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7 results on '"Schwerzmann, Markus"'

2. [2020 ESC guidelines on treatment of adult congenital heart disease (ACHD)].

Author

Ruperti-Repilado FJ, Thomet C, and Schwerzmann M

Subjects
Adult, Humans, Morbidity, Registries, Retrospective Studies, Cardiology, Heart Defects, Congenital diagnosis, Heart Defects, Congenital therapy
Abstract

The new guidelines of the European Society of Cardiology (ESC) on treatment of adult congenital heart disease (ACHD) were published in August 2020. The previous recommendations from 2010 were adapted to reflect the diagnostic and therapeutic progress made in the past 10 years. The recommendations are nearly exclusively based on an evidence level C (consensus of opinion of experts or knowledge from small studies, retrospective studies or registries). This is not surprising considering the heterogeneous patient population with a multitude of cardiac defects and repair strategies performed in the past. The cohort of ACHD patients is steadily growing in numbers and is becoming older due to reduced perioperative morbidity and mortality and further medical progress. Therefore, the current guidelines do not focus solely on the acute treatment of cardiac problems but also address the importance of a comprehensive longitudinal follow-up for a chronic, lifelong disorder. On a defect-specific level, progress in the past decade in arrhythmia diagnosis and management, percutaneous interventions and the treatment of pulmonary arterial hypertension have led to many revised or new recommendations. Finally, the 2020 guidelines also address for the first time the management of coronary anomalies.

Published
2021
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4. 2017 ESC focused update on dual antiplatelet therapy in coronary artery disease developed in collaboration with EACTS

