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1. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Biochemical Markers

Author

O'Toole, D., Grossman, A., Gross, D., Fave, G. D., Barkmanova, J., O'Connor, J., Pape, U. F., Plöckinger, U., Åkerström, G., Annibale, B., Arnold, R., Bajetta, E., Chen, Y. J., Costa, F., Couvelard, A., Davar, J., Herder, W. D., Eriksson, B., Falconi, M., Ferone, D., Gustafsson, B., Hyrdel, R., Ivan, D., Kaltsas, G., Kianmanesh, R., Klöppel, G., Knigge, U. P., Komminoth, P., Kos Kudla, B., Kwekkeboom, D., Lebtahi, R., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Öberg, K., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, Aldo, Scheidhauer, K., Scoazec, J. Y., Sundin, A., Szpak, W., Taal, B., Vitek, P., Vullierme, M. P., and Wiedenmann, B.

Subjects
Endocrinology, Diabetes and Metabolism, Diagnostic accuracy, insulinoma, Neuroendocrine tumors, Bioinformatics, secretin, 0302 clinical medicine, Endocrinology, immune system diseases, cancer diagnosis, conference paper, Biochemical markers, biology, Urinary 5-hydroxyindoleacetic acid, Chromogranin A, Fasting, Hydroxyindoleacetic Acid, Diabetes and Metabolism, Neuroendocrine Tumors, priority journal, 030220 oncology & carcinogenesis, diagnostic accuracy, 5 hydroxyindoleacetic acid, neuroendocrine tumor, hormones, hormone substitutes, and hormone antagonists, Neuroendocrine tumor test, musculoskeletal diseases, medicine.medical_specialty, Standard of care, MEDLINE, 610 Medicine & health, 030209 endocrinology & metabolism, 03 medical and health sciences, Cellular and Molecular Neuroscience, Patient information, Internal medicine, gastrin, medicine, Humans, biochemistry, human, Insulinoma, Gastrinoma, gastrinoma, Endocrine and Autonomic Systems, business.industry, practice guideline, biochemical marker, chromogranin A, hypoglycemia, patient information, medicine.disease, body regions, biology.protein, 570 Life sciences, Biomarkers, business
Abstract

Biomarkers have been the mainstay in the diagnosis and follow-up of patients with neuroendocrine tumors (NETs) over the last few decades. In the beginning, secretory products from a variety of subtypes of NETs were regarded as biomarkers to follow during diagnosis and treatment: serotonin for small intestinal (SI) NETs, and gastrin and insulin for pancreatic NETs. However, it became evident that a large number of NETs were so-called nonfunctioning tumors without secreting substances that caused hormone-related symptoms. Therefore, it was necessary to develop so-called “general tumor markers.” The most important ones so far have been chromogranin A and neuron-specific enolase (NSE). Chromogranin A is the most important general biomarker for most NETs with a sensitivity and specificity somewhere between 60 and 90%. NSE has been a relevant biomarker for patients with high-grade tumors, particularly lung and gastrointestinal tract tumors. Serotonin and the breakdown product urinary 5-hydroxyindoleacetic acid (U-5-HIAA) is still an important marker for diagnosing and follow-up of SI NETs. Recently, 5-HIAA in plasma has been analyzed by high-performance liquid chromatography and fluorometric detection and has shown good agreement with U-5-HIAA analysis. In the future, we will see new tests including circulating tumor cells, circulating DNA and mRNA. Recently, a NET test has been developed analyzing gene transcripts in circulating blood. Preliminary data indicate high sensitivity and specificity for NETs. However, its precise role has to be validated in prospective randomized controlled trials which are ongoing right now.

Published
2017
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2. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Radiological Examinations

Author

A. Sundin, M. Vullierme, G. Kaltsas, U. Plöckinger, Akerström G, Annibale B, Arnold R, Bajetta E, Barkmanova J, Chen YJ, Costa F, Couvelard A, Davar J, de Herder W, Delle G, Eriksson B, Ferone D, Gross D, Grossman A, Gustafsson B, Hyrdel R, Ivan D, Kianmanesh R, Klöppel G, Knigge UP, Komminoth P, Kos Kudła B, Kwekkeboom D, Lebtahi R, Lewington V, McNicol AM, Mitry E, Nilsson O, Oberg K, O'Connor J, O'Toole D, Pape UF, Papotti M, Pavel M, Perren A, Platania M, Rindi G, Ruszniewski P, Salazar R, Scarpa A, Scheidhauer K, Scoazec JY, Szpak W, Taal B, Vitek P, Wiedenmann B., FALCONI , MASSIMO, A., Sundin, M., Vullierme, G., Kaltsa, U., Plöckinger, Akerström, G, Annibale, B, Arnold, R, Bajetta, E, Barkmanova, J, Chen, Yj, Costa, F, Couvelard, A, Davar, J, de Herder, W, Delle, G, Eriksson, B, Falconi, Massimo, Ferone, D, Gross, D, Grossman, A, Gustafsson, B, Hyrdel, R, Ivan, D, Kianmanesh, R, Klöppel, G, Knigge, Up, Komminoth, P, Kos Kudła, B, Kwekkeboom, D, Lebtahi, R, Lewington, V, Mcnicol, Am, Mitry, E, Nilsson, O, Oberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Papotti, M, Pavel, M, Perren, A, Platania, M, Rindi, G, Ruszniewski, P, Salazar, R, Scarpa, A, Scheidhauer, K, Scoazec, Jy, Szpak, W, Taal, B, Vitek, P, and Wiedenmann, B.

