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Reported herein is a palladium/norbornene-catalyzed ortho-arene acylation of aryl iodides by a Catellani-type CH functionalization. This transformation is enabled by isopropyl carbonate anhydrides, which serve as both an acyl cation equivalent and a hydride source. [ABSTRACT FROM AUTHOR]

A water-soluble cationic mononuclear copper(II) complex [Cu(II) L (H 2 O)]I 2 ( 1 , H 4 L = 5,11,17,23–tetrakis(trimethylammonium)-25,26,27,28-tetrahydroxycalix[4]arene) was employed as a catalyst in the oxidation of benzyl alcohols to benzaldehydes in water. In the presence of TEMPO and H 2 O 2 , complex 1 exhibited good catalytic activity towards primary benzyl alcohols with a less catalyst loading (0.25 mol%) and a lower temperature (60 °C). The isolated yields of the aldehydes achieved 63–98% within 12 h. [ABSTRACT FROM AUTHOR]

The blockbuster antidepressant drug duloxetine contains one stereo-center derived from chiral alcohol intermediates. The stereoselective bioreductive production of five of such intermediates could be achieved using the recombinant ketoreductase Ch KRED15, yielding the enantiopure ( S )-alcohols with >99% ee. Sequence alignment indicated that Ch KRED15 lacks the conserved G-rich motif, which was then amended by a single mutation of S12G. The resulting S12G mutant displayed significantly improved catalytic activity and protein stability. When coupled with a cofactor recycling system, the S12G mutant was able to catalyze the complete conversion of ethyl 3-oxo-3-(thiophen-2-yl)propanoate within 6 h and N -methyl-3-oxo-3-(thiophen-2-yl)propanamide within 24 h at substrate concentrations of 10 and 50 g/l, respectively, without the compromise of enantioselectivity. [ABSTRACT FROM AUTHOR]

Palladium and CO.: The title reaction proceeds in the presence of CO, thus providing a synthesis for 1,3‐oxazin‐6‐ones (see scheme; DABCO=1,4‐diazabicyclo[2.2.2]octane, DMF=N,N‐dimethylformamide). The reaction tolerates a variety of functional groups on both the aryl ring and the amide of the substrate. Initial mechanistic studies suggest the activation of the alkenyl CH bond to be a key step. [ABSTRACT FROM AUTHOR]

A novel Cu(TFA)2-catalyzed oxidative tandem cyclization/1,2-alkyl migration of readily available enamino amides for the synthesis of pyrrolin-4-ones has been developed. The reaction tolerates a wide range of functional groups and is a reliable method for the rapid synthesis of substituted pyrrolin-4-ones in high yields under mild conditions. [ABSTRACT FROM AUTHOR]

Reactions of [H4L][PF6]4with 4 equiv. of Mn(OAc)2·4H2O in the presence of air gave rise to a mononuclear Mn(iii)–superoxo complex [Mn(iii)L(O2)(H2O)](PF6)2, which contains a bowl-shaped cationic structure with a D4dsymmetry. It has an unprecedented linear end-on Mn(iii)–O2unit and exhibited good efficiency and selectivity in the catalytic oxidation of alkenes with O2plus isobutyraldehyde under mild conditions. [ABSTRACT FROM AUTHOR]

The utility of this method is demonstrated in the synthesis of zolimidine (IIIg). [ABSTRACT FROM AUTHOR]

A series of 2,4,6-trisubstituted and 2,4-disubstituted pyridines is readily prepared by Fe-catalyzed reaction of ketoximes (I) and (VI) with tertiary amines. [ABSTRACT FROM AUTHOR]

starting from ketoximes and aldoximes [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Palladium-Catalyzed Aminocarbonylation of Aryl Iodides with Amides and N-Alkyl Anilines" by L. Ran and others, published in the periodical "Chemistry: An Asian Journal" in 2014.

The method is only applicable to aryl-substituted enamides, whereas aliphatic ones do not react. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Palladium-Catalyzed Oxidative Carbonylation of the Alkenyl C-H Bonds of Enamides: Synthesis of 1,3-Oxazin-6-ones" by researcher M. Chen and others published in the journal "Angewandte Chemie International Edition" in the 2013 issue.

In contrast to monoalkylmonoarylketoxime carboxylates, dialkylketoxime carboxylates do not react under the employed conditions. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Cu(TFA)2-Catalyzed Oxidative Tandem Cyclization/1,2-Alkyl Migration of Enamino Amides for Synthesis of Pyrrolin-4-ones" by Zhi-Jing Zhang et al published in the journal "ChemInform" in 2014.

