1. Application of nano‐graphene oxide as nontoxic disinfectant against alpha and betacoronaviruses
- Author
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Hee-Chun Chung, Yong Ho Park, Van Giap Nguyen, Cheong Ung Kim, Daesub Song, Kyung-Sun Kang, Hai-Quynh Do, Jaechul Ryu, Bong-Kyun Park, and Aeri Kong
- Subjects
General Veterinary ,Chemistry ,nano‐graphene oxide ,Veterinary medicine ,Disinfectant ,Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) ,viruses ,Short Communication ,coronaviruses ,Alpha (ethology) ,virus diseases ,Virology ,Antiviral Agents ,Virus ,Biological fluid ,Nanostructures ,Coronavirus ,Porcine epidemic diarrhoea virus ,SF600-1100 ,antiviral activity ,Humans ,Graphite ,Severe acute respiratory syndrome coronavirus ,Bovine coronavirus ,Disinfectants - Abstract
New viruses are continuously emerging and recently there have been many great concerns on severe acute respiratory syndrome coronavirus (SARS‐CoV‐2). Nanographene oxide (nanoGO) has received much attention and is widely investigated to be utilised in therapy for infectious diseases by viruses. Thus, antiviral activity of nanoGO was evaluated using the porcine epidemic diarrhoea virus (PEDV), bovine coronavirus (BCoV), and SARS‐CoV‐2, which are all Alpha‐ and Beta‐coronavirus. In a virus inhibition assay, the three viruses were inhibited by nanoGO in a dose‐dependent manner, including attempts in the presence of high serum solution which partially mimicked biological fluid., Our results indicated that nanoGO material revealed different levels of antiviral activity against different viruses.
- Published
- 2021