Subjects
medicine.medical_specialty, radiodiagnosis, diagnostic imaging, Endocrinology, Diabetes and Metabolism, multidetector computed tomography, Diagnostic accuracy, Neuroendocrine tumors, cancer diagnosis, computer assisted tomography, conference paper, diagnostic accuracy, echography, human, medical documentation, medical society, neuroendocrine tumor, nuclear magnetic resonance imaging, patient information, practice guideline, priority journal, radiation dose, sensitivity and specificity, Cellular and Molecular Neuroscience, Endocrinology, X ray computed, Internal medicine, Multidetector computed tomography, medicine, Humans, Ultrasonography, Endocrine and Autonomic Systems, business.industry, General surgery, Radiation dose, medicine.disease, Magnetic Resonance Imaging, Medical documents, Neuroendocrine Tumors, Radiological weapon, Radiology, Tomography, X-Ray Computed, business
Abstract

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : Radiological Examinations

Published
2008
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3. Rare functioning pancreatic endocrine tumors

Author

O'Toole D, Salazar R, Kaltsas G, Couvelard A, De Herder WW, Hyrdel R, Nikou G, Krenning E, Vullierme MP, Caplin M, Jensen R, Eriksson B, Ahlman H, Arnold R, Bechstein WO, Cadiot G, Christ E, Chung D, Delle Fave G, Falchetti A, Ferone D, Goretzki P, Gross D, Hochhauser D, Keleştimur F, Kianmanesh R, Knapp W, Knigge UP, Komminoth P, Körner M, Kos Kudła B, Kvols L, Kwekkeboom DJ, Lewington V, Lopes JM, Manfredi R, McNicol AM, Mitry E, Niederle B, Nilsson O, Öberg K, O'Connor J, Pauwels S, Pape UF, Pavel M, Perren A, Plöckinger U, Ramage J, Ricke J, Rindi G, Ruszniewski P, Sauvanet A, Scarpa A, Scoazec JY, Sevilla Garcia MI, Steinmüller T, Sundin A, Taal B, Van Cutsem E, Wiedenmann B, Wildi S, Yao JC, Zgliczynski S., FALCONI , MASSIMO, Internal Medicine, Radiology & Nuclear Medicine, O'Toole, D, Salazar, R, Falconi, Massimo, Kaltsas, G, Couvelard, A, De Herder, Ww, Hyrdel, R, Nikou, G, Krenning, E, Vullierme, Mp, Caplin, M, Jensen, R, Eriksson, B, Ahlman, H, Arnold, R, Bechstein, Wo, Cadiot, G, Christ, E, Chung, D, Delle Fave, G, Falchetti, A, Ferone, D, Goretzki, P, Gross, D, Hochhauser, D, Keleştimur, F, Kianmanesh, R, Knapp, W, Knigge, Up, Komminoth, P, Körner, M, Kos Kudła, B, Kvols, L, Kwekkeboom, Dj, Lewington, V, Lopes, Jm, Manfredi, R, Mcnicol, Am, Mitry, E, Niederle, B, Nilsson, O, Öberg, K, O'Connor, J, Pauwels, S, Pape, Uf, Pavel, M, Perren, A, Plöckinger, U, Ramage, J, Ricke, J, Rindi, G, Ruszniewski, P, Sauvanet, A, Scarpa, A, Scoazec, Jy, Sevilla Garcia, Mi, Steinmüller, T, Sundin, A, Taal, B, Van Cutsem, E, Wiedenmann, B, Wildi, S, Yao, Jc, and Zgliczynski, S.

Subjects
medicine.medical_specialty, Endocrine and Autonomic Systems, Endocrinology, Diabetes and Metabolism, Humans, Neuroendocrine Tumors, Pancreatic Neoplasms, Biology, University hospital, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, medicine
Abstract

a Department of Gastroenterology, Beaujon Hospital, Clichy , France; b Department of Oncology, Institut Catala d’Oncologia, Barcelona , Spain; c Department of Surgery, Verona University, Verona , Italy; d Department of Endocrinology and Metabolism, Genimatas Hospital, Athens , Greece; e Department of Gastroenterology, Beaujon Hospital, Clichy , France; f Department of Endocrinology, Erasmus MC University, Rotterdam , The Netherlands; g Department of Internal Medicine, Martin University, Martin , Slovakia; h Department of Propaedeutic Internal Medicine, Laiko Hospital, Athens , Greece; i Department of Nuclear Medicine, Erasmus MC University, Rotterdam , The Netherlands; j Department of Gastroenterology, Beaujon Hospital, Clichy , France; k Department of Gastroenterology, Royal Free Hospital, London , UK; l Department of Cell Biology, National Institute of Health, Bethesda, Md. , USA; m Department of Endocrinology, University Hospital, Uppsala , Sweden

