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A fluorinated and a non-fluorinated axially chiral 1,8-diarylnaphthalene ligand have been synthesized through an Ullmann and Suzuki coupling reaction based strategy. A practical methodology for the successful chiral resolution of the newly synthesized catechol based moiety is presented. We also disclose the preliminary application of these axially chiral molecules as ligands in asymmetric transformation reactions. [ABSTRACT FROM AUTHOR]

In the presence of a catalytic amount of GaCl3, dimethyl 2-(naphthalen-1-yl)cyclopropane-1,1-dicarboxylate 5 undergoes selective [3+2]-annulation-type dimerization to give a polysubstituted cyclopentane containing two naphthalenyl substituents in the vicinal position ( Scheme 2). Treatment of the same cyclopropane with an equimolar amount of GaCl3⋅THF results in dimerization with electrophilic attack on each of the benzene rings to give [3+3] and [3+4] annulation products. The latter represent a new type of dimerization of donoracceptor cyclopropanes. Finally, under conditions of double catalysis with GaCl3, 3,3,5,5-tetrasubstituted 4,5-dihydropyrazole, this cyclopropane-dicarboxylate undergoes stereospecific dimerization as a result of electrophilic ipso-attack to give a tetracyclic pentaleno[6a,1- a]naphthalene derivative ( Scheme 5). Possible reaction mechanisms are proposed. [ABSTRACT FROM AUTHOR]

The copper(I)-catalyzed domino reactions between the easily accessible 3-(2-halobenzyl)pentane-2,4-diones and β-keto esters, malonates and cyanoacetates afford trisubstituted naphthoates and naphthonitriles with yields up to 85%. [ABSTRACT FROM AUTHOR]

In the presence of PtCl2/CO catalyst, 2-alkenyl-(1′-hydroxyl-4-en-2-ynyl)benzenes undergo a tandem electrophilic 6-exo-dig cyclization-Nazarov cyclization sequence to give 1H-cyclopenta[a]naphthalenes efficiently and regioselectively. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Enaminones as Synthons for a Directed C-H Functionalization: RhIII-Catalyzed Synthesis of Naphthalenes" by S. Zhou, and others, published in the "Angewandte Chemie International Edition" in 2016.

A graphical abstract of the study "1-Naphthol Synthesis Through Base-Promoted SNAr Reactions of Ortho-Haloacetophenones Followed by Lewis-Acid-Catalyzed Cyclization" by X. Yu and colleagues is presented.

The mild one-step cycloisomerization strategy delivers complex molecular architectures in high yields which are inaccessible following conventional methods. [ABSTRACT FROM AUTHOR]

The first Pd-catalyzed C-H activation/C-OTf bond forming process is developed to provide C8 triflated 1-naphthylamides regioselectively. [ABSTRACT FROM AUTHOR]

A novel procedure for the nickel-catalyzed deoxygenation of aryl ethers in the absence of an external reductant is developed. [ABSTRACT FROM AUTHOR]

Photoinduced and Ir-catalyzed intermolecular annulation of vinyl radicals derived from monosubstituted olefins offers an interesting synthesis of dihydronaphtahlenes. [ABSTRACT FROM AUTHOR]

A novel Pt-catalyzed rearrangement reaction of biphenyls (I) is developed to form azulene derivatives by structural reorganization between the ethyne and arylethyne moieties. [ABSTRACT FROM AUTHOR]