Author

Valgimigli, Marco, Bueno, Héctor, Byrne, Robert A, Collet, Jean-Philippe, Costa, Francesco, Jeppsson, Anders, Jüni, Peter, Kastrati, Adnan, Kolh, Philippe, Mauri, Laura, Montalescot, Gilles, Neumann, Franz-Josef, Petricevic, Mate, Roffi, Marco, Steg, Philippe Gabriel, Windecker, Stephan, Zamorano, Jose Luis, Levine, Glenn N, Badimon, Lina, Vranckx, Pascal, Agewall, Stefan, Andreotti, Felicita, Antman, Elliott, Barbato, Emanuele, Bassand, Jean-Pierre, Bugiardini, Raffaele, Cikirikcioglu, Mustafa, Cuisset, Thomas, De Bonis, Michele, Delgado, Victora, Fitzsimons, Donna, Gaemperli, Oliver, Galiè, Nazzareno, Gilard, Martine, Hamm, Christian W, Ibanez, Borja, Iung, Bernard, James, Stefan, Knuuti, Juhani, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lip, Gregory, Piepoli, Massimo Francesco, Pierard, Luc, Schwerzmann, Markus, Sechtem, Udo, Simpson, Iain A, Uva, Miguel Sousa, Stabile, Eugenio, Storey, Robert F, Tendera, Michal, Van de Werf, Frans, Verheugt, Freek, Aboyans, Victor, Coca, Antonio, Collet, Jean- Philippe, Coman, Ioan Mircea, Dean, Veronica, Delgado, Victoria, Hindricks, Gerhard, Katus, Hugo A, Lancellotti, Patrizio, McDonagh, Theresa, Ponikowski, Piotr, Richter, Dimitrios J, Shlyakhto, Evgeny, Roithinger, Franz Xaver, Aliyev, Farid, Stelmashok, Valeriy, Desmet, Walter, Postadzhiyan, Arman, Georghiou, Georgios P, Motovska, Zuzana, Grove, Erik Lerkevang, Marandi, Toomas, Kiviniemi, Tuomas, Kedev, Sasko, Massberg, Steffen, Alexopoulos, Dimitrios, Kiss, Robert Gabor, Gudmundsdottir, Ingibjorg Jona, McFadden, Eugène P, Lev, Eli, De Luca, Leonardo, Sugraliyev, Akhmetzhan, Haliti, Edmond, Mirrakhimov, Erkin, Latkovskis, Gustavs, Petrauskiene, Birute, Huijnen, Steve, Magri, Caroline Jane, Cherradi, Rhizlan, Ten Berg, Jurrien M, Eritsland, Jan, Budaj, Andrzej, Aguiar, Carlos Tavares, Duplyakov, Dmitry, Zavatta, Marco, Antonijevic, Nebojsa M, Fras, Zlatko, Montoliu, Antonio Tello, Varenhorst, Christoph, Tsakiris, Dimitri, Addad, Faouzi, Aydogdu, Sinan, Parkhomenko, Alexander, Kinnaird, Tim, ESC Scientific Document Group, ESC Committee for Practice Guidelines (CPG), ESC National Cardiac Societies, Valgimigli, Marco, Bueno, Héctor, Byrne, Robert A., Collet, Jean-Philippe, Costa, Francesco, Jeppsson, Ander, Kastrati, Adnan, Kolh, Philippe, Mauri, Laura, Montalescot, Gille, Neumann, Franz-Josef, Petricevic, Mate, Roffi, Marco, Steg, Philippe Gabriel, Zamorano, Jose Lui, Levine, Glenn N., Badimon, Lina, Vranckx, Pascal, Agewall, Stefan, Andreotti, Felicita, Antman, Elliott, Barbato, Emanuele, Bassand, Jean-Pierre, Bugiardini, Raffaele, Cikirikcioglu, Mustafa, Cuisset, Thoma, De Bonis, Michele, Delgado, Victora, Fitzsimons, Donna, Galiè, Nazzareno, Gilard, Martine, Hamm, Christian W., Ibanez, Borja, James, Stefan, Knuuti, Juhani, Landmesser, Ulf, Leclercq, Christophe, Lettino, Maddalena, Lip, Gregory, Piepoli, Massimo Francesco, Pierard, Luc, Schwerzmann, Marku, Sechtem, Udo, Simpson, Iain A., Uva, Miguel Sousa, Stabile, Eugenio, Storey, Robert F., Tendera, Michal, Van De Werf, Fran, Verheugt, Freek, Aboyans, Victor, Windecker, Stephan, Coca, Antonio, Coman, Ioan Mircea, Dean, Veronica, Delgado, Victoria, Gaemperli, Oliver, Hindricks, Gerhard, Iung, Bernard, Jüni, Peter, Katus, Hugo A., Lancellotti, Patrizio, McDonagh, Theresa, Ponikowski, Piotr, Richter, DImitrios J., Shlyakhto, Evgeny, Roithinger, Franz Xaver, Aliyev, Farid, Stelmashok, Valeriy, Desmet, Walter, Postadzhiyan, Arman, Georghiou, Georgios P., Motovska, Zuzana, Grove, Erik Lerkevang, Marandi, Tooma, Kiviniemi, Tuoma, Kedev, Sasko, Massberg, Steffen, Alexopoulos, DImitrio, Kiss, Robert Gabor, Gudmundsdottir, Ingibjorg Jona, McFadden, Eugène P., Lev, Eli, De Luca, Leonardo, Sugraliyev, Akhmetzhan, Haliti, Edmond, Mirrakhimov, Erkin, Latkovskis, Gustav, Petrauskiene, Birute, Huijnen, Steve, Magri, Caroline Jane, Cherradi, Rhizlan, Ten Berg, Jurrien M., Eritsland, Jan, Budaj, Andrzej, Aguiar, Carlos Tavare, Duplyakov, Dmitry, Zavatta, Marco, Antonijevic, Nebojsa M., Fras, Zlatko, Montoliu, Antonio Tello, Varenhorst, Christoph, Tsakiris, DImitri, Addad, Faouzi, Aydogdu, Sinan, Parkhomenko, Alexander, Kinnaird, Tim, Valgimigli, M, Bueno, H, Byrne, Ra, Collet, Jp, Costa, F, Jeppsson, A, Juni, P, Kastrati, A, Kolh, P, Mauri, L, Montalescot, G, Neumann, Fj, Petricevic, M, Roffi, M, Steg, Pg, Windecker, S, Zamorano, Jl, Levine, Gn, Badimon, L, Vranckx, P, Agewall, S, Andreotti, F, Antman, E, Barbato, E, Bassand, Jp, Bugiardini, R, Cikirikcioglu, M, Cuisset, T, De Bonis, M, Delgado, V, Fitzsimons, D, Oliver, G, Galie, N, Gilard, M, Hamm, Cw, Ibanez, B, Iung, B, James, S, Knuuti, J, Landmesser, U, Leclercq, C, Lettino, M, Lip, G, Piepoli, Mf, Pierard, L, Schwerzmann, M, Sechtem, U, Simpson, Ia, Uva, M, Stabile, E, Storey, Rf, Tendera, M, Van De Werf, F, Verheugt, F, Aboyans, V, Byrne, Robert A, Levine, Glenn N, Badimon L, Vranckx P, Agewall S, Andreotti F, Antman E, Barbato E, Bassand JP, Bugiardini R, Cikirikcioglu M, Cuisset T, De Bonis M, Delgado V, Fitzsimons D, Gaemperli O, Galiè N, Gilard M, Hamm CW, Ibanez B, Iung B, James S, Knuuti J, Landmesser U, Leclercq C, Lettino M, Lip G, Piepoli MF, Pierard L, Schwerzmann M, Sechtem U, Simpson IA, Uva MS, Stabile E, Storey RF, Tendera M, Van de Werf F, Verheugt F, Aboyans V, Alma Mater Studiorum Universita' di Bologna, DIPARTIMENTO DI MEDICINA SPECIALISTICA, DIAGNOSTICA E SPERIMENTALE, DIPARTIMENTO DI SCIENZE MEDICHE E CHIRURGICHE, Da definire, and AREA MIN. 06 - Scienze mediche

