1. Catalyst discovery through megalibraries of nanomaterials.
- Author
-
Kluender EJ, Hedrick JL, Brown KA, Rao R, Meckes B, Du JS, Moreau LM, Maruyama B, and Mirkin CA
- Subjects
- Copper chemistry, Gold Alloys chemistry, High-Throughput Screening Assays, Metal Nanoparticles chemistry, Nanotubes, Carbon chemistry, Spectrum Analysis, Raman, Catalysis, Nanostructures chemistry, Small Molecule Libraries
- Abstract
The nanomaterial landscape is so vast that a high-throughput combinatorial approach is required to understand structure-function relationships. To address this challenge, an approach for the synthesis and screening of megalibraries of unique nanoscale features (>10,000,000) with tailorable location, size, and composition has been developed. Polymer pen lithography, a parallel lithographic technique, is combined with an ink spray-coating method to create pen arrays, where each pen has a different but deliberately chosen quantity and composition of ink. With this technique, gradients of Au-Cu bimetallic nanoparticles have been synthesized and then screened for activity by in situ Raman spectroscopy with respect to single-walled carbon nanotube (SWNT) growth. Au
3 Cu, a composition not previously known to catalyze SWNT growth, has been identified as the most active composition., Competing Interests: Conflict of interest statement: K.A.B. and C.A.M. have financial interests in TERA-print, LLC, which could potentially benefit from the outcomes of this research. All other authors declare no competing interests.- Published
- 2019
- Full Text
- View/download PDF