1. Phase Transfer Catalyzed Enantioselective Strecker Reactions of alpha-Amido Sulfones with Cyanoydrins
- Author
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Raquel P. Herrera, Luca Bernardi, Alfredo Ricci, Valentina Sgarzani, Daniel Pettersen, Francesco Fini, R.P.Herrera, V. Sgarzani, L. Bernardi, F. Fini, D. Pettersen, and A. Ricci
- Subjects
inorganic chemicals ,Reaction mechanism ,Strecker amino acid synthesis ,Carbonates ,Stereoisomerism ,Catalysis ,Phase Transition ,chemistry.chemical_compound ,Phase (matter) ,Nitriles ,Acetone ,Organic chemistry ,Sulfones ,Cyanohydrin ,ORGANOCATALISI ASIMMETRICA ,Acetone cyanohydrin ,Molecular Structure ,Chemistry ,CIANIDRINE ,organic chemicals ,Organic Chemistry ,Enantioselective synthesis ,Water ,General Medicine ,Potassium ,REAZIONE DI STRECKER - Abstract
A study into the use of a chiral phase-transfer catalyst in conjunction with acetone cyanohydrin to effect the enantioselective formation of alpha-amino nitriles from alpha-amido sulfones is described. This novel catalytic asymmetric Strecker reaction is analyzed with regard to the possible mechanistic basis.
- Published
- 2006