Subjects
Stable angina, Ticagrelor, Prasugrel, Stent thrombosi, Stent thrombosis, medicine.medical_treatment, Vascular damage Radboud Institute for Health Sciences [Radboudumc 16], Coronary artery bypass grafting, 030204 cardiovascular system & hematology, Guideline, Coronary artery disease, Percutaneous coronary intervention, 0302 clinical medicine, Stent, DAPT score, 030212 general & internal medicine, Myocardial infarction, Drug-eluting stents, reproductive and urinary physiology, Societies, Medical, dual antiplatelet therapy, coronary artery disease, General Medicine, Clopidogrel, Europe, Cardiothoracic surgery, Non cardiac surgery, embryonic structures, Dual antiplatelet therapy, Cardiology, Stents, Stable coronary artery disease, Radiology, Acute coronary syndrome, biological phenomena, cell phenomena, and immunity, Cardiology and Cardiovascular Medicine, PRECISE-DAPT score, circulatory and respiratory physiology, medicine.drug, Pulmonary and Respiratory Medicine, medicine.medical_specialty, Acute coronary syndromes, Guidelines, 03 medical and health sciences, Non-cardiac surgery, Internal medicine, medicine, Humans, cardiovascular diseases, Triple therapy, Risk stratification, Aspirin, business.industry, urogenital system, Revascularization, Bleeding, Oral anticoagulant, Recommendation, medicine.disease, Settore MED/11 - MALATTIE DELL'APPARATO CARDIOVASCOLARE, Surgery, Drug-eluting stent, business, Platelet Aggregation Inhibitors
Abstract

