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ABSTRACT: Superficial spreading cervical squamous cell carcinoma (SCC) is a rare phenomenon with few cases reported in the literature. The present case report briefs the findings of superficial spreading cervical SCC in postmenopausal women. A 65-year-old postmenopausal woman presented with bleeding per-vaginum for 1–2 months. On examination, the cervix was healthy with no visible growth. She was diagnosed with an endometrial malignancy on magnetic resonance imaging. On endometrial and cervical biopsy, histopathology revealed cervical intraepithelial neoplasia III in ectocervix with SCC in endocervical and endometrial curetting. The patient underwent modified radical hysterectomy with bilateral pelvic lymphadenectomy and histopathology revealed superficially spreading cervical SCC with tumor cells involving endometrium, myometrium, paratubal, paraovarian, vaginal margins without extending to pelvic, and para-aortic lymph nodes. The patient was further managed successfully with adjuvant chemoradiotherapy. Superficial spreading cervical SCC is very rare phenomenon. Its spread is not only limited to endometrium but can extend to involve myometrium, paratubal, paraovarian, and vaginal tissues. [ABSTRACT FROM AUTHOR]

Objectives: We undertook this study to find out the spectrum of the cervical smear pattern along with the clinical profiles of patients who underwent cervical Papanicolaou (Pap) smear evaluation in our newly started tertiary care center. We also tried to find the possible clinical cause for unsatisfactory smears and factors for epithelial cell abnormality. Material and Methods: The present study was a retrospective observational study. Pap smears cases with their clinical findings mentioned on the requisition form and cytopathology observations were retrieved from the archives of the department of pathology. Fisher's exact test was used for statistical analysis. Results: Five hundred and ninety-four cases were included in the study. The most common age group was 3640 years. White discharge per vaginum was the most common clinical presentation. The negative for squamous intraepithelial lesions or malignancy was the most common interpretation (86.87%). Cervical erosion had statistically significant associations with unsatisfactory smears, while bacterial vaginosis had with satisfactory smears. Epithelial cell abnormality was seen in 4.62% patients. We observed a statistically significant association of cervical mucoid discharge, and inflammation with "no epithelial cell abnormality" cases, while postmenopausal bleeding was associated with "epithelial cell abnormality" cases. Conclusion: In the presence of clinical factors like cervical erosion, which may affect the quality of Pap smear, proper sampling techniques are to be used by health-care providers. The careful evaluation of Pap smears, especially in cases of cervical mucoid discharge, postmenopausal bleeding, and inflammatory smears is required to ensure that epithelial cell abnormalities are not overlooked. [ABSTRACT FROM AUTHOR]