Published
2006

4. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors:Echocardiography

Author

Plöckinger, U., Gustafsson, B., Ivan, D., Szpak, W., Davar, J., Åkerstrom, G., Annibale, B., Arnold, R., Bajetta, E., Barkmanova, J., Chen, Y. J., Costa, F., Couvelard, A., Herder, W. D., Fave, G. D., Eriksson, B., Falconi, M., Ferone, D., Gross, D., Grossman, A., Hyrdel, R., Kaltsas, G., Kianmanesh, R., Klöppel, G., Knigge, U. P., Komminoth, P., Kos Kudla, B., Kwekkeboom, D., Lebtahi, R., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Öberg, K., O'Connor, J., O'Toole, D., Pape, U. F., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, Aldo, Scheidhauer, K., Scoazec, J. Y., Sundin, A., Taal, B., Vitek, P., Vullierme, M. P., and Wiedenmann, B.

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Carcinoid tumors, MEDLINE, Carcinoid Heart Disease, carcinoid syndrome, Diagnostic accuracy, Disease, Neuroendocrine tumors, Cellular and Molecular Neuroscience, Endocrinology, cancer diagnosis, Internal medicine, Humans, echocardiography, Medicine, human, medical society, conference paper, medical documentation, Endocrine and Autonomic Systems, business.industry, practice guideline, Medical practice, diagnostic accuracy, medical practice, neuroendocrine tumor, patient information, priority journal, medicine.disease, Medical documents, Neuroendocrine Tumors, business, Carcinoid syndrome
Abstract

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : echocardiography.

Published
2009
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5. Consensus guidelines for the management of patients with liver metastases from digestive (neuro) endocrine tumors: Foregut, midgut, hindgut, and unknown primary

Author

Steinmüller, T., Kianmanesh, R., Falconi, Massimo, Scarpa, Aldo, Taal, B., Kwekkeboom, D., Lopes, J., Perren, A., Nikou, G., Yao, J., Fave, G. D., O'Toole, D., Ahlman, H., Arnold, R., Auernhammer, C., Caplin, M., Christ, E., Couvelard, A., Herder, W. D., Eriksson, B., Ferone, D., Goretzki, P., Gross, D., Hyrdel, R., Jensen, R., Kaltsas, G., Keleştimur, F., Klöppel, G., Knapp, W., Knigge, U., Komminoth, P., Körner, M., Kos Kudła, B., Krenning, E., Kulke, M., Kvols, L., Manfredi, Riccardo, Mcnicol, A., Niederle, B., Nilsson, O., Öberg, K., O'Connor, J., Pape, U., Pavel, M., Plöckinger, U., Ramage, J., Ricke, J., Rindi, G., Ruszniewski, P., Salazar, R., Scoazec, J., Garcia, M. S., Sundin, A., Vullierme, M., Wiedenmann, B., Wildi, S., Thomas, Steinmüller, Reza, Kianmanesh, Falconi, Massimo, Aldo, Scarpa, Babs, Taal, Dik J., Kwekkeboom, José M., Lope, Aurel, Perren, George, Nikou, James, Yao, Gian Franco, Delle, Dermot, O'Toole, Frascati Consensus, Conference, Radiology & Nuclear Medicine, and Cardiology

Subjects
medicine.medical_specialty, Consensus, ACTING SOMATOSTATIN ANALOG, Endocrinology, Diabetes and Metabolism, Guidelines as Topic, Biology, HEPATIC ARTERIAL CHEMOEMBOLIZATION, Metastasis, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, Endocrine Gland Neoplasms, medicine, Digestive System, Humans, Liver Neoplasms, Endocrine system, Endocrine gland neoplasm, Endocrine and Autonomic Systems, General surgery, Cancer, Hindgut, Midgut, Foregut, LASER-INDUCED THERMOTHERAPY, medicine.disease, HEPATIC ARTERIAL CHEMOEMBOLIZATION, GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS, LASER-INDUCED THERMOTHERAPY, ACTING SOMATOSTATIN ANALOG, PORTAL-VEIN EMBOLIZATION, ISLET-CELL CARCINOMA, ISLET-CELL CARCINOMA, PORTAL-VEIN EMBOLIZATION, Unknown primary, GASTROENTEROPANCREATIC NEUROENDOCRINE TUMORS
Abstract

a DRK Kliniken Westend, Berlin , Germany; b UFR Bichat-Beaujon-Louis Mourier, Service de Chirurgie Digestive, Hopital Louis Mourier, Colombes , France; c Medicine and Surgery, General Surgery Section, MED/18 – General Surgery and d Department of Pathology, University of Verona, Verona , Italy; e Netherlands Cancer Centre, Amsterdam , and f Department of Nuclear Medicine, Erasmus University Medical Center, Rotterdam , The Netherlands

Published
2008

6. Consensus guidelines for the management of patients with digestive neuroendocrine tumors - Well-differentiated jejunal-ileal tumor/carcinoma

