1. Opportunities for improving cardiovascular health outcomes in adults younger than 65 years with guideline-recommended statin therapy.
- Author
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Sarasua SM, Li J, Hernandez GT, Ferdinand KC, Tobin JN, Fiscella KA, Jones DW, Sinopoli A, and Egan BM
- Subjects
- Adult, Aged, American Heart Association, Atherosclerosis epidemiology, Atherosclerosis mortality, Cardiovascular Diseases epidemiology, Cardiovascular Diseases mortality, Cholesterol blood, Eligibility Determination statistics & numerical data, Ethnicity, Female, Humans, Hypolipidemic Agents therapeutic use, Male, Middle Aged, Nutrition Surveys, Practice Guidelines as Topic, Risk Factors, United States epidemiology, Young Adult, Atherosclerosis complications, Cardiovascular Diseases drug therapy, Cardiovascular Diseases prevention & control, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use, Outcome Assessment, Health Care methods
- Abstract
The impact of age, race/ethnicity, healthcare insurance, and selected clinical variables on statin-preventable ASCVD were quantified in adults aged 21 to 79 years from National Health and Nutrition Examination Surveys 2007-2012 using the 2013 American College of Cardiology/American Heart Association guideline on the treatment of cholesterol. Among ≈42.4 million statin-eligible, untreated adults, 52.6% were hypertensive and 71% were younger than 65 years. Of ≈232 000 statin-preventable ASCVD events annually, most occur in individuals younger than 65 years, with higher proportions in blacks and Hispanics than whites (73.0% and 69.2% vs 56.9%, respectively; P<.01). Among adults younger than 65 years, the ratio of statin-eligible but untreated to statin-treated adults was higher in blacks and Hispanics than whites (3.0 and 2.9 vs 1.3, respectively; P<.01), and blacks, men, hypertensives, and cigarette smokers were more likely to be statin eligible than their statin-ineligible counterparts by multivariable logistic regression. Two thirds of untreated statin-eligible adults had two or more healthcare visits per year. Identifying and treating more statin-eligible adults in the healthcare system could improve cardiovascular health equity., (©2017 Wiley Periodicals, Inc.)
- Published
- 2017
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