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A synthetic route for the preparation of alkynylated saturated N‐heterocycles via a sequential combination of a Shono oxidation and a gold(I)‐catalyzed alkynylation reaction has been developed. The electrochemical Shono oxidation allowed an efficient access to a variety of N,O‐acetals via a direct C−H bond functionalization of cyclic amines. The reaction conditions were amenable with functionalized pyrrolidine, tetrahydroisoquinoline and pyrrolidine‐cyclopropyl fused bicyclic skeletons. The gold‐catalyzed process allowed the introduction of aryl acetylene partners bearing electron‐donating and moderate electron‐withdrawing. The efficiency of the gold process is remarkable and could be scaled up to 5 mmol of N,O‐acetal. Post‐functionalization reactions were performed based on the reactivity of the alkyne, showing the broad interest of our methodology. Promising preliminary results on an asymmetric version were obtained (e.r. up to 84.5:15.5). [ABSTRACT FROM AUTHOR]

Metal salts of triflic acid, CF3SO2OH and of triflimidic acid, [CF3SO2]2NH, often called 'Lewis superacids', are powerful catalysts for several classes of reactions. Typical applications developed at the Institut de Chimie de Nice during the last decade, mostly in the domain of inter- and intramolecular carbon-carbon, carbon-oxygen and carbon-sulfur bond formation, are illustrated. During the last three years, the characterization of metal triflates and triflimides by electrospray mass spectrometry was also accomplished in our Institute. Displacement of one anion of the salt by strong neutral ligands was developed as a mean for generating characteristic positive ions. In an effort toward the quantitative description of the ligand/metal bonding and the catalytic role of the Lewis acid, a ligand competition method was devised. An exploratory study attests that subtle structural effects on the donor/acceptor interaction can be evidenced using this simple mass spectrometric method. Copyright © 2012 John Wiley & Sons, Ltd. [ABSTRACT FROM AUTHOR]

A series of metallic tosylates were prepared by ultrasonic metal activation and were further used as efficient catalysts for the acylation of aromatic derivatives. [ABSTRACT FROM AUTHOR]

An abstract of the article "Catalysis of the acylation of aromatic derivatives by metallic tosylates," by V. Morizur and colleagues is presented.