Author

Eriksson, B., Klöppel, G., Krenning, E., Ahlman, H., Plöckinger, U., Wiedenmann, B., Arnold, R., Auernhammer, C., Körner, M., Rindi, G., Wildi, S., Caplin, M., Fave, G. D., Ferone, D., Goretzki, P., Hyrdel, R., Jensen, R., Kaltsas, G., Keleştimur, F., Kianmanesh, R., Komminoth, P., Kos Kudła, B., Kvols, L., Kwekkeboom, D., Lopes, J., Manfredi, Riccardo, Mcnicol, A., Niederle, B., Nilsson, O., Nikou, G., Öberg, K., O'Connor, J., O'Toole, D., Pavel, M., Perren, A., Ramage, J., Ricke, J., Ruszniewski, P., Scarpa, Aldo, Scoazec, J., Garcia, M. S., Steinmüller, T., Taal, B., Vullierme, M., Yao, J., and Radiology & Nuclear Medicine

Subjects
medicine.medical_specialty, Pathology, Consensus, MIDGUT CARCINOID-TUMORS, ENDOCRINE GASTROENTEROPANCREATIC TUMORS, RECEPTOR-MEDIATED RADIOTHERAPY, RADIOLABELED SOMATOSTATIN ANALOG, RECOMBINANT INTERFERON-ALPHA, RADIONUCLIDE THERAPY, MIDGUT CARCINOID-TUMORS, Endocrinology, Diabetes and Metabolism, RADIONUCLIDE THERAPY, Neuroendocrine tumors, digestive system, RECOMBINANT INTERFERON-ALPHA, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, Carcinoma, Humans, Medicine, ENDOCRINE GASTROENTEROPANCREATIC TUMORS, Gastrointestinal Neuroendocrine Tumor, RADIOLABELED SOMATOSTATIN ANALOG, Jejunal Neoplasms, Endocrine and Autonomic Systems, business.industry, digestive, oral, and skin physiology, Metastatic carcinoid tumor, Cancer, medicine.disease, Carcinoma, Neuroendocrine, Well differentiated, Ileal Neoplasms, Practice Guidelines as Topic, Radionuclide therapy, Neuroendocrine therapy, business, RECEPTOR-MEDIATED RADIOTHERAPY
Abstract

Consensus guidelines for the management of patients with digestive neuroendocrine tumors : well-differentiated jejunal-ileal tumor/carcinoma

Published
2008
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7. Poorly differentiated carcinomas of the foregut (gastric, duodenal and pancreatic)

Author

Nilsson, O., Cutsem, E. V., Fave, G. D., Yao, J., Pavel, M., Mcnicol, A., Garcia, M. S., Knapp, W., Keleştimur, F., Sauvanet, A., Pauwels, S., Kwekkeboom, D., Caplin, M., Ahlman, H., Arnold, R., Bechstein, W., Cadiot, G., Christ, E., Chung, D., Couvelard, A., Herder, W. D., Eriksson, B., Falchetti, A., Falconi, Massimo, Ferone, D., Goretzki, P., Gross, D., Hochhauser, D., Hyrdel, R., Jensen, R., Kaltsas, G., Kianmanesh, R., Knigge, U., Komminoth, P., Körner, M., Kos Kudła, B., Kvols, L., Lewington, V., Lopes, J., Manfredi, Riccardo, Mitry, E., Niederle, B., Nikou, G., Öberg, K., O'Connor, J., O'Toole, D., Pape, U., Perren, A., Plöckinger, U., Ramage, J., Ricke, J., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, Aldo, Scoazec, J., Steinmüller, T., Sundin, A., Taal, B., Vullierme, M., Wiedenmann, B., Wildi, S., Zgliczynski, S., Radiology & Nuclear Medicine, O., Nilsson, E. V., Cutsem, G. D., Fave, J., Yao, M., Pavel, A., Mcnicol, M. S., Garcia, W., Knapp, F., Keleştimur, A., Sauvanet, S., Pauwel, D., Kwekkeboom, M., Caplin, and Falconi, M

Subjects
SMALL-CELL-CARCINOMA, NEUROENDOCRINE CARCINOMAS, TUMORS, CHEMOTHERAPY, STOMACH, MANAGEMENT, CISPLATIN, ETOPOSIDE, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Biology, Cellular and Molecular Neuroscience, CISPLATIN, Endocrinology, Duodenal Neoplasms, Stomach Neoplasms, Internal medicine, STOMACH, SMALL-CELL-CARCINOMA, medicine, MANAGEMENT, Humans, ddc:610, Royal infirmary, Endocrine and Autonomic Systems, Poorly differentiated, General surgery, GASTRIC/DUODENAL, Carcinoma, CHEMOTHERAPY, TUMORS, Neuroendocrine Carcinomas, Pancreatic Neoplasms, ETOPOSIDE, NEUROENDOCRINE CARCINOMAS
Abstract

a Department of Pathology, Gothenburg University, Gothenburg , Sweden; b Department of Gastroenterology, Gasthuisberg University, Leuven , Belgium; c Department of Gastroenterology, Ospedale S. Andrea, Rome , Italy; d Department of Oncology, University of Texas, Houston, Tex. , USA; e Department of Endocrinology, Erlangen University, Erlangen , Germany; f Department of Oncology and Pathology, Royal Infirmary Hospital, Glasgow , UK; g Department of Oncology, Virgen de la Victoria Hospital, Malaga , Spain; h Department of Nuclear Medicine, Medizinische Hochschule Hannover, Hannover , Germany; i Department of Endocrinology, Erciyes University, Kayseri , Turkey; j Department of Surgery, Beaujon Hospital, Clichy , France; k Department of Nuclear Medicine, Catholique de Louvain University, Brussels , Belgium; l Department of Nuclear Medicine, Erasmus MC University, Rotterdam , The Netherlands; m Department of Gastroenterology, Royal Free Hospital, London , UK

