1. En-face analysis of short posterior ciliary arteries crossing the sclera to choroid using wide-field swept-source optical coherence tomography
- Author
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Raphael Atia, Raphael Lejoyeux, Jay Chhablani, Kunal K. Dansingani, Kiran Kumar Vupparaboina, José-Alain Sahel, Mohammed Nasar Ibrahim, S. Suthaharan, Fondation Ophtalmologique Adolphe de Rothschild [Paris], Centre Hospitalier National d'Ophtalmologie des Quinze-Vingts (CHNO), University of Pittsburgh School of Medicine, Pennsylvania Commonwealth System of Higher Education (PCSHE), Indian Institute of Technology [Hyderabad] (IIT Hyderabad), University of North Carolina [Greensboro] (UNCG), University of North Carolina System (UNC), and University of Pittsburgh (PITT)
- Subjects
Male ,medicine.medical_specialty ,genetic structures ,Science ,[SDV]Life Sciences [q-bio] ,Posterior pole ,Visual Acuity ,Article ,Ciliary Arteries ,03 medical and health sciences ,0302 clinical medicine ,Medical research ,Optical coherence tomography ,medicine.artery ,Ophthalmology ,medicine ,Humans ,Segmentation ,Retrospective Studies ,Multidisciplinary ,medicine.diagnostic_test ,business.industry ,Choroid ,Healthy subjects ,Short posterior ciliary arteries ,Wide field ,eye diseases ,Sclera ,medicine.anatomical_structure ,Cross-Sectional Studies ,Optics and photonics ,030221 ophthalmology & optometry ,Medicine ,Female ,sense organs ,Anatomy ,business ,030217 neurology & neurosurgery ,Algorithms ,Tomography, Optical Coherence - Abstract
To study the topographic distribution of the short posterior ciliary arteries (SPCA) entry sites into the choroid in normal eyes using structural en-face swept source optical coherence tomography (SS-OCT). Retrospective analysis of SS-OCT scans (wide-field structural SS-OCT 12 × 12 mm) of 13 healthy subjects was performed. Cross-sectional swept-source OCT scans derived from a volume scan were represented as en-face image display following the Choroid-Scleral Interface to obtain en-face OCT. SPCAs in their last scleral location before choroidal entrance were identified manually, counted and localized by two masked observers. Correlations between two masked observers were analyzed using inter- and intra-class correlation. Accuracy for the choroidal inner and outer border segmentation was 95–99%. Eighteen eyes from 13 normal subjects were included for SPCA analysis. The mean number of arteries was 13.8 ± 3.5 per eye. Thirty-six percent were in the center of the posterior pole image; however, 21% were in the temporal part of the posterior pole. Median accuracy of the detection is 0.94. The correlation between the two observers was fair (0.54). Our algorithm allows visualization of the SPCA at the posterior pole of the eye using wide-field en-face SS-OCT. It can also help the clinicians to study the SPCAs in numerous ocular diseases, particularly its relationship with focal choroidal diseases.
- Published
- 2021