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Your search keyword '"Takahashi, Yoshiyuki"' showing total 1 results
Start Over Author "Takahashi, Yoshiyuki" Topic cancer genes Topic genetic mutation
1 results on '"Takahashi, Yoshiyuki"'

1. Mutation analysis of SIPA1 in patients with juvenile myelomonocytic leukemia.

Author

Yoshida, Nao, Yagasaki, Hiroshi, Takahashi, Yoshiyuki, Kudo, Kazuko, Manabe, Atsushi, and Kojima, Seiji

Subjects
LEUKEMIA in children, GENETIC mutation, CANCER genes, GRANULOCYTE-macrophage colony-stimulating factor, CANCER research
Abstract

The article discusses the pathological mutation of the human gene SIPA1 in patients with juvenile myelomonocytic leukemia (JMML). Although the malignancy is typically associated with constructive activation of the granulocyte-macrophage colony-stimulating factor (GM-CSF) receptor/Ras/Raf/MEK/ERK signaling, the researchers claim that its correlation with the SIPA1 gene is unlikely.

Published
2008
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