1. Usefulness of narrow band imaging with magnifying endoscopy for the differential diagnosis of cancerous and noncancerous laryngeal lesions.
- Author
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Hosono, Hiroshi, Katada, Chikatoshi, Okamoto, Tabito, Ichinoe, Masaaki, Sakamoto, Yasutoshi, Matsuba, Hiroki, Kano, Koichi, Ishido, Kenji, Tanabe, Satoshi, Koizumi, Wasaburo, and Yamashita, Taku
- Subjects
DIFFERENTIAL diagnosis ,LARYNGEAL cancer ,CANCER diagnosis ,VOCAL cords ,ODDS ratio ,MULTIVARIATE analysis - Abstract
Background: We evaluated the accuracy of endoscopic findings observed by narrow band imaging (NBI) combined with magnifying gastrointestinal endoscopy (GIE) for the differential diagnosis of cancerous and noncancerous laryngeal lesions. Methods: A total of 166 vocal cord lesions for which good images were obtained on NBI with magnifying GIE were evaluated with respect to the following 6 variables: macroscopic type, tumor location, color, white coat, keratinization, and abnormal microvessels. Results: Multivariate analysis showed that white coat (odds ratio [OR], 2.95, P = 0.05), keratosis (OR, 3.14, P = 0.02) and abnormal microvessels (OR, 31.1, P < 0.0001) were significantly related to laryngeal cancer. In the diagnosis of laryngeal cancer, the sensitivity, specificity, positive predictive value, negative predictive value, and diagnostic accuracy of abnormal microvessels were 84.4%, 88.6%, 91%, 80.5%, and 86.1%, respectively. Conclusion: The abnormal microvessels on NBI combined with magnifying GIE are useful for the differential diagnosis of laryngeal lesions. [ABSTRACT FROM AUTHOR]
- Published
- 2019
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