1. Central nervous system infections in the absence of cerebrospinal fluid pleocytosis
- Author
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Erdem, Hakan, Ozturk-Engin, Derya, Cag, Yasemin, Senbayrak, Seniha, Inan, Asuman, Kazak, Esra, Savasci, Umit, Elaldi, Nazif, Vahaboglu, Haluk, Hasbun, Rodrigo, Nechifor, Mihai, Tireli, Hulya, Kilicoglu, Gamze, Defres, Sylviane, Gulsun, Serda, Ceran, Nurgul, Crisan, Alexandru, Johansen, Isik Somuncu, Namiduru, Mustafa, Dayan, Saim, Kayabas, Uner, Parlak, Emine, Khalifa, Ahmad, Kursun, Ebru, Sipahi, Oguz Resat, Yemisen, Mucahit, Akbulut, Ayhan, Bitirgen, Mehmet, Popovic, Natasa, Kandemir, Bahar, Luca, Catalina, Parlak, Mehmet, Stahl, Jean Paul, Pehlivanoglu, Filiz, Simeon, Soline, Ulu-Kilic, Aysegul, Yasar, Kadriye, Yilmaz, Gulden, Yilmaz, Emel, Beovic, Bojana, Catroux, Melanie, Lakatos, Botond, Sunbul, Mustafa, Oncul, Oral, Alabay, Selma, Sahin-Horasan, Elif, Kose, Sukran, Shehata, Ghaydaa, Andre, Katell, Dragovac, Gorana, Gul, Hanefi Cem, Karakas, Ahmet, Chadapaud, Stéphane, Hansmann, Yves, Harxhi, Arjan, Kirova, Valerija, Masse-Chabredier, Isabelle, Oncu, Serkan, Sener, Alper, Tekin, Recep, Deveci, Ozcan, Ozkaya, Hacer Deniz, Karabay, Oguz, Agalar, Canan, Gencer, Serap, Karahocagil, Mustafa Kasim, Karsen, Hasan, Kaya, Selcuk, Pekok, Abdullah Umut, Celen, Mustafa Kemal, Deniz, Secil, Ulug, Mehmet, Demirdal, Tuna, Guven, Tumer, Bolukcu, Sibel, Avci, Meltem, Nayman-Alpat, Saygin, Yaşar, Kadriye, Pehlivanoʇlu, Filiz, Ates-Guler, Selma, Mutlu-Yilmaz, Esmeray, Tosun, Selma, Sirmatel, Fatma, Batirel, Ayşe, Öztoprak, Nefise, Kadanali, Ayten, Turgut, Huseyin, Baran, Ali Irfan, Karaahmetoglu, Gokhan, Sunnetcioglu, Mahmut, Haykir-Solay, Asli, Denk, Affan, Ayaz, Celal, Gorenek, Levent, Larsen, Lykke, Poljak, Mario, Barsic, Bruno, Argemi, Xavier, Sørensen, Signe Maj, Bohr, Anne Lisbeth, Tattevin, Pierre, Gunst, Jesper Damsgaard, Baštáková, Lenka, Jereb, Matjaž, Chehri, Mahtab, Beraud, Guillaume, Del Vecchio, Rosa Fontana, Maresca, Mauro, Yilmaz, Hava, Sharif-Yakan, Ahmad, Kanj, Souha Shararah, Korkmaz, Fatime, Komur, Suheyla, Coskuner, Seher Ayten, Ince, Nevin, Akkoyunlu, Yasemin, Halac, Gulistan, Nemli, Salih Atakan, Ak, Oznur, Gunduz, Alper, Gozel, Mustafa G., Hatipoglu, Mustafa, Cicek-Senturk, Gonul, Akcam, Fusun Z., Inkaya, Ahmet C., Sagmak-Tartar, Ayşe, Ersoy, Yasemin, Tuncer-Ertem, Gunay, Balkan, Ilker I., Cetin, Birsen, Ersoz, Gulden, Ozgunes, Nail, Yesilkaya, Aysegul, Erturk, Ayse, Gundes, Sibel, Turhan, Vedat, Yalci, Aysun, Aydin, Emsal, Diktas, Husrev, Ulcay, Asim, Seyman, Derya, Leblebicioglu, Hakan, [Erdem, Hakan -- Savasci, Umit] Gulhane Mil Med Acad, Dept Infect Dis & Clin Microbiol, Ankara, Turkey -- [Ozturk-Engin, Derya -- Senbayrak, Seniha -- Inan, Asuman] Haydarpasa Numune Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Cag, Yasemin] Lutfi Kirdar Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Kazak, Esra] Uludag Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Bursa, Turkey -- [Elaldi, Nazif] Cumhuriyet Univ, Sch Med, Dept Infect Dis & Clin Microbiol, Sivas, Turkey -- [Vahaboglu, Haluk] Medeniyet Univ, Goztepe Training & Res Hosp, Dept Infect Dis & Clin Microbiol, Istanbul, Turkey -- [Hasbun, Rodrigo] UT Hlth McGovern Med Sch, Dept Infect Dis, Houston, TX 77030 USA, Kart Yasar, Kadriye -- 0000-0003-2963-4894, Larsen, Lykke -- 0000-0002-4113-4182, VAHABOGLU, Haluk -- 0000-0001-8217-1767, Mikrobiyoloji, OMÜ, Çukurova Üniversitesi, Uludağ Üniversitesi/Tıp Fakültesi/Enfeksiyon Hastalıkları ve Klinik Mikrobiyoloji Anabilim Dalı, Kazak, Esra, AAG-8459-2021, and Ege Üniversitesi
- Subjects
0301 basic medicine ,Male ,Leukocytosis ,0302 clinical medicine ,CSF ,Encephalitis ,Leukocyte ,Meningitis ,Pleocytosis ,Neurosyphilis ,Diagnosis ,Pathology ,Medicine ,030212 general & internal medicine ,Brucella meningitis ,Middle aged ,biology ,Meningitis, Pneumococcal ,General Medicine ,Middle Aged ,Central nervous system infection ,Tıp ,ComputingMilieux_MANAGEMENTOFCOMPUTINGANDINFORMATIONSYSTEMS ,medicine.anatomical_structure ,Cerebrospinal fluid ,Bacterial Meningitides ,Cerebrospinal Fluid ,Infectious diseases ,Protein cerebrospinal fluid level ,Pneumococcal ,Female ,InformationSystems_MISCELLANEOUS ,Human ,Microbiology (medical) ,030106 microbiology ,Central nervous system ,Brucella ,Outcomes ,Cerebrospinal fluid pleocytosis ,Tuberculous meningitis ,Article ,lcsh:Infectious and parasitic diseases ,03 medical and health sciences ,Humans ,lcsh:RC109-216 ,Leukocytosis/cerebrospinal fluid ,Herpes simplex encephalitis ,business.industry ,ComputerSystemsOrganization_COMPUTER-COMMUNICATIONNETWORKS ,Herpetic meningoencephalitis ,Central Nervous System Infections/cerebrospinal fluid ,Pneumococcal meningitis ,Tuberculosis, meningeal ,medicine.disease ,biology.organism_classification ,Meningitis, Pneumococcal/cerebrospinal fluid ,ComputingMethodologies_PATTERNRECOGNITION ,Tuberculosis, Meningeal/cerebrospinal fluid ,Clinical feature ,Immunology ,business ,Central nervous system infections - Abstract
WOS: 000417628500023, PubMed ID: 29081366, Previous multicenter/multinational studies were evaluated to determine the frequency of the absence of cerebrospinal fluid pleocytosis in patients with central nervous system infections, as well as the clinical impact of this condition. It was found that 18% of neurosyphilis, 7.9% of herpetic meningoencephalitis, 3% of tuberculous meningitis, 1.7% of Brucella meningitis, and 0.2% of pneumococcal meningitis cases did not display cerebrospinal fluid pleocytosis. Most patients were not immunosuppressed. Patients without pleocytosis had a high rate of unfavorable outcomes and thus this condition should not be underestimated. (C) 2017 The Author(s). Published by Elsevier Ltd on behalf of International Society for Infectious Diseases., Grant-A-Starr Foundation, Grant-A-Starr Foundation.
- Published
- 2017