26 results on '"Wood, DA"'
Search Results
2. Cardiovascular Care Delivery During the Second Wave of COVID-19 in Canada.
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Roifman I, Arora RC, Bewick D, Chow CM, Clarke B, Cowan S, Ducharme A, Gin K, Graham M, Gupta A, Hardiman S, Hartleib M, Jackson S, Jassal D, Kazmi M, Lamarche Y, Légaré JF, Leong-Poi H, Mansour S, Marelli A, Ruel M, Small G, Sterns L, Turgeon R, Virani S, Wijeysundera HC, Wong K, Wood DA, Zieroth S, Singh G, and Krahn AD
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- Canada epidemiology, Cardiovascular Diseases epidemiology, Comorbidity, Humans, COVID-19 epidemiology, Cardiovascular Diseases therapy, Critical Care methods, Delivery of Health Care organization & administration, Pandemics
- Abstract
Hospitals and ambulatory facilities significantly reduced cardiac care delivery in response to the first wave of the COVID-19 pandemic. The deferral of elective cardiovascular procedures led to a marked reduction in health care delivery with a significant impact on optimal cardiovascular care. International and Canadian data have reported dramatically increased wait times for diagnostic tests and cardiovascular procedures, as well as associated increased cardiovascular morbidity and mortality. In the wake of the demonstrated ability to rapidly create critical care and hospital ward capacity, we advocate a different approach during the second and possible subsequent COVID-19 pandemic waves. We suggest an approach, informed by local data and experience, that balances the need for an expected rise in demand for health care resources to ensure appropriate COVID-19 surge capacity with continued delivery of essential cardiovascular care. Incorporating cardiovascular care leaders into pandemic planning and operations will help health care systems minimise cardiac care delivery disruptions while maintaining critical care and hospital ward surge capacity and continuing measures to reduce transmission risk in health care settings. Specific recommendations targeting the main pillars of cardiovascular care are presented: ambulatory, inpatient, procedural, diagnostic, surgical, and rehabilitation., (Copyright © 2020 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.)
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- 2021
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3. Cardiac Rehabilitation During the COVID-19 Era: Guidance on Implementing Virtual Care.
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Moulson N, Bewick D, Selway T, Harris J, Suskin N, Oh P, Coutinho T, Singh G, Chow CM, Clarke B, Cowan S, Fordyce CB, Fournier A, Gin K, Gupta A, Hardiman S, Jackson S, Lamarche Y, Lau B, Légaré JF, Leong-Poi H, Mansour S, Marelli A, Quraishi AUR, Roifman I, Ruel M, Sapp J, Small G, Turgeon R, Wood DA, Zieroth S, Virani S, and Krahn AD
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- Betacoronavirus, COVID-19, Canada, Humans, Infection Control organization & administration, Models, Organizational, Organizational Innovation, Risk Assessment, SARS-CoV-2, Cardiac Rehabilitation methods, Cardiac Rehabilitation trends, Cardiovascular Diseases epidemiology, Cardiovascular Diseases prevention & control, Coronavirus Infections epidemiology, Coronavirus Infections prevention & control, Pandemics prevention & control, Pneumonia, Viral epidemiology, Pneumonia, Viral prevention & control, Telerehabilitation methods, Telerehabilitation organization & administration
- Abstract
Cardiac rehabilitation programs across Canada have suspended in-person services as a result of large-scale physical distancing recommendations designed to flatten the COVID-19 pandemic curve. Virtual cardiac rehabilitation (VCR) offers an alternate mechanism of care delivery, capable of providing similar patient outcomes and safety profiles compared with centre-based programs. To minimize care gaps, all centres should consider developing and implementing a VCR program. The process of this rapid implementation, however, can be daunting. Centres should initially focus on the collation, utilization, and repurposing of existing resources, equipment, and technology. Once established, programs should then focus on ensuring that quality indicators are met and care processes are protocolized. This should be followed by the development of sustainable VCR solutions to account for care gaps that existed before COVID-19, and to improve cardiac rehabilitation delivery, moving forward. This article reviews the potential challenges and obstacles of this process and aims to provide pragmatic guidance to aid clinicians and administrators during this challenging time., (Copyright © 2020 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.)
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- 2020
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4. Guiding Cardiac Care During the COVID-19 Pandemic: How Ethics Shapes Our Health System Response.