Published
2006

8. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Towards a Standardized Approach to the Diagnosis of Gastroenteropancreatic Neuroendocrine Tumors and Their Prognostic Stratification

Author

Klöppel, G., Couvelard, A., Perren, A., Komminoth, P., Mcnicol, A., Nilsson, O., Scarpa, Aldo, Scoazec, J., Wiedenmann, B., Papotti, M., Rindi, G., Plöckinger, U., Akerström, G, Annibale, B, Arnold, R, Bajetta, E, Barkmanova, J, Chen, Yj, Costa, F, Davar, J, de Herder, W, Delle Fave, G, Eriksson, B, Falconi, Massimo, Ferone, D, Gross, D, Grossman, A, Gustafsson, B, Hyrdel, R, Ivan, D, Kaltsas, G, Kianmanesh, R, Knigge, Up, Kos Kudła, B, Kwekkeboom, D, Lebtahi, R, Lewington, V, Mitry, E, Oberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Pavel, M, Perren, A, Platania, M, Rindi, G, Ruszniewski, P, Salazar, R, Scheidhauer, K, Sundin, A, Szpak, W, Taal, B, Vitek, P, Vullierme, M. P., G., Klöppel, A., Couvelard, A., Perren, P., Komminoth, A., Mcnicol, O., Nilsson, A., Scarpa, J., Scoazec, B., Wiedenmann, M., Papotti, G., Rindi, U., Plöckinger, Akerström, G, Annibale, B, Arnold, R, Bajetta, E, Barkmanova, J, Chen, Yj, Costa, F, Davar, J, de Herder, W, Delle Fave, G, Eriksson, B, Falconi, Massimo, Ferone, D, Gross, D, Grossman, A, Gustafsson, B, Hyrdel, R, Ivan, D, Kaltsas, G, Kianmanesh, R, Knigge, Up, Kos Kudła, B, Kwekkeboom, D, Lebtahi, R, Lewington, V, Mitry, E, Oberg, K, O'Connor, J, O'Toole, D, Pape, Uf, Pavel, M, Perren, A, Platania, M, Rindi, G, Ruszniewski, P, Salazar, R, Scheidhauer, K, Sundin, A, Szpak, W, Taal, B, Vitek, P, and Vullierme, M. P.

Subjects
Oncology, Lymphatic metastasis, medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, 610 Medicine & health, Adenocarcinoma, Neuroendocrine tumors, Prognostic stratification, Cellular and Molecular Neuroscience, Endocrinology, Stomach Neoplasms, Internal medicine, medicine, Humans, Neoplasm Staging, Endocrine and Autonomic Systems, business.industry, Standardized approach, Disease classification, Biological Markers, Lymphatic Metastasis, Neuroendocrine Tumors, Pancreatic Neoplasms, Prognosis, medicine.disease, ddc, Cancer registry, 570 Life sciences, biology, Neoplasm staging, business, Biomarkers
Abstract

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : towards a standardized approach to the diagnosis of gastroenteropancreatic neuroendocrine tumors and their prognostic stratification

Published
2009
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9. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: chemotherapy in patients with neuroendocrine tumors

Author

B. Eriksson, B. Annibale, E. Bajetta, E. Mitry, M. Pavel, M. Platania, R. Salazar, U. Plöckinger, Akerström G, Arnold R, Barkmanova J, Chen YJ, Costa F, Couvelard A, Davar J, de Herder W, Delle Fave G, Ferone D, Gross D, Grossman A, Gustafsson B, Hyrdel R, Ivan D, Kaltsas G, Kianmanesh R, Klöppel G, Knigge UP, Komminoth P, Kos Kudła B, Kwekkeboom D, Lebtahi R, Lewington V, McNicol AM, Nilsson O, Oberg K, OConnor J, OToole D, Pape UF, Papotti M, Perren A, Rindi G, Ruszniewski P, Scarpa A, Scheidhauer K, Scoazec JY, Sundin A, Szpak W, Taal B, Vitek P, Vullierme MP, Wiedenmann B., FALCONI , MASSIMO, B., Eriksson, B., Annibale, E., Bajetta, E., Mitry, M., Pavel, M., Platania, R., Salazar, U., Plöckinger, Akerström, G, Arnold, R, Barkmanova, J, Chen, Yj, Costa, F, Couvelard, A, Davar, J, de Herder, W, Delle Fave, G, Falconi, Massimo, Ferone, D, Gross, D, Grossman, A, Gustafsson, B, Hyrdel, R, Ivan, D, Kaltsas, G, Kianmanesh, R, Klöppel, G, Knigge, Up, Komminoth, P, Kos Kudła, B, Kwekkeboom, D, Lebtahi, R, Lewington, V, Mcnicol, Am, Nilsson, O, Oberg, K, Oconnor, J, Otoole, D, Pape, Uf, Papotti, M, Perren, A, Rindi, G, Ruszniewski, P, Scarpa, A, Scheidhauer, K, Scoazec, Jy, Sundin, A, Szpak, W, Taal, B, Vitek, P, Vullierme, Mp, and Wiedenmann, B.

