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Your search keyword '"Slobodyanyuk, Evgeniy Y."' showing total 2 results
Start Over Author "Slobodyanyuk, Evgeniy Y." Topic chemical reactions
2 results on '"Slobodyanyuk, Evgeniy Y."'

1. Synthesis of Trifluoromethyl-Substituted 3-Azabicyclo[ n.1.0]alkanes: Advanced Building Blocks for Drug Discovery.

Author

Artamonov, Olexiy S., Slobodyanyuk, Evgeniy Y., Volochnyuk, Dmitriy M., Komarov, Igor V., Tolmachev, Andrey A., and Mykhailiuk, Pavel K.

Subjects
*ALKANE analysis, *COPPER chlorides, *CHEMICAL reactions, *AMIDE synthesis, *MOLECULAR structure of amides
Abstract

Five CF3-substituted 3-azabicyclo[ n.1.0]alkanes were synthesized by CuCl-mediated trifluoromethylcyclopropanation reaction of the corresponding cyclic enamides with CF3CHN2. [ABSTRACT FROM AUTHOR]

Published
2014
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2. Synthesis of Isomeric 6-Trifluoromethyl-3-azabicyclo[3.1.0]hexanes: Conformationally Restricted Analogues of 4-Trifluoromethylpiperidine.

Author

Artamonov, Olexiy S., Slobodyanyuk, Evgeniy Y., Shishkin, Oleg V., Komarov, Igor V., and Mykhailiuk, Pavel K.

Subjects
*ORGANIC synthesis, *ISOMERS, *HEXANE, *PIPERIDINE, *METHANE, *IMIDES, *RING formation (Chemistry), *CYCLOPROPANE, *CHEMICAL reactions
Abstract

Two isomeric conformationally restricted analogues of 4-trifluoromethylpiperidine were designed. The synthesis was performed in four steps from commercially available N-benzylmaleimide. The key reaction was the [3+2] cycloaddition between trifluoromethyldiazomethane and N-benzylmaleimide. [ABSTRACT FROM AUTHOR]

Published
2013
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