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Virani A, Singh G, Bewick D, Chow CM, Clarke B, Cowan S, Fordyce CB, Fournier A, Gin K, Gupta A, Hardiman S, Jackson S, Lamarche Y, Lau B, Légaré JF, Leong-Poi H, Mansour S, Marelli A, Quraishi A, Roifman I, Ruel M, John Sapp, Small G, Turgeon R, Wood DA, Zieroth S, Virani S, and Krahn AD
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- Betacoronavirus isolation & purification, COVID-19, Canada epidemiology, Humans, Models, Organizational, Organizational Innovation, SARS-CoV-2, Cardiology Service, Hospital organization & administration, Cardiology Service, Hospital trends, Cardiovascular Diseases epidemiology, Cardiovascular Diseases therapy, Coronavirus Infections epidemiology, Coronavirus Infections prevention & control, Ethics, Institutional, Infection Control methods, Pandemics prevention & control, Patient Care Management ethics, Patient Care Management methods, Patient Care Management standards, Pneumonia, Viral epidemiology, Pneumonia, Viral prevention & control
- Abstract
The COVID-19 pandemic has raised ethical questions for the cardiovascular leader and practitioner. Attention has been redirected from a system that focuses on individual patient benefit toward one that focuses on protecting society as a whole. Challenging resource allocation questions highlight the need for a clearly articulated ethics framework that integrates principled decision making into how different cardiovascular care services are prioritized. A practical application of the principles of harm minimisation, fairness, proportionality, respect, reciprocity, flexibility, and procedural justice is provided, and a model for prioritisation of the restoration of cardiovascular services is outlined. The prioritisation model may be used to determine how and when cardiovascular services should be continued or restored. There should be a focus on an iterative and responsive approach to broader health care system needs, such as other disease groups and local outbreaks., (Copyright © 2020 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.)
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- 2020
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5. Management of Cardiovascular Disease Patients With Confirmed or Suspected COVID-19 in Limited Resource Settings.
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Prabhakaran D, Perel P, Roy A, Singh K, Raspail L, Faria-Neto JR, Gidding SS, Ojji D, Hakim F, Newby LK, Stępińska J, Lam CSP, Jobe M, Kraus S, Chuquiure-Valenzuela E, Piñeiro D, Khaw KT, Bahiru E, Banerjee A, Narula J, Pinto FJ, Wood DA, and Sliwa K
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- COVID-19, Clinical Decision-Making, Decision Trees, Health Resources, Humans, Pandemics, Practice Guidelines as Topic, Cardiovascular Diseases complications, Cardiovascular Diseases therapy, Coronavirus Infections complications, Pneumonia, Viral complications
- Abstract
In this paper, we provide recommendations on the management of cardiovascular disease (CVD) among patients with confirmed or suspected coronavirus disease (COVID-19) to facilitate the decision making of healthcare professionals in low resource settings. The emergence of novel coronavirus disease, also known as Severe Acute Respiratory Syndrome-Coronavirus-2 (SARS-CoV-2), has presented an unprecedented global challenge for the healthcare community. The ability of SARS-CoV-2 to get transmitted during the asymptomatic phase and its high infectivity have led to the rapid transmission of COVID-19 beyond geographic regions, leading to a pandemic. There is concern that COVID-19 is cardiotropic, and it interacts with the cardiovascular system on multiple levels. Individuals with established CVD are more susceptible to severe COVID-19. Through a consensus approach involving an international group this WHF statement summarizes the links between cardiovascular disease and COVID-19 and present some practical recommendations for the management of hypertension and diabetes, acute coronary syndrome, heart failure, rheumatic heart disease, Chagas disease, and myocardial injury for patients with COVID-19 in low-resource settings. This document is not a clinical guideline and it is not intended to replace national clinical guidelines or recommendations. Given the rapidly growing burden posed by COVID-19 illness and the associated severe prognostic implication of CVD involvement, further research is required to understand the potential mechanisms linking COVID-19 and CVD, clinical presentation, and outcomes of various cardiovascular manifestations in COVID-19 patients., Competing Interests: The authors have no competing interests to declare., (Copyright: © 2020 The Author(s).)
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- 2020
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6. What Is the Best Mix of Population-Wide and High-Risk Targeted Strategies of Primary Stroke and Cardiovascular Disease Prevention?
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Feigin VL, Brainin M, Norrving B, Gorelick PB, Dichgans M, Wang W, Pandian JD, Martins SCO, Owolabi MO, Wood DA, and Hankey GJ
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- Cardiovascular Diseases economics, Cardiovascular Diseases epidemiology, Cardiovascular Diseases mortality, Health Care Costs, Health Policy, Heart Disease Risk Factors, Humans, Policy Making, Predictive Value of Tests, Prognosis, Protective Factors, Risk Assessment, Stroke economics, Stroke epidemiology, Stroke mortality, Uncertainty, Cardiovascular Diseases prevention & control, Primary Prevention economics, Primary Prevention legislation & jurisprudence, Stroke prevention & control
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- 2020
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7. Clinical Conference Proceedings: 15th Biennial International Andreas Gruentzig Society Meeting.
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Anderson HV, Bersin RM, Abbott JD, Aronow HD, Bass TA, Brilakis ES, Cavaye DM, Cohen MG, Dean LS, Dippel EJ, Garratt KN, Greenbaum AB, Hanzel GS, Helmy T, Lerman A, Magd AA, Marshall JJ, Medigo A, Mooney MR, Naidu SS, O'Neill B, Pichard AD, Rinaldi MJ, Sorajja P, Szerlip MA, Wood DA, and Zidar JP
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- Humans, Cardiology methods, Cardiovascular Diseases therapy, Congresses as Topic, Societies, Medical
- Abstract
The International Andreas Gruentzig Society is an educational society of physicians and scientists interested in cardiovascular and related fields. Members cooperate in the advancement of knowledge and education through research, publication, study, and teaching in the fields of cardiovascular disease. This summary reflects the proceedings from the recent scientific meeting to assess current clinical problems and propose future directions and possible solutions.
