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Organosilicon compounds play a crucial role as essential building blocks and valuable organic molecules in various materials. They are extensively utilized as synthetic intermediates in chemical synthesis processes. Recent studies have highlighted the multifaceted role of silicon compounds, showcasing their significance not only as reactive participants or products but also as potent catalysts in various chemical reactions, as reported by researchers. In this comprehensive review, our objective is to provide a summary of recent advancements in synthesizing various organosilicon compounds in formation of silicon–carbon, silicon–oxygen, silicon–nitrogen and explore the applications of siliconic materials as catalysts in polymerization, reduction, and isomerization processes. Emphasizing the significant potential of this methodology, we aspire to inspire further research and applications in this rapidly emerging field. Furthermore, this review covers over 50 years of research on organosilicon chemistry in CCERCI under supervision of Prof. Seyed Mohammad Bolourtchian. [ABSTRACT FROM AUTHOR]

The first general procedure is described for the synthesis of novel bisarylmethylidenes of 2-methoxy-2-methyl-1,3-dioxan-5-one 1. Thus, several derivatives of 3 are obtained rapidly in high yields by reacting 1 with different aldehydes in the presence of catalytic quantities of pyrrolidine in EtOH at room temperature. Upon completion of the reactions, products are obtained directly by spontaneous precipitation avoiding time consuming and expensive chromatographic separations. All products were characterized by proton and carbon NMR spectroscopy methods, and in one case, the proposed structure was elucidated by X-ray crystallography, confirming the Z stereochemistry for the olefinic C=C bonds. Due to showing different colours in solid and solution states, products were studied for their photophysical properties as well. [ABSTRACT FROM AUTHOR]

A one-pot cyclocondensation of 1,3-dioxane-5-one (1) with malononitrile and aromatic aldehydes in aqueous sodium hydroxide under ultrasonic irradiation furnishes a series of pyrano[3,2-d][1,3]dioxin derivatives 3. Reactions are completed after a few minutes and the precipitated products are purified by simple crystallization from ethanol. The reaction with ethyl cyanoacetate instead of malononitrile gives the respective analogous products in high yields. [ABSTRACT FROM AUTHOR]

A facile procedure is developed for one-pot synthesis of a new group of dicyanoanilines. Tetrahydro-4H-thiopyran-4-one,1, undergoes a pseudo four-component reaction with various aldehydes bearing different groups and two equivalents of malononitrile in aqueous media in the presence of triethylamine (Et3N). As a result, novel thiopyran-fused dicyanoanilines4are formed efficiently in the reaction mixtures in 90–97% yield within 9–12 h mixing at 40°C. Due to the polarity of the medium, products precipitate in the mixture spontaneously allowing for easy purification by recrystallization avoiding cumbersome chromatographic separations. Characterization of the products was performed by spectroscopic methods and, in one case, was further supported by X-ray crystallographic experiments. [ABSTRACT FROM AUTHOR]

1-Methylpiperidin-4-one and its sulfur and oxygen analogues undergo individual facile pseudo four-component reactions with two folds of malononitrile and various aldehydes by using ultrasonic irradiation and deficient quantities of pyrrolidine. As a consequence, ortho -aminocarbonitrile products are formed efficiently in the mixture within 1–2 min of irradiation. Alternatively, the same mixtures of the reactants would lead to direct high-yield formation of dicyanoanilines, a group of products which are also attainable in a stepwise manner starting from the respective ortho -aminocarbonitriles. [ABSTRACT FROM AUTHOR]

Catalytic quantities (2 mol%) of a complex of cobalt containing guanidine and 2,6-pyridinedicarboxylic acid ligands (PDAG-Co) were used for the efficient three-component Mannich reactions of tetrahydro-4-pyranone ( 1) with different aromatic aldehydes and aniline derivatives in a one-pot process. Reactions rapidly gave high yields of the corresponding three-substituted tetrahydro-4-pyranones at room temperature. Spectroscopic and X-ray analyses support the formation of anti diastereomers as the major or sole products of the reactions. [ABSTRACT FROM AUTHOR]

An efficient and room-temperature procedure is developed for high yield synthesis of novel α,β-unsaturated derivatives of thiopyran 3 directly from ketone 1 and various aldehydes in the presence of catalytic quantities of TMSNMe2 and MgBr2⋅OEt2 under solvent-free conditions. The main advantage of the procedure is that the formation of the undesired bis by-products is minimized. In addition, the procedure is applicable to other enolizable carbocyclic and acyclic ketones. [ABSTRACT FROM AUTHOR]

A tandem aldol condensation - Diels-Alder cycloaddition process is developed to combine isophorone (3,5,5-trimethyl-2-cyclohexen-1-one), aromatic aldehydes, and methyl acrylate in an efficient stereoselective one-pot synthesis of methyl (2R,3S)-rel-3-aryl-1,2,3,4,5,6,7,8-octahydro-6,6-dimethyl-8-oxo-2-naphthalenecarboxylates using trace quantities of ammonium ions under aqueous conditions. Alternatively, the respective conjugated dienes which are formed in situ from the condensation of isophorone with the aldehydes can also react with methyl acrylate in a stepwise fashion leading to the same products. [ABSTRACT FROM AUTHOR]