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Hydrogenations are fundamentally and industrially important reactions that are atom economical paths to synthesize value‐added products from feedstock chemicals. The cooperative effects of two or more metal centers in multimetallic active sites is a successful strategy to activate small molecules and facilitate catalytic reactions, and this strategy has been recently applied to catalytic hydrogenation reactions. Furthermore, heterobimetallic complexes have been well‐documented to provide novel reaction pathways and improved selectivity, compared to their homo‐bimetallic and monometallic analogues. This minireview provides a historical perspective on the development of heterobimetallic catalysts for the hydrogenation of unsaturated substrates and describes recent developments in this burgeoning research area. [ABSTRACT FROM AUTHOR]

This work describes two new synthetic methods for the preparation of isoflavones following the Ni‐catalysed domino arylation reactions of the vast range of ortho‐hydroxyarylenaminones utilising aromatic bromides as well as carboxylic acids. The presented protocols tolerated significant variation of all coupling partners and enabled synthesis of isoflavone library of twenty‐three representatives. This is the first communicated precedent where the mechanic energy was utilised in the synthesis of isoflavones following the domino cyclisation mode. [ABSTRACT FROM AUTHOR]

Front Cover Picture: Mechanochemical Ni-Catalysed Arylation of ortho-Hydroxyarylenaminones: Synthesis of Isoflavones (Adv. Isoflavones, Arylation, Catalysis, Mechanochemistry, Methodology Keywords: Isoflavones; Arylation; Catalysis; Mechanochemistry; Methodology EN Isoflavones Arylation Catalysis Mechanochemistry Methodology 3439 3439 1 10/21/22 20221018 NES 221018 The front cover picture is a metaphor of mechanochemistry. [Extracted from the article]