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- 2019
8. The rise and fall of aspirin in the primary prevention of cardiovascular disease.
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Raber I, McCarthy CP, Vaduganathan M, Bhatt DL, Wood DA, Cleland JGF, Blumenthal RS, and McEvoy JW
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- Adult, Aged, Aged, 80 and over, Aspirin pharmacology, Clinical Trials as Topic, Cyclooxygenase Inhibitors pharmacology, Diabetic Angiopathies prevention & control, Female, Humans, Male, Middle Aged, Platelet Aggregation Inhibitors pharmacology, Primary Prevention, Sex Factors, Aspirin therapeutic use, Cardiovascular Diseases prevention & control, Cyclooxygenase Inhibitors therapeutic use, Platelet Aggregation Inhibitors therapeutic use
- Abstract
Aspirin is one of the most frequently used drugs worldwide and is generally considered effective for the secondary prevention of cardiovascular disease. By contrast, the role of aspirin in primary prevention of cardiovascular disease is controversial. Early trials evaluating aspirin for primary prevention, done before the turn of the millennium, suggested reductions in myocardial infarction and stroke (although not mortality), and an increased risk of bleeding. In an effort to balance the risks and benefits of aspirin, international guidelines on primary prevention of cardiovascular disease have typically recommended aspirin only when a substantial 10-year risk of cardiovascular events exists. However, in 2018, three large randomised clinical trials of aspirin for the primary prevention of cardiovascular disease showed little or no benefit and have even suggested net harm. In this narrative Review, we reappraise the role of aspirin in primary prevention of cardiovascular disease, contextualising data from historical and contemporary trials., (Copyright © 2019 Elsevier Ltd. All rights reserved.)
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- 2019
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9. Reconfiguring Cardiac Rehabilitation to Achieve Panvascular Prevention: New Care Models for a New World.
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Sandesara PB, Dhindsa D, Khambhati J, Lee SK, Varghese T, O'Neal WT, Harzand A, Gaita D, Kotseva K, Connolly SB, Jennings C, Grace SL, Wood DA, and Sperling L
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- Cardiovascular Agents therapeutic use, Global Health, Humans, Models, Organizational, Risk Factors, Risk Reduction Behavior, Survival Analysis, Cardiac Rehabilitation methods, Cardiovascular Diseases mortality, Cardiovascular Diseases prevention & control, Cardiovascular Diseases psychology, Delivery of Health Care, Integrated organization & administration, Quality of Life, Secondary Prevention methods
- Abstract
Atherosclerotic cardiovascular disease (ASCVD) and its associated economic burden are increasing globally. Although cardiac rehabilitation is a vital component of secondary prevention with proven benefits, it is underutilized due to numerous barriers, especially in resource-limited settings. New care models for delivery of comprehensive prevention programs such as community-based, home-based, and "hybrid" models implementing m-health, e-health, and telemedicine need to be adopted. Such new care models should be offered to all patients with established ASCVD (coronary, cerebral, and peripheral) and additionally to those at high risk of developing ASCVD with multiple risk factors for panvascular prevention., (Copyright © 2018 Canadian Cardiovascular Society. Published by Elsevier Inc. All rights reserved.)
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- 2018
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10. The 2000-2016 WHF Global Atlas of CVD: Take Two.
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Moran AE, Wood DA, and Narula J
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- Global Health, Humans, Morbidity trends, Cardiology, Cardiovascular Diseases epidemiology, Cardiovascular Diseases etiology, Cardiovascular Diseases prevention & control, Practice Guidelines as Topic, Primary Prevention standards, Societies, Medical
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- 2018
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11. CardioScape mapping the cardiovascular funding landscape in Europe.
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Pries AR, Naoum A, Habazettl H, Dunkel M, Preissner R, Coats CJ, Tornada A, Orso F, Van de Werf F, Wood DA, Van de Werf F, Wood DA, O'Kelly S, Craven J, Coats A, Sipido K, De Backer D, Wallentin L, Hasenfuss G, Della Sala L, Leggeri I, Wood DA, Van de Werf F, Jaarsma T, Elliott P, Pries AR, Madonna R, Kjeldsen K, Maggioni AP, Franco OH, Hills S, Pugliese F, and De Bacquer D
- Subjects
- Europe, European Union, Humans, Biomedical Research economics, Cardiovascular Diseases, Financial Management
- Abstract
Aims: The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transformed into an on-line and up-to-date resource of great relevance for researchers, funding bodies and policymakers and could be a role model for mapping CV research funding in Europe and beyond., Methods and Results: Relevant funding bodies in 28 European Union (EU) countries were identified by a multistep process involving experts in each country. Projects above a funding threshold of 100 k€ during the period 2010-2012 were included using a standard questionnaire. Results were classified by experts and an adaptive text analysis software to a CV-research taxonomy, integrating existing schemes from ESC journals and congresses. An on-line query portal was set up to allow different users to interrogate the database according to their specific viewpoints., Conclusion: CV-research funding varies strongly between different nations with the EU providing 37% of total available project funding and clear geographical gradients exist. Data allow in depth comparison of funding for different research areas and led to a number of recommendations by the consortium. CardioScape can support CV research by aiding researchers, funding agencies and policy makers in their strategic decisions thus improving research quality if CardioScape strategy and technology becomes the basis of a continuously updated and expanded European wide publicly accessible database.