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, medicine.medical_treatment, Dacarbazine, Antineoplastic Agents, Neuroendocrine tumors, Capecitabine, Cellular and Molecular Neuroscience, Endocrinology, Internal medicine, Antineoplastic Combined Chemotherapy Protocols, Medicine, Humans, In patient, Chemotherapy, Temozolomide, Endocrine and Autonomic Systems, business.industry, Imatinib, medicine.disease, Oxaliplatin, Neuroendocrine Tumors, business, medicine.drug
Abstract

ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors : Chemotherapy in Patients with Neuroendocrine Tumors

Published
2009

10. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: Peptide Receptor Radionuclide Therapy with Radiolabeled Somatostatin Analogs

Author

Kwekkeboom, D. J., Krenning, E. P., Lebtahi, R., Komminoth, P., Kos-Kudla, B., De Herder, W. W., Plockinger, U., Akerstrom, G., Annibale, B., Arnold, R., Bajetta, E., Barkmanova, J., Chen, Y. -J., Costa, F., Couvelard, A., Davar, J., Delle Fave, G., Eriksson, B., Falconi, M., Ferone, D., Gross, D., Grossman, A., Gustafsson, B., Hyrdel, R., Ivan, D., Kaltsas, G., Kianmanesh, R., Kloppel, G., Knigge, U. -P., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Oberg, K., O'Connor, J., O'Toole, D., Pape, U. -F., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Ruszniewski, P., Salazar, R., Scarpa, A., Scheidhauer, K., Scoazec, J. -Y., Sundin, A., Szpak, W., Taal, B., Vitek, P., Vullierme, M. -P., Wiedenmann, B., Radiology & Nuclear Medicine, and Internal Medicine

Subjects
Peptide receptor, Endocrinology, Diabetes and Metabolism, Treatment outcome, 1 4 7 10 tetraacetic acid, Neuroendocrine tumors, Endocrinology, Receptors, comparative study, conference paper, peptide receptor radionuclide therapy, 1 4 7 10 tetraazacyclododecane, GEPNET, Carcinoids, clinical trial, yttrium 90, peptide, unclassified drug, drug dose comparison, Somatostatin, priority journal, neuroendocrine tumor, medicine.medical_specialty, Receptors, Peptide, Radiolabeled somatostatin analogues, lutetium 177, octreother, octreotide[3 tyrosine], pentetreotide in 111, radioisotope, somatostatin derivative, cancer radiotherapy, drug dose escalation, human, multiple cycle treatment, practice guideline, treatment duration, treatment outcome, Cellular and Molecular Neuroscience, Internal medicine, medicine, Humans, Radioisotopes, Radiotherapy, Endocrine and Autonomic Systems, business.industry, Guideline, Neuroendocrine Tumors, medicine.disease, Clinical trial, Cancer Radiotherapy, Radionuclide therapy, business
Abstract

The purpose of this guideline is to assist physicians caring for patients with neuroendocrine tumors in considering eligibility criteria for peptide receptor radionuclide therapy (PRRT), and in defining the minimum requirements for PRRT. This guideline also makes recommendations on what minimal patient, tumor, and treatment outcome characteristics should be reported for PRRT in order to make comparisons between studies possible. It is not this guideline's aim to give specific recommendations on the use of specific radiolabeled somatostatin analogs for PRRT because different analogs are being used, and their availability depends on national law and local permissions. Copyright (C) 2009 S. Karger AG, Basel

Published
2009

11. ENETS Consensus Guidelines for the Standards of Care in Neuroendocrine Tumors: pre- and perioperative therapy in patients with neuroendocrine tumors

Author

Akerström, G., Falconi, M., Kianmanesh, R., Ruszniewski, P., Plöckinger, U., Annibale, B., Arnold, R., Bajetta, E., Barkmanova, J., Chen, Y. J., Costa, F., Couvelard, A., Davar, J., Herder, W. D., Fave, G. D., Eriksson, B., Ferone, D., Gross, D., Grossman, A., Gustafsson, B., Hyrdel, R., Ivan, D., Kaltsas, G., Klöppel, G., Knigge, U. P., Komminoth, P., Kos Kudla, B., Kwekkeboom, D., Lebtahi, R., Lewington, V., Mcnicol, A. M., Mitry, E., Nilsson, O., Öberg, K., O'Connor, J., O'Toole, D., Pape, U. F., Papotti, M., Pavel, M., Perren, A., Platania, M., Rindi, G., Salazar, R., Scarpa, Aldo, Scheidhauer, K., Scoazec, J. Y., Sundin, A., Szpak, W., Taal, B., Vitek, P., Vullierme, M. P., Wiedenmann, B., G., Akerström, Falconi, Massimo, R., Kianmanesh, P., Ruszniewski, U., Plöckinger, and Mallorca Consensus Conference, Participants