none 107 si Non presente mixed Valgimigli, Marco*; Bueno, Héctor; Byrne, Robert A.; Collet, Jean-Philippe; Costa, Francesco; Jeppsson, Anders; Kastrati, Adnan; Kolh, Philippe; Mauri, Laura; Montalescot, Gilles; Neumann, Franz-Josef; Petricevic, Mate; Roffi, Marco; Steg, Philippe Gabriel; Zamorano, Jose Luis; Levine, Glenn N.; Badimon, Lina; Vranckx, Pascal; Agewall, Stefan; Andreotti, Felicita; Antman, Elliott; Barbato, Emanuele; Bassand, Jean-Pierre; Bugiardini, Raffaele; Cikirikcioglu, Mustafa; Cuisset, Thomas; De Bonis, Michele; Delgado, Victora; Fitzsimons, Donna; Galiè, Nazzareno; Gilard, Martine; Hamm, Christian W.; Ibanez, Borja; James, Stefan; Knuuti, Juhani; Landmesser, Ulf; Leclercq, Christophe; Lettino, Maddalena; Lip, Gregory; Piepoli, Massimo Francesco; Pierard, Luc; Schwerzmann, Markus; Sechtem, Udo; Simpson, Iain A.; Uva, Miguel Sousa; Stabile, Eugenio; Storey, Robert F.; Tendera, Michal; Van De Werf, Frans; Verheugt, Freek; Aboyans, Victor; Windecker, Stephan; Coca, Antonio; Coman, Ioan Mircea; Dean, Veronica; Delgado, Victoria; Gaemperli, Oliver; Hindricks, Gerhard; Iung, Bernard; Jüni, Peter; Katus, Hugo A.; Lancellotti, Patrizio; McDonagh, Theresa; Ponikowski, Piotr; Richter, DImitrios J.; Shlyakhto, Evgeny; Roithinger, Franz Xaver; Aliyev, Farid; Stelmashok, Valeriy; Desmet, Walter; Postadzhiyan, Arman; Georghiou, Georgios P.; Motovska, Zuzana; Grove, Erik Lerkevang; Marandi, Toomas; Kiviniemi, Tuomas; Kedev, Sasko; Massberg, Steffen; Alexopoulos, DImitrios; Kiss, Robert Gabor; Gudmundsdottir, Ingibjorg Jona; McFadden, Eugène P.; Lev, Eli; De Luca, Leonardo; Sugraliyev, Akhmetzhan; Haliti, Edmond; Mirrakhimov, Erkin; Latkovskis, Gustavs; Petrauskiene, Birute; Huijnen, Steve; Magri, Caroline Jane; Cherradi, Rhizlan; Ten Berg, Jurrien M.; Eritsland, Jan; Budaj, Andrzej; Aguiar, Carlos Tavares; Duplyakov, Dmitry; Zavatta, Marco; Antonijevic, Nebojsa M.; Fras, Zlatko; Montoliu, Antonio Tello; Varenhorst, Christoph; Tsakiris, DImitri; Addad, Faouzi; Aydogdu, Sinan; Parkhomenko, Alexander; Kinnaird, Tim Valgimigli, Marco*; Bueno, Héctor; Byrne, Robert A.; Collet, Jean-Philippe; Costa, Francesco; Jeppsson, Anders; Kastrati, Adnan; Kolh, Philippe; Mauri, Laura; Montalescot, Gilles; Neumann, Franz-Josef; Petricevic, Mate; Roffi, Marco; Steg, Philippe Gabriel; Zamorano, Jose Luis; Levine, Glenn N.; Badimon, Lina; Vranckx, Pascal; Agewall, Stefan; Andreotti, Felicita; Antman, Elliott; Barbato, Emanuele; Bassand, Jean-Pierre; Bugiardini, Raffaele; Cikirikcioglu, Mustafa; Cuisset, Thomas; De Bonis, Michele; Delgado, Victora; Fitzsimons, Donna; Galiè, Nazzareno; Gilard, Martine; Hamm, Christian W.; Ibanez, Borja; James, Stefan; Knuuti, Juhani; Landmesser, Ulf; Leclercq, Christophe; Lettino, Maddalena; Lip, Gregory; Piepoli, Massimo Francesco; Pierard, Luc; Schwerzmann, Markus; Sechtem, Udo; Simpson, Iain A.; Uva, Miguel Sousa; Stabile, Eugenio; Storey, Robert F.; Tendera, Michal; Van De Werf, Frans; Verheugt, Freek; Aboyans, Victor; Windecker, Stephan; Coca, Antonio; Coman, Ioan Mircea; Dean, Veronica; Delgado, Victoria; Gaemperli, Oliver; Hindricks, Gerhard; Iung, Bernard; Jüni, Peter; Katus, Hugo A.; Lancellotti, Patrizio; McDonagh, Theresa; Ponikowski, Piotr; Richter, DImitrios J.; Shlyakhto, Evgeny; Roithinger, Franz Xaver; Aliyev, Farid; Stelmashok, Valeriy; Desmet, Walter; Postadzhiyan, Arman; Georghiou, Georgios P.; Motovska, Zuzana; Grove, Erik Lerkevang; Marandi, Toomas; Kiviniemi, Tuomas; Kedev, Sasko; Massberg, Steffen; Alexopoulos, DImitrios; Kiss, Robert Gabor; Gudmundsdottir, Ingibjorg Jona; McFadden, Eugène P.; Lev, Eli; De Luca, Leonardo; Sugraliyev, Akhmetzhan; Haliti, Edmond; Mirrakhimov, Erkin; Latkovskis, Gustavs; Petrauskiene, Birute; Huijnen, Steve; Magri, Caroline Jane; Cherradi, Rhizlan; Ten Berg, Jurrien M.; Eritsland, Jan; Budaj, Andrzej; Aguiar, Carlos Tavares; Duplyakov, Dmitry; Zavatta, Marco; Antonijevic, Nebojsa M.; Fras, Zlatko; Montoliu, Antonio Tello; Varenhorst, Christoph; Tsakiris, DImitri; Addad, Faouzi; Aydogdu, Sinan; Parkhomenko, Alexander; Kinnaird, Tim