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- 2018
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12. Prevalence of cardiometabolic risk factors among professional male long-distance bus drivers in Lagos, south-west Nigeria: a cross-sectional study.
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Amadi CE, Grove TP, Mbakwem AC, Ozoh OB, Kushimo OA, Wood DA, and Akinkunmi M
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- Adult, Alcohol Drinking adverse effects, Alcohol Drinking epidemiology, Cardiovascular Diseases diagnosis, Cross-Sectional Studies, Diabetes Mellitus diagnosis, Diabetes Mellitus epidemiology, Dyslipidemias diagnosis, Dyslipidemias epidemiology, Health Status, Health Surveys, Humans, Hypertension diagnosis, Hypertension epidemiology, Job Description, Male, Metabolic Syndrome diagnosis, Middle Aged, Nigeria epidemiology, Obesity diagnosis, Obesity epidemiology, Occupational Diseases diagnosis, Prevalence, Risk Factors, Sedentary Behavior, Sitting Position, Smoking adverse effects, Smoking epidemiology, Time Factors, Automobile Driving, Cardiovascular Diseases epidemiology, Metabolic Syndrome epidemiology, Occupational Diseases epidemiology, Occupational Health, Occupations
- Abstract
Background: Professional drivers are known to be at high risk of cardiovascular disease (CVD). This study was carried out to highlight these risk factors and their predictors among male long-distance professional bus drivers in Lagos, south-west Nigeria, with a view to improving health awareness in this group., Method: Socio-demographic data, anthropometric indices, blood pressure, fasting plasma blood glucose levels and lipid and physical activity profiles of 293 drivers were measured., Results: Mean age of the study population was 48 ± 9.7 years; 71.0 and 19.5% of the drivers used alcohol and were smokers, respectively; and 50.9% were physically inactive. The prevalence of overweight and obesity was 41.7 and 21.1%, respectively, while 39.7 and 13.9% were hypertensive and diabetic, respectively. Ninety (31.3%) subjects had impaired fasting glucose levels while 56.3% had dyslipidaemia. Predictors of hypertension were age and body mass index (BMI). BMI only was a predictor of abnormal glucose profile., Conclusion: Professional male long-distance bus drivers in this study showed a high prevalence of a cluster of risk factors for CVD.
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- 2018
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13. A cross-sectional survey of cardiovascular health and lifestyle habits of hospital staff in the UK: Do we look after ourselves?
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Mittal TK, Cleghorn CL, Cade JE, Barr S, Grove T, Bassett P, Wood DA, and Kotseva K
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- Adult, Body Mass Index, Cardiovascular Diseases epidemiology, Cardiovascular Diseases etiology, Cross-Sectional Studies, Feeding Behavior, Female, Humans, Incidence, Male, Middle Aged, Overweight complications, Overweight epidemiology, Prevalence, Self Report, United Kingdom epidemiology, Cardiovascular Diseases prevention & control, Exercise physiology, Healthy Lifestyle physiology, Life Style, Medical Staff, Hospital, Overweight prevention & control, Surveys and Questionnaires
- Abstract
Background A high prevalence of stress-related disorders is well known among healthcare professionals. We set out to assess the prevalence of cardiovascular risk factors and compliance with national dietary and physical activity recommendations in NHS staff in the UK with comparison between clinical and non-clinical staff, and national surveys. Design A multi-centre cross-sectional study. Methods A web-based questionnaire was developed to include anonymised data on demographics, job role, cardiovascular risk factors and diseases, dietary habits, physical activity and barriers towards healthy lifestyle. This was distributed to staff in four NHS hospitals via emails. Results A total of 1158 staff completed the survey (response rate 13%) with equal distribution between the clinical and non-clinical groups. Most staff were aged 26-60 years and 79% were women. Half of the staff were either overweight or obese (51%) with no difference between the groups ( P = 0.176), but there was a lower prevalence of cardiovascular risk factors compared to the general population. The survey revealed a low compliance (17%) with the recommended intake of five-a-day portions of fruit and vegetables, and that of moderate or vigorous physical activity (56%), with no difference between the clinical and non-clinical staff ( P = 0.6). However, more clinical staff were exceeding the alcohol recommendations ( P = 0.02). Lack of fitness facilities and managerial support, coupled with long working hours, were the main reported barriers to a healthy lifestyle. Conclusions In this survey of UK NHS staff, half were found to be overweight or obese with a lower prevalence of cardiovascular risk factors compared to the general population. There was a low compliance with the five-a-day fruit and vegetables recommendation and physical activity guidelines, with no difference between the clinical and non-clinical staff.
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- 2018
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14. Outcomes of an integrated community-based nurse-led cardiovascular disease prevention programme.
