1. Total syntheses of bengamides B and E
- Author
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Kinder, Frederick R., Jr., Wattanasin, Sompong, Versace, Richard W., Bair, Kenneth W., Bontempo, John, Green, Michael A., Lu, Yansong J., Marepalli, H. Rao, Phillips, Penny E., Roche, Didier, Tran, Long D., Wang, RunMing, Waykole, Liladhar, Xu, David D., and Zabludoff, Sonya
- Subjects
Chemistry, Organic -- Research ,Amides -- Physiological aspects ,Lactones -- Physiological aspects ,Chromium -- Physiological aspects ,Aldehydes -- Physiological aspects ,Biological sciences ,Chemistry - Abstract
Research has been conducted on the cytotoxic marine natural products bengamides B and E. The preparation of these bengamides has been carried out via the amide coupling of a protected polyhydroxylated lactone intermediate with the substituted aminocaprolactam intermediate and the results are presented.
- Published
- 2001