The novel and efficient title synthesis affords regioselectively Z-iodoenamides from readily available ketoximes. [ABSTRACT FROM AUTHOR]

A new strategy for the title synthesis is developed. [ABSTRACT FROM AUTHOR]

Abstract: In the absence of any additional ligands, the efficient N-arylation of nitrogen-containing heterocycles with aryl iodides catalyzed by relative low catalyst amount of Cu(OAc)2·H2O was developed. This simple catalytic system is involved in the C–N cross-coupling reaction and works for a variety of pyrazole, pyrrole, imidazole, triazole, indole, benzoimidazole, benzotriazole, carbazole, and anilines as well as aryl iodides with different electronic properties. Highly efficient copper(II)-catalyzed N-arylation protocol was established. [Copyright &y& Elsevier]

This Catellani-type C-H arylation is enabled by isopropyl carbonate anhydrides (II) and (IV), which serve as both an acyl cation and a hydride source. [ABSTRACT FROM AUTHOR]

A strategy for the selective introduction of sulfonyloxy groups into unactivated β-C-H bonds of masked alcohols is described. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Versatile Palladium(II)-Catalyzed Suzuki-Miyaura Coupling in Ethanol with a Novel, Stabilizing Ligand" by J.-J. Ning and others, published in the periodical "Tetrahedron" in 2015.

The article focuses on the research "FeCl3-Catalyzed Self-Condensation of Enamides for the Synthesis of Enamido-Substituted Nitrogen-Containing Quaternary Carbon Centers" by researcher W. Du and others published in the "European Journal of Organic Chemistry" in the 2014 issue.

Reactions of NiCl2·6H2O or Ni(ClO4)2·6H2O with 2,2′-bipyridine (2,2′-bipy), or 2-bis(diphenylphosphino)ethane (dppe) or 1,4-bis(diphenylphosphino)butane (dppb) followed by addition of [Zn(Tab)4](PF6)2 (1) resulted in the formation of one trinuclear cationic complex [(2,2′-bipy)4Ni3(μ-Tab)4]Cl0.5(PF6)5.5 (2), one mononuclear cationic complex [Ni(Tab)2(dppe)](PF6)2 (3), and one dinuclear cationic complex [Ni2(dppb)(μ-Tab)2(Tab)2](PF6)2(ClO4)2 (4). Complexes 2-4 were characterized by elemental analysis, IR, UV-vis, 1H and 31P NMR, and single-crystal X-ray diffraction. In the [(2,2′-bipy)4Ni3(μ-Tab)4]6+ hexacation of 2, the central Ni(II) atom is connected to two [Ni(2,2′-bipy)2]2+ fragments by two pairs of μ-Tab ligands, forming a linear trinuclear cationic structure. The Ni(II) center of the dication of 3 is tetrahedrally coordinated by two S atoms from two Tab ligands and two P atoms of one dppe ligand. Complex 4 has a dimeric cationic structure in which two [(Tab)Ni]2+ species are linked by a pair of μ-Tab ligands and one dppb ligand. Complexes 2-4 displayed high catalytic activity toward the cross-coupling reactions of arylboronic acids and amines to produce N-arylated amines. [ABSTRACT FROM AUTHOR]

The presented new method tolerates a wide range of functional groups starting from various (hetero)aromatic and aliphatic nitriles and several nitroolefins. [ABSTRACT FROM AUTHOR]

Abstract: The cyclotrimerization of aryl isocyanates and the cyclodimerization of alkyl isocyanates initiated by one praseodymium benzenethiolate complex [Pr(SPh)3(THF)3] were investigated. Comparative runs with [Pr(SPh)3(THF)3] and its precursor Pr[(Me3Si)2N]3 showed that the former has the advantages of a higher selectivity toward isocyanates, easy preparation, low catalyst loading, high conversion as well as mild reaction conditions. [Copyright &y& Elsevier]

Various functional groups are tolerated and only atmospheric air is used as oxidant. [ABSTRACT FROM AUTHOR]

The article presents chemical equations related to the article "Palladium-Catalyzed Carbonylation of o-Iodoanilines for Synthesis of Isatoic Anhydrides" by S. Gao and others, published in the "Journal of Organic Chemistry" in 2014.