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Connolly SB, Kotseva K, Jennings C, Atrey A, Jones J, Brown A, Bassett P, and Wood DA
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- Cardiovascular Diseases nursing, Female, Humans, Male, Middle Aged, Retrospective Studies, Risk Factors, Cardiac Rehabilitation nursing, Cardiovascular Diseases prevention & control, Community Health Services methods, Life Style, Patient Compliance, Program Evaluation methods, Risk Reduction Behavior
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Background: National guidance for England recommends that cardiovascular disease (CVD) should be managed as a family of diseases in the community. Here, we describe the results of such an approach., Methods: Patients with established CVD or who were at high multifactorial risk (HRI) underwent a 12-week community-based nurse-led prevention programme (MyAction) that included lifestyle and risk factor management, prescription of medication and weekly exercise and education sessions., Results: Over a 6-year period, 3232 patients attended an initial assessment; 63% were male, and 48% belonged to black and minority ethnic groups. 56% attended an end-of-programme assessment, and 33% attended a one year assessment. By the end of the programme, there was a significant reduction in smoking prevalence but only in HRI (-3.7%, p<0.001). Mediterranean diet score increased in both CVD (+1.2, p<0.001) and HRI (+1.5; p<0.001), as did fitness levels (CVD +0.8 estimated Mets maximum, p<0.001, HRI +0.9 estimated Mets maximum, p<0.001) and the proportions achieving their physical activity targets (CVD +40%, p<0.001, HRI +37%, p<0.001). There were significant increases in proportions achieving their blood pressure (CVD +15.4%, p<0.001, HRI +25%, p<0.001 and low-density lipoprotein cholesterol targets (CVD +6%, p=0.004, HRI +23%, p<0.001). Statins and antihypertensive medications significantly increased in HRI. Significant improvements in depression scores and quality-of-life measures were also seen. The majority of improvements were maintained at 1 year., Conclusion: These results demonstrate that an integrated vascular prevention programme is feasible in practice and reduces cardiovascular risk in patients with established CVD and in those at high multifactorial risk., Competing Interests: Competing interests: None declared., (© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2017. All rights reserved. No commercial use is permitted unless otherwise expressly granted.)
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- 2017
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15. 2016 ESC/EAS Guidelines for the Management of Dyslipidaemias.
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Catapano AL, Graham I, De Backer G, Wiklund O, Chapman MJ, Drexel H, Hoes AW, Jennings CS, Landmesser U, Pedersen TR, Reiner Ž, Riccardi G, Taskinen MR, Tokgozoglu L, Verschuren WMM, Vlachopoulos C, Wood DA, Zamorano JL, and Cooney MT
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- Cardiology, Cardiovascular Diseases etiology, Dyslipidemias complications, Europe, Humans, Risk, Sex Factors, Societies, Medical, Cardiovascular Diseases prevention & control, Dyslipidemias therapy
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- 2016
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16. The Heart of 25 by 25: Achieving the Goal of Reducing Global and Regional Premature Deaths From Cardiovascular Diseases and Stroke: A Modeling Study From the American Heart Association and World Heart Federation.
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Sacco RL, Roth GA, Reddy KS, Arnett DK, Bonita R, Gaziano TA, Heidenreich PA, Huffman MD, Mayosi BM, Mendis S, Murray CJ, Perel P, Piñeiro DJ, Smith SC Jr, Taubert KA, Wood DA, Zhao D, and Zoghbi WA
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- Adult, Age Factors, Aged, Cardiovascular Diseases diagnosis, Cause of Death, Female, Humans, Interdisciplinary Communication, Intersectoral Collaboration, Male, Middle Aged, Prognosis, Risk Assessment, Risk Factors, Stroke diagnosis, Time Factors, United States, American Heart Association, Cardiology trends, Cardiovascular Diseases mortality, Cardiovascular Diseases therapy, Global Health trends, Models, Cardiovascular, Stroke mortality, Stroke therapy
- Abstract
In 2011, the United Nations set key targets to reach by 2025 to reduce the risk of premature noncommunicable disease death by 25% by 2025. With cardiovascular disease being the largest contributor to global mortality, accounting for nearly half of the 36 million annual noncommunicable disease deaths, achieving the 2025 goal requires that cardiovascular disease and its risk factors be aggressively addressed. The Global Cardiovascular Disease Taskforce, comprising the World Heart Federation, American Heart Association, American College of Cardiology Foundation, European Heart Network, and European Society of Cardiology, with expanded representation from Asia, Africa, and Latin America, along with global cardiovascular disease experts, disseminates information and approaches to reach the United Nations 2025 targets. The writing committee, which reflects Global Cardiovascular Disease Taskforce membership, engaged the Institute for Health Metrics and Evaluation, University of Washington, to develop region-specific estimates of premature cardiovascular mortality in 2025 based on various scenarios. Results show that >5 million premature CVD deaths among men and 2.8 million among women are projected worldwide by 2025, which can be reduced to 3.5 million and 2.2 million, respectively, if risk factor targets for blood pressure, tobacco use, diabetes mellitus, and obesity are achieved. However, global risk factor targets have various effects, depending on region. For most regions, United Nations targets for reducing systolic blood pressure and tobacco use have more substantial effects on future scenarios compared with maintaining current levels of body mass index and fasting plasma glucose. However, preventing increases in body mass index has the largest effect in some high-income countries. An approach achieving reductions in multiple risk factors has the largest impact for almost all regions. Achieving these goals can be accomplished only if countries set priorities, implement cost-effective population wide strategies, and collaborate in public-private partnerships across multiple sectors., (© 2016 American Heart Association, Inc.)
