1. Clinical use of steroids in viral central nervous system (CNS) infections: three challenging cases
- Author
-
Vivian S. Namale, Kiran T. Thakur, Kathryn Rimmer, Carla Y. Kim, Adam Kroopnick, Ugoada Ofoezie, and Dan Tong Jia
- Subjects
medicine.medical_specialty ,Neurology ,biology ,business.industry ,Cns infections ,viruses ,Central nervous system ,Viral CNS Infections ,Varicella zoster virus ,virus diseases ,biology.organism_classification ,medicine.disease_cause ,Cellular and Molecular Neuroscience ,medicine.anatomical_structure ,Steroid use ,Virology ,Immunology ,Medicine ,Neurology (clinical) ,Powassan virus ,Cns disease ,business - Abstract
The role of adjunctive corticosteroids in reducing morbidity and mortality of viral CNS infections remains poorly defined. Clinicians are often left in a quagmire regarding steroid use in complex and rapidly evolving viral CNS infections. Limited studies have explored the underlying mechanisms behind the potential benefit of steroids. Here, we describe steroid use in three cases of viral CNS disease: varicella zoster virus (VZV), Powassan virus, and influenza A-associated acute necrotizing encephalopathy.
- Published
- 2021