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Aim: This study aimed to explore the experiences of family caregivers interacting with people with dementia., Background: A majority of people with mild-to-moderate dementia live at home with family caregivers. This interaction creates positive experiences and challenges for these caregivers., Design: Descriptive phenomenological qualitative inquiry guided this study., Methods: This qualitative study involved semi-structured interviews with the caregivers of people with mild-to-moderate dementia (n = 10). Data were collected from June to September 2018, and then data were thematically analysed., Results: Six categories of themes were identified from the interviews: (1) unexpected things often happen; (2) positive coping strategies; (3) sense of accomplishment because people with dementia actively participate in activities; (4) sense of frustration because of the reluctance of people with dementia to participate in activities; (5) hope for the happiness of people with dementia; and (6) want to have their own life., Conclusions: This study reveals that caregivers could positively interact with people with dementia through creating opportunities and arranging meaningful activities. Future research should focus on family management and training on how to help caregivers interact effectively with people with dementia., (© 2020 The Authors. International Journal of Nursing Practice published by John Wiley & Sons Australia, Ltd.)