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Your search keyword '"Mitsuzane K"' showing total 3 results
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3 results on '"Mitsuzane K"'

1. [Balloon-occluded arterial infusion as chemotherapy in bladder cancer--long-term results].

Author

Mitsuzane K, Kawabata M, Terada M, Nomura S, Sato M, and Yamada R

Subjects
Aged, Aged, 80 and over, Carcinoma, Transitional Cell mortality, Cisplatin administration & dosage, Doxorubicin administration & dosage, Female, Follow-Up Studies, Humans, Infusions, Intra-Arterial, Male, Mitomycin, Mitomycins administration & dosage, Prognosis, Survival Rate, Urinary Bladder Neoplasms mortality, Antineoplastic Combined Chemotherapy Protocols administration & dosage, Carcinoma, Transitional Cell therapy, Catheterization, Urinary Bladder Neoplasms therapy
Abstract

One hundred three patients with bladder cancer underwent balloon-occluded arterial infusion. In 66 patients whose therapeutic effects could be evaluated by endoscope, CT and angiography, the anti-tumor effective rate (CR + PR) was 78.8%. In 15 patients who were not treated by trans-urethral resection or total cystectomy but BOAI, one-year cumulative survival rate was 46.7% and the two-year rate 13.3%. The longest survival period after BOAI was 7 years and 8 months. 133Xe activity of bladder tumor area in BOAI was 6.60 times higher than in simple arterial infusion. BOAI was thought to be a promising conservative treatment in advanced bladder cancer.

Published
1990

2. An attempt of hyperthermia with balloon catheter and immunochemotherapeutic agent.

Author

Yamada R, Tsuji K, Kishi K, Suwa K, Mitsuzane K, Tanaka K, Satoh M, Kawabata M, and Maeda M

Subjects
Combined Modality Therapy, Humans, Infusions, Intra-Arterial, Antineoplastic Combined Chemotherapy Protocols therapeutic use, Biological Products therapeutic use, Carcinoma, Hepatocellular therapy, Catheterization, Hyperthermia, Induced methods, Liver Neoplasms therapy, Picibanil therapeutic use, Urinary Bladder Neoplasms therapy
Abstract

The following studies were performed to develop a new technique of hyperthermia by vascular catheterization for the treatment of malignant neoplasm. A balloon catheter was inserted into the artery of a cancer-affected organ and inflation of the balloon temporarily occluded the artery, after which an anticancer drug solution warmed to 45 degrees C was infused. The purpose of this technique was to enable the solution to arrive at the affected area undiluted by blood. It would then remain in the organ and act on the lesion. When OK-432 was intravenously administered to induce pyrexia of 40 degrees C, followed by the above-mentioned arterial infusion, it was expected that the effects of hyperthermia and chemotherapy would be synergistic. In cases of liver cancer and urinary bladder cancer subjected to the arterial infusion of warmed anticancer drugs, however, the temperature in the hepatic vein increased by only 0.5 degree C while that in urethra near the tumor increased by only 1 degree C. In the future, further improvement needs to be made to obtain effective local heating with this technique.

Published
1988

3. Self-expandable metallic stent therapy for superior vena cava syndrome: clinical observations

Author

Shintaro Shirai, Morio Sato, Ryusaku Yamada, Norifumi Nishida, Hisashi Kobayashi, Ren-Jie Yang, Mitsuzane K, Tetsuo Sonomura, and Kazushi Kishi

Subjects
Male, Superior Vena Cava Syndrome, medicine.medical_specialty, Vena Cava, Superior, Central Venous Pressure, medicine.medical_treatment, Blood Pressure, Atrial Function, Right, Constriction, Pathologic, Radiology, Interventional, Catheterization, Constriction, Self-expandable metallic stent, Superior vena cava, medicine, Humans, Radiology, Nuclear Medicine and imaging, cardiovascular diseases, Aged, Superior vena cava syndrome, business.industry, Central venous pressure, Stent, Equipment Design, Middle Aged, Stainless Steel, medicine.disease, Radiography, Survival Rate, Stenosis, Balloon dilation, Female, Stents, Radiology, medicine.symptom, Nuclear medicine, business, Follow-Up Studies
Abstract

PURPOSE: To study clinical and physiologic aspects of Z-stent therapy for superior vena cava (SVC) syndrome secondary to malignant disease. MATERIALS AND METHODS: Signs and symptoms of SVC syndrome were classified, graded, and scored in 11 cases. Six patients with caval pressure higher than 22 mm Hg peripheral to the stenosis underwent stent therapy. RESULTS: Immediately after Z-stent implantation into the stenotic lesion, the diameter of the constriction increased from 3.3 mm +/- 2.0 (mean +/- standard deviation) to 14.0 mm +/- 3.2, the mean caval pressure peripheral to the stenosis decreased from 26.6 mm Hg +/- 2.5 to 8.9 mm Hg +/- 0.7, and the symptom score decreased from 6.7 +/- 1.8 to 1.3 +/- 1.4. The caval pressure, lesion diameter, and symptom score correlated highly with each other. One complication--transient pulmonary edema attributable to volume overload caused by reperfusion--was observed. Mean survival exceeded 7.1 months. CONCLUSION: Stent placement could be a useful treatment for refractory...

Published
1993

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