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In many industry applications, the self-locking and interlocking switches are usually used to control electrical equipment or applied to automation control. The electronic self-locking /interlocking switches can improve the disadvantages of the conventional self-locking/interlocking switches using relay types; however, they can not achieve the real interlocking state when two push buttons are pressed at the same time. In this paper, a fully self-locking/interlocking electronic switch circuit based on MOSFET is proposed to solve the above problem by using a technology of signal mutual control.

Alzheimer's disease (AD), one of the progressive neurodegenerative disorders, is characterized by clinical features such as memory loss, acquired skill loss, apraxia, and interpersonal and social communication disorders. The AD hallmarks at the neuropathological level include intracellular neurofibrillary tangles constituted by the hyperphosphorylated tau protein as well as the senile extracellular plaques dominated by the amyloid-β (Aβ) deposits. At present, AD treatment that mainly targeted towards improving symptoms and effective drugs to delay or stop disease progression is lacking. Vaccines and antibody-based therapies are a type of natural, synthetic, and gene recombinant biological product that treat or prevent disease progression by stimulating specific or non-specific immune responses. Compared with traditional targeted drugs, vaccines and antibodybased therapies have better safety and effectiveness and can even maintain the expression and stability of Aβ and Tau proteins in patients for a long time. Logically, vaccines and antibody-based therapies are somewhat different from traditional drugs because these drugs can achieve the therapeutic effect of AD by activating immune cells and regulating the immune system of patients themselves, thereby clearing disease-related proteins and long-term survival. Complete cure is also observed in some patients after receiving the immunotherapy. Currently available vaccines and antibody-based therapies mainly target Aβ and phosphorylated tau proteins. There are 44 vaccines and antibodybased therapies for AD, among which nine drugs are discontinued, three drugs are inactive, eleven drugs are in clinical phase 1, twelve drugs are in clinical phase 2, and seven drugs are in clinical phase 3. Currently, no vaccines and antibody-based therapies have been approved for AD treatment. In this paper, we review and analyse the research progress of vaccines and antibody-based therapies that are used to treat AD.

Since the applications of mobile WiFi and Bluetooth signals are very popular and mature, in this paper, we propose an intelligent parking management system based on the technologies of WiFi positioning and Bluetooth control to manage the vehicles entering or exiting the parking lot. Only a dedicated app for the parking lot needs to be installed on the user's mobile phone, when the user drives near the parking lot, the roadside unit (RSU) end of parking lot can automatically complete the operation of vehicle identification. Based on the convenience and practicability, therefore, such a parking system using WiFi positioning and Bluetooth control is worth popularizing.

In this paper, a co-designed compact filtering monopole antenna based on the recently developed two-stage split ring resonator (SRR)-inspired high-frequency-selective filter is proposed and demonstrated. The used filter is consisting of two groups of twist-modified SRRs and is inserted in the feeding line of a conventional wide band planar monopole antenna to filter out the unwanted out-of-band antenna gain. The impedance matching and radiation gain of the co-designed filtering antenna are numerically and experimentally demonstrated and a good agreement between them is obtained. The measured results show that such filtering antenna has a 3-dB gain bandwidth of 16.7% centered at 2.4 GHz with peak gain of 2.4 dBi and sharp dropped out-of-band radiation gain feature.

This Letter proposes a circularly polarised (CP) monopole antenna with filtering function, which is achieved by integrating a miniaturised coupled filter based on the bent-loop resonators. The circular-polarisation is obtained by using the falcate-shaped patch as the radiation part, and the existence of the coupled filter in the feeding line would not affect the CP radiation performances. Both numerical simulation and experimental demonstration are performed for the designed CP filtering antenna, and good agreements are obtained. The designed antenna with dimension of 70 × 75 mm2 exhibits good frequency selective performances for the return loss, gain and axial ratio at 2.45 GHz with measured impedance matching bandwidth (|S 11| < 10 dB) of 0.23 GHz. Such CP filtering antenna is a good candidate for the emerging application area, e.g. wearable biotelemetric devices.

Research on the Internet of Things (IoT) has been a hot spot in recent years. Resource authentication and management in IoT is a most important and challenging problem and is far to be solved. In this paper, we propose an effective distributed hierarchical IoT resource authentication and management model based on the key technologies of distributed hash table, Chord Ring and public key infrastructure. By using the exceptional advantage of search and Research on the Internet of Things (IoT) has been a hot spot in recent years. Resource authentication and management in IoT is a most important and challenging problem and is far to be solved. In this paper, we propose an effective distributed hierarchical IoT resource authentication and management model based on the key technologies of distributed hash table, Chord Ring and public key infrastructure. By using the exceptional advantage of search and query ability of the above technologies, the proposed model owns enhanced security and improved efficiency. Simulation results show that the proposed model can mutually authenticate the IoT end entities each other in more short time compared to other existing approaches. query ability of the above technologies, the proposed model owns enhanced security and improved efficiency. Simulation results show that the proposed model can mutually authenticate the IoT end entities each other in more short time compared to other existing approaches.