Subjects
glucagonoma, Endocrinology, Diabetes and Metabolism, perioperative period, carcinoid syndrome, Haemophilus infection, somatostatin derivative, anesthesia, insulinoma, Small, Cellular and Molecular Neuroscience, Endocrinology, Stomach Neoplasms, cancer diagnosis, Intestinal Neoplasms, Intestine, Small, Preoperative Care, Humans, electrolyte disturbance, Intestine, Neuroendocrine Tumors, Pancreas, Pancreatic Neoplasms, Postoperative Care, Stomach, human, conference paper, vipoma, gastrinoma, Endocrine and Autonomic Systems, practice guideline, diazoxide, Pneumococcus vaccine, preoperative evaluation, hypoglycemia, priority journal, octreotide, neuroendocrine tumor, preoperative care
Published
2009

12. Well-differenitated duodenal tumor/carcinoma(excluding gastrinomas)

Author

Jensen, R., Rindi, G., Arnold, R., Lopes, J., Brandi, M., Bechstein, W., Christ, E., Taal, B., Knigge, U., Ahlman, H., Kwekkeboom, D., O'Toole, D., Cadiot, G., Caplin, M., Chung, D., Couvelard, A., Herder, W. D., Fave, G. D., Eriksson, B., Falchetti, A., Falconi, Massimo, Ferone, D., Goretzki, P., Gross, D., Hochhauser, D., Hyrdel, R., Kaltsas, G., Keleştimur, F., Kianmanesh, R., Knapp, W., Komminoth, P., Körner, M., Kos Kudła, B., Kvols, L., Lewington, V., Manfredi, Riccardo, Mcnicol, A., Mitry, E., Niederle, B., Nikou, G., Nilsson, O., Öberg, K., O'Connor, J., Pauwels, S., Pape, U., Pavel, M., Perren, A., Plöckinger, U., Ramage, J., Ricke, J., Ruszniewski, P., Salazar, R., Sauvanet, A., Scarpa, Aldo, Scoazec, J., Garcia, M. S., Steinmüller, T., Sundin, A., Cutsem, E. V., Vullierme, M., Wiedenmann, B., Wildi, S., Yao, J., Zgliczynski, S., Radiology & Nuclear Medicine, R., Jensen, G., Rindi, R., Arnold, J., Lope, M., Brandi, W., Bechstein, E., Christ, B., Taal, U., Knigge, H., Ahlman, D., Kwekkeboom, D., O'Toole, G., Cadiot, M., Caplin, D., Chung, A., Couvelard, W. D., Herder, G. D., Fave, B., Eriksson, A., Falchetti, Falconi, Massimo, D., Ferone, P., Goretzki, D., Gro, D., Hochhauser, R., Hyrdel, G., Kaltsa, F., Keleştimur, R., Kianmanesh, W., Knapp, P., Komminoth, M., Körner, B., Kos Kudła, L., Kvol, V., Lewington, R., Manfredi, A., Mcnicol, E., Mitry, B., Niederle, G., Nikou, O., Nilsson, K., Öberg, J., O'Connor, S., Pauwel, U., Pape, M., Pavel, A., Perren, U., Plöckinger, J., Ramage, J., Ricke, P., Ruszniewski, R., Salazar, A., Sauvanet, A., Scarpa, J., Scoazec, M. S., Garcia, T., Steinmüller, A., Sundin, E. V., Cutsem, M., Vullierme, B., Wiedenmann, S., Wildi, J., Yao, and S., Zgliczynski

Subjects
ENDOCRINE GASTROENTEROPANCREATIC TUMORS, medicine.medical_specialty, Somatostatin receptor scintigraphy, Endocrine and Autonomic Systems, business.industry, Endocrinology, Diabetes and Metabolism, General surgery, Carcinoma, ZOLLINGER-ELLISON-SYNDROME, Well differentiated, Cellular and Molecular Neuroscience, Endocrinology, Duodenal Neoplasms, Internal medicine, Duodenal Tumor, Cancer centre, medicine, AMPULLARY CARCINOID-TUMORS, Humans, ZOLLINGER-ELLISON-SYNDROME, SOMATOSTATIN RECEPTOR SCINTIGRAPHY, ENDOCRINE GASTROENTEROPANCREATIC TUMORS, AMPULLARY CARCINOID-TUMORS, business, SOMATOSTATIN RECEPTOR SCINTIGRAPHY
Abstract

a Digestive Diseases Branch, NIDDK, NIH, Bethesda, Md. , USA; b Dipartimento di Patologia e Medicina di Laboratorio, Universita di Parma, Parma , Italy; c Division of Gastroenterology and Endocrinology, Department of Internal Medicine, Philipps University, Marburg , Germany; d Department of Pathology, IPATIMUP Hospital, Porto , Portugal; e Dipartimento di Fisiopatologia Clinica, Universita di Firenze, Firenze , Italy; f Department of Surgery, Johann-Wolfgang-Goethe-Universitat, Frankfurt , Germany; g E. Christ, Department of Endocrinology, Inselspital, Bern , Switzerland; h Department of Oncology, Netherlands Cancer Centre, Amsterdam , The Netherlands; i Department of Surgery, Rigshospitalet Blegdamsvej Hospital, Copenhagen , Denmark; j Department of Surgery, Gothenburg University, Gothenburg , Sweden; k Department of Nuclear Medicine, Erasmus Medical Center, Rotterdam , The Netherlands; l Service de Gastroenterologie-Pancreatologie, Pole des Maladies de l’Appareil Digestif, Hopital Beaujon, Clichy , France

