1. Angiogram-negative subarachnoid hemorrhage: outcomes data and review of the literature.
- Author
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Boswell S, Thorell W, Gogela S, Lyden E, and Surdell D
- Subjects
- Brain Ischemia etiology, Disease Progression, Female, Headache etiology, Humans, Hydrocephalus etiology, Male, Middle Aged, Odds Ratio, Predictive Value of Tests, Prognosis, Recurrence, Retrospective Studies, Risk Factors, Subarachnoid Hemorrhage complications, Time Factors, Vasospasm, Intracranial etiology, Cerebral Angiography, Subarachnoid Hemorrhage diagnostic imaging
- Abstract
Spontaneous subarachnoid hemorrhage (SAH) is most commonly caused by rupture of a saccular aneurysm or other structural pathologies. Occasionally, no structural cause for the hemorrhage can be identified by radiographic imaging. These hemorrhages, termed angiogram-negative SAH, are generally considered to have a better prognosis than aneurysmal SAH. Angiogram-negative SAH subgroups include benign perimesencephalic SAH (PMH) and aneurysmal-type SAH. Outcome data for these subgroups differ from those for the group as a whole. We report data for 31 patients who presented to our institution from 2006 to the present. We performed a retrospective chart review, and report outcome data that include rates of rehemorrhage, hydrocephalus, vasospasm, permanent ischemic deficits, headaches, and outcomes based on modified Rankin Scale scores. We also performed a review of the literature and meta-analysis of the data therein. We compared rates of complications in the PMH subgroup and the diffuse-type hemorrhage subgroup. The chart review revealed no poor outcomes and no rehemorrhages in the patients with PMH. In the diffuse hemorrhage subgroup, 1 patient had a rehemorrhage and 2 patients had a poor outcome. Our literature review found an OR of 6.23 for a good outcome for PMH versus diffuse-type hemorrhage, and an OR of 2.78 for rehemorrhage in PMH versus diffuse-type hemorrhage. Angiogram-negative SAH is not a benign entity. Complications are present but are significantly reduced, and outcomes are improved, compared with aneurysmal SAH., (Copyright © 2013 National Stroke Association. All rights reserved.)
- Published
- 2013
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