Published
2018

5. Improvement of migraine headaches after percutaneous closure of patent foramen ovale for secondary prevention of paradoxical embolism.

Author

Wahl, Andreas, Praz, Fabien, Tai, Tony, Findling, Oliver, Walpoth, Nazan, Nedeltchev, Krassen, Schwerzmann, Markus, Windecker, Stephan, Mattle, Heinrich P., and Meier, Bernhard

Subjects
PATENT foramen ovale, ANEURYSMS, MIGRAINE, MIGRAINE aura, CEREBRAL ischemia, PARADOXICAL embolism, CEREBROVASCULAR disease, CARDIOLOGY
Abstract

Objectives Patent foramen ovale (PFO) has been linked to migraine, and an improvement in migraine prevalence or frequency has been reported after PFO closure for other reasons. We sought to identify whether there is a specific patient population of migraineurs which may be more susceptible to benefiting from PFO closure. Design Retrospective cohort study. Setting Tertiary care centre. Participants 603 consecutive patients undergoing percutaneous PFO closure for secondary prevention of paradoxical embolism. Interventions PFO closure using the Amplatzer PFO occluder. Main outcome measures Improvement of migraine symptoms. Results 150 patients (25%; aged 51±11 years) suffered from migraine, including 96 patients with migraine with aura. All implantation procedures were successful, without procedural complications. Contrast transoesophageal echocardiography at 6 months showed complete PFO closure in 136 patients (91%), whereas a minimal, moderate or large residual shunt persisted in 11 (7%), 2 (1%) or 1 (1%) patients, respectively. During 5.0±1.9 years of follow-up, one TIA and one ischaemic stroke occurred. Migraine headaches disappeared in 51 patients (34%) and improved in 72 additional patients (48%). Mean subjective improvement was 69±35%. Overall, mean headache frequency (from 2∧3í/month to 1í/month; p<0.001), duration (from 4-72 to <4 h; p<0.001) and intensity (from 7±2 to 3±3; p<0.001) improved significantly. The prevalence of any migraine headaches (from 100% to 66%; p<0.001), migraine with aura (from 64% to 19%; p<0.001) and the number of patients taking any migraine medication (from 90% to 50%; p<0.001) decreased significantly. Both the presence of aura (OR 3.2; 95%CI 1.3 to 8.2; p=0.014) and high pain intensity at baseline (pain scale >5; OR 3.3; 95%CI 1.3 to 8.4; p=0.013) were independent predictors of response to PFO closure. A residual shunt had no influence on migraine improvement (OR 0.6; 95%CI 0.1 to 2.3; p=0.42). Conclusions These results suggest that percutaneous PFO closure durably alters the spontaneous course of shunt-associated migraine, especially but not exclusively in case of migraine with aura. [ABSTRACT FROM AUTHOR]

Published
2010
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6. Impact of left ventricular hypertrophy late after aortic valve replacement for aortic stenosis on cardiovascular morbidity and mortality

