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miR21-mediated activation of TLR8 controls neuropathic pain., TLRs have been well characterized in the context of immunity, although TLR8 is understudied due to its controversial function in mice. In this issue of JEM, the new work by Zhang et al. (https://doi.org/10.1084/jem.20180800) demonstrates that TLR8 activated by miR-21 controls neuropathic pain using a non-MyD88–dependent pathway.

A miniaturized varactor-tuned microstrip bandpass filter (BPF) based on an improved ring resonator is presented in this paper. The proposed BPF is comprised of a ring as 1/2 λ resonator with two varactors in the middle section and a coupling scheme. The variation of coupling coefficient can be controlled by using a capacitor. The center frequency of the lower passband can be tuned from 3.2 to 3.9 GHz, while the center frequency of the upper passband is at 4.9 GHz and it is fixed during the process. Theoretical analysis and design approach are demonstrated. Finally, the predicted results are compared with measured data and good agreement is reported.

In this paper, a compact tunable dual-stop-band fllter is proposed. The proposed fllter is based on the combination of double H-shaped defected ground structure (HDGS) and E-shaped defected microstrip structure (EDMS). The loaded HDGS/EDMS varactor diode is introduced to realize the tunable dual-stop-band fllter. The equivalent-circuit models and theoretical analysis of the proposed structure are presented; also its performance evaluation is compared with traditional structure. The proposed fllter has the characteristic of two independently adjustable stopbands and wide tuning range. EDMS also shows size reduction up to 38% compared with the T- shaped defected microstrip structure. The measured performance of the tunable dual-stop-band fllter agrees well with the simulation results.

A novel compact microstrip-fed planar monopole antenna with quad-notched bands is presented. The proposed antenna is based on one rectangular-stepped-patch. To achieve the higher resonance over the 12GHz, one lateral L-shaped structure is embedded in the ground. By inserting four U-shaped slots in the radiation patch, quad band-notched properties in the WiMAX (3.3{3.6GHz), INSAT (4.5{4.8GHz), lower WLAN (5.15{5.35GHz) and higher WLAN (5.725{5.825GHz) are obtained. Experimental results indicate that the designed UWB antenna can obtain broadband matched impedance values, good frequency selectivity over the notched bands, relatively ∞at group delay and nearly omni-directional transmission characteristics across the UWB frequencies. More importantly, the quad-notched bands can be reconflgurable by shorting the corresponding U-shaped slots.