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Start Over Author "zhu, Huiyan" Topic cell proliferation
2 results on '"zhu, Huiyan"'

1. Existence of traveling wavefronts for Sherratt’s avascular tumor model

Author

Zhu, Huiyan and Ou, Chunhua

Subjects
*TUMOR growth, *BIOLOGICAL mathematical modeling, *HOLOGRAPHY, *MATHEMATICAL continuum, *DIETARY supplements, *CELL motility, *PERTURBATION theory, *BANACH algebras, *FIXED point theory, *CELL proliferation
Abstract

Abstract: In this paper, we revisit Sherratt’s avascular tumor growth system modeled in terms of the continuum densities of proliferating, quiescent and necrotic cells, together with the consideration of the generic nutrient supply from underlying tissue and cell movement of contact inhibition. By adopting a perturbation method combined with the Banach fixed point theorem, we theoretically justify the existence of the traveling wavefronts for this model. [Copyright &y& Elsevier]

Published
2011
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2. Circular RNA profile identifies circPVT1 as a proliferative factor and prognostic marker in gastric cancer.

Author

Chen, Jie, Li, Yan, Zheng, Qiupeng, Bao, Chunyang, He, Jian, Chen, Bin, Lyu, Dongbin, Zheng, Biqiang, Xu, Yu, Long, Ziwen, Zhou, Ye, Zhu, Huiyan, Wang, Yanong, He, Xianghuo, Shi, Yingqiang, and Huang, Shenglin

Subjects
*STOMACH cancer, *BIOMARKERS, *GENE expression, *NON-coding RNA, *PROGRESSION-free survival, *CELL proliferation, *ADENOCARCINOMA, *CELL physiology, *PROGNOSIS, *RNA, *STOMACH tumors
Abstract

Circular RNAs (circRNAs) comprise a novel class of widespread non-coding RNAs that may regulate gene expression in eukaryotes. However, the characterization and function of circRNAs in human cancer remain elusive. Here we identified at least 5500 distinct circRNA candidates and a series of circRNAs that are differentially expressed in gastric cancer (GC) tissues compared with matched normal tissues. We further characterized one circRNA derived from the PVT1 gene and termed it as circPVT1. The expression of circPVT1 is often upregulated in GC tissues due to the amplification of its genomic locus. circPVT1 may promote cell proliferation by acting as a sponge for members of the miR-125 family. The level of circPVT1 was observed as an independent prognostic marker for overall survival and disease-free survival of patients with GC. Our findings suggest that circPVT1 is a novel proliferative factor and prognostic marker in GC. [ABSTRACT FROM AUTHOR]

Published
2017
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