Published
2006

13. Well-differentiated pancreatic tumor/carcinoma: Insulinoma

Author

Herder, W. D., Niederle, B., Scoazec, J., Pauwels, S., Klöppel, G., Falconi, Massimo, Kwekkeboom, D., Öberg, K., Eriksson, B., Wiedenmann, B., Rindi, G., O'Toole, D., Ferone, D., Ahlman, H., Arnold, R., Bechstein, W., Cadiot, G., Caplin, M., Christ, E., Chung, D., Couvelard, A., Fave, G. D., Falchetti, A., Goretzki, P., Gross, D., Hochhauser, D., Hyrdel, R., Jensen, R., Kaltsas, G., Keleştimur, F., Kianmanesh, R., Knapp, W., Knigge, U., Komminoth, P., Körner, M., Kos Kudła, B., Kvols, L., Lewington, V., Lopes, J., Manfredi, Riccardo, Mcnicol, A., Mitry, E., Nikou, G., Nilsson, O., O'Connor, J., Pape, U., Pavel, M., Perren, A., Plöckinger, U., Ramage, J., Ricke, J., Ruszniewski, P., Salazar, R., Sauvanet, A., Scarpa, Aldo, Garcia, M. S., Steinmüller, T., Sundin, A., Taal, B., Cutsem, E. V., Vullierme, M., Wildi, S., Yao, J., Zgliczyñski, S., W. W., de Herder, B., Niederle, J., Scoazec, S., Pauwel, G., Kloppel, Falconi, Massimo, D. J., Kwekkeboom, K., Oberg, B., Eriksson, B., Wiedenmann, G., Rindi, D., O'Toole, D., Ferone, F. C., Conference, E. N., Tumor Society, Internal Medicine, and Gastroenterology & Hepatology

Subjects
medicine.medical_specialty, Endocrinology, Diabetes and Metabolism, Intraoperative ultrasound, Carcinoma pancreas, Cellular and Molecular Neuroscience, Endocrinology, OCTREOTIDE, Internal medicine, medicine, ENDOSCOPIC ULTRASOUND, Humans, Carcinoma, Insulinoma, Pancreatic Neoplasms, Pancreas Carcinoma, Somatostatin receptor scintigraphy, SLET-CELL TUMORS, Endocrine and Autonomic Systems, business.industry, General surgery, HYPERINSULINEMIC HYPOGLYCEMIA, LOCALIZATION, University hospital, Well differentiated, SLET-CELL TUMORS, SOMATOSTATIN RECEPTOR SCINTIGRAPHY, NEUROENDOCRINE TUMORS, HYPERINSULINEMIC HYPOGLYCEMIA, INTRAOPERATIVE ULTRASOUND, ENDOSCOPIC ULTRASOUND, ENDOCRINE TUMORS, LOCALIZATION, OCTREOTIDE, MRI, ENDOCRINE TUMORS, INTRAOPERATIVE ULTRASOUND, business, SOMATOSTATIN RECEPTOR SCINTIGRAPHY, NEUROENDOCRINE TUMORS, MRI
Abstract

a Department of Internal Medicine, Section of Endocrinology, Erasmus MC, Rotterdam, The Netherlands; b Division of General Surgery, Department of Surgery, Medical University of Vienna, Vienna , Austria; c Hospices Civils de Lyon, Hopital Edouard-Herriot Service Central d‘Anatomie et Cytologie Pathologiques, Lyon , France; d Centre de Medecine Nucleaire, Universite Catholique de Louvain, Brussels , Belgium; e Department of Pathology, University of Kiel, Kiel , Germany; f B Unit of Surgery, Department of Surgery, University of Verona, Verona , Italy; g Department of Nuclear Medicine, Erasmus MC, Rotterdam , The Netherlands; h Department of Endocrine Oncology, University Hospital, Uppsala , Sweden; i Department of Internal Medicine, Division of Hepatology and Gastroenterology, Interdisciplinary Center of Metabolism and Endocrinology, Charite, Campus Virchow Hospital, University for Medicine Berlin, Berlin , Germany; j Service de Gastroenterologie-Pancreatologie, Pole des Maladies de l‘Appareil Digestif, Hopital Beaujon, Clichy , France; k Department of Pathology and Laboratory Medicine, Universita degli Studi, Parma, Italy; l Department of Endocrinology, Genoa University, Genoa , Italy

Published
2006

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