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- 2016
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17. World Heart Federation Emerging Leaders Program: An Innovative Capacity Building Program to Facilitate the 25 × 25 Goal.
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Huffman MD, Perel P, Beller GA, Keightley L, Miranda JJ, Ralston J, Reddy KS, Wood DA, Labarthe DR, and Yusuf S
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- Biomedical Research organization & administration, Capacity Building, Cardiology education, Cardiovascular Diseases mortality, Education, Medical organization & administration, Feedback, Global Health, Humans, International Agencies, Internet, Interprofessional Relations, Leadership, Medical Informatics organization & administration, Mortality, Premature, Organizational Objectives, Cardiovascular Diseases prevention & control
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- 2015
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18. Sustainable Development Goals and the future of cardiovascular health. A statement from the Global Cardiovascular Disease Taskforce.
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Zoghbi WA, Duncan T, Antman E, Barbosa M, Champagne B, Chen D, Gamra H, Harold JG, Josephson S, Komajda M, Logstrup S, Jur C, Mayosi BM, Mwangi J, Ralston J, Sacco RL, Sim KH, Smith SC Jr, Vardas PE, and Wood DA
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- Global Health, Goals, Humans, International Cooperation, Universal Health Insurance, Cardiovascular Diseases prevention & control, Conservation of Natural Resources
- Published
- 2014
19. The CardioScape Project.
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Wood DA and Van de Werf F
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- Biomedical Research economics, Europe, Healthcare Disparities, Humans, Research Support as Topic, Biomedical Research statistics & numerical data, Cardiovascular Diseases epidemiology
- Published
- 2014
20. Moving from political declaration to action on reducing the global burden of cardiovascular diseases: a statement from the Global Cardiovascular Disease Taskforce.
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Smith SC Jr, Chen D, Collins A, Harold JG, Jessup M, Josephson S, Logstrup S, Sacco RL, Vardas PE, Wood DA, and Zoghbi WA
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- Cardiovascular Diseases mortality, Global Health, Health Behavior, Health Priorities organization & administration, Humans, Politics, United Nations, World Health Organization, Cardiovascular Diseases prevention & control
- Published
- 2013
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21. Our time: a call to save preventable death from cardiovascular disease (heart disease and stroke).
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Smith SC Jr, Collins A, Ferrari R, Holmes DR Jr, Logstrup S, McGhie DV, Ralston J, Sacco RL, Stam H, Taubert K, Wood DA, and Zoghbi WA
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- Cardiovascular Diseases prevention & control, Europe, Global Health trends, Humans, Societies, Medical trends, Stroke prevention & control, Time Factors, United States, American Heart Association, Cardiovascular Diseases mortality, Death, Stroke mortality, World Health Organization
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- 2012
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22. Nurse-coordinated multidisciplinary, family-based cardiovascular disease prevention programme (EUROACTION) for patients with coronary heart disease and asymptomatic individuals at high risk of cardiovascular disease: a paired, cluster-randomised controlled trial.
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Wood DA, Kotseva K, Connolly S, Jennings C, Mead A, Jones J, Holden A, De Bacquer D, Collier T, De Backer G, and Faergeman O
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- Aged, Antihypertensive Agents therapeutic use, Coronary Disease drug therapy, Diet, Family, Female, Humans, Hydroxymethylglutaryl-CoA Reductase Inhibitors therapeutic use, Male, Middle Aged, Patient Compliance, Risk Factors, Cardiovascular Diseases etiology, Cardiovascular Diseases prevention & control, Coronary Disease complications, Health Behavior, Health Promotion methods, Life Style, Nurse's Role
- Abstract
Background: Our aim was to investigate whether a nurse-coordinated multidisciplinary, family-based preventive cardiology programme could improve standards of preventive care in routine clinical practice., Methods: In a matched, cluster-randomised, controlled trial in eight European countries, six pairs of hospitals and six pairs of general practices were assigned to an intervention programme (INT) or usual care (UC) for patients with coronary heart disease or those at high risk of developing cardiovascular disease. The primary endpoints-measured at 1 year-were family-based lifestyle change; management of blood pressure, lipids, and blood glucose to target concentrations; and prescription of cardioprotective drugs. Analysis was by intention to treat. The trial is registered as ISRCTN 71715857., Findings: 1589 and 1499 patients with coronary heart disease in hospitals and 1189 and 1128 at high risk were assigned to INT and UC, respectively. In patients with coronary heart disease who smoked in the month before the event, 136 (58%) in the INT and 154 (47%) in the UC groups did not smoke 1 year afterwards (difference in change 10.4%, 95% CI -0.3 to 21.2, p=0.06). Reduced consumption of saturated fat (196 [55%] vs 168 [40%]; 17.3%, 6.4 to 28.2, p=0.009), and increased consumption of fruit and vegetables (680 [72%] vs 349 [35%]; 37.3%, 18.1 to 56.5, p=0.004), and oily fish (156 [17%] vs 81 [8%]; 8.9%, 0.3 to 17.5, p=0.04) at 1 year were greatest in the INT group. High-risk individuals and partners showed changes only for fruit and vegetables (p=0.005). Blood-pressure target of less than 140/90 mm Hg was attained by both coronary (615 [65%] vs 547 [55%]; 10.4%, 0.6 to 20.2, p=0.04) and high-risk (586 [58%] vs 407 [41%]; 16.9%, 2.0 to 31.8, p=0.03) patients in the INT groups. Achievement of total cholesterol of less than 5 mmol/L did not differ between groups, but in high-risk patients the difference in change from baseline to 1 year was 12.7% (2.4 to 23.0, p=0.02) in favour of INT. In the hospital group, prescriptions for statins were higher in the INT group (810 [86%] vs 794 [80%]; 6.0%, -0.5 to 11.5, p=0.04). In general practices in the intervention groups, angiotensin-converting enzyme inhibitors (297 [29%] INT vs 196 [20%] UC; 8.5%, 1.8 to 15.2, p=0.02) and statins (381 [37%] INT vs 232 [22%] UC; 14.6%, 2.5 to 26.7, p=0.03) were more frequently prescribed., Interpretation: To achieve the potential for cardiovascular prevention, we need local preventive cardiology programmes adapted to individual countries, which are accessible by all hospitals and general practices caring for coronary and high-risk patients.
