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Start Over Author "Grein-Iankovski, Aline" Topic catalytic activity
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1. A tailored biocatalyst achieved by the rational anchoring of imidazole groups on a natural polymer: furnishing a potential artificial nuclease by sustainable materials engineering.

Author

Ferreira, José G. L., Grein-Iankovski, Aline, Oliveira, Marco A. S., Simas-Tosin, Fernanda F., Riegel-Vidotti, Izabel C., and Orth, Elisa S.

Subjects
*BIOPOLYMERS, *GUM arabic, *IMIDAZOLES, *CATALYTIC activity, *ARTIFICIAL nucleases, *DEPHOSPHORYLATION, *PLASMIDS
Abstract

Foreseeing the development of artificial enzymes by sustainable materials engineering, we rationally anchored reactive imidazole groups on gum arabic, a natural biocompatible polymer. The tailored biocatalyst GAIMZ demonstrated catalytic activity (＞105-fold) in dephosphorylation reactions with recyclable features and was effective in cleaving plasmid DNA, comprising a potential artificial nuclease. [ABSTRACT FROM AUTHOR]

Published
2015
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