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Introduction: Published data regarding the association between solute carrier family 30, member 8 (SLC30A8) rs13266634 polymorphism and type 2 diabetes mellitus (T2DM) and impaired glucose regulation (IGR) risks in Chinese population are in-consistent. The purpose of this meta-analysis was to evaluate the association between SLC30A8 rs13266634 and T2DM/IGR in a Chinese population. Material and Methods: Three English (PubMed, Embase, and Web of Science) and three Chinese databases (Wanfang, CNKI, and CBMD database) were used for searching articles from January 2005 to January 2018. Odds ratio (OR) and 95% confidence interval (95%CI) were calculated with the random-effect model. Trial sequential analysis was also utilized. Results: Twenty-eight case-control studies with 25,912 cases and 26,975 controls were included for SLC30A8 and T2DM. Pooled risk allele C frequency for rs13266634 was 60.6% (95%CI: 59.2-62.0%) in the T2DM group and 54.8% (95%CI: 53.2-56.4%) in the control group which had estimated OR of 1.23 (95%CI: 1.17-1.28). Individuals who carried major homozygous CC and heterozygous CT genotype were at 1.51 and 1.23 times higher risk of T2DM, respectively, than those carrying minor homozygous TT. The most appropriate genetic analysis model was the co-dominant model based on comparison of OR1, OR2 and OR3. Five articles that involved 4,627 cases and 6,166 controls were included for SLC30A8 and IGR. However, no association was found between SLC30A8 rs13266634 and IGR (C vs. T, OR = 1.13, 95%CI: 0.98-1.30, p = 0.082). TSA revealed that the pooled sample sizes of T2DM exceeded the estimated required information size but not the IGR. Conclusion: The present meta-analysis demonstrated that SLC30A8 rs13266634 was a potential risk factor for T2DM, and more studies should be performed to confirm the association between rs13266634 polymorphism and IGR.

The cadmium silicate glass samples of 40SiO 2 -14Al 2 O 3 -(40-x) CdO-2Li 2 O-2K 2 O-2Na 2 O-xEr 2 O 3 (x=0.15, 0.20, 0.25, 0.30, 0.35, 0.40 mol) was prepared by high-temperature solid-state reaction method, and it is pumped at 488 nm, 532 nm and 800 nm respectively. The results indicate that the main peak wavelengths are at 547 nm, 731 nm and 1534 nm excited at 488 nm. The relationship of the intensity between the emission light of 731 nm and Er3 + -doped concentration is nonlinear. Near-infrared light nearby 1534 nm is excited at 532 nm and 800 nm, but it is weaker at 800 nm. The glass samples open a outlook of application for conversion luminescence materials.

The glass samples of SiO 2 -Al 2 O 3 -CdO-Li 2 O-K 2 O-Na 2 O with different Nd 3+ -doped concentration are prepared by high-temperature solid-state reaction method, and test the absorption spectrums as well as emission spectrum excited at 488 nm, 532 nm and 808 nm. The third-order optical nonlinear properties of glasses samples are investigated by the z-scan technique. With the increment of doping concentration of Nd 3+ , the third-order nonlinear refractive index and the absorption index increase, so it belongs to the self-focusing and reverse saturated absorption medium. The glass samples open a outlook of application for nonlinear optical medium and excellent luminescence materials.