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No cochlear otosclerosis in infants with congenital bilateral SNHL has been reported.We report an infant male with bilateral cochlear otosclerosis, suggesting that cochlear otosclerosis may be a congenital disease and to further analyze the etiology of and genetic expression in congenital bilateral cochlear otosclerosis. We also describe the clinical characteristics and experience of patients with bilateral cochlear otosclerosis treated with cochlear implants (CIs).Seven patients, including an infant, who were diagnosed with cochlear otosclerosis underwent CI surgery. Their medical records, audiological and radiological results, surgical procedures, and CI outcomes were collected and reviewed.The median age at hearing loss was 38 years, ranging from 0 to 47 years. The child had bilateral hearing loss at birth and received a CI at 1 year of age. He also had growth retardation and was diagnosed with 3q+/3p- syndrome. All patients (8 ears) had better postoperative auditory performance than that preoperatively.Although cochlear otosclerosis often starts at middle age and progresses slowly, it may be a congenital disease that is related to chromosome abnormality. This disease presents with SNHL or MHL, and treatment with a CI is beneficial.

Depression is the most common psychiatric disorder in the general population. An effective treatment of depression requires early detection. In reschedule this paper, a novel algorithm is presented based on eye-tracking and a self-rating high-risk depression screening scale (S-hr-DS) for early depression screening. In this algorithm, a subject scan path is encoded by semantic areas of interest (AOIs). AOIs are dynamically generated by the POS (part-of-speech) tagging of Chinese words in the S-hr-DS items. The proposed method considers both temporal and spatial information of the eye-tracking data and encodes the subject scan path with semantic features of items. The support vector machine recursive feature elimination (SVM-RFE) algorithm is employed for feature selection and model training. Experimental results on a data set including 69 subjects show that our proposed algorithm can achieve an accuracy of 81% with 76% in sensitivity and 79% in F1-score, demonstrating a potential application in high-risk depression detection.

Cochlear implantation is safe for simple case presentations. However, facial nerve (FN) aberrations may impede insertion of the electrode through a round window and increase the risk of iatrogenic FN injury. We developed a novel method of cochlear implantation, a present the case of a child with FN aberrations. Inferior displacement of a horizontal segment of FN lay on the surface of th e promontory, obscuring the round window. The oval window was used and the electrode successfully inserted. No postoperative complications occurred, and significant improvement in speech perception was achieved. This novel approach is suitable for patients with FN aberrations.