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- 2008
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23. Principles for national and regional guidelines on cardiovascular disease prevention: a scientific statement from the World Heart and Stroke Forum.
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Smith SC Jr, Jackson R, Pearson TA, Fuster V, Yusuf S, Faergeman O, Wood DA, Alderman M, Horgan J, Home P, Hunn M, and Grundy SM
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- Adult, Age Factors, Aged, Algorithms, Arteriosclerosis epidemiology, Arteriosclerosis therapy, Blood Glucose analysis, Blood Pressure, Cardiovascular Diseases epidemiology, Cardiovascular Diseases genetics, Comorbidity, Cost-Benefit Analysis, Diet, Female, Health Policy, Humans, International Cooperation, Life Style, Lipids blood, Male, Middle Aged, Risk Assessment, Risk Factors, World Health Organization, Cardiovascular Diseases prevention & control, Practice Guidelines as Topic standards
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- 2004
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24. Alcohol consumption, metabolic cardiovascular risk factors and hypertension in women.
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Nanchahal K, Ashton WD, and Wood DA
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- Adult, Age Distribution, Cross-Sectional Studies, Female, Humans, Linear Models, Lipids blood, Logistic Models, Middle Aged, Odds Ratio, Prevalence, Risk Factors, United Kingdom epidemiology, Alcohol Drinking epidemiology, Cardiovascular Diseases prevention & control, Hypertension epidemiology
- Abstract
Background: Low to moderate alcohol consumption is associated with reduced mortality, primarily due to a reduction in coronary heart disease (CHD). Conversely, heavy drinking increases mortality, mainly due to haemorrhagic stroke and non-cardiovascular diseases. It is important to identify the threshold of alcohol consumption above which the balance of risk and benefit becomes adverse. We examine the relationship between reported alcohol consumption, cardiovascular disease (CVD) risk factors, a 10-year CHD risk score and hypertension in women., Methods: In all, 14 077 female employees aged 30-64 years, underwent screening for CVD risk factors. Information was available on a range of personal and lifestyle factors, including height, weight, blood pressure, lipids, lipoproteins, apolipoproteins and blood glucose. Age-adjusted means were computed for the risk factors in each of five groups of reported alcohol intake: <1 (non-drinkers), 1-7, 8-14, 15-21, > or = 22 units/week. The relationships between alcohol and a derived coronary risk score and hypertension were also examined., Results: Increasing consumption was associated with an age-adjusted increase in high density lipoprotein cholesterol (HDL-C) and apolipoprotein A1 (both P < 0.001), a decline in body mass index, total cholesterol (TC), TC/HDL-C ratio, low density lipoprotein cholesterol (LDL-C) and apolipoprotein B (all P < 0.001), and no trend in triglycerides (P = 0.06), lipoprotein (a) (P = 0.09) or fasting glucose (P = 0.14). Except for LDL-C (P = 0.06) the relationships remained statistically significant after adjustment for possible confounders. Compared to non-drinkers, there was a decrease in 10-year CHD risk with increasing consumption, with the greatest reduction in risk in women consuming 1-7 units/week, odds ratio (OR) = 0.79, (95% CI: 0.72-0.87), and an increase in the prevalence of hypertension among those consuming 15-21 units/week, OR = 1.68, (95% CI: 1.14-2.46)., Conclusions: This study provides biological support for an inverse association between alcohol intake and CHD in women, associated with favourable changes in lipid and lipoprotein risk factors. Women consuming 1-14 units/week had a reduction in CHD risk, but there was an increased prevalence of hypertension among those consuming > or = 15 units/week. These data suggest that, in terms of the reduced risk of CVD, women should be advised to restrict their alcohol consumption to < or = 14 units/week.
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- 2000
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25. A population survey of cardiovascular disease in elderly people: design, methods and prevalence results.
