACTICE IMPLICATIONS The results of the present study suggest that oligohydramnios appears to be associated with both major depression and GAD in pregnant women.

WOS:000450095400009, PubMed ID: 30042641, Introduction: This study presents the current prevalence of anxiety,mood, and personality disorders as well as factors associated with theexistence of psychiatric disorders in patients with benign paroxysmalpositional vertigo (BPPV).Methods: The study sample comprised 46 patients with BPPV and 74control subjects. Anxiety and mood disorders were ascertained via theStructured Clinical Interview for the Diagnostic and Statistical Manual(DSM) of Mental Disorders, Fourth Edition/Clinical Version. Personalitydisorders were diagnosed via the Structured Clinical Interview for DSM,Revised Third Edition, Personality Disorders.Results: Of the 46 patients, 18 (39.1%) had at least one mood or anxietydisorder and 13 (28.3%) had at least one personality disorder. The mostcommon Axis I and Axis II disorders in the patient group were majordepression in 8 (17.4%) and obsessive–compulsive personality disorderin 10 (21.7%) patients, respectively. It was found that major depression(p0.021), generalized anxiety disorder (p0.026) and obsessive–compulsive personality disorder (p0.001) were more prevalent in theBPPV group compared with the control group.Conclusion: Results suggest that psychiatric disturbances should becarefully checked in patients with BPPV due to the relatively high rateof comorbidity., Amaç: Bu çalışma benign paroksismal pozisyonel vertigo (BPPV)hastalarında psikiyatrik bozuklukların varlığı ile ilişkili faktörlerin ve anksiyete, duygudurum ve kişilik bozukluklarının mevcut yaygınlığını sunmaktadır. Yöntem: Araştırma örneklemi 46 BPPV hastası ve 74 kontrol olgusundan oluşmuştur. Anksiyete ve duygudurum bozuklukları Structured Clinical Interview for the Diagnostic and Statistical Manual of Mental Disorders, Fourth Edition/Clinical Version yoluyla tespit edildi. Kişilik bozuklukları tanısı Structured Clinical Interview for DSM, Revised Third Edition Personality Disorders ile konuldu. Bulgular: Kırk altı hastanın 18’in (%39,1) de en az bir duygudurum yada anksiyete bozukluğu ve 13’ün (%28,3) de en az bir kişilik bozukluğu vardı. Eksen I ve Eksen II tanıları olarak en sık, sırasıyla 8 (%17,4) hastada majör depresyon ve 10 (%21,7) hastada obsesif kompulsif kişilik bozukluğu vardı. Major depresyon (p:0,021), yaygın anksiyete bozukluğu (p:0,026) ve obsesif kompulsif kişilik bozukluğu (p:0,001) yaygınlığının kontrol grubu ile karşılaştırıldığında BPPV grubunda daha sık görüldüğü bulunmuştur. Sonuç: Sonuçlar; BPPV tanılı hastaların, psikiyatrik bozuklukların yüksek oranlı komorbiditeleri nedeniyle dikkatle değerlendirilmeleri gerektiğini ortaya koymaktadır.

The melatonin as the pineal gland's secretory product is implicated in the pathophysiology of migraine. Melatonin has critical functions in human physiology, and research underscores the importance of melatonin in circadian rhythm, sleep, and mood regulation. Clinical observations have indicated that migraine attacks have a seasonal, menstrual, and circadian timing, suggesting that chronobiological mechanisms and their alterations may causally involve in the etiology of the disease. However, the topic has received relatively little attention in the migraine literature. Associations between melatonin, circadian preference, sleep, and mood states were investigated in the current study. Fifty-five patients (47 females and 8 males) were compared to 57 gender and age-matched control subjects (40 females and 17 males). A socio-demographical questionnaire, the Beck Depression Inventory, Beck Anxiety Inventory (BAI), Pittsburgh Sleep Quality Index (PSQI), Profile of Mood States (POMS), and Morningness-Eveningness Questionnaire were administered to volunteers. Blood samples were taken from all participants at about 1:00 AM in an unlit room not to hamper melatonin secretion, and blood melatonin levels were measured using quantitative ELISA test. In comparison with controls, melatonin levels were significantly lower among migraine patients. Migraineurs reported significantly greater scores on the BAI, confusion-bewilderment subscale of the POMS, and total and sleep latency subscale of the PSQI. Migraine patients who had nausea during the migraine attacks and who reported bouts relevant to certain food consumption, such as cheese or chocolate, had significantly lower levels of melatonin. Contrarily, groups did not reveal statistically substantial difference in circadian preferences.