Author

Zybach-Benz, Renate E., Aeschbacher, Beat C., and Schwerzmann, Markus

Subjects
*CARDIOLOGY, *MORTALITY, *LIFE sciences, *HUMAN biology
Abstract

Abstract: Aims: The goal of this study was to assess the prevalence of left ventricular (LV) hypertrophy in patients with aortic stenosis late (>6 months) after aortic valve replacement and its impact on cardiac-related morbidity and mortality. Methods and results: In a single tertiary centre, echocardiographic data of LV muscle mass were collected. Detailed information of medical history and angiographic data were gathered. Ninety-nine of 213 patients (46%) had LV hypertrophy late (mean 5.8±5.4 years) after aortic valve replacement. LV hypertrophy was associated with impaired exercise capacity, higher New York Heart Association dyspnoea class, a tendency for more frequent chest pain expressed as higher Canadian Cardiovascular Society class, and more rehospitalizations. 24% of patients with normal LV mass vs. 39% of patients with LV hypertrophy reported cardiac-related morbidity (p =0.04). In a multivariate logistic regression model, LV hypertrophy was an independent predictor of cardiac-related morbidity (odds ratio 2.31, 95% CI 1.08 to 5.41), after correction for gender, baseline ejection fraction, and coronary artery disease and its risk factors. Thirty seven deaths occurred during a total of 1959 patient years of follow-up (mean follow-up 9.6 years). Age at aortic valve replacement (hazard ratio 1.85, 95% CI 1.39 to 2.47, for every 5 years increase in age), coexisting coronary artery disease at the time of surgery (hazard ratio 3.36, 95% CI 1.31 to 8.62), and smoking (hazard ratio 4.82, 95% CI 1.72 to 13.45) were independent predictors of overall mortality late after surgery, but not LV hypertrophy. Conclusions: In patients with aortic valve replacement for isolated aortic stenosis, LV hypertrophy late after surgery is associated with increased morbidity. [Copyright &y& Elsevier]

Published
2006
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7. Cardiopulmonary adaptation to short-term high altitude exposure in adult Fontan patients

Author

Lukas D. Trachsel, Jean-Paul Schmid, Daniel Tobler, Christina Deluigi, Stephan Schenker, Prisca Eser, Kerstin Wustmann, Matthias Wilhelm, Roger Staempfli, Markus Schwerzmann, Corina Thomet, Matthias Greutmann, Dominik Stambach, University of Zurich, and Schwerzmann, Markus

Subjects
Adult, Heart Defects, Congenital, Male, Pulmonary Circulation, medicine.medical_specialty, Time Factors, Acclimatization, medicine.medical_treatment, 610 Medicine & health, 030204 cardiovascular system & hematology, Fontan Procedure, 2705 Cardiology and Cardiovascular Medicine, Fontan procedure, Young Adult, 03 medical and health sciences, 0302 clinical medicine, Hypoxic pulmonary vasoconstriction, medicine.artery, Internal medicine, medicine, Humans, 030212 general & internal medicine, Exercise Tolerance, business.industry, Altitude, VO2 max, Hypoxia (medical), Effects of high altitude on humans, Treatment Outcome, medicine.anatomical_structure, Breath Tests, Ventricle, Case-Control Studies, Pulmonary artery, Circulatory system, Exercise Test, 10209 Clinic for Cardiology, Cardiology, Female, medicine.symptom, Cardiology and Cardiovascular Medicine, business
Abstract

OBJECTIVE High altitude-related hypoxia induces pulmonary vasoconstriction. In Fontan patients without a contractile subpulmonary ventricle, an increase in pulmonary artery pressure is expected to decrease circulatory output and reduce exercise capacity. This study investigates the direct effects of short-term high altitude exposure on pulmonary blood flow (PBF) and exercise capacity in Fontan patients. METHODS 16 adult Fontan patients (mean age 28±7 years, 56% female) and 14 matched controls underwent cardiopulmonary exercise testing with measurement of PBF with a gas rebreathing system at 540 m (low altitude) and at 3454 m (high altitude) within 12 weeks. RESULTS PBF at rest and at exercise was higher in controls than in Fontan patients, both at low and high altitude. PBF increased twofold in Fontan patients and 2.8-fold in the control group during submaximal exercise, with no significant difference between low and high altitude (p=0.290). A reduction in peak oxygen uptake at high compared with low altitude was observed in Fontan patients (22.8±5.1 and 20.5±3.8 mL/min/kg, p

Published
2016
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