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Dewhurst G, Wood DA, Walker F, Lampe FC, Jeffreys M, Cooper M, and Williams JD
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- Age Factors, Aged, Aged, 80 and over, Cardiovascular Agents therapeutic use, Cardiovascular Diseases diagnosis, Cardiovascular Diseases drug therapy, Cardiovascular Diseases mortality, Cross-Sectional Studies, England epidemiology, Female, Humans, Male, Population Surveillance methods, Predictive Value of Tests, Sensitivity and Specificity, Sex Factors, Surveys and Questionnaires, World Health Organization, Cardiovascular Diseases epidemiology
- Abstract
A cross-sectional survey of an age- and sex-stratified random sample of the elderly population living in Southampton was undertaken with the object of measuring the frequency of cardiovascular disease by questionnaire and examination, and assessing cardiac anatomy and physiological function by noninvasive methods. The response rate was 64% and 259 men and women aged between 65 and 95 years were interviewed and examined and had a twelve-lead ECG and chest radiograph. Forty per cent of men and 47% of women reported a diagnosis of one or more cardiovascular diseases, of which high blood pressure 33%, coronary heart disease 14% (angina pectoris 11% and myocardial infarction 8%), peripheral arterial disease of the lower limbs 7%, and cerebrovascular disease 6% occurred most frequently. With the exception of high blood pressure, which women reported more frequently than men (40% vs 27%), the prevalence of these diagnoses by sex was similar. The self-administered WHO questionnaires gave point prevalence estimates for angina pectoris of 13%, possible myocardial infarction 7% and intermittent claudication 5%, which were similar to reported prevalences of these diseases, although disagreement in the classification of individuals for each disease was common. When comparing the WHO chest pain questionnaire with the doctors' independent diagnosis of angina pectoris in this population, the sensitivity of the WHO questionnaire was 79%, with a specificity of 98% and a predictive value of 88%. For each sex the sensitivity of the WHO chest pain questionnaire was similar but specificity and predictive value were both lower for women.(ABSTRACT TRUNCATED AT 250 WORDS)
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- 1991
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26. CardioScape mapping the cardiovascular funding landscape in Europe
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Pries, A. R., Naoum, A., Habazettl, H., Dunkel, M., Preissner, R., Coats, C. J., Tornada, A., Orso, F., Van de Werf, F., Wood, D. A., CardioScape steering committee, Van de Werf, F, Wood, Da, O'Kelly, S, Craven, J, Coats, A, Sipido, K, De Backer, D, Wallentin, L, Hasenfuss, G, Della Sala, L, Leggeri, I, CardioScape scientific committee, Jaarsma, T, Elliott, P, Pries, Ar, Madonna, R, Kjeldsen, K, Maggioni, Ap, Franco, Oh, Hills, S, Pugliese, F, and De Bacquer, D
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Cardiac & Cardiovascular Systems ,Biomedical Research ,Text mining ,Financial Management ,Funding policy, Funding agencies, Database, Cardiovascular research, Text mining, Biomedical Research, Europe, European Union, Humans, Cardiovascular Diseases, Financial Management ,Research areas ,Cardiovascular research ,Funding policy ,030204 cardiovascular system & hematology ,Funding agencies ,Database ,03 medical and health sciences ,0302 clinical medicine ,Role model ,Environmental health ,Humans ,media_common.cataloged_instance ,Medicine ,Research quality ,European Union ,European union ,media_common ,Science & Technology ,business.industry ,030229 sport sciences ,Public relations ,Viewpoints ,Europe ,Cardiovascular Diseases ,Cardiovascular System & Cardiology ,Cardiology and Cardiovascular Medicine ,business ,Life Sciences & Biomedicine - Abstract
AIMS: The burden of cardiovascular disease is increasing worldwide, which has to be reflected by cardiovascular (CV) research in Europe. CardioScape, a FP7 funded project initiated by the European Society of Cardiology (ESC), identified where CV research is performed, how it is funded and by whom. It could be transformed into an on-line and up-to-date resource of great relevance for researchers, funding bodies and policymakers and could be a role model for mapping CV research funding in Europe and beyond. METHODS AND RESULTS: Relevant funding bodies in 28 European Union (EU) countries were identified by a multistep process involving experts in each country. Projects above a funding threshold of 100 k€ during the period 2010-2012 were included using a standard questionnaire. Results were classified by experts and an adaptive text analysis software to a CV-research taxonomy, integrating existing schemes from ESC journals and congresses. An on-line query portal was set up to allow different users to interrogate the database according to their specific viewpoints. CONCLUSION: CV-research funding varies strongly between different nations with the EU providing 37% of total available project funding and clear geographical gradients exist. Data allow in depth comparison of funding for different research areas and led to a number of recommendations by the consortium. CardioScape can support CV research by aiding researchers, funding agencies and policy makers in their strategic decisions thus improving research quality if CardioScape strategy and technology becomes the basis of a continuously updated and expanded European wide publicly accessible database. ispartof: EUROPEAN HEART JOURNAL vol:39 issue:25 pages:2423-2430 ispartof: location